Skip to main content
Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2022

Holdings as of Jun 30, 2022, filed Aug 15, 2022. Long positions only; changes compare share counts with Q1 2022.

Institution overview
Positions
109
−26 vs. Q1 2022
Portfolio value
$3.18B
−$1.63B (−33.9%) vs. Q1 2022
Filed
Aug 15, 2022
SEC
Holdings of Perceptive Advisors LLC in Q2 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$455.9M14.3%–––
FOLDAmicus Therapeutics, Inc.COM26,895,532$288.9M9.1%−660,313−2.4%ReducedHistory
MRTXMirati Therapeutics, Inc.COM2,866,863$192.5M6.0%+486,153+20.4%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM5,086,727$134.5M4.2%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM11,826,299$130.6M4.1%−374,962−3.1%ReducedHistory
LIANYLianBioSPONSORED ADS56,560,211$122.2M3.8%+240,251+0.4%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM5,321,032$99.2M3.1%+157,515+3.1%AddedHistory
GBTGlobal Blood Therapeutics, Inc.COM3,015,054$96.3M3.0%−877,439−22.5%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM3,867,446$95.2M3.0%−660,547−14.6%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM3,540,408$68.2M2.1%+2,066,301+140.2%AddedHistory
XENEXenon Pharmaceuticals Inc.COM2,122,535$64.6M2.0%−288,912−12.0%ReducedHistory
MGTXMeiraGTx Holdings plcCOM6,963,277$52.7M1.7%+15,000+0.2%AddedHistory
LYRALyra Therapeutics, Inc.COM9,146,730$51.7M1.6%+5,924,170+183.8%AddedHistory
Bellus Health Inc New07987C204COM NEW5,534,169$51.1M1.6%−2,602,461−32.0%Reduced–
RXDXPrometheus Biosciences, Inc.COM1,682,242$47.5M1.5%−758,340−31.1%ReducedHistory
ALBOAlbireo Pharma, Inc.COM2,360,139$46.9M1.5%00.0%UnchangedHistory
CINCCinCor Pharma, Inc.COM2,319,117$43.7M1.4%00.0%UnchangedHistory
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$42.3M1.3%00.0%UnchangedHistory
SGENSeagen Inc.COM224,000$39.6M1.2%+224,000NewHistory
VERUVeru Inc.COM3,500,000$39.5M1.2%−861,998−19.8%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM9,903,879$39.5M1.2%00.0%UnchangedHistory
NBIXNeurocrine Biosciences IncStock397,888$38.8M1.2%+2,249+0.6%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,913,791$34.9M1.1%−886,171−31.6%ReducedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$32.5M1.0%00.0%UnchangedHistory
LLYEli Lilly & CoStock100,000$32.4M1.0%+100,000NewHistory
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$29.5M0.9%–––
COGTCogent Biosciences, Inc.COM3,088,972$27.9M0.9%−99,778−3.1%ReducedHistory
CHRSCoherus Oncology, Inc.COM3,645,471$26.4M0.8%−1,050,377−22.4%ReducedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM367,501$26.3M0.8%+89,215+32.1%AddedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM172,991$25.2M0.8%−7,088−3.9%ReducedHistory
PRCTPROCEPT BioRobotics CorpCOM749,700$24.5M0.8%−738,584−49.6%ReducedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$24.5M0.8%00.0%UnchangedHistory
ADMAAdma Biologics, Inc.COM11,521,102$22.8M0.7%−412,285−3.5%ReducedHistory
NUVLNuvalent, Inc.COM1,655,007$22.4M0.7%−96,594−5.5%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM405,759$22.1M0.7%−44,615−9.9%ReducedHistory
ZYMEZymeworks Inc.COM4,132,534$21.9M0.7%−1,193,081−22.4%ReducedHistory
IMTXImmatics N.V.SHS2,500,000$21.8M0.7%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM1,914,592$21.7M0.7%+133,357+7.5%AddedHistory
ACLXArcellx, Inc.COMMON STOCK1,141,990$20.6M0.6%+1,141,990NewHistory
