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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q1 2022

Holdings as of Mar 31, 2022, filed May 16, 2022. Long positions only; changes compare share counts with Q4 2021.

Institution overview
Positions
135
−10 vs. Q4 2021
Portfolio value
$4.81B
−$1.66B (−25.6%) vs. Q4 2021
Filed
May 16, 2022
SEC
Holdings of Perceptive Advisors LLC in Q1 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$474.1M9.8%–New–
FOLDAmicus Therapeutics, Inc.COM27,555,845$261.0M5.4%+996,402+3.8%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM4,527,993$255.6M5.3%−321,919−6.6%ReducedHistory
LIANYLianBioSPONSORED ADS56,319,960$208.9M4.3%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM12,201,261$203.2M4.2%+2,073,320+20.5%AddedHistory
MRTXMirati Therapeutics, Inc.COM2,380,710$195.7M4.1%−903,073−27.5%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM5,086,727$178.1M3.7%00.0%UnchangedHistory
HZNPHorizon Therapeutics Public Ltd CoSHS1,357,903$142.9M3.0%−380,237−21.9%ReducedHistory
GBTGlobal Blood Therapeutics, Inc.COM3,892,493$134.8M2.8%+442,578+12.8%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM5,163,517$113.3M2.4%00.0%UnchangedHistory
MGTXMeiraGTx Holdings plcCOM6,948,277$96.2M2.0%00.0%UnchangedHistory
RXDXPrometheus Biosciences, Inc.COM2,440,582$92.2M1.9%−732,203−23.1%ReducedHistory
Collegium Pharmaceutical, Inc19459JAA2NOTE 2.625% 2/1–$89.5M1.9%–––
ISEEIVERIC bio, Inc.COM5,225,415$87.9M1.8%−1,254,585−19.4%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$86.9M1.8%00.0%UnchangedHistory
OMOutset Medical, Inc.COM1,883,399$85.5M1.8%+20,002+1.1%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM1,481,700$75.3M1.6%+30,000+2.1%AddedHistory
XENEXenon Pharmaceuticals Inc.COM2,411,447$73.7M1.5%00.0%UnchangedHistory
ALBOAlbireo Pharma, Inc.COM2,360,139$70.4M1.5%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM2,799,962$61.6M1.3%−127,603−4.4%ReducedHistory
CHRSCoherus Oncology, Inc.COM4,695,848$60.6M1.3%−711,950−13.2%ReducedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$58.2M1.2%00.0%UnchangedHistory
Bellus Health Inc New07987C204COM NEW8,136,630$56.0M1.2%+491,396+6.4%Added–
PRCTPROCEPT BioRobotics CorpCOM1,488,284$52.1M1.1%+159,999+12.0%AddedHistory
CCCCC4 Therapeutics, Inc.COM STK2,082,723$50.5M1.0%−126,190−5.7%ReducedHistory
TVTXTravere Therapeutics, Inc.COM1,845,555$47.6M1.0%00.0%UnchangedHistory
LONALeonaBio, Inc.COM3,425,916$46.3M1.0%00.0%UnchangedHistory
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$44.6M0.9%–––
ALDXAldeyra Therapeutics, Inc.COM9,903,879$44.0M0.9%00.0%UnchangedHistory
ChemoCentryx, Inc.16383L106COM1,655,079$41.5M0.9%+239,633+16.9%Added–
CINCCinCor Pharma, Inc.COM2,319,117$40.7M0.8%+2,319,117NewHistory
INBXInhibrx Biosciences, Inc.COM1,781,235$39.7M0.8%+437,745+32.6%AddedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$39.5M0.8%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM3,839,380$39.0M0.8%−3,289,375−46.1%ReducedHistory
NBIXNeurocrine Biosciences IncStock395,639$37.1M0.8%−87,368−18.1%ReducedHistory
