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Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2021

Holdings as of Jun 30, 2021, filed Aug 17, 2021. Long positions only; changes compare share counts with Q1 2021.

Institution overview
Positions
148
+12 vs. Q1 2021
Portfolio value
$7.69B
+$165.9M (+2.2%) vs. Q1 2021
Filed
Aug 17, 2021
AmendedSEC
Holdings of Perceptive Advisors LLC in Q2 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$283.0K<0.1%+60,000New–
PHVSPharvaris N.V.COM27,000$503.0K<0.1%00.0%UnchangedHistory
TCRRTCR2 Therapeutics Inc.COM30,753$505.0K<0.1%−282,547−90.2%ReducedHistory
TKNOAlpha Teknova, Inc.COM30,000$712.0K<0.1%+30,000NewHistory
PLXPPLx Pharma Winddown Corp.COM57,459$793.0K<0.1%−164,721−74.1%ReducedHistory
SC Health CorpG78516401*W EXP 99/99/999500,000$1.05M<0.1%00.0%Unchanged–
Butterfly Network, Inc.124155110*W EXP 05/27/202233,333$1.13M<0.1%00.0%Unchanged–
EIGREiger BioPharmaceuticals, Inc.COM139,890$1.19M<0.1%00.0%UnchangedHistory
RACEFerrari N.V.COM6,200$1.28M<0.1%00.0%UnchangedHistory
SRRASierra Oncology, Inc.COM NEW66,655$1.30M<0.1%00.0%UnchangedHistory
SGTXSigilon Therapeutics, Inc.COM125,000$1.34M<0.1%00.0%UnchangedHistory
MOTSMotus GI Holdings, Inc.COM1,800,542$1.87M<0.1%00.0%UnchangedHistory
Cerevel Therapeutics HLDNG I15678U102*W EXP 06/09/202133,066$1.91M<0.1%00.0%Unchanged–
KRROKorro Bio, Inc.COM222,222$2.21M<0.1%−1,891,439−89.5%ReducedHistory
GRTXGalera Therapeutics, Inc.COM254,664$2.50M<0.1%00.0%UnchangedHistory
SNCEScience 37 Holdings, Inc.COM300,000$3.00M<0.1%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM294,118$3.08M<0.1%+294,118NewHistory
CM Life Sciences Inc18978W109COM CL A227,000$3.18M<0.1%+100,000+78.7%Added–
RGNXREGENXBIO Inc.COM89,283$3.47M<0.1%+20,000+28.9%AddedHistory
AMWLAmerican Well CorpCL A290,000$3.65M<0.1%−65,000−18.3%ReducedHistory
MRUSMerus N.V.COM175,000$3.69M<0.1%00.0%UnchangedHistory
TARAProtara Therapeutics, Inc.COM STK421,641$4.11M0.1%−10.0%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.ORD SHS450,000$4.59M0.1%00.0%UnchangedHistory
Longview Acquisition Corp. II54319Q204UNIT 99/99/9999500,000$5.04M0.1%00.0%Unchanged–
PRTAProthena Corp Public Ltd CoSHS100,000$5.14M0.1%+100,000NewHistory
Consonance HFW Acquisition CG2445M129UNIT 99/99/9999500,000$5.20M0.1%00.0%Unchanged–
MREOMereo BioPharma Group plcSPON ADS1,696,068$5.38M0.1%−4,303,932−71.7%ReducedHistory
BCTG Acquisition Corp05492W103COM500,000$5.69M0.1%00.0%Unchanged–
AKYAAkoya Biosciences, Inc.COM300,000$5.80M0.1%+300,000NewHistory
PRVAPrivia Health Group, Inc.COM135,000$5.99M0.1%+135,000NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS320,440$6.79M0.1%−150,000−31.9%ReducedHistory
DRIODarioHealth Corp.COM NEW327,869$7.00M0.1%00.0%UnchangedHistory
SILKSilk Road Medical IncCOM147,133$7.04M0.1%−192,967−56.7%ReducedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS755,375$7.39M0.1%00.0%Unchanged–
PSTXPoseida Therapeutics, Inc.COM787,745$7.89M0.1%00.0%UnchangedHistory
PRVBProvention Bio, Inc.COM948,481$8.00M0.1%−1,903,577−66.7%ReducedHistory
FDMT4D Molecular Therapeutics, Inc.COM375,256$9.04M0.1%−69,622−15.6%ReducedHistory
CNCEConcert Pharmaceuticals, Inc.COM2,150,641$9.07M0.1%00.0%UnchangedHistory
TBIOTelesis Bio Inc.COM425,000$9.35M0.1%+425,000NewHistory
Summit Healthcre Acquistn CoG8566R128UNIT 06/03/20261,000,000$10.0M0.1%+1,000,000New–
RACBResearch Alliance Corp. IICOM CL A1,000,000$10.1M0.1%00.0%UnchangedHistory
CTMXCytomX Therapeutics, Inc.COM1,640,957$10.4M0.1%−513,017−23.8%ReducedHistory
BCLS Acquisition CorpG0904B105COM CL A1,000,000$10.5M0.1%00.0%Unchanged–
CVRXCVRx, Inc.COM440,000$12.3M0.2%+440,000NewHistory
ACCDAccolade, Inc.COM245,741$13.3M0.2%−100,000−28.9%ReducedHistory
CM Life Sciences III Inc125841205UNIT 04/30/20281,250,000$13.7M0.2%+1,250,000New–
HRMYHarmony Biosciences Holdings, Inc.COM491,332$13.9M0.2%+179,659+57.6%AddedHistory