ISEEIVERIC bio, Inc.COM2,087,956$20.1M0.6%−3,137,459−60.0%ReducedHistory
HRMYHarmony Biosciences Holdings, Inc.COM411,804$20.1M0.6%+411,804NewHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$18.9M0.6%00.0%UnchangedHistory
AORTArtivion, Inc.COM929,705$17.6M0.6%+314,002+51.0%AddedHistory
DICEDICE Therapeutics, Inc.COM1,051,904$16.3M0.5%−463,457−30.6%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,166,883$16.1M0.5%−511,207−30.5%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,697,033$15.4M0.5%−2,142,347−55.8%ReducedHistory
BMRNBiomarin Pharmaceutical IncCOM180,000$14.9M0.5%+180,000NewHistory
OMOutset Medical, Inc.COM998,727$14.8M0.5%−884,672−47.0%ReducedHistory
LONALeonaBio, Inc.COM4,797,278$14.6M0.5%+1,371,362+40.0%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM321,300$14.5M0.5%−1,160,400−78.3%ReducedHistory
TVTXTravere Therapeutics, Inc.COM570,084$13.8M0.4%−1,275,471−69.1%ReducedHistory
Rain Oncology Inc.75082Q105COM2,483,619$13.8M0.4%00.0%Unchanged–
OMICSingular Genomics Systems, Inc.COM3,536,274$13.5M0.4%−118,933−3.3%ReducedHistory
TMCITreace Medical Concepts, Inc.COM941,192$13.5M0.4%−30,000−3.1%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS2,915,146$12.2M0.4%−129,157−4.2%ReducedHistory
VRDNViridian Therapeutics, Inc.COM971,832$11.2M0.4%−451,221−31.7%ReducedHistory
ChemoCentryx, Inc.16383L106COM441,680$10.9M0.3%−1,213,399−73.3%Reduced–
CMAXCareMax, Inc.COM CL A3,000,000$10.9M0.3%−186,663−5.9%ReducedHistory
LABPLandos Biopharma, Inc.COM14,869,915$10.8M0.3%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock556,047$9.95M0.3%00.0%UnchangedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$9.68M0.3%+1,428,571+39.6%AddedHistory
CYPHCypherpunk Technologies Inc.COM7,951,448$9.14M0.3%00.0%UnchangedHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$9.05M0.3%00.0%UnchangedHistory
ISOIsoPlexis CorpCOM4,095,498$8.85M0.3%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM2,421,142$8.81M0.3%00.0%UnchangedHistory
HLVXHilleVax, Inc.COM764,907$8.36M0.3%+764,907NewHistory
SLDBSolid Biosciences Inc.COM13,412,552$8.26M0.3%00.0%UnchangedHistory
PRVAPrivia Health Group, Inc.COM273,423$7.96M0.3%+60,000+28.1%AddedHistory
RVNCRevance Therapeutics, Inc.COM572,514$7.91M0.2%+435,000+316.3%AddedHistory
MORFMorphic Holding, Inc.COM363,197$7.88M0.2%−404,130−52.7%ReducedHistory
PNTPOINT Biopharma Global Inc.COM1,073,995$7.31M0.2%−120,000−10.1%ReducedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$6.78M0.2%00.0%UnchangedHistory
HCATHealth Catalyst, Inc.COM465,162$6.74M0.2%−28,500−5.8%ReducedHistory
WGSGeneDx Holdings Corp.COMMON STOCK5,000,000$6.30M0.2%+2,500,000+100.0%AddedHistory
ICVXIcosavax, Inc.COM1,042,850$5.98M0.2%−336,287−24.4%ReducedHistory
CCCCC4 Therapeutics, Inc.COM STK766,231$5.78M0.2%−1,316,492−63.2%ReducedHistory
NUVBNuvation Bio Inc.COM CL A1,769,701$5.73M0.2%00.0%UnchangedHistory
ATNXAthenex, Inc.COM13,532,467$5.54M0.2%00.0%UnchangedHistory
ACRSAclaris Therapeutics, Inc.COM341,239$4.76M0.1%−42,000−11.0%ReducedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$4.03M0.1%00.0%UnchangedHistory
QTNTQuotient LtdSHS16,200,818$3.89M0.1%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM1,281,197$3.84M0.1%00.0%UnchangedHistory
PYXSPyxis Oncology, Inc.COMMON STOCK1,528,812$3.64M0.1%00.0%UnchangedHistory
MGNXMacrogenics IncCOM1,227,202$3.62M0.1%−332,587−21.3%ReducedHistory