ZYMEZymeworks Inc.COM5,325,615$34.9M0.7%+1,645,770+44.7%AddedHistory
NVRONevro CorpCOM477,037$34.5M0.7%+454,091+1,979.0%AddedHistory
PENPenumbra IncCOM143,591$31.9M0.7%+143,591NewHistory
MORFMorphic Holding, Inc.COM767,327$30.8M0.6%−69,194−8.3%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM450,374$30.4M0.6%+44,833+11.1%AddedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM180,079$29.4M0.6%+180,079NewHistory
VRCAVerrica Pharmaceuticals Inc.COM3,610,412$29.3M0.6%00.0%UnchangedHistory
DICEDICE Therapeutics, Inc.COM1,515,361$29.0M0.6%+810,476+115.0%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM278,286$27.3M0.6%+191,886+222.1%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,678,090$26.6M0.6%−281,035−14.3%ReducedHistory
VRDNViridian Therapeutics, Inc.COM1,423,053$26.3M0.5%00.0%UnchangedHistory
NUVLNuvalent, Inc.COM1,751,601$24.3M0.5%+1,001,601+133.5%AddedHistory
COGTCogent Biosciences, Inc.COM3,188,750$23.9M0.5%00.0%UnchangedHistory
CMAXCareMax, Inc.COM CL A3,186,663$23.8M0.5%−362,862−10.2%ReducedHistory
ZNTLZentalis Pharmaceuticals, Inc.COM501,509$23.1M0.5%+70,965+16.5%AddedHistory
OMICSingular Genomics Systems, Inc.COM3,655,207$23.1M0.5%+321,383+9.6%AddedHistory
LEGNLegend Biotech CorpSPONSORED ADS616,141$22.4M0.5%+427,041+225.8%AddedHistory
LABPLandos Biopharma, Inc.COM14,869,915$21.9M0.5%00.0%UnchangedHistory
ADMAAdma Biologics, Inc.COM11,933,387$21.8M0.5%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$21.8M0.5%00.0%UnchangedHistory
AXNXAxonics, Inc.COM341,211$21.4M0.4%+341,211NewHistory
VERUVeru Inc.COM4,361,998$21.1M0.4%−89,344−2.0%ReducedHistory
IMTXImmatics N.V.SHS2,500,000$20.0M0.4%00.0%UnchangedHistory
QTNTQuotient LtdSHS16,200,818$19.4M0.4%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM1,474,107$18.9M0.4%+1,474,107NewHistory
TMCITreace Medical Concepts, Inc.COM971,192$18.4M0.4%−8,994−0.9%ReducedHistory
KRONKronos Bio, Inc.COM2,421,142$17.5M0.4%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM13,412,552$16.1M0.3%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS3,044,303$15.2M0.3%+176,793+6.2%AddedHistory
ISOIsoPlexis CorpCOM4,095,498$14.0M0.3%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM7,951,448$13.9M0.3%−525,048−6.2%ReducedHistory
MGNXMacrogenics IncCOM1,559,789$13.7M0.3%−105,454−6.3%ReducedHistory
LUNGPulmonx CorpCOM537,779$13.3M0.3%−224,525−29.5%ReducedHistory
AORTArtivion, Inc.COM615,703$13.2M0.3%+289,385+88.7%AddedHistory
LYRALyra Therapeutics, Inc.COM3,222,560$13.0M0.3%00.0%UnchangedHistory
HCATHealth Catalyst, Inc.COM493,662$12.9M0.3%+39,658+8.7%AddedHistory
RCUSArcus Biosciences, Inc.COM405,000$12.8M0.3%+405,000NewHistory
Rain Oncology Inc.75082Q105COM2,483,619$12.6M0.3%00.0%Unchanged–
SLGCSomaLogic, Inc.CLASS A COM1,500,000$12.0M0.2%00.0%UnchangedHistory
ATNXAthenex, Inc.COM13,532,467$11.2M0.2%00.0%UnchangedHistory
Nanostring Technologies Inc63009RAD1NOTE 2.625% 5/0–$11.0M0.2%–––
HLTHCue Health Inc.COM1,580,607$10.2M0.2%00.0%UnchangedHistory
ABSIAbsci CorpCOM1,190,952$10.0M0.2%−220,824−15.6%ReducedHistory
BCLS Acquisition CorpG0904B105COM CL A1,000,000$9.87M0.2%00.0%Unchanged–