CYPHCypherpunk Technologies Inc.COM8,476,496$13.9M0.2%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM1,775,167$14.3M0.2%−175,000−9.0%ReducedHistory
VTRSViatris IncStock1,004,419$14.4M0.2%00.0%UnchangedHistory
ADPTAdaptive Biotechnologies CorpCOM352,804$14.4M0.2%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM794,506$14.5M0.2%+794,506NewHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$14.6M0.2%00.0%UnchangedHistory
HYPRHyperfine, Inc.CL A SHS1,500,000$14.8M0.2%00.0%UnchangedHistory
ACRSAclaris Therapeutics, Inc.COM850,000$14.9M0.2%+200,000+30.8%AddedHistory
NEPTFNeptune Wellness Solutions Inc.COM12,849,706$15.0M0.2%00.0%UnchangedHistory
Therapeutics Acquisition Cor88339T103COM CL A1,500,000$15.4M0.2%00.0%Unchanged–
IMCRImmunocore Holdings plcADS400,000$15.6M0.2%00.0%UnchangedHistory
Nanostring Technologies Inc63009RAD1NOTE 2.625% 5/0–$16.2M0.2%–New–
Catabasis Pharmaceuticals IN14875P206COM NEW7,687,185$16.2M0.2%+5,753,634+297.6%Added–
CM Life Sciences II Inc125842203UNIT 02/25/20281,250,000$16.8M0.2%00.0%Unchanged–
ONEM1Life Healthcare IncCOM516,044$17.1M0.2%−3,800−0.7%ReducedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock756,047$17.2M0.2%+756,047NewHistory
VRNAVerona Pharma plcSPONSORED ADS2,888,889$18.9M0.2%00.0%UnchangedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$20.0M0.3%00.0%UnchangedHistory
ONCROncorus, Inc.COM1,463,599$20.2M0.3%−526,388−26.5%ReducedHistory
YARWYarrow Bioscience, Inc.COM5,773,954$20.3M0.3%−1,000,000−14.8%ReducedHistory
AGRXAgile Therapeutics IncCOM15,919,925$21.2M0.3%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM671,978$22.6M0.3%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM685,000$23.0M0.3%00.0%UnchangedHistory
COLLCollegium Pharmaceutical, IncCOM978,277$23.1M0.3%00.0%UnchangedHistory
CLDXCelldex Therapeutics, Inc.COM NEW742,699$24.8M0.3%+742,699NewHistory
INBXInhibrx Biosciences, Inc.COM907,090$25.0M0.3%+907,090NewHistory
PMVPPMV Pharmaceuticals, Inc.COM746,557$25.5M0.3%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM3,188,750$25.9M0.3%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM3,222,560$25.9M0.3%00.0%UnchangedHistory
ARWRArrowhead Pharmaceuticals, Inc.COM315,141$26.1M0.3%−94,200−23.0%ReducedHistory
RGENRepligen CorpCOM132,500$26.4M0.3%+132,500NewHistory
ADMAAdma Biologics, Inc.COM16,584,802$26.5M0.3%00.0%UnchangedHistory
KODKodiak Sciences Inc.COM286,041$26.6M0.3%−102,967−26.5%ReducedHistory
Avidity Biosciences, Inc.05370A108COM1,079,028$26.7M0.3%−20,000−1.8%Reduced–
LENZLENZ Therapeutics, Inc.COM875,093$26.9M0.3%+875,093NewHistory
TVTXTravere Therapeutics, Inc.COM1,845,555$26.9M0.4%−1,452,864−44.0%ReducedHistory
ATECAlphatec Holdings, Inc.COM NEW1,800,180$27.6M0.4%00.0%UnchangedHistory
NUVBNuvation Bio Inc.COM CL A3,041,004$28.3M0.4%00.0%UnchangedHistory
XLRNAcceleron Pharma IncCOM226,760$28.5M0.4%+226,760NewHistory
ISEEIVERIC bio, Inc.COM4,585,512$28.9M0.4%00.0%UnchangedHistory
NARIInari Medical, Inc.Stock310,437$29.0M0.4%−254,676−45.1%ReducedHistory
IMTXImmatics N.V.SHS2,500,000$29.0M0.4%00.0%UnchangedHistory
EXASExact Sciences CorpCOM233,523$29.0M0.4%−120,000−33.9%ReducedHistory
BCABBioAtla, Inc.COM685,519$29.1M0.4%+685,519NewHistory
DRNADicerna Pharmaceuticals IncCOM800,000$29.9M0.4%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM1,678,973$31.3M0.4%+1,163,931+226.0%AddedHistory
HCATHealth Catalyst, Inc.COM566,084$31.4M0.4%+60,000+11.9%AddedHistory
LONALeonaBio, Inc.COM3,425,916$35.1M0.5%00.0%UnchangedHistory
VERUVeru Inc.COM4,451,342$35.9M0.5%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM553,908$37.4M0.5%+553,908NewHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$37.6M0.5%00.0%UnchangedHistory
TMCITreace Medical Concepts, Inc.COM1,235,886$38.6M0.5%+1,235,886NewHistory
Rain Oncology Inc.75082Q105COM2,537,019$39.4M0.5%+2,537,019New–

