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Great Point Partners LLC

SEC CIK
0001281446
Latest filing
Aug 14, 2026

Holdings in Q4 2023

Holdings as of Dec 31, 2023, filed Feb 14, 2024. Long positions only; changes compare share counts with Q3 2023.

Institution overview
Positions
34
−5 vs. Q3 2023
Portfolio value
$586.7M
+$55.1M (+10.4%) vs. Q3 2023
Filed
Feb 14, 2024
SEC
Holdings of Great Point Partners LLC in Q4 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
ALPNAlpine Immune Sciences, Inc.COM3,703,433$70.6M12.0%+624,800+20.3%AddedHistory
CYTKCytokinetics IncCOM NEW500,000$41.7M7.1%−100,000−16.7%ReducedHistory
URGNUroGen Pharma Ltd.COM2,620,545$39.3M6.7%00.0%UnchangedHistory
PLRXPliant Therapeutics, Inc.COM1,823,184$33.0M5.6%+68,000+3.9%AddedHistory
RAREUltragenyx Pharmaceutical Inc.COM648,000$31.0M5.3%−79,426−10.9%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM600,000$27.6M4.7%+99,999+20.0%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,099,753$27.3M4.7%−358,317−24.6%ReducedHistory
ALKSAlkermes plc.SHS875,044$24.3M4.1%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM1,037,690$23.5M4.0%−53,543−4.9%ReducedHistory
PCVXVaxcyte, Inc.COM360,000$22.6M3.9%−171,211−32.2%ReducedHistory
EOLSEvolus, Inc.COM2,000,000$21.1M3.6%−186,934−8.5%ReducedHistory
ANABAnaptysbio, IncCOM976,981$20.9M3.6%+82,648+9.2%AddedHistory
IMCRImmunocore Holdings plcADS293,000$20.0M3.4%+2,083+0.7%AddedHistory
NGNENeurogene Inc.COM994,229$19.3M3.3%+994,229NewHistory
FOLDAmicus Therapeutics, Inc.COM1,280,500$18.2M3.1%+423,500+49.4%AddedHistory
TRMLTourmaline Bio, Inc.COM672,885$17.6M3.0%+672,885NewHistory
ABVXAbivax S.A.SPONSORED ADS1,550,000$16.6M2.8%+1,550,000NewHistory
ZURAZura Bio LtdCLASS A ORD SHS3,295,000$15.4M2.6%00.0%UnchangedHistory
OPTNOptiNose, Inc.COM8,839,939$11.4M1.9%00.0%UnchangedHistory
APGEApogee Therapeutics, Inc.COM400,000$11.2M1.9%00.0%UnchangedHistory
ARVNArvinas, Inc.COM234,082$9.63M1.6%+234,082NewHistory
KRTXKaruna Therapeutics, Inc.COM30,250$9.57M1.6%−30,250−50.0%ReducedHistory
VTGNVistagen Therapeutics, Inc.COM1,858,735$9.55M1.6%+1,858,735NewHistory
TERNTerns Pharmaceuticals, Inc.COM1,309,975$8.50M1.4%+664,076+102.8%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM110,607$7.92M1.4%−114,393−50.8%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM80,000$7.71M1.3%−85,200−51.6%ReducedHistory
INSMINSMED IncCOM PAR $.01225,912$7.00M1.2%−168,960−42.8%ReducedHistory
PBYIPuma Biotechnology, Inc.COM1,093,273$4.73M0.8%+1,093,273NewHistory
OCULOcular Therapeutix, IncCOM700,000$3.12M0.5%+700,000NewHistory
SYRESpyre Therapeutics, Inc.COM NEW125,000$2.69M0.5%+125,000NewHistory
ACLXArcellx, Inc.COMMON STOCK48,264$2.68M0.5%−239,236−83.2%ReducedHistory
MRUSMerus N.V.COM20,000$550.0K0.1%+20,000NewHistory
AXSMAxsome Therapeutics, Inc.COM4,963$395.0K0.1%+4,963NewHistory
MURAMural Oncology plcORD SHS11,509$68.1K<0.1%+11,509NewHistory

Sold out since Q3 2023 (16)

Positions held at the end of Q3 2023 that are gone from this filing.

Positions of Great Point Partners LLC sold out since Q3 2023
SecurityClassShares in Q3 2023Value in Q3 2023% of portfolio in Q3 2023History
PNTPOINT Biopharma Global Inc.COM2,909,960$19.4M3.7%History
ACRSAclaris Therapeutics, Inc.COM1,691,768$11.6M2.2%History
PTCTPTC Therapeutics, Inc.COM500,000$11.2M2.1%History
REPLReplimune Group, Inc.COM638,495$10.9M2.1%History
AKROAkero Therapeutics, Inc.COM198,500$10.0M1.9%History
OKUROnKure Therapeutics, Inc.COM1,167,061$8.89M1.7%History
GOSSGossamer Bio, Inc.COM6,230,272$5.19M1.0%History
IGMSIGM Biosciences, Inc.COM615,317$5.14M1.0%History
HRTXHeron Therapeutics, Inc.COM4,737,368$4.88M0.9%History
CERECerevel Therapeutics Holdings, Inc.COM215,000$4.69M0.9%History
ABOSAcumen Pharmaceuticals, Inc.COM1,074,101$4.46M0.8%History
GBIOGeneration Bio Co.COM1,022,537$3.88M0.7%History
MRTXMirati Therapeutics, Inc.COM86,302$3.76M0.7%History
TRMLTourmaline Bio, Inc.COM1,000,000$2.81M0.5%History
Gracell Biotechnologies Inc38406L103SPONSORED ADS579,667$1.67M0.3%–
SLDBSolid Biosciences Inc.COM NEW450,403$1.14M0.2%History