Sphera Funds Management Ltd.
- SEC CIK
- 0001496201
- Latest filing
- Aug 14, 2026
Holdings in Q1 2022
Holdings as of Mar 31, 2022, filed May 16, 2022. Long positions only; changes compare share counts with Q4 2021.
- Positions
- 59
- −26 vs. Q4 2021
- Portfolio value
- $596.5M
- −$245.4M (−29.1%) vs. Q4 2021
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| AZNAstraZeneca PLC | SPONSORED ADR | 836,817 | $55.5M | 9.3% | −218,650−20.7% | Reduced | History |
| JNJJohnson & Johnson | Stock | 295,023 | $52.3M | 8.8% | +139,900+90.2% | Added | History |
| SNYSanofi | SPONSORED ADR | 972,415 | $49.9M | 8.4% | −110,985−10.2% | Reduced | History |
| ABBVAbbVie Inc. | Stock | 190,994 | $31.0M | 5.2% | −273,200−58.9% | Reduced | History |
| PFEPfizer Inc | Stock | 515,070 | $26.7M | 4.5% | +286,542+125.4% | Added | History |
| NVONovo Nordisk A S | ADR | 237,400 | $26.4M | 4.4% | +237,400 | New | History |
| SWTXSpringWorks Therapeutics, Inc. | COM | 460,025 | $26.0M | 4.4% | +117,459+34.3% | Added | History |
| MRKMerck & Co., Inc. | Stock | 278,200 | $22.8M | 3.8% | −68,223−19.7% | Reduced | History |
| SNDXSyndax Pharmaceuticals Inc | COM | 1,277,413 | $22.2M | 3.7% | +100,828+8.6% | Added | History |
| LLYEli Lilly & Co | Stock | 70,295 | $20.1M | 3.4% | −89,400−56.0% | Reduced | History |
| BMRNBiomarin Pharmaceutical Inc | COM | 211,326 | $16.3M | 2.7% | −5,651−2.6% | Reduced | History |
| KYMRKymera Therapeutics, Inc. | COM | 368,061 | $15.6M | 2.6% | +49,394+15.5% | Added | History |
| ISEEIVERIC bio, Inc. | COM | 774,130 | $13.0M | 2.2% | +289,129+59.6% | Added | History |
| GNRCGenerac Holdings Inc. | Stock | 42,211 | $12.5M | 2.1% | +154+0.4% | Added | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 521,947 | $11.5M | 1.9% | +98,699+23.3% | Added | History |
| AMDAdvanced Micro Devices Inc | Stock | 100,000 | $10.9M | 1.8% | +100,000 | New | History |
| MRUSMerus N.V. | COM | 409,141 | $10.8M | 1.8% | +68,190+20.0% | Added | History |
| ZIMZIM Integrated Shipping Services Ltd. | SHS | 148,000 | $10.8M | 1.8% | +148,000 | New | History |
| KURAKura Oncology, Inc. | COM | 618,244 | $9.94M | 1.7% | −213,994−25.7% | Reduced | History |
| CCCCC4 Therapeutics, Inc. | COM STK | 362,528 | $8.79M | 1.5% | −35,941−9.0% | Reduced | History |
| KDNYChinook Therapeutics, Inc. | COM | 493,677 | $8.08M | 1.4% | +382,024+342.2% | Added | History |
| ALTAltimmune, Inc. | COM NEW | 1,306,953 | $7.96M | 1.3% | +62,712+5.0% | Added | History |
| RLMDRelmada Therapeutics, Inc. | COM | 291,252 | $7.86M | 1.3% | −186,956−39.1% | Reduced | History |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | 832,878 | $7.82M | 1.3% | +10.0% | Added | History |
| KROSKeros Therapeutics, Inc. | COM | 139,581 | $7.59M | 1.3% | +19,900+16.6% | Added | History |
| PERIPerion Network Ltd. | SHS NEW | 306,051 | $6.88M | 1.2% | +81,051+36.0% | Added | History |
| IMUXImmunic, Inc. | COM | 583,206 | $6.59M | 1.1% | −83,396−12.5% | Reduced | History |
| VTGNVistagen Therapeutics, Inc. | COM NEW | 4,951,423 | $6.14M | 1.0% | +926,485+23.0% | Added | History |
| VVisa Inc. | Stock | 25,200 | $5.59M | 0.9% | +25,200 | New | History |
| ABNBAirbnb, Inc. | Stock | 30,000 | $5.15M | 0.9% | −17,689−37.1% | Reduced | History |
