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Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2021

Holdings as of Sep 30, 2021, filed Dec 3, 2021. Long positions only; changes compare share counts with Q2 2021.

Institution overview
Positions
138
−10 vs. Q2 2021
Portfolio value
$6.86B
−$827.2M (−10.8%) vs. Q2 2021
Filed
Dec 3, 2021
AmendedSEC
Holdings of Perceptive Advisors LLC in Q3 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
BCLS Acquisition CorpG0904B105COM CL A1,000,000$9.96M0.1%00.0%Unchanged–
FUSNFusion Pharmaceuticals Inc.COM1,254,607$9.94M0.1%−520,560−29.3%ReducedHistory
RACBResearch Alliance Corp. IICOM CL A1,000,000$9.85M0.1%00.0%UnchangedHistory
PNTPOINT Biopharma Global Inc.COM1,242,879$9.56M0.1%+1,242,879NewHistory
ChemoCentryx, Inc.16383L106COM550,000$9.40M0.1%+550,000New–
PMVPPMV Pharmaceuticals, Inc.COM301,714$8.99M0.1%−444,843−59.6%ReducedHistory
SGHTSight Sciences, Inc.COM390,000$8.85M0.1%+390,000NewHistory
FULCFulcrum Therapeutics, Inc.COM294,118$8.30M0.1%00.0%UnchangedHistory
PRTAProthena Corp Public Ltd CoSHS100,000$7.12M0.1%00.0%UnchangedHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$7.03M0.1%00.0%UnchangedHistory
RPIDRapid Micro Biosystems, Inc.CLASS A COM350,000$6.46M0.1%+350,000NewHistory
NEPTFNeptune Wellness Solutions Inc.COM10,055,521$6.08M0.1%−2,794,185−21.7%ReducedHistory
PRVBProvention Bio, Inc.COM948,481$6.07M0.1%00.0%UnchangedHistory
TSHATaysha Gene Therapies, Inc.COM SHS320,440$5.97M0.1%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$5.88M0.1%00.0%Unchanged–
PSTXPoseida Therapeutics, Inc.COM787,745$5.74M0.1%00.0%UnchangedHistory
ATECAlphatec Holdings, Inc.COM NEW430,900$5.25M0.1%−1,369,280−76.1%ReducedHistory
DALSDA32 Life Science Tech Acquisition Corp.CLASS A COM500,000$4.92M0.1%+500,000NewHistory
TBIOTelesis Bio Inc.COM425,000$4.73M0.1%00.0%UnchangedHistory
DRIODarioHealth Corp.COM NEW327,869$4.47M0.1%00.0%UnchangedHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS450,000$4.45M0.1%00.0%UnchangedHistory
RGNXREGENXBIO Inc.COM89,283$3.74M0.1%00.0%UnchangedHistory
SRZNSurrozen, Inc.COM500,000$3.54M0.1%+500,000NewHistory
YARWYarrow Bioscience, Inc.COM2,330,471$3.24M<0.1%−3,443,483−59.6%ReducedHistory
SNCEScience 37 Holdings, Inc.COM300,000$2.94M<0.1%00.0%UnchangedHistory
TARAProtara Therapeutics, Inc.COM STK421,641$2.92M<0.1%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM80,420$2.65M<0.1%−473,488−85.5%ReducedHistory
IMGOImago BioSciences, Inc.COM125,000$2.50M<0.1%+125,000NewHistory
KRROKorro Bio, Inc.COM222,222$1.57M<0.1%00.0%UnchangedHistory
RACEFerrari N.V.COM6,200$1.30M<0.1%00.0%UnchangedHistory
MOTSMotus GI Holdings, Inc.COM1,800,542$1.24M<0.1%00.0%UnchangedHistory
Rockley Photonics Holdings LG7614L117*W EXP 08/11/202500,000$1.20M<0.1%+500,000New–
EIGREiger BioPharmaceuticals, Inc.COM139,890$934.0K<0.1%00.0%UnchangedHistory
Butterfly Network, Inc.124155110*W EXP 05/27/202233,333$642.0K<0.1%00.0%Unchanged–
PHVSPharvaris N.V.COM27,000$479.0K<0.1%00.0%UnchangedHistory
SLGCWSomaLogic, Inc.*W EXP 03/01/202110,000$380.0K<0.1%+110,000NewHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$190.0K<0.1%+166,666New–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$170.0K<0.1%00.0%Unchanged–

