Great Point Partners LLC
- SEC CIK
- 0001281446
- Latest filing
- Aug 14, 2026
Holdings in Q3 2025
Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.
- Positions
- 28
- +2 vs. Q2 2025
- Portfolio value
- $239.5M
- +$85.7M (+55.7%) vs. Q2 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| AMLXAmylyx Pharmaceuticals, Inc. | COM | 1,700,000 | $23.1M | 9.6% | −300,000−15.0% | Reduced | History |
| RZLTRezolute, Inc. | COM NEW | 2,451,809 | $23.0M | 9.6% | −581,653−19.2% | Reduced | History |
| NKTRNektar Therapeutics | COM NEW | 300,000 | $17.1M | 7.1% | +300,000 | New | History |
| ZURAZura Bio Ltd | CLASS A ORD SHS | 3,815,930 | $16.5M | 6.9% | +645,736+20.4% | Added | History |
| SLNOSoleno Therapeutics Inc | COM | 225,000 | $15.2M | 6.4% | +225,000 | New | History |
| ASNDAscendis Pharma A/S | SPONSORED ADR | 75,000 | $14.9M | 6.2% | +75,000 | New | History |
| ABVXAbivax S.A. | SPONSORED ADS | 150,000 | $12.7M | 5.3% | −1,141,617−88.4% | Reduced | History |
| APGEApogee Therapeutics, Inc. | COM | 304,000 | $12.1M | 5.0% | +304,000 | New | History |
| DNTHDianthus Therapeutics, Inc. | COM | 265,803 | $10.5M | 4.4% | +265,803 | New | History |
| CYTKCytokinetics Inc | COM NEW | 150,000 | $8.24M | 3.4% | 00.0% | Unchanged | History |
| IMVTImmunovant, Inc. | COM | 500,000 | $8.06M | 3.4% | +237,824+90.7% | Added | History |
| XENEXenon Pharmaceuticals Inc. | COM | 200,000 | $8.03M | 3.4% | 00.0% | Unchanged | History |
| NGNENeurogene Inc. | COM | 446,814 | $7.74M | 3.2% | −39,045−8.0% | Reduced | History |
| EPRXEupraxia Pharmaceuticals Inc. | COM | 1,200,000 | $7.08M | 3.0% | +1,200,000 | New | History |
| UPBUpstream Bio, Inc. | COM | 300,000 | $5.64M | 2.4% | 00.0% | Unchanged | History |
| JBIOJade Biosciences, Inc. | COM NEW | 632,599 | $5.46M | 2.3% | +134,545+27.0% | Added | History |
| IONSIonis Pharmaceuticals Inc | COM | 80,000 | $5.23M | 2.2% | −420,000−84.0% | Reduced | History |
| AKROAkero Therapeutics, Inc. | COM | 103,848 | $4.93M | 2.1% | 00.0% | Unchanged | History |
| TSHATaysha Gene Therapies, Inc. | COM SHS | 1,500,000 | $4.91M | 2.0% | 00.0% | Unchanged | History |
| CNTXContext Therapeutics Inc. | COM | 4,683,711 | $4.54M | 1.9% | 00.0% | Unchanged | History |
| PHVSPharvaris N.V. | COM | 155,105 | $3.87M | 1.6% | +155,105 | New | History |
| DBVTDBV Technologies S.A. | SPONSORED ADS | 378,594 | $3.79M | 1.6% | +3,915+1.0% | Added | History |
| LEGNLegend Biotech Corp | SPONSORED ADS | 113,460 | $3.70M | 1.5% | −236,540−67.6% | Reduced | History |
| ORKAOruka Therapeutics, Inc. | COM | 183,330 | $3.53M | 1.5% | +183,330 | New | History |
| UNCYUnicycive Therapeutics, Inc. | COM NEW | 796,558 | $3.47M | 1.4% | 00.0% | Unchanged | History |
| SANASana Biotechnology, Inc. | COM | 700,000 | $2.48M | 1.0% | +700,000 | New | History |
| ABSIAbsci Corp | COM | 796,438 | $2.42M | 1.0% | +796,438 | New | History |
| PLRXPliant Therapeutics, Inc. | COM | 850,000 | $1.26M | 0.5% | 00.0% | Unchanged | History |
Options (2)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
Sold out since Q2 2025 (8)
Positions held at the end of Q2 2025 that are gone from this filing.
| Security | Class | Shares in Q2 2025 | Value in Q2 2025 | % of portfolio in Q2 2025 | History |
|---|---|---|---|---|---|
| AKBAAkebia Therapeutics, Inc. | COM | 1,985,915 | $7.23M | 4.7% | History |
| EOLSEvolus, Inc. | COM | 720,118 | $6.63M | 4.3% | History |
| ACLXArcellx, Inc. | COMMON STOCK | 100,000 | $6.58M | 4.3% | History |
| KALVKalVista Pharmaceuticals, Inc. | COM | 323,170 | $3.65M | 2.4% | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 225,000 | $2.96M | 1.9% | History |
| SRRKScholar Rock Holding Corp | COM | 61,607 | $2.18M | 1.4% | History |
| PMNProMIS Neurosciences Inc. | COM | 2,645,128 | $1.28M | 0.8% | History |
| BBOTBridgeBio Oncology Therapeutics, Inc. | CL A ORD SHS | 29,381 | $312.0K | 0.2% | History |