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Livermore
ZHEN

Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q3 2023

Holdings as of Sep 30, 2023, filed Nov 14, 2023. Long positions only; changes compare share counts with Q2 2023.

Institution overview
Positions
39
+3 vs. Q2 2023
Portfolio value
$531.6M
+$32.4M (+6.5%) vs. Q2 2023
Filed
Nov 14, 2023
SEC
Holdings of Great Point Partners LLC in Q3 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
URGNUroGen Pharma Ltd.COM2,620,545$36.7M6.9%+2,620,545NewHistory
ALPNAlpine Immune Sciences, Inc.COM3,078,633$35.3M6.6%−285,055−8.5%ReducedHistory
PLRXPliant Therapeutics, Inc.COM1,755,184$30.4M5.7%+205,000+13.2%AddedHistory
PCVXVaxcyte, Inc.COM531,211$27.1M5.1%−58,000−9.8%ReducedHistory
RAREUltragenyx Pharmaceutical Inc.COM727,426$25.9M4.9%+50,000+7.4%AddedHistory
ALKSAlkermes plc.SHS875,044$24.5M4.6%+463,591+112.7%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,458,070$24.2M4.6%−7,081−0.5%ReducedHistory
ZURAZura Bio LtdCLASS A ORD SHS3,295,000$21.7M4.1%00.0%UnchangedHistory
SRPTSarepta Therapeutics, Inc.COM165,200$20.0M3.8%+41,600+33.7%AddedHistory
EOLSEvolus, Inc.COM2,186,934$20.0M3.8%−247,114−10.2%ReducedHistory
PNTPOINT Biopharma Global Inc.COM2,909,960$19.4M3.7%−90,040−3.0%ReducedHistory
CYTKCytokinetics IncCOM NEW600,000$17.7M3.3%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM500,001$17.1M3.2%−29,999−5.7%ReducedHistory
ANABAnaptysbio, IncCOM894,333$16.1M3.0%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS290,917$15.1M2.8%−6,165−2.1%ReducedHistory
JBIOJade Biosciences, Inc.COM1,091,233$14.8M2.8%+159,075+17.1%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM225,000$11.7M2.2%+225,000NewHistory
ACRSAclaris Therapeutics, Inc.COM1,691,768$11.6M2.2%−249,813−12.9%ReducedHistory
PTCTPTC Therapeutics, Inc.COM500,000$11.2M2.1%+500,000NewHistory
REPLReplimune Group, Inc.COM638,495$10.9M2.1%+638,495NewHistory
OPTNOptiNose, Inc.COM8,839,939$10.9M2.0%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM857,000$10.4M2.0%+155,608+22.2%AddedHistory
ACLXArcellx, Inc.COMMON STOCK287,500$10.3M1.9%+250,000+666.7%AddedHistory
KRTXKaruna Therapeutics, Inc.COM60,500$10.2M1.9%+60,500NewHistory
AKROAkero Therapeutics, Inc.COM198,500$10.0M1.9%+198,500NewHistory
INSMINSMED IncCOM PAR $.01394,872$9.97M1.9%+394,872NewHistory
OKUROnKure Therapeutics, Inc.COM1,167,061$8.89M1.7%+83,744+7.7%AddedHistory
APGEApogee Therapeutics, Inc.COM400,000$8.52M1.6%+400,000NewHistory
GOSSGossamer Bio, Inc.COM6,230,272$5.19M1.0%+6,230,272NewHistory
IGMSIGM Biosciences, Inc.COM615,317$5.14M1.0%+115,317+23.1%AddedHistory
HRTXHeron Therapeutics, Inc.COM4,737,368$4.88M0.9%00.0%UnchangedHistory
CERECerevel Therapeutics Holdings, Inc.COM215,000$4.69M0.9%+215,000NewHistory
ABOSAcumen Pharmaceuticals, Inc.COM1,074,101$4.46M0.8%+22,834+2.2%AddedHistory
GBIOGeneration Bio Co.COM1,022,537$3.88M0.7%00.0%UnchangedHistory
MRTXMirati Therapeutics, Inc.COM86,302$3.76M0.7%+86,302NewHistory
TERNTerns Pharmaceuticals, Inc.COM645,899$3.25M0.6%+645,899NewHistory
TRMLTourmaline Bio, Inc.COM1,000,000$2.81M0.5%+333,967+50.1%AddedHistory
Gracell Biotechnologies Inc38406L103SPONSORED ADS579,667$1.67M0.3%−1,688,390−74.4%Reduced–
SLDBSolid Biosciences Inc.COM NEW450,403$1.14M0.2%−134,055−22.9%ReducedHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Great Point Partners LLC in Q3 2023
SecurityClassPutsCalls
SRPTSarepta Therapeutics, Inc.COM$11.5M–
ACRSAclaris Therapeutics, Inc.COM–$4.79M
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS–$1.12M

Sold out since Q2 2023 (9)

Positions held at the end of Q2 2023 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q2 2023
SecurityClassShares in Q2 2023Value in Q2 2023% of portfolio in Q2 2023History
AMLXAmylyx Pharmaceuticals, Inc.COM968,795$20.9M4.2%History
RYTMRhythm Pharmaceuticals, Inc.COM772,000$12.7M2.6%History
VKTXViking Therapeutics, Inc.COM598,550$9.70M1.9%History
MLYSMineralys Therapeutics, Inc.COM546,059$9.31M1.9%History
ICPTIntercept Pharmaceuticals, Inc.COM601,322$6.65M1.3%History
FDMT4D Molecular Therapeutics, Inc.COM350,000$6.32M1.3%History
MCRBSeres Therapeutics, Inc.COM938,067$4.49M0.9%History
DTILPrecision Biosciences IncCOM7,469,736$3.93M0.8%History
TVTXTravere Therapeutics, Inc.COM60,000$921.6K0.2%History