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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2021

Holdings as of Sep 30, 2021, filed Dec 3, 2021. Long positions only; changes compare share counts with Q2 2021.

Institution overview
Positions
138
−10 vs. Q2 2021
Portfolio value
$6.86B
−$827.2M (−10.8%) vs. Q2 2021
Filed
Dec 3, 2021
AmendedSEC
Holdings of Perceptive Advisors LLC in Q3 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$170.0K<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$190.0K<0.1%+166,666New–
SLGCWSomaLogic, Inc.*W EXP 03/01/202110,000$380.0K<0.1%+110,000NewHistory
PHVSPharvaris N.V.COM27,000$479.0K<0.1%00.0%UnchangedHistory
Butterfly Network, Inc.124155110*W EXP 05/27/202233,333$642.0K<0.1%00.0%Unchanged–
EIGREiger BioPharmaceuticals, Inc.COM139,890$934.0K<0.1%00.0%UnchangedHistory
Rockley Photonics Holdings LG7614L117*W EXP 08/11/202500,000$1.20M<0.1%+500,000New–
MOTSMotus GI Holdings, Inc.COM1,800,542$1.24M<0.1%00.0%UnchangedHistory
RACEFerrari N.V.COM6,200$1.30M<0.1%00.0%UnchangedHistory
KRROKorro Bio, Inc.COM222,222$1.57M<0.1%00.0%UnchangedHistory
IMGOImago BioSciences, Inc.COM125,000$2.50M<0.1%+125,000NewHistory
AXSMAxsome Therapeutics, Inc.COM80,420$2.65M<0.1%−473,488−85.5%ReducedHistory
TARAProtara Therapeutics, Inc.COM STK421,641$2.92M<0.1%00.0%UnchangedHistory
SNCEScience 37 Holdings, Inc.COM300,000$2.94M<0.1%00.0%UnchangedHistory
YARWYarrow Bioscience, Inc.COM2,330,471$3.24M<0.1%−3,443,483−59.6%ReducedHistory
SRZNSurrozen, Inc.COM500,000$3.54M0.1%+500,000NewHistory
RGNXREGENXBIO Inc.COM89,283$3.74M0.1%00.0%UnchangedHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS450,000$4.45M0.1%00.0%UnchangedHistory
DRIODarioHealth Corp.COM NEW327,869$4.47M0.1%00.0%UnchangedHistory
TBIOTelesis Bio Inc.COM425,000$4.73M0.1%00.0%UnchangedHistory
DALSDA32 Life Science Tech Acquisition Corp.CLASS A COM500,000$4.92M0.1%+500,000NewHistory
ATECAlphatec Holdings, Inc.COM NEW430,900$5.25M0.1%−1,369,280−76.1%ReducedHistory
PSTXPoseida Therapeutics, Inc.COM787,745$5.74M0.1%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$5.88M0.1%00.0%Unchanged–
TSHATaysha Gene Therapies, Inc.COM SHS320,440$5.97M0.1%00.0%UnchangedHistory
PRVBProvention Bio, Inc.COM948,481$6.07M0.1%00.0%UnchangedHistory
NEPTFNeptune Wellness Solutions Inc.COM10,055,521$6.08M0.1%−2,794,185−21.7%ReducedHistory
RPIDRapid Micro Biosystems, Inc.CLASS A COM350,000$6.46M0.1%+350,000NewHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$7.03M0.1%00.0%UnchangedHistory
PRTAProthena Corp Public Ltd CoSHS100,000$7.12M0.1%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$8.30M0.1%00.0%UnchangedHistory
SGHTSight Sciences, Inc.COM390,000$8.85M0.1%+390,000NewHistory
PMVPPMV Pharmaceuticals, Inc.COM301,714$8.99M0.1%−444,843−59.6%ReducedHistory
ChemoCentryx, Inc.16383L106COM550,000$9.40M0.1%+550,000New–
PNTPOINT Biopharma Global Inc.COM1,242,879$9.56M0.1%+1,242,879NewHistory
RACBResearch Alliance Corp. IICOM CL A1,000,000$9.85M0.1%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM1,254,607$9.94M0.1%−520,560−29.3%ReducedHistory
BCLS Acquisition CorpG0904B105COM CL A1,000,000$9.96M0.1%00.0%Unchanged–
Summit Healthcre Acquistn CoG8566R128UNIT 06/03/20261,000,000$10.1M0.1%00.0%Unchanged–
