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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q2 2025

Holdings as of Jun 30, 2025, filed Aug 14, 2025. Long positions only; changes compare share counts with Q1 2025.

Institution overview
Positions
26
−5 vs. Q1 2025
Portfolio value
$153.8M
−$30.2M (−16.4%) vs. Q1 2025
Filed
Aug 14, 2025
SEC
Holdings of Great Point Partners LLC in Q2 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
IONSIonis Pharmaceuticals IncCOM500,000$19.8M12.8%+250,000+100.0%AddedHistory
RZLTRezolute, Inc.COM NEW3,033,462$13.5M8.8%+2,200,420+264.1%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM2,000,000$12.8M8.3%+188,004+10.4%AddedHistory
LEGNLegend Biotech CorpSPONSORED ADS350,000$12.4M8.1%+211,760+153.2%AddedHistory
ABVXAbivax S.A.SPONSORED ADS1,291,617$9.88M6.4%−346,494−21.2%ReducedHistory
NGNENeurogene Inc.COM485,859$7.26M4.7%+14,895+3.2%AddedHistory
AKBAAkebia Therapeutics, Inc.COM1,985,915$7.23M4.7%−2,987,925−60.1%ReducedHistory
EOLSEvolus, Inc.COM720,118$6.63M4.3%−224,625−23.8%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK100,000$6.58M4.3%+55,000+122.2%AddedHistory
XENEXenon Pharmaceuticals Inc.COM200,000$6.26M4.1%−45,272−18.5%ReducedHistory
AKROAkero Therapeutics, Inc.COM103,848$5.54M3.6%+103,848NewHistory
JBIOJade Biosciences, Inc.COM NEW498,054$4.98M3.2%+498,054NewHistory
CYTKCytokinetics IncCOM NEW150,000$4.96M3.2%−220,000−59.5%ReducedHistory
IMVTImmunovant, Inc.COM262,176$4.19M2.7%−112,824−30.1%ReducedHistory
UNCYUnicycive Therapeutics, Inc.COM NEW796,558$3.80M2.5%−301,442−27.5%ReducedConverted for a 1-for-10 splitHistory
KALVKalVista Pharmaceuticals, Inc.COM323,170$3.65M2.4%−691,197−68.1%ReducedHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,500,000$3.46M2.3%+1,500,000NewHistory
DBVTDBV Technologies S.A.SPONSORED ADS374,679$3.43M2.2%+374,679NewHistory
ZURAZura Bio LtdCLASS A ORD SHS3,170,194$3.33M2.2%00.0%UnchangedHistory
UPBUpstream Bio, Inc.COM300,000$3.29M2.1%00.0%UnchangedHistory
CNTXContext Therapeutics Inc.COM4,683,711$3.07M2.0%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS225,000$2.96M1.9%+75,298+50.3%AddedHistory
SRRKScholar Rock Holding CorpCOM61,607$2.18M1.4%+61,607NewHistory
PMNProMIS Neurosciences Inc.COM2,645,128$1.28M0.8%00.0%UnchangedHistory
PLRXPliant Therapeutics, Inc.COM850,000$986.0K0.6%00.0%UnchangedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS29,381$312.0K0.2%−344,452−92.1%ReducedHistory

Sold out since Q1 2025 (10)

Positions held at the end of Q1 2025 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q1 2025
SecurityClassShares in Q1 2025Value in Q1 2025% of portfolio in Q1 2025History
VRDNViridian Therapeutics, Inc.COM750,000$10.1M5.5%History
MRUSMerus N.V.COM237,156$9.98M5.4%History
ASNDAscendis Pharma A/SSPONSORED ADR50,000$7.79M4.2%History
DVAXDynavax Technologies CorpCOM NEW595,879$7.73M4.2%History
DNTHDianthus Therapeutics, Inc.COM275,000$4.99M2.7%History
PCVXVaxcyte, Inc.COM115,517$4.36M2.4%History
AUTLAutolus Therapeutics plcSPON ADS2,728,910$4.23M2.3%History
BEAMBeam Therapeutics Inc.COM175,562$3.43M1.9%History
MREOMereo BioPharma Group plcSPON ADS1,275,000$2.87M1.6%History
VYGRVoyager Therapeutics, Inc.COM626,275$2.12M1.2%History