Skip to main content
Livermore
Livermore
ZHEN

Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q1 2023

Holdings as of Mar 31, 2023, filed May 15, 2023. Long positions only; changes compare share counts with Q4 2022.

Institution overview
Positions
42
+2 vs. Q4 2022
Portfolio value
$506.0M
+$22.3M (+4.6%) vs. Q4 2022
Filed
May 15, 2023
SEC
Holdings of Great Point Partners LLC in Q1 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
PLRXPliant Therapeutics, Inc.COM1,212,096$32.2M6.4%−110,774−8.4%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM818,505$29.3M5.8%−31,495−3.7%ReducedHistory
ALPNAlpine Immune Sciences, Inc.COM3,740,761$28.9M5.7%+103,043+2.8%AddedHistory
RAREUltragenyx Pharmaceutical Inc.COM677,426$27.2M5.4%+335,126+97.9%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,355,151$24.9M4.9%−81,418−5.7%ReducedHistory
PCVXVaxcyte, Inc.COM659,211$24.7M4.9%−140,789−17.6%ReducedHistory
PNTPOINT Biopharma Global Inc.COM3,383,029$24.6M4.9%+841,250+33.1%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM783,795$23.0M4.5%+593,795+312.5%AddedHistory
TVTXTravere Therapeutics, Inc.COM1,003,000$22.6M4.5%+528,000+111.2%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD149,500$21.9M4.3%−10,500−6.6%ReducedHistory
EOLSEvolus, Inc.COM2,192,816$18.6M3.7%+2,002,487+1,052.1%AddedHistory
CYTKCytokinetics IncCOM NEW500,000$17.6M3.5%+500,000NewHistory
ANABAnaptysbio, IncCOM804,333$17.5M3.5%+789,333+5,262.2%AddedHistory
ISEEIVERIC bio, Inc.COM694,009$16.9M3.3%−130,991−15.9%ReducedHistory
VKTXViking Therapeutics, Inc.COM1,000,000$16.6M3.3%−295,034−22.8%ReducedHistory
JBIOJade Biosciences, Inc.COM755,620$15.2M3.0%+377,098+99.6%AddedHistory
OPTNOptiNose, Inc.COM7,894,736$15.2M3.0%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS255,367$12.6M2.5%+255,367NewHistory
KALVKalVista Pharmaceuticals, Inc.COM1,600,545$12.6M2.5%+544,744+51.6%AddedHistory
RLAYRelay Therapeutics, Inc.COM658,127$10.8M2.1%+658,127NewHistory
MLYSMineralys Therapeutics, Inc.COM620,326$9.71M1.9%+620,326NewHistory
ACRSAclaris Therapeutics, Inc.COM1,191,581$9.64M1.9%+172,299+16.9%AddedHistory
HRTXHeron Therapeutics, Inc.COM5,817,368$8.78M1.7%−542,793−8.5%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK257,006$7.92M1.6%+257,006NewHistory
DTILPrecision Biosciences IncCOM8,099,799$6.10M1.2%+4,298,494+113.1%AddedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD278,334$5.95M1.2%−364,232−56.7%ReducedHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS3,153,206$5.86M1.2%+1,190,807+60.7%Added–
CBAYCymaBay Therapeutics, Inc.COM507,500$4.43M0.9%−1,042,500−67.3%ReducedHistory
GBIOGeneration Bio Co.COM1,022,537$4.40M0.9%00.0%UnchangedHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,051,267$4.27M0.8%−65,314−5.8%ReducedHistory
FOLDAmicus Therapeutics, Inc.COM380,000$4.21M0.8%+380,000NewHistory
LRMRLarimar Therapeutics, Inc.COM900,000$4.08M0.8%−373,635−29.3%ReducedHistory
ITCIIntra-Cellular Therapies, Inc.COM70,371$3.81M0.8%+70,371NewHistory
ETNB89bio, Inc.COM250,000$3.81M0.8%+250,000NewHistory
ZVRAZevra Therapeutics, Inc.COM NEW347,824$1.91M0.4%+347,824NewHistory
DAWNDay One Biopharmaceuticals, Inc.Stock141,526$1.89M0.4%−402,925−74.0%ReducedHistory
RYTMRhythm Pharmaceuticals, Inc.COM97,544$1.74M0.3%+97,544NewHistory
PRAXPraxis Precision Medicines, Inc.COM2,032,550$1.64M0.3%+2,032,550NewHistory
SLDBSolid Biosciences Inc.COM NEW210,405$997.3K0.2%+210,405NewHistory
AVTXAvalo Therapeutics, Inc.COM NEW474,639$830.6K0.2%+474,639NewHistory
OKUROnKure Therapeutics, Inc.COM120,864$722.8K0.1%+120,864NewHistory
URGNUroGen Pharma Ltd.COM39,222$362.4K0.1%−520,778−93.0%ReducedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Great Point Partners LLC in Q1 2023
SecurityClassPutsCalls
ACRSAclaris Therapeutics, Inc.COM–$2.02M
VKTXViking Therapeutics, Inc.COM$1.33M–

Sold out since Q4 2022 (12)

Positions held at the end of Q4 2022 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q4 2022
SecurityClassShares in Q4 2022Value in Q4 2022% of portfolio in Q4 2022History
SGENSeagen Inc.COM160,500$20.6M4.3%History
VTYXVentyx Biosciences, Inc.COM400,695$13.1M2.7%History
CINCCinCor Pharma, Inc.COM1,019,153$12.5M2.6%History
PTCTPTC Therapeutics, Inc.COM302,135$11.5M2.4%History
SRPTSarepta Therapeutics, Inc.COM73,000$9.46M2.0%History
ERASErasca, Inc.COM1,538,461$6.63M1.4%History
ICPTIntercept Pharmaceuticals, Inc.COM528,850$6.54M1.4%History
MRTXMirati Therapeutics, Inc.COM133,000$6.03M1.2%History
VERVVerve Therapeutics, Inc.COM300,000$5.80M1.2%History
ALBOAlbireo Pharma, Inc.COM267,283$5.78M1.2%History
ALKSAlkermes plc.SHS46,185$1.21M0.2%History
IMUXImmunic, Inc.COM632,184$885.1K0.2%History