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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q2 2023

Holdings as of Jun 30, 2023, filed Aug 14, 2023. Long positions only; changes compare share counts with Q1 2023.

Institution overview
Positions
36
−6 vs. Q1 2023
Portfolio value
$499.2M
−$6.74M (−1.3%) vs. Q1 2023
Filed
Aug 14, 2023
SEC
Holdings of Great Point Partners LLC in Q2 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
ALPNAlpine Immune Sciences, Inc.COM3,363,688$34.6M6.9%−377,073−10.1%ReducedHistory
RAREUltragenyx Pharmaceutical Inc.COM677,426$31.2M6.3%00.0%UnchangedHistory
PCVXVaxcyte, Inc.COM589,211$29.4M5.9%−70,000−10.6%ReducedHistory
PLRXPliant Therapeutics, Inc.COM1,550,184$28.1M5.6%+338,088+27.9%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,465,151$27.4M5.5%+110,000+8.1%AddedHistory
PNTPOINT Biopharma Global Inc.COM3,000,000$27.2M5.4%−383,029−11.3%ReducedHistory
ZURAZura Bio LtdCLASS A ORD SHS3,295,000$27.0M5.4%+3,295,000NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM968,795$20.9M4.2%+185,000+23.6%AddedHistory
XENEXenon Pharmaceuticals Inc.COM530,000$20.4M4.1%−288,505−35.2%ReducedHistory
ACRSAclaris Therapeutics, Inc.COM1,941,581$20.1M4.0%+750,000+62.9%AddedHistory
CYTKCytokinetics IncCOM NEW600,000$19.6M3.9%+100,000+20.0%AddedHistory
ANABAnaptysbio, IncCOM894,333$18.2M3.6%+90,000+11.2%AddedHistory
IMCRImmunocore Holdings plcADS297,082$17.8M3.6%+41,715+16.3%AddedHistory
EOLSEvolus, Inc.COM2,434,048$17.7M3.5%+241,232+11.0%AddedHistory
JBIOJade Biosciences, Inc.COM932,158$16.0M3.2%+176,538+23.4%AddedHistory
SRPTSarepta Therapeutics, Inc.COM123,600$14.2M2.8%+123,600NewHistory
ALKSAlkermes plc.SHS411,453$12.9M2.6%+411,453NewHistory
RYTMRhythm Pharmaceuticals, Inc.COM772,000$12.7M2.6%+674,456+691.4%AddedHistory
OPTNOptiNose, Inc.COM8,839,939$10.9M2.2%+945,203+12.0%AddedHistory
VKTXViking Therapeutics, Inc.COM598,550$9.70M1.9%−401,450−40.1%ReducedHistory
MLYSMineralys Therapeutics, Inc.COM546,059$9.31M1.9%−74,267−12.0%ReducedHistory
FOLDAmicus Therapeutics, Inc.COM701,392$8.81M1.8%+321,392+84.6%AddedHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS2,268,057$8.64M1.7%−885,149−28.1%Reduced–
OKUROnKure Therapeutics, Inc.COM1,083,317$7.11M1.4%+962,453+796.3%AddedHistory
ICPTIntercept Pharmaceuticals, Inc.COM601,322$6.65M1.3%+601,322NewHistory
FDMT4D Molecular Therapeutics, Inc.COM350,000$6.32M1.3%+350,000NewHistory
GBIOGeneration Bio Co.COM1,022,537$5.62M1.1%00.0%UnchangedHistory
HRTXHeron Therapeutics, Inc.COM4,737,368$5.50M1.1%−1,080,000−18.6%ReducedHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,051,267$5.06M1.0%00.0%UnchangedHistory
IGMSIGM Biosciences, Inc.COM500,000$4.62M0.9%+500,000NewHistory
MCRBSeres Therapeutics, Inc.COM938,067$4.49M0.9%+938,067NewHistory
DTILPrecision Biosciences IncCOM7,469,736$3.93M0.8%−630,063−7.8%ReducedHistory
SLDBSolid Biosciences Inc.COM NEW584,458$3.06M0.6%+374,053+177.8%AddedHistory
TRMLTourmaline Bio, Inc.COM666,033$2.02M0.4%+666,033NewHistory
ACLXArcellx, Inc.COMMON STOCK37,500$1.19M0.2%−219,506−85.4%ReducedHistory
TVTXTravere Therapeutics, Inc.COM60,000$921.6K0.2%−943,000−94.0%ReducedHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Great Point Partners LLC in Q2 2023
SecurityClassPutsCalls
APLSApellis Pharmaceuticals, Inc.COM$8.63M–
ACRSAclaris Therapeutics, Inc.COM$2.64M–
MRSNMersana Therapeutics, Inc.COM–$230.3K
XENEXenon Pharmaceuticals Inc.COM$104.0K–

Sold out since Q1 2023 (14)

Positions held at the end of Q1 2023 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q1 2023
SecurityClassShares in Q1 2023Value in Q1 2023% of portfolio in Q1 2023History
JAZZJazz Pharmaceuticals plcSHS USD149,500$21.9M4.3%History
ISEEIVERIC bio, Inc.COM694,009$16.9M3.3%History
KALVKalVista Pharmaceuticals, Inc.COM1,600,545$12.6M2.5%History
RLAYRelay Therapeutics, Inc.COM658,127$10.8M2.1%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD278,334$5.95M1.2%History
CBAYCymaBay Therapeutics, Inc.COM507,500$4.43M0.9%History
LRMRLarimar Therapeutics, Inc.COM900,000$4.08M0.8%History
ITCIIntra-Cellular Therapies, Inc.COM70,371$3.81M0.8%History
ETNB89bio, Inc.COM250,000$3.81M0.8%History
ZVRAZevra Therapeutics, Inc.COM NEW347,824$1.91M0.4%History
DAWNDay One Biopharmaceuticals, Inc.Stock141,526$1.89M0.4%History
PRAXPraxis Precision Medicines, Inc.COM2,032,550$1.64M0.3%History
AVTXAvalo Therapeutics, Inc.COM NEW474,639$830.6K0.2%History
URGNUroGen Pharma Ltd.COM39,222$362.4K0.1%History