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Artal Group S.A.

SEC CIK
0001053906
Latest filing
Aug 13, 2026

Holdings in Q3 2021

Holdings as of Sep 30, 2021, filed Nov 12, 2021. Long positions only; changes compare share counts with Q2 2021.

Institution overview
Positions
140
+2 vs. Q2 2021
Portfolio value
$4.07B
−$328.3M (−7.5%) vs. Q2 2021
Filed
Nov 12, 2021
SEC
Holdings of Artal Group S.A. in Q3 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
LXRXLexicon Pharmaceuticals, Inc.COM NEW71,178,364$342.4M8.4%00.0%UnchangedHistory
WWWW International