| IMTXImmatics N.V. | SHS | 621,925 | $4.97M | 0.8% | 00.0% | Unchanged | History |
| RUNSunrun Inc. | COM | 150,000 | $4.56M | 0.8% | +150,000 | New | History |
| CSTECaesarstone Ltd. | ORD SHS | 428,046 | $4.50M | 0.8% | −216,100−33.5% | Reduced | History |
| MAMastercard Inc | Stock | 12,100 | $4.32M | 0.7% | +12,100 | New | History |
| Fiverr Intl Ltd33835LAA3 | NOTE 11/0 | 4,951,000 | $4.23M | 0.7% | −8,049,000−61.9% | Reduced | – |
| ALNYAlnylam Pharmaceuticals, Inc. | COM | 24,768 | $4.04M | 0.7% | +24,768 | New | History |
| NAUTNautilus Biotechnology, Inc. | COM | 840,000 | $3.65M | 0.6% | +40,000+5.0% | Added | History |
| REPLReplimune Group, Inc. | COM | 212,640 | $3.61M | 0.6% | +212,640 | New | History |
| FATEFate Therapeutics Inc | COM | 89,425 | $3.47M | 0.6% | −96,051−51.8% | Reduced | History |
| VRNAVerona Pharma plc | SPONSORED ADS | 666,339 | $3.33M | 0.6% | −134,917−16.8% | Reduced | History |
| FIVNFive9, Inc. | COM | 29,699 | $3.28M | 0.5% | −55,857−65.3% | Reduced | History |
| KZRKezar Life Sciences, Inc. | COM | 187,599 | $3.12M | 0.5% | −149,694−44.4% | Reduced | History |
| ASNDAscendis Pharma A/S | SPONSORED ADR | 26,529 | $3.11M | 0.5% | +26,529 | New | History |
| Ironsource LtdM5R75Y101 | CL A ORD SHS | 620,000 | $2.98M | 0.5% | +620,000 | New | – |
| VINCVincerx Pharma, Inc. | COM NEW | 720,161 | $2.88M | 0.5% | 00.0% | Unchanged | History |
| CATCaterpillar Inc | Stock | 12,000 | $2.67M | 0.4% | +12,000 | New | History |
| HOWLWerewolf Therapeutics, Inc. | COM | 584,203 | $2.57M | 0.4% | −64,188−9.9% | Reduced | History |
| SSentinelOne, Inc. | CL A | 65,000 | $2.52M | 0.4% | −134,824−67.5% | Reduced | History |
| KRYSKrystal Biotech, Inc. | COM | 25,310 | $1.68M | 0.3% | +25,310 | New | History |
| Bio Green Med Solution, Inc.23254L603 | COM | 508,322 | $1.55M | 0.3% | 00.0% | Unchanged | – |
| Magic Software Enterprises L559166103 | ORD | 81,293 | $1.40M | 0.2% | +23,589+40.9% | Added | – |
| LIANYLianBio | SPONSORED ADS | 275,007 | $1.02M | 0.2% | 00.0% | Unchanged | History |
| AYLAOld Ayala, Inc | COM | 250,000 | $995.0K | 0.2% | 00.0% | Unchanged | History |
| ONCROncorus, Inc. | COM | 540,258 | $962.0K | 0.2% | −30,946−5.4% | Reduced | History |
| OTMOOtonomo Technologies Ltd. | ORDINARY SHARES | 391,863 | $772.0K | 0.1% | −201,787−34.0% | Reduced | History |
| Nice Sys Inc65366HAB9 | NOTE 1.250% 1/1 | 250,000 | $662.0K | 0.1% | 00.0% | Unchanged | – |
| TEADTeads Holding Co. | COM | 52,531 | $564.0K | 0.1% | −378,663−87.8% | Reduced | History |
| ARBEArbe Robotics Ltd. | COM | 43,165 | $300.0K | 0.1% | −77,235−64.1% | Reduced | History |
| Immatics N.V.N44445117 | *W EXP 07/01/202 | 100,000 | $175.0K | <0.1% | 00.0% | Unchanged | – |
Options (6)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| Invesco QQQ Trust Series I46090E103 | ETF | $45.7M | – |
| FIVNFive9, Inc. | COM | – | $27.5M |
| TEVATeva Pharmaceutical Industries Ltd | SPONSORED ADS | $1.97M | $17.7M |
| SWTXSpringWorks Therapeutics, Inc. | COM | – | $7.05M |
| RUNSunrun Inc. | COM | – | $6.92M |
| Airbnb Inc009066901 | CALL | – | $4.17M |
Sold out since Q4 2021 (38)
Positions held at the end of Q4 2021 that are gone from this filing.
