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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2022

Holdings as of Sep 30, 2022, filed Nov 14, 2022. Long positions only; changes compare share counts with Q2 2022.

Institution overview
Positions
115
+6 vs. Q2 2022
Portfolio value
$3.44B
+$257.8M (+8.1%) vs. Q2 2022
Filed
Nov 14, 2022
SEC
Holdings of Perceptive Advisors LLC in Q3 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
FOLDAmicus Therapeutics, Inc.COM27,372,917$285.8M8.3%+477,385+1.8%AddedHistory
MRTXMirati Therapeutics, Inc.COM2,784,796$194.5M5.7%−82,067−2.9%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM6,511,727$184.0M5.3%+1,425,000+28.0%AddedHistory
GBTGlobal Blood Therapeutics, Inc.COM2,322,247$158.1M4.6%−692,807−23.0%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM5,472,033$154.0M4.5%+1,931,625+54.6%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$115.1M3.3%+998,240+1.8%AddedHistory
CINCCinCor Pharma, Inc.COM3,306,649$108.5M3.2%+987,532+42.6%AddedHistory
Bellus Health Inc New07987C204COM NEW10,247,073$108.2M3.1%+4,712,904+85.2%Added–
CRNXCrinetics Pharmaceuticals, Inc.COM5,321,032$104.5M3.0%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM3,470,563$99.0M2.9%−396,883−10.3%ReducedHistory
IOVAIovance Biotherapeutics, Inc.COM10,248,624$98.2M2.9%−1,577,675−13.3%ReducedHistory
RLMDRelmada Therapeutics, Inc.COM2,383,478$88.2M2.6%+2,262,128+1,864.1%AddedHistory
RXDXPrometheus Biosciences, Inc.COM1,468,512$86.7M2.5%−213,730−12.7%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM2,122,535$76.6M2.2%00.0%UnchangedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$60.6M1.8%+1,446,206+14.6%AddedHistory
MGTXMeiraGTx Holdings plcCOM6,963,277$58.6M1.7%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM2,887,860$51.8M1.5%+973,268+50.8%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS5,047,264$51.6M1.5%+2,132,118+73.1%AddedHistory
COGTCogent Biosciences, Inc.COM3,207,441$47.9M1.4%+118,469+3.8%AddedHistory
ACLXArcellx, Inc.COMMON STOCK2,465,405$46.3M1.3%+1,323,415+115.9%AddedHistory
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$46.0M1.3%–––
LYRALyra Therapeutics, Inc.COM9,146,730$45.8M1.3%00.0%UnchangedHistory
ALBOAlbireo Pharma, Inc.COM2,360,139$45.7M1.3%00.0%UnchangedHistory
VERUVeru Inc.COM3,893,000$44.8M1.3%+393,000+11.2%AddedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$43.5M1.3%00.0%UnchangedHistory
SGENSeagen Inc.COM316,544$43.3M1.3%+92,544+41.3%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,713,134$41.2M1.2%−200,657−10.5%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$37.2M1.1%00.0%UnchangedHistory
TMCITreace Medical Concepts, Inc.COM1,601,979$35.4M1.0%+660,787+70.2%AddedHistory
NUVLNuvalent, Inc.COM1,655,007$32.2M0.9%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM578,253$31.6M0.9%+172,494+42.5%AddedHistory
BMRNBiomarin Pharmaceutical IncCOM336,481$28.5M0.8%+156,481+86.9%AddedHistory
SRPTSarepta Therapeutics, Inc.COM253,000$28.0M0.8%+253,000NewHistory
EWEdwards Lifesciences CorpStock330,000$27.3M0.8%+330,000NewHistory
ZYMEZymeworks Inc.COM4,400,099$27.1M0.8%+267,565+6.5%AddedHistory
ADMAAdma Biologics, Inc.COM10,933,387$26.6M0.8%−587,715−5.1%ReducedHistory
VRDNViridian Therapeutics, Inc.COM1,220,575$25.0M0.7%+248,743+25.6%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM366,400$25.0M0.7%+45,100+14.0%AddedHistory
IMTXImmatics N.V.SHS2,500,000$25.0M0.7%00.0%UnchangedHistory
CMAXCareMax, Inc.COM CL A3,394,939$24.1M0.7%+394,939+13.2%AddedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$22.2M0.6%00.0%UnchangedHistory
RVNCRevance Therapeutics, Inc.COM808,671$21.8M0.6%+236,157+41.2%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM331,023$21.5M0.6%−36,478−9.9%ReducedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$19.3M0.6%00.0%UnchangedHistory
CTKBCytek Biosciences, Inc.COM1,289,534$19.0M0.6%+1,289,534NewHistory
OMOutset Medical, Inc.COM1,168,630$18.6M0.5%+169,903+17.0%AddedHistory
ISEEIVERIC bio, Inc.COM1,034,169$18.6M0.5%−1,053,787−50.5%ReducedHistory
HRMYHarmony Biosciences Holdings, Inc.COM411,804$18.2M0.5%00.0%UnchangedHistory
RCUSArcus Biosciences, Inc.COM666,477$17.4M0.5%+666,477NewHistory
BBIOBridgeBio Pharma, Inc.COM1,697,033$16.9M0.5%00.0%UnchangedHistory
