Great Point Partners LLC
- SEC CIK
- 0001281446
- Latest filing
- Aug 14, 2026
Holdings in Q3 2025
Holdings as of Sep 30, 2025, filed Nov 14, 2025. Long positions only; changes compare share counts with Q2 2025.
- Positions
- 28
- +2 vs. Q2 2025
- Portfolio value
- $239.5M
- +$85.7M (+55.7%) vs. Q2 2025
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| PLRXPliant Therapeutics, Inc. | COM | 850,000 | $1.26M | 0.5% | 00.0% | Unchanged | History |
| ABSIAbsci Corp | COM | 796,438 | $2.42M | 1.0% | +796,438 | New | History |
| SANASana Biotechnology, Inc. | COM | 700,000 | $2.48M | 1.0% | +700,000 | New | History |
| UNCYUnicycive Therapeutics, Inc. | COM NEW | 796,558 | $3.47M | 1.4% | 00.0% | Unchanged | History |
| ORKAOruka Therapeutics, Inc. | COM | 183,330 | $3.53M | 1.5% | +183,330 | New | History |
| LEGNLegend Biotech Corp | SPONSORED ADS | 113,460 | $3.70M | 1.5% | −236,540−67.6% | Reduced | History |
| DBVTDBV Technologies S.A. | SPONSORED ADS | 378,594 | $3.79M | 1.6% | +3,915+1.0% | Added | History |
| PHVSPharvaris N.V. | COM | 155,105 | $3.87M | 1.6% | +155,105 | New | History |
| CNTXContext Therapeutics Inc. | COM | 4,683,711 | $4.54M | 1.9% | 00.0% | Unchanged | History |
| TSHATaysha Gene Therapies, Inc. | COM SHS | 1,500,000 | $4.91M | 2.0% | 00.0% | Unchanged | History |
| AKROAkero Therapeutics, Inc. | COM | 103,848 | $4.93M | 2.1% | 00.0% | Unchanged | History |
| IONSIonis Pharmaceuticals Inc | COM | 80,000 | $5.23M | 2.2% | −420,000−84.0% | Reduced | History |
| JBIOJade Biosciences, Inc. | COM NEW | 632,599 | $5.46M | 2.3% | +134,545+27.0% | Added | History |
| UPBUpstream Bio, Inc. | COM | 300,000 | $5.64M | 2.4% | 00.0% | Unchanged | History |
| EPRXEupraxia Pharmaceuticals Inc. | COM | 1,200,000 | $7.08M | 3.0% | +1,200,000 | New | History |
| NGNENeurogene Inc. | COM | 446,814 | $7.74M | 3.2% | −39,045−8.0% | Reduced | History |
| XENEXenon Pharmaceuticals Inc. | COM | 200,000 | $8.03M | 3.4% | 00.0% | Unchanged | History |
| IMVTImmunovant, Inc. | COM | 500,000 | $8.06M | 3.4% | +237,824+90.7% | Added | History |
| CYTKCytokinetics Inc | COM NEW | 150,000 | $8.24M | 3.4% | 00.0% | Unchanged | History |
| DNTHDianthus Therapeutics, Inc. | COM | 265,803 | $10.5M | 4.4% | +265,803 | New | History |
| APGEApogee Therapeutics, Inc. | COM | 304,000 | $12.1M | 5.0% | +304,000 | New | History |
| ABVXAbivax S.A. | SPONSORED ADS | 150,000 | $12.7M | 5.3% | −1,141,617−88.4% | Reduced | History |
| ASNDAscendis Pharma A/S | SPONSORED ADR | 75,000 | $14.9M | 6.2% | +75,000 | New | History |
| SLNOSoleno Therapeutics Inc | COM | 225,000 | $15.2M | 6.4% | +225,000 | New | History |
| ZURAZura Bio Ltd | CLASS A ORD SHS | 3,815,930 | $16.5M | 6.9% | +645,736+20.4% | Added | History |
| NKTRNektar Therapeutics | COM NEW | 300,000 | $17.1M | 7.1% | +300,000 | New | History |
| RZLTRezolute, Inc. | COM NEW | 2,451,809 | $23.0M | 9.6% | −581,653−19.2% | Reduced | History |
| AMLXAmylyx Pharmaceuticals, Inc. | COM | 1,700,000 | $23.1M | 9.6% | −300,000−15.0% | Reduced | History |
Options (2)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
Sold out since Q2 2025 (8)
Positions held at the end of Q2 2025 that are gone from this filing.
| Security | Class | Shares in Q2 2025 | Value in Q2 2025 | % of portfolio in Q2 2025 | History |
|---|---|---|---|---|---|
| AKBAAkebia Therapeutics, Inc. | COM | 1,985,915 | $7.23M | 4.7% | History |
| EOLSEvolus, Inc. | COM | 720,118 | $6.63M | 4.3% | History |
| ACLXArcellx, Inc. | COMMON STOCK | 100,000 | $6.58M | 4.3% | History |
| KALVKalVista Pharmaceuticals, Inc. | COM | 323,170 | $3.65M | 2.4% | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 225,000 | $2.96M | 1.9% | History |
| SRRKScholar Rock Holding Corp | COM | 61,607 | $2.18M | 1.4% | History |
| PMNProMIS Neurosciences Inc. | COM | 2,645,128 | $1.28M | 0.8% | History |
| BBOTBridgeBio Oncology Therapeutics, Inc. | CL A ORD SHS | 29,381 | $312.0K | 0.2% | History |