| Security | Class | Shares in Q4 2021 | Value in Q4 2021 | % of portfolio in Q4 2021 | History |
|---|---|---|---|---|---|
| Wix.com Ltd.92940WAD1 | NOTE 8/1 | 18,959,000 | $17.3M | 2.1% | – |
| MSFTMicrosoft Corp | Stock | 50,536 | $17.0M | 2.0% | History |
| AMZNAmazon Com Inc | Stock | 4,200 | $14.0M | 1.7% | History |
| METAMeta Platforms, Inc. | Stock | 41,622 | $14.0M | 1.7% | History |
| PANWPalo Alto Networks Inc | Stock | 24,000 | $13.4M | 1.6% | History |
| BURLBurlington Stores, Inc. | COM | 41,501 | $12.1M | 1.4% | History |
| VRNTVerint Systems Inc | COM | 200,000 | $10.5M | 1.2% | History |
| ARYDARYA Sciences Acquisition Corp IV | CL A | 1,000,000 | $9.93M | 1.2% | History |
| LESLLeslie's, Inc. | COM | 372,569 | $8.81M | 1.0% | History |
| LENZLENZ Therapeutics, Inc. | COM | 663,194 | $8.24M | 1.0% | History |
| ASANAsana, Inc. | CL A | 96,500 | $7.19M | 0.9% | History |
| ZLABZai Lab Ltd | ADR | 111,641 | $7.02M | 0.8% | History |
| CLDXCelldex Therapeutics, Inc. | COM NEW | 166,766 | $6.44M | 0.8% | History |
| EPIXESSA Pharma Inc. | COM NEW | 422,461 | $6.00M | 0.7% | History |
| IDYAIDEAYA Biosciences, Inc. | COM | 235,695 | $5.57M | 0.7% | History |
| IOVAIovance Biotherapeutics, Inc. | COM | 281,769 | $5.38M | 0.6% | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 190,525 | $4.40M | 0.5% | History |
| STROSutro Biopharma, Inc. | COM | 281,702 | $4.19M | 0.5% | History |
| KALVKalVista Pharmaceuticals, Inc. | COM | 316,200 | $4.18M | 0.5% | History |
| ALLTAllot Ltd. | SHS | 340,912 | $4.05M | 0.5% | History |
| OMGAOmega Therapeutics, Inc. | COMMON STOCK | 352,948 | $4.00M | 0.5% | History |
| BCABBioAtla, Inc. | COM | 180,006 | $3.53M | 0.4% | History |
| CAMTCamtek Ltd | ORD | 75,000 | $3.45M | 0.4% | History |
| PNTPOINT Biopharma Global Inc. | COM | 592,592 | $3.32M | 0.4% | History |
| TPTXTurning Point Therapeutics, Inc. | COM | 68,734 | $3.28M | 0.4% | History |
| BIIBBiogen Inc. | COM | 13,000 | $3.12M | 0.4% | History |
| INBXInhibrx Biosciences, Inc. | COM | 61,931 | $2.71M | 0.3% | History |
| ACETAdicet Bio, Inc. | COM | 150,000 | $2.62M | 0.3% | History |
| CMPXCompass Therapeutics, Inc. | COM | 700,000 | $2.22M | 0.3% | History |
| BCLS Acquisition CorpG0904B105 | COM CL A | 216,250 | $2.13M | 0.3% | – |
| ARYEARYA Sciences Acquisition Corp V | CLASS A ORD SHS | 200,000 | $1.94M | 0.2% | History |
| ARGXArgenx SE | SPONSORED ADR | 4,291 | $1.50M | 0.2% | History |
| ANNXAnnexon, Inc. | COM | 123,637 | $1.42M | 0.2% | History |
| DYNDyne Therapeutics, Inc. | COM | 105,204 | $1.25M | 0.1% | History |
| CYTCyteir Therapeutics, Inc. | COM | 98,860 | $1.12M | 0.1% | History |
| VRTXVertex Pharmaceuticals Inc | Stock | 4,411 | $969.0K | 0.1% | History |
| LVTXLAVA Therapeutics NV | SHS | 137,857 | $758.0K | 0.1% | History |
| Outlook Therapeutics, Inc.69012T115 | *W EXP 02/18/202 | 129,500 | $15.0K | <0.1% | – |