AORTArtivion, Inc.COM1,204,229$16.7M0.5%+274,524+29.5%AddedHistory
CHRSCoherus Oncology, Inc.COM1,667,123$16.0M0.5%−1,978,348−54.3%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$14.7M0.4%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM430,000$14.6M0.4%+430,000NewHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$14.4M0.4%00.0%UnchangedHistory
LONALeonaBio, Inc.COM4,797,278$14.2M0.4%00.0%UnchangedHistory
PRTAProthena Corp Public Ltd CoSHS230,000$13.9M0.4%+230,000NewHistory
DICEDICE Therapeutics, Inc.COM687,424$13.9M0.4%−364,480−34.6%ReducedHistory
HLVXHilleVax, Inc.COM764,907$13.1M0.4%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM2,483,619$12.1M0.4%00.0%Unchanged–
ATXSAstria Therapeutics, Inc.COM1,281,197$11.6M0.3%00.0%UnchangedHistory
AXGNAxogen, Inc.COM949,626$11.3M0.3%+949,626NewHistory
PRCTPROCEPT BioRobotics CorpCOM263,720$10.9M0.3%−485,980−64.8%ReducedHistory
NBIXNeurocrine Biosciences IncStock100,050$10.6M0.3%−297,838−74.9%ReducedHistory
MORFMorphic Holding, Inc.COM363,197$10.3M0.3%00.0%UnchangedHistory
ChemoCentryx, Inc.16383L106COM192,680$9.95M0.3%−249,000−56.4%Reduced–
LABPLandos Biopharma, Inc.COM14,869,915$9.66M0.3%00.0%UnchangedHistory
LRMRLarimar Therapeutics, Inc.COM2,860,000$9.15M0.3%+2,860,000NewHistory
OMICSingular Genomics Systems, Inc.COM3,536,274$8.84M0.3%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM500,000$7.98M0.2%−666,883−57.2%ReducedHistory
KRONKronos Bio, Inc.COM2,156,151$7.22M0.2%−264,991−10.9%ReducedHistory
ISOIsoPlexis CorpCOM4,095,498$7.04M0.2%00.0%UnchangedHistory
NVRONevro CorpCOM150,000$6.99M0.2%+150,000NewHistory
CCCCC4 Therapeutics, Inc.COM STK766,231$6.72M0.2%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM7,472,148$6.58M0.2%−479,300−6.0%ReducedHistory
SLDBSolid Biosciences Inc.COM13,412,552$6.26M0.2%00.0%UnchangedHistory
RVMDRevolution Medicines, Inc.COM310,500$6.12M0.2%+310,500NewHistory
ACRSAclaris Therapeutics, Inc.COM341,239$5.37M0.2%00.0%UnchangedHistory
NTRANatera, Inc.COM120,000$5.26M0.2%+120,000NewHistory
NARIInari Medical, Inc.Stock70,000$5.08M0.1%+70,000NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$4.91M0.1%00.0%UnchangedHistory
WGSGeneDx Holdings Corp.COMMON STOCK5,000,000$4.39M0.1%00.0%UnchangedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$4.35M0.1%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM494,403$4.35M0.1%00.0%UnchangedHistory
CTICCti Biopharma CorpCOM735,165$4.28M0.1%+735,165NewHistory
ATNXAthenex, Inc.COM15,532,467$4.18M0.1%+2,000,000+14.8%AddedHistory
ABOSAcumen Pharmaceuticals, Inc.COM400,000$4.01M0.1%−108,532−21.3%ReducedHistory
PNTPOINT Biopharma Global Inc.COM500,000$3.87M0.1%−573,995−53.4%ReducedHistory
HCATHealth Catalyst, Inc.COM389,962$3.78M0.1%−75,200−16.2%ReducedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$3.75M0.1%00.0%UnchangedHistory
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$3.59M0.1%–––
YMABY-mAbs Therapeutics, Inc.COM212,018$3.06M0.1%00.0%UnchangedHistory
PYXSPyxis Oncology, Inc.COMMON STOCK1,528,812$3.01M0.1%00.0%UnchangedHistory
ABSIAbsci CorpCOM894,346$2.80M0.1%00.0%UnchangedHistory
PSTXPoseida Therapeutics, Inc.COM750,000$2.65M0.1%+750,000NewHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$2.55M0.1%00.0%UnchangedHistory
RETAReata Pharmaceuticals IncCL A100,000$2.51M0.1%+100,000NewHistory
QTNTQuotient LtdSHS16,200,818$2.43M0.1%00.0%UnchangedHistory
SNCEScience 37 Holdings, Inc.COM1,500,000$2.42M0.1%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$2.38M0.1%00.0%UnchangedHistory

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2022
SecurityClassPutsCalls
TCDATricida, Inc.COM$5.24M–

Sold out since Q2 2022 (9)

Positions held at the end of Q2 2022 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2022
SecurityClassShares in Q2 2022Value in Q2 2022% of portfolio in Q2 2022History
LLYEli Lilly & CoStock100,000$32.4M1.0%History
ALNYAlnylam Pharmaceuticals, Inc.COM172,991$25.2M0.8%History
DAWNDay One Biopharmaceuticals, Inc.Stock556,047$9.95M0.3%History
PRVAPrivia Health Group, Inc.COM273,423$7.96M0.3%History
NUVBNuvation Bio Inc.COM CL A1,769,701$5.73M0.2%History
MGNXMacrogenics IncCOM1,227,202$3.62M0.1%History
FUSNFusion Pharmaceuticals Inc.COM1,052,445$2.62M0.1%History
RACEFerrari N.V.COM6,200$1.14M<0.1%History
ZYZymergen Inc.COM883,332$1.09M<0.1%History