FDMT4D Molecular Therapeutics, Inc.COM375,256$10.1M0.1%00.0%UnchangedHistory
ONCROncorus, Inc.COM1,099,810$10.3M0.1%−363,789−24.9%ReducedHistory
KYMRKymera Therapeutics, Inc.COM180,000$10.6M0.2%+180,000NewHistory
ONEM1Life Healthcare IncCOM532,350$10.8M0.2%+16,306+3.2%AddedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$11.1M0.2%00.0%UnchangedHistory
ZYZymergen Inc.COM883,332$11.6M0.2%−750,000−45.9%ReducedHistory
ACCDAccolade, Inc.COM279,774$11.8M0.2%+34,033+13.8%AddedHistory
ADPTAdaptive Biotechnologies CorpCOM352,804$12.0M0.2%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$12.0M0.2%00.0%UnchangedHistory
PODDInsulet CorpStock44,522$12.7M0.2%+44,522NewHistory
Nanostring Technologies Inc63009RAD1NOTE 2.625% 5/0–$12.8M0.2%–––
CM Life Sciences III Inc125841205UNIT 04/30/20281,250,000$12.8M0.2%00.0%Unchanged–
DAWNDay One Biopharmaceuticals, Inc.Stock556,047$13.2M0.2%−200,000−26.5%ReducedHistory
VTRSViatris IncStock1,004,419$13.6M0.2%00.0%UnchangedHistory
BIIBBiogen Inc.COM48,600$13.8M0.2%+48,600NewHistory
ACRSAclaris Therapeutics, Inc.COM781,236$14.1M0.2%−68,764−8.1%ReducedHistory
LENZLENZ Therapeutics, Inc.COM875,093$14.3M0.2%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS400,000$14.8M0.2%00.0%UnchangedHistory
HYPRHyperfine, Inc.CL A SHS1,500,000$14.8M0.2%00.0%UnchangedHistory
ADMAAdma Biologics, Inc.COM13,262,375$15.0M0.2%−3,322,427−20.0%ReducedHistory
AGRXAgile Therapeutics IncCOM15,919,925$15.3M0.2%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS2,888,889$15.8M0.2%00.0%UnchangedHistory
NUVLNuvalent, Inc.COM750,000$16.9M0.2%+750,000NewHistory
ABSIAbsci CorpCOM1,476,776$17.2M0.3%+1,476,776NewHistory
ATXSAstria Therapeutics, Inc.COM1,959,652$17.3M0.3%+1,959,652NewHistory
TYRATyra Biosciences, Inc.COM987,500$17.4M0.3%+987,500NewHistory
NTRANatera, Inc.COM160,000$17.8M0.3%+160,000NewHistory
IMRXImmuneering CorpCLASS A COM681,051$18.1M0.3%+681,051NewHistory
HLTHCue Health Inc.COM1,580,607$18.7M0.3%+1,580,607NewHistory
HRMYHarmony Biosciences Holdings, Inc.COM491,332$18.8M0.3%00.0%UnchangedHistory
WGSGeneDx Holdings Corp.COMMON STOCK2,500,000$19.0M0.3%+2,500,000NewHistory
APLSApellis Pharmaceuticals, Inc.COM615,000$20.3M0.3%−46,162−7.0%ReducedHistory
CLDXCelldex Therapeutics, Inc.COM NEW393,613$21.3M0.3%−349,086−47.0%ReducedHistory
Avidity Biosciences, Inc.05370A108COM885,818$21.8M0.3%−193,210−17.9%Reduced–
VRDNViridian Therapeutics, Inc.COM1,423,000$23.4M0.3%+628,494+79.1%AddedHistory
BCABBioAtla, Inc.COM850,026$25.0M0.4%+164,507+24.0%AddedHistory
SLGCSomaLogic, Inc.CLASS A COM2,050,000$25.4M0.4%+2,050,000NewHistory
UTHRUnited Therapeutics CorpCOM141,700$26.2M0.4%−475,102−77.0%ReducedHistory
COGTCogent Biosciences, Inc.COM3,188,750$26.8M0.4%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$27.9M0.4%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM3,222,560$29.4M0.4%00.0%UnchangedHistory
HCATHealth Catalyst, Inc.COM589,004$29.5M0.4%+22,920+4.0%AddedHistory
NUVBNuvation Bio Inc.COM CL A3,041,004$30.2M0.4%00.0%UnchangedHistory
NVRONevro CorpCOM259,972$30.3M0.4%−558,788−68.2%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM2,022,051$30.9M0.5%+343,078+20.4%AddedHistory
SLDBSolid Biosciences Inc.COM13,412,552$32.1M0.5%00.0%UnchangedHistory
LONALeonaBio, Inc.COM3,425,916$32.1M0.5%00.0%UnchangedHistory