Summit Healthcre Acquistn CoG8566R128UNIT 06/03/20261,000,000$9.78M0.2%00.0%Unchanged–
RACBResearch Alliance Corp. IICOM CL A1,000,000$9.76M0.2%00.0%UnchangedHistory
ICVXIcosavax, Inc.COM1,379,137$9.71M0.2%−527,411−27.7%ReducedHistory
FUSNFusion Pharmaceuticals Inc.COM1,227,017$9.53M0.2%00.0%UnchangedHistory
PNTPOINT Biopharma Global Inc.COM1,193,995$9.52M0.2%00.0%UnchangedHistory
NUVBNuvation Bio Inc.COM CL A1,769,701$9.31M0.2%−1,151,122−39.4%ReducedHistory
ATXSAstria Therapeutics, Inc.COM1,281,197$8.60M0.2%00.0%UnchangedHistory
EVHEvolent Health, Inc.CL A250,000$8.07M0.2%+250,000NewHistory
SNCEScience 37 Holdings, Inc.COM1,500,000$8.03M0.2%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$7.88M0.2%00.0%UnchangedHistory
WGSGeneDx Holdings Corp.COMMON STOCK2,500,000$7.67M0.2%00.0%UnchangedHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$7.25M0.2%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$6.96M0.1%00.0%UnchangedHistory
ACADAcadia Pharmaceuticals IncCOM284,853$6.90M0.1%−1,299,199−82.0%ReducedHistory
ACRSAclaris Therapeutics, Inc.COM383,239$6.61M0.1%−397,997−50.9%ReducedHistory
PYXSPyxis Oncology, Inc.COMMON STOCK1,528,812$6.18M0.1%−415,302−21.4%ReducedHistory
ACCDAccolade, Inc.COM330,682$5.81M0.1%+101,908+44.5%AddedHistory
PRVBProvention Bio, Inc.COM791,549$5.79M0.1%−156,932−16.5%ReducedHistory
PRVAPrivia Health Group, Inc.COM213,423$5.71M0.1%+213,423NewHistory
MRUSMerus N.V.COM209,046$5.53M0.1%−140,954−40.3%ReducedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock556,047$5.52M0.1%00.0%UnchangedHistory

Sold out since Q4 2021 (24)

Positions held at the end of Q4 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q4 2021
SecurityClassShares in Q4 2021Value in Q4 2021% of portfolio in Q4 2021History
Retrophin Inc761299AB2NOTE 2.500% 9/1–$484.7M7.5%–
BMRNBiomarin Pharmaceutical IncCOM1,180,000$104.3M1.6%History
Nevro Corp64157FAC7NOTE 2.750% 4/0–$101.5M1.6%–
ARNAArena Pharmaceuticals IncCOM NEW500,000$46.5M0.7%History
KODKodiak Sciences Inc.COM520,152$44.1M0.7%History
UTHRUnited Therapeutics CorpCOM94,064$20.3M0.3%History
VTRSViatris IncStock1,004,419$13.6M0.2%History
BCABBioAtla, Inc.COM661,200$13.0M0.2%History
IMCRImmunocore Holdings plcADS360,000$12.3M0.2%History
BIIBBiogen Inc.COM48,600$11.7M0.2%History
HRMYHarmony Biosciences Holdings, Inc.COM239,258$10.2M0.2%History
ADPTAdaptive Biotechnologies CorpCOM352,804$9.90M0.2%History
KYMRKymera Therapeutics, Inc.COM155,000$9.84M0.2%History
ONEM1Life Healthcare IncCOM532,350$9.35M0.1%History
CLDXCelldex Therapeutics, Inc.COM NEW229,807$8.88M0.1%History
EQRXEQRx, Inc.COM1,250,000$8.53M0.1%History
TBIOTelesis Bio Inc.COM425,000$4.59M0.1%History
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$3.78M0.1%–
AXSMAxsome Therapeutics, Inc.COM80,420$3.04M<0.1%History
PMVPPMV Pharmaceuticals, Inc.COM125,000$2.89M<0.1%History
YARWYarrow Bioscience, Inc.COM2,178,022$2.22M<0.1%History
ITOSiTeos Therapeutics, Inc.COM20,000$931.0K<0.1%History
EIGREiger BioPharmaceuticals, Inc.COM139,890$726.0K<0.1%History
PHVSPharvaris N.V.COM27,000$389.0K<0.1%History