TYRATyra Biosciences, Inc.COM494,403$3.54M0.1%00.0%UnchangedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$3.21M0.1%00.0%UnchangedHistory
YMABY-mAbs Therapeutics, Inc.COM212,018$3.21M0.1%+212,018NewHistory
SNCEScience 37 Holdings, Inc.COM1,500,000$3.02M0.1%00.0%UnchangedHistory
ABSIAbsci CorpCOM894,346$2.97M0.1%−296,606−24.9%ReducedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$2.95M0.1%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM1,052,445$2.62M0.1%−174,572−14.2%ReducedHistory
HYPRHyperfine, Inc.COM CL A1,134,388$2.53M0.1%−365,612−24.4%ReducedHistory
ABOSAcumen Pharmaceuticals, Inc.COM508,532$2.39M0.1%−88,410−14.8%ReducedHistory
RLMDRelmada Therapeutics, Inc.COM121,350$2.30M0.1%−30,000−19.8%ReducedHistory
DRIODarioHealth Corp.COM NEW327,869$2.01M0.1%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$1.44M<0.1%00.0%UnchangedHistory
PEARPear Therapeutics, Inc.CLASS A COM900,548$1.39M<0.1%−25,684−2.8%ReducedHistory
RACEFerrari N.V.COM6,200$1.14M<0.1%00.0%UnchangedHistory
SONXSonendo, Inc.COM648,505$1.11M<0.1%−20,000−3.0%ReducedHistory
ZYZymergen Inc.COM883,332$1.09M<0.1%00.0%UnchangedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2022
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$7.43M–
FLNAFilana Therapeutics, Inc.COM$2.81M–

Sold out since Q1 2022 (33)

Positions held at the end of Q1 2022 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2022
SecurityClassShares in Q1 2022Value in Q1 2022% of portfolio in Q1 2022History
HZNPHorizon Therapeutics Public Ltd CoSHS1,357,903$142.9M3.0%History
Collegium Pharmaceutical, Inc19459JAA2NOTE 2.625% 2/1–$89.5M1.9%–
NVRONevro CorpCOM477,037$34.5M0.7%History
PENPenumbra IncCOM143,591$31.9M0.7%History
ZNTLZentalis Pharmaceuticals, Inc.COM501,509$23.1M0.5%History
LEGNLegend Biotech CorpSPONSORED ADS616,141$22.4M0.5%History
AXNXAxonics, Inc.COM341,211$21.4M0.4%History
LUNGPulmonx CorpCOM537,779$13.3M0.3%History
RCUSArcus Biosciences, Inc.COM405,000$12.8M0.3%History
Nanostring Technologies Inc63009RAD1NOTE 2.625% 5/0–$11.0M0.2%–
HLTHCue Health Inc.COM1,580,607$10.2M0.2%History
BCLS Acquisition CorpG0904B105COM CL A1,000,000$9.87M0.2%–
Summit Healthcre Acquistn CoG8566R128UNIT 06/03/20261,000,000$9.78M0.2%–
RACBResearch Alliance Corp. IICOM CL A1,000,000$9.76M0.2%History
EVHEvolent Health, Inc.CL A250,000$8.07M0.2%History
ACADAcadia Pharmaceuticals IncCOM284,853$6.90M0.1%History
ACCDAccolade, Inc.COM330,682$5.81M0.1%History
MRUSMerus N.V.COM209,046$5.53M0.1%History
DALSDA32 Life Science Tech Acquisition Corp.CLASS A COM500,000$4.86M0.1%History
SGHTSight Sciences, Inc.COM390,000$4.51M0.1%History
OBIOOrchestra BioMed Holdings, Inc.ORD SHS450,000$4.46M0.1%History
NVTAInvitae CorpCOM554,585$4.42M0.1%History
IMRXImmuneering CorpCLASS A COM681,051$4.41M0.1%History
NARIInari Medical, Inc.Stock30,000$2.72M0.1%History
PRTAProthena Corp Public Ltd CoSHS65,144$2.38M<0.1%History
LENZLENZ Therapeutics, Inc.COM325,854$1.66M<0.1%History
RETAReata Pharmaceuticals IncCL A44,475$1.46M<0.1%History
ONCROncorus, Inc.COM752,241$1.34M<0.1%History
RPIDRapid Micro Biosystems, Inc.CLASS A COM190,745$1.29M<0.1%History
Rockley Photonics Holdings LG7614L117*W EXP 08/11/202500,000$425.0K<0.1%–
Butterfly Network, Inc.124155110*W EXP 05/27/202233,333$238.0K<0.1%–
SLGCWSomaLogic, Inc.*W EXP 03/01/202110,000$235.0K<0.1%History
UTRSMinerva Surgical IncCOM50,268$226.0K<0.1%History