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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2021

Holdings as of Jun 30, 2021, filed Aug 17, 2021. Long positions only; changes compare share counts with Q1 2021.

Institution overview
Positions
148
+12 vs. Q1 2021
Portfolio value
$7.69B
+$165.9M (+2.2%) vs. Q1 2021
Filed
Aug 17, 2021
AmendedSEC
Holdings of Perceptive Advisors LLC in Q2 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
MRTXMirati Therapeutics, Inc.COM3,185,898$514.6M6.7%−288,607−8.3%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM7,756,928$472.9M6.1%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM4,849,912$399.7M5.2%00.0%UnchangedHistory
Retrophin Inc761299AB2NOTE 2.500% 9/1–$384.4M5.0%–––
IOVAIovance Biotherapeutics, Inc.COM10,959,772$285.2M3.7%+2,307,987+26.7%AddedHistory
FOLDAmicus Therapeutics, Inc.COM23,121,329$222.9M2.9%+260,000+1.1%AddedHistory
Collegium Pharmaceutical, Inc19459JAA2NOTE 2.625% 2/1–$189.7M2.5%–––
HZNPHorizon Therapeutics Public Ltd CoSHS1,985,002$185.9M2.4%−65,000−3.2%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM NEW55,042,465$184.4M2.4%00.0%UnchangedHistory
LABPLandos Biopharma, Inc.COM14,869,915$171.7M2.2%00.0%UnchangedHistory
NVTAInvitae CorpCOM4,818,801$162.5M2.1%−541,872−10.1%ReducedHistory
Nevro Corp64157FAC7NOTE 2.750% 4/0–$156.3M2.0%–––
ZYMEZymeworks Inc.COM4,305,600$149.4M1.9%−25,268−0.6%ReducedHistory
GBTGlobal Blood Therapeutics, Inc.COM4,152,689$145.4M1.9%−905,953−17.9%ReducedHistory
NVRONevro CorpCOM818,760$135.7M1.8%+6,606+0.8%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM2,751,603$121.9M1.6%−116,168−4.1%ReducedHistory
OMOutset Medical, Inc.COM2,387,535$119.3M1.6%00.0%UnchangedHistory
CERECerevel Therapeutics Holdings, Inc.COM4,643,095$119.0M1.5%00.0%UnchangedHistory
ALDXAldeyra Therapeutics, Inc.COM9,903,879$112.2M1.5%+1,200,000+13.8%AddedHistory
UTHRUnited Therapeutics CorpCOM616,802$110.7M1.4%+441,802+252.5%AddedHistory
MGTXMeiraGTx Holdings plcCOM6,948,277$107.7M1.4%+15,000+0.2%AddedHistory
NAUTNautilus Biotechnology, Inc.COM8,911,151$90.0M1.2%+8,911,151NewHistory
CCCCC4 Therapeutics, Inc.COM STK2,258,566$85.5M1.1%−900,000−28.5%ReducedHistory
OMICSingular Genomics Systems, Inc.COM3,082,870$84.7M1.1%+3,082,870NewHistory
ALBOAlbireo Pharma, Inc.COM2,360,139$83.0M1.1%00.0%UnchangedHistory
RXDXPrometheus Biosciences, Inc.COM3,314,032$81.4M1.1%00.0%UnchangedHistory
NBIXNeurocrine Biosciences IncStock811,832$79.0M1.0%−130,000−13.8%ReducedHistory
RAPTRAPT Therapeutics, Inc.COM2,475,660$78.7M1.0%−1,821−0.1%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM3,963,517$74.7M1.0%+304,136+8.3%AddedHistory
RLAYRelay Therapeutics, Inc.COM2,018,097$73.8M1.0%00.0%UnchangedHistory
BEAMBeam Therapeutics Inc.COM537,635$69.2M0.9%00.0%UnchangedHistory
ZYZymergen Inc.COM1,633,332$65.3M0.8%+1,633,332NewHistory
CHRSCoherus Oncology, Inc.COM4,697,612$65.0M0.8%00.0%UnchangedHistory
ATNXAthenex, Inc.COM13,532,467$62.5M0.8%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM700,408$61.2M0.8%−286,879−29.1%ReducedHistory
