Skip to main content
Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q4 2021

Holdings as of Dec 31, 2021, filed May 4, 2022. Long positions only; changes compare share counts with Q3 2021.

Institution overview
Positions
145
+7 vs. Q3 2021
Portfolio value
$6.47B
−$388.8M (−5.7%) vs. Q3 2021
Filed
May 4, 2022
AmendedSEC
Holdings of Perceptive Advisors LLC in Q4 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
LEGNLegend Biotech CorpSPONSORED ADS189,100$8.81M0.1%+189,100NewHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$8.58M0.1%00.0%UnchangedHistory
EQRXEQRx, Inc.COM1,250,000$8.53M0.1%+1,250,000NewHistory
MDGLMadrigal Pharmaceuticals, Inc.COM86,400$7.32M0.1%+86,400NewHistory
ATXSAstria Therapeutics, Inc.COM1,281,197$6.91M0.1%−678,455−34.6%ReducedHistory
SGHTSight Sciences, Inc.COM390,000$6.85M0.1%00.0%UnchangedHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$6.77M0.1%00.0%UnchangedHistory
PNTPOINT Biopharma Global Inc.COM1,193,995$6.69M0.1%−48,884−3.9%ReducedHistory
AORTArtivion, Inc.COM326,318$6.64M0.1%+326,318NewHistory
ACCDAccolade, Inc.COM228,774$6.03M0.1%−51,000−18.2%ReducedHistory
ZYZymergen Inc.COM883,332$5.91M0.1%00.0%UnchangedHistory
PEARPear Therapeutics, Inc.CLASS A COM926,232$5.74M0.1%+926,232NewHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$5.58M0.1%00.0%UnchangedHistory
PRVBProvention Bio, Inc.COM948,481$5.33M0.1%00.0%UnchangedHistory
ONCROncorus, Inc.COM999,812$5.27M0.1%−99,998−9.1%ReducedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$5.20M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$5.15M0.1%+781,615NewHistory
FUSNFusion Pharmaceuticals Inc.COM1,227,017$5.12M0.1%−27,590−2.2%ReducedHistory
PRTAProthena Corp Public Ltd CoSHS100,000$4.94M0.1%00.0%UnchangedHistory
DALSDA32 Life Science Tech Acquisition Corp.CLASS A COM500,000$4.91M0.1%00.0%UnchangedHistory
TBIOTelesis Bio Inc.COM425,000$4.59M0.1%00.0%UnchangedHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS450,000$4.54M0.1%00.0%UnchangedHistory
DRIODarioHealth Corp.COM NEW327,869$4.25M0.1%00.0%UnchangedHistory
NEPTFNeptune Wellness Solutions Inc.COM10,055,521$4.12M0.1%00.0%UnchangedHistory
RPIDRapid Micro Biosystems, Inc.CLASS A COM385,693$4.10M0.1%+35,693+10.2%AddedHistory
SONXSonendo, Inc.COM668,505$3.85M0.1%+668,505NewHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$3.78M0.1%00.0%Unchanged–
AXSMAxsome Therapeutics, Inc.COM80,420$3.04M<0.1%00.0%UnchangedHistory
PMVPPMV Pharmaceuticals, Inc.COM125,000$2.89M<0.1%−176,714−58.6%ReducedHistory
TARAProtara Therapeutics, Inc.COM STK421,641$2.85M<0.1%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM413,446$2.66M<0.1%−86,554−17.3%ReducedHistory
YARWYarrow Bioscience, Inc.COM2,178,022$2.22M<0.1%−152,449−6.5%ReducedHistory
NVRONevro CorpCOM22,946$1.86M<0.1%−237,026−91.2%ReducedHistory
RACEFerrari N.V.COM6,200$1.60M<0.1%00.0%UnchangedHistory
ITOSiTeos Therapeutics, Inc.COM20,000$931.0K<0.1%+20,000NewHistory
MOTSMotus GI Holdings, Inc.COM1,800,542$841.0K<0.1%00.0%UnchangedHistory
EIGREiger BioPharmaceuticals, Inc.COM139,890$726.0K<0.1%00.0%UnchangedHistory
Rockley Photonics Holdings LG7614L117*W EXP 08/11/202500,000$605.0K<0.1%00.0%Unchanged–
UTRSMinerva Surgical IncCOM87,768$451.0K<0.1%+87,768NewHistory
PHVSPharvaris N.V.COM27,000$389.0K<0.1%00.0%UnchangedHistory
SLGCWSomaLogic, Inc.*W EXP 03/01/202110,000$367.0K<0.1%00.0%UnchangedHistory
Butterfly Network, Inc.124155110*W EXP 05/27/202233,333$296.0K<0.1%00.0%Unchanged–
EQRx, Inc.26886C115*W EXP 12/17/202250,000$266.0K<0.1%+250,000New–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$192.0K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$84.0K<0.1%00.0%Unchanged–

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q4 2021
SecurityClassPutsCalls
FLNAFilana Therapeutics, Inc.COM$13.1M–
DCPHDeciphera Pharmaceuticals, Inc.COM–$1.95M

Sold out since Q3 2021 (15)

Positions held at the end of Q3 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q3 2021
SecurityClassShares in Q3 2021Value in Q3 2021% of portfolio in Q3 2021History
AVIRAtea Pharmaceuticals, Inc.COM2,259,224$79.2M1.2%History
BEAMBeam Therapeutics Inc.COM537,635$46.8M0.7%History
DBVTDBV Technologies S.A.SPONSORED ADR7,695,505$37.7M0.5%History
Avidity Biosciences, Inc.05370A108COM885,818$21.8M0.3%–
NTRANatera, Inc.COM160,000$17.8M0.3%History
CM Life Sciences III Inc125841205UNIT 04/30/20281,250,000$12.8M0.2%–
PODDInsulet CorpStock44,522$12.7M0.2%History
FDMT4D Molecular Therapeutics, Inc.COM375,256$10.1M0.1%History
TSHATaysha Gene Therapies, Inc.COM SHS320,440$5.97M0.1%History
PSTXPoseida Therapeutics, Inc.COM787,745$5.74M0.1%History
ATECAlphatec Holdings, Inc.COM NEW430,900$5.25M0.1%History
RGNXREGENXBIO Inc.COM89,283$3.74M0.1%History
SNCEScience 37 Holdings, Inc.COM300,000$2.94M<0.1%History
IMGOImago BioSciences, Inc.COM125,000$2.50M<0.1%History
KRROKorro Bio, Inc.COM222,222$1.57M<0.1%History