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2021
SecurityClassPutsCalls
TDOCTeladoc Health, Inc.COM–$16.6M
RAPTRAPT Therapeutics, Inc.COM$83.0K–

Sold out since Q1 2021 (17)

Positions held at the end of Q1 2021 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2021
SecurityClassShares in Q1 2021Value in Q1 2021% of portfolio in Q1 2021History
ALLOAllogene Therapeutics, Inc.COM1,143,790$40.4M0.5%History
ARNAArena Pharmaceuticals IncCOM NEW575,007$39.9M0.5%History
ACADAcadia Pharmaceuticals IncCOM1,410,305$36.4M0.5%History
FMTXForma Therapeutics Holdings, Inc.SHS1,250,000$35.0M0.5%History
CMPSCOMPASS Pathways plcSPONSORED ADS797,404$29.4M0.4%History
PCVXVaxcyte, Inc.COM850,000$16.8M0.2%History
SNDXSyndax Pharmaceuticals IncCOM270,000$6.04M0.1%History
VINCVincerx Pharma, Inc.COM NEW300,000$5.79M0.1%History
PHRPhreesia, Inc.COM100,000$5.21M0.1%History
Deerfield Healthcare Tech Ac244413209UNIT 07/16/2025300,000$3.93M0.1%–
TXMDTherapeuticsMD, Inc.COM2,750,000$3.69M<0.1%History
VRAYViewRay, Inc.COM751,748$3.27M<0.1%History
TLISTalis Biomedical CorpCOM250,000$3.21M<0.1%History
Vincerx Pharma, Inc.92731L114*W EXP 12/24/202300,000$1.21M<0.1%–
CVMCel Sci CorpCOM PAR NEW33,700$513.0K<0.1%History
SANASana Biotechnology, Inc.COM10,000$335.0K<0.1%History
Deerfield Healthcare Tech Ac244413100COM CL A20,000$242.0K<0.1%–