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2021
SecurityClassPutsCalls
ChemoCentryx, Inc.16383L106COM–$15.8M
FLNAFilana Therapeutics, Inc.COM$6.21M–

Sold out since Q2 2021 (34)

Positions held at the end of Q2 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2021
SecurityClassShares in Q2 2021Value in Q2 2021% of portfolio in Q2 2021History
KDMNKadmon Holdings, Inc.COM15,711,334$60.8M0.8%History
MDTMedtronic plcStock450,000$55.9M0.7%History
DRNADicerna Pharmaceuticals IncCOM800,000$29.9M0.4%History
EXASExact Sciences CorpCOM233,523$29.0M0.4%History
NARIInari Medical, Inc.Stock310,437$29.0M0.4%History
XLRNAcceleron Pharma IncCOM226,760$28.5M0.4%History
RGENRepligen CorpCOM132,500$26.4M0.3%History
ARWRArrowhead Pharmaceuticals, Inc.COM315,141$26.1M0.3%History
COLLCollegium Pharmaceutical, IncCOM978,277$23.1M0.3%History
FBRXForte Biosciences, Inc.COM685,000$23.0M0.3%History
STOKStoke Therapeutics, Inc.COM671,978$22.6M0.3%History
CM Life Sciences II Inc125842203UNIT 02/25/20281,250,000$16.8M0.2%–
Catabasis Pharmaceuticals IN14875P206COM NEW7,687,185$16.2M0.2%–
Therapeutics Acquisition Cor88339T103COM CL A1,500,000$15.4M0.2%–
CVRXCVRx, Inc.COM440,000$12.3M0.2%History
CTMXCytomX Therapeutics, Inc.COM1,640,957$10.4M0.1%History
SILKSilk Road Medical IncCOM147,133$7.04M0.1%History
PRVAPrivia Health Group, Inc.COM135,000$5.99M0.1%History
AKYAAkoya Biosciences, Inc.COM300,000$5.80M0.1%History
BCTG Acquisition Corp05492W103COM500,000$5.69M0.1%–
MREOMereo BioPharma Group plcSPON ADS1,696,068$5.38M0.1%History
Consonance HFW Acquisition CG2445M129UNIT 99/99/9999500,000$5.20M0.1%–
Longview Acquisition Corp. II54319Q204UNIT 99/99/9999500,000$5.04M0.1%–
MRUSMerus N.V.COM175,000$3.69M<0.1%History
AMWLAmerican Well CorpCL A290,000$3.65M<0.1%History
CM Life Sciences Inc18978W109COM CL A227,000$3.18M<0.1%–
GRTXGalera Therapeutics, Inc.COM254,664$2.50M<0.1%History
Cerevel Therapeutics HLDNG I15678U102*W EXP 06/09/202133,066$1.91M<0.1%–
SGTXSigilon Therapeutics, Inc.COM125,000$1.34M<0.1%History
SRRASierra Oncology, Inc.COM NEW66,655$1.30M<0.1%History
SC Health CorpG78516401*W EXP 99/99/999500,000$1.05M<0.1%–
PLXPPLx Pharma Winddown Corp.COM57,459$793.0K<0.1%History
TKNOAlpha Teknova, Inc.COM30,000$712.0K<0.1%History
TCRRTCR2 Therapeutics Inc.COM30,753$505.0K<0.1%History