KDMNKadmon Holdings, Inc.COM15,711,334$60.8M0.8%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM2,528,052$60.5M0.8%−252,045−9.1%ReducedHistory
QTNTQuotient LtdSHS16,200,818$59.0M0.8%00.0%UnchangedHistory
MGNXMacrogenics IncCOM2,148,060$57.7M0.8%00.0%UnchangedHistory
MDTMedtronic plcStock450,000$55.9M0.7%+450,000NewHistory
MORFMorphic Holding, Inc.COM938,140$53.8M0.7%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM13,412,552$49.1M0.6%00.0%UnchangedHistory
AVIRAtea Pharmaceuticals, Inc.COM2,259,224$48.5M0.6%−850,000−27.3%ReducedHistory
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$46.1M0.6%–New–
CMAXCareMax, Inc.COM CL A3,320,000$42.8M0.6%+3,320,000NewHistory
DBVTDBV Technologies S.A.SPONSORED ADR7,695,505$42.0M0.5%00.0%UnchangedHistory
APLSApellis Pharmaceuticals, Inc.COM661,162$41.8M0.5%+661,162NewHistory
VRCAVerrica Pharmaceuticals Inc.COM3,610,412$40.8M0.5%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM2,537,019$39.4M0.5%+2,537,019New–
TMCITreace Medical Concepts, Inc.COM1,235,886$38.6M0.5%+1,235,886NewHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$37.6M0.5%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM553,908$37.4M0.5%+553,908NewHistory
VERUVeru Inc.COM4,451,342$35.9M0.5%00.0%UnchangedHistory
LONALeonaBio, Inc.COM3,425,916$35.1M0.5%00.0%UnchangedHistory
HCATHealth Catalyst, Inc.COM566,084$31.4M0.4%+60,000+11.9%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,678,973$31.3M0.4%+1,163,931+226.0%AddedHistory
DRNADicerna Pharmaceuticals IncCOM800,000$29.9M0.4%00.0%UnchangedHistory
BCABBioAtla, Inc.COM685,519$29.1M0.4%+685,519NewHistory
EXASExact Sciences CorpCOM233,523$29.0M0.4%−120,000−33.9%ReducedHistory
IMTXImmatics N.V.SHS2,500,000$29.0M0.4%00.0%UnchangedHistory
NARIInari Medical, Inc.Stock310,437$29.0M0.4%−254,676−45.1%ReducedHistory
ISEEIVERIC bio, Inc.COM4,585,512$28.9M0.4%00.0%UnchangedHistory
XLRNAcceleron Pharma IncCOM226,760$28.5M0.4%+226,760NewHistory
NUVBNuvation Bio Inc.COM CL A3,041,004$28.3M0.4%00.0%UnchangedHistory
ATECAlphatec Holdings, Inc.COM NEW1,800,180$27.6M0.4%00.0%UnchangedHistory
TVTXTravere Therapeutics, Inc.COM1,845,555$26.9M0.4%−1,452,864−44.0%ReducedHistory
LENZLENZ Therapeutics, Inc.COM875,093$26.9M0.3%+875,093NewHistory
Avidity Biosciences, Inc.05370A108COM1,079,028$26.7M0.3%−20,000−1.8%Reduced–
KODKodiak Sciences Inc.COM286,041$26.6M0.3%−102,967−26.5%ReducedHistory
ADMAAdma Biologics, Inc.COM16,584,802$26.5M0.3%00.0%UnchangedHistory
RGENRepligen CorpCOM132,500$26.4M0.3%+132,500NewHistory
ARWRArrowhead Pharmaceuticals, Inc.COM315,141$26.1M0.3%−94,200−23.0%ReducedHistory
LYRALyra Therapeutics, Inc.COM3,222,560$25.9M0.3%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM3,188,750$25.9M0.3%00.0%UnchangedHistory
PMVPPMV Pharmaceuticals, Inc.COM746,557$25.5M0.3%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM907,090$25.0M0.3%+907,090NewHistory
CLDXCelldex Therapeutics, Inc.COM NEW742,699$24.8M0.3%+742,699NewHistory