IMTXImmatics N.V.SHS2,500,000$32.5M0.5%00.0%UnchangedHistory
CMAXCareMax, Inc.COM CL A3,385,000$32.7M0.5%+65,000+2.0%AddedHistory
TMCITreace Medical Concepts, Inc.COM1,235,886$33.2M0.5%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM8,476,496$34.0M0.5%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM3,073,824$34.4M0.5%−9,046−0.3%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM505,541$36.2M0.5%−194,867−27.8%ReducedHistory
INBXInhibrx Biosciences, Inc.COM1,121,490$37.4M0.5%+214,400+23.6%AddedHistory
DBVTDBV Technologies S.A.SPONSORED ADR7,695,505$37.7M0.5%00.0%UnchangedHistory
QTNTQuotient LtdSHS16,200,818$37.9M0.6%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM2,537,019$38.0M0.6%00.0%Unchanged–
VERUVeru Inc.COM4,451,342$38.0M0.6%00.0%UnchangedHistory
ATNXAthenex, Inc.COM13,532,467$40.7M0.6%00.0%UnchangedHistory
KODKodiak Sciences Inc.COM461,248$44.3M0.6%+175,207+61.3%AddedHistory
MGNXMacrogenics IncCOM2,148,060$45.0M0.7%00.0%UnchangedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2021
SecurityClassPutsCalls
ChemoCentryx, Inc.16383L106COM–$15.8M
FLNAFilana Therapeutics, Inc.COM$6.21M–

Sold out since Q2 2021 (34)

Positions held at the end of Q2 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2021
SecurityClassShares in Q2 2021Value in Q2 2021% of portfolio in Q2 2021History
KDMNKadmon Holdings, Inc.COM15,711,334$60.8M0.8%History
MDTMedtronic plcStock450,000$55.9M0.7%History
DRNADicerna Pharmaceuticals IncCOM800,000$29.9M0.4%History
EXASExact Sciences CorpCOM233,523$29.0M0.4%History
NARIInari Medical, Inc.Stock310,437$29.0M0.4%History
XLRNAcceleron Pharma IncCOM226,760$28.5M0.4%History
RGENRepligen CorpCOM132,500$26.4M0.3%History
ARWRArrowhead Pharmaceuticals, Inc.COM315,141$26.1M0.3%History
COLLCollegium Pharmaceutical, IncCOM978,277$23.1M0.3%History
FBRXForte Biosciences, Inc.COM685,000$23.0M0.3%History
STOKStoke Therapeutics, Inc.COM671,978$22.6M0.3%History
CM Life Sciences II Inc125842203UNIT 02/25/20281,250,000$16.8M0.2%–
Catabasis Pharmaceuticals IN14875P206COM NEW7,687,185$16.2M0.2%–
Therapeutics Acquisition Cor88339T103COM CL A1,500,000$15.4M0.2%–
CVRXCVRx, Inc.COM440,000$12.3M0.2%History
CTMXCytomX Therapeutics, Inc.COM1,640,957$10.4M0.1%History
SILKSilk Road Medical IncCOM147,133$7.04M0.1%History
PRVAPrivia Health Group, Inc.COM135,000$5.99M0.1%History
AKYAAkoya Biosciences, Inc.COM300,000$5.80M0.1%History
BCTG Acquisition Corp05492W103COM500,000$5.69M0.1%–
MREOMereo BioPharma Group plcSPON ADS1,696,068$5.38M0.1%History
Consonance HFW Acquisition CG2445M129UNIT 99/99/9999500,000$5.20M0.1%–
Longview Acquisition Corp. II54319Q204UNIT 99/99/9999500,000$5.04M0.1%–
MRUSMerus N.V.COM175,000$3.69M<0.1%History
AMWLAmerican Well CorpCL A290,000$3.65M<0.1%History
CM Life Sciences Inc18978W109COM CL A227,000$3.18M<0.1%–
GRTXGalera Therapeutics, Inc.COM254,664$2.50M<0.1%History
Cerevel Therapeutics HLDNG I15678U102*W EXP 06/09/202133,066$1.91M<0.1%–
SGTXSigilon Therapeutics, Inc.COM125,000$1.34M<0.1%History
SRRASierra Oncology, Inc.COM NEW66,655$1.30M<0.1%History
SC Health CorpG78516401*W EXP 99/99/999500,000$1.05M<0.1%–
PLXPPLx Pharma Winddown Corp.COM57,459$793.0K<0.1%History
TKNOAlpha Teknova, Inc.COM30,000$712.0K<0.1%History
TCRRTCR2 Therapeutics Inc.COM30,753$505.0K<0.1%History