COLLCollegium Pharmaceutical, IncCOM978,277$23.1M0.3%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM685,000$23.0M0.3%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM671,978$22.6M0.3%00.0%UnchangedHistory
AGRXAgile Therapeutics IncCOM15,919,925$21.2M0.3%00.0%UnchangedHistory
YARWYarrow Bioscience, Inc.COM5,773,954$20.3M0.3%−1,000,000−14.8%ReducedHistory
ONCROncorus, Inc.COM1,463,599$20.2M0.3%−526,388−26.5%ReducedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$20.0M0.3%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS2,888,889$18.9M0.2%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock756,047$17.2M0.2%+756,047NewHistory
ONEM1Life Healthcare IncCOM516,044$17.1M0.2%−3,800−0.7%ReducedHistory
CM Life Sciences II Inc125842203UNIT 02/25/20281,250,000$16.8M0.2%00.0%Unchanged–
Catabasis Pharmaceuticals IN14875P206COM NEW7,687,185$16.2M0.2%+5,753,634+297.6%Added–
Nanostring Technologies Inc63009RAD1NOTE 2.625% 5/0–$16.2M0.2%–New–
IMCRImmunocore Holdings plcADS400,000$15.6M0.2%00.0%UnchangedHistory
Therapeutics Acquisition Cor88339T103COM CL A1,500,000$15.4M0.2%00.0%Unchanged–
NEPTFNeptune Wellness Solutions Inc.COM12,849,706$15.0M0.2%00.0%UnchangedHistory
ACRSAclaris Therapeutics, Inc.COM850,000$14.9M0.2%+200,000+30.8%AddedHistory
HYPRHyperfine, Inc.CL A SHS1,500,000$14.8M0.2%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$14.6M0.2%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM794,506$14.5M0.2%+794,506NewHistory
ADPTAdaptive Biotechnologies CorpCOM352,804$14.4M0.2%00.0%UnchangedHistory
VTRSViatris IncStock1,004,419$14.4M0.2%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM1,775,167$14.3M0.2%−175,000−9.0%ReducedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2021
SecurityClassPutsCalls
TDOCTeladoc Health, Inc.COM–$16.6M
RAPTRAPT Therapeutics, Inc.COM$83.0K–

Sold out since Q1 2021 (17)

Positions held at the end of Q1 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2021
SecurityClassShares in Q1 2021Value in Q1 2021% of portfolio in Q1 2021History
ALLOAllogene Therapeutics, Inc.COM1,143,790$40.4M0.5%History
ARNAArena Pharmaceuticals IncCOM NEW575,007$39.9M0.5%History
ACADAcadia Pharmaceuticals IncCOM1,410,305$36.4M0.5%History
FMTXForma Therapeutics Holdings, Inc.SHS1,250,000$35.0M0.5%History
CMPSCOMPASS Pathways plcSPONSORED ADS797,404$29.4M0.4%History
PCVXVaxcyte, Inc.COM850,000$16.8M0.2%History
SNDXSyndax Pharmaceuticals IncCOM270,000$6.04M0.1%History
VINCVincerx Pharma, Inc.COM NEW300,000$5.79M0.1%History
PHRPhreesia, Inc.COM100,000$5.21M0.1%History
Deerfield Healthcare Tech Ac244413209UNIT 07/16/2025300,000$3.93M0.1%–
TXMDTherapeuticsMD, Inc.COM2,750,000$3.69M<0.1%History
VRAYViewRay, Inc.COM751,748$3.27M<0.1%History
TLISTalis Biomedical CorpCOM250,000$3.21M<0.1%History
Vincerx Pharma, Inc.92731L114*W EXP 12/24/202300,000$1.21M<0.1%–
CVMCel Sci CorpCOM PAR NEW33,700$513.0K<0.1%History
SANASana Biotechnology, Inc.COM10,000$335.0K<0.1%History
Deerfield Healthcare Tech Ac244413100COM CL A20,000$242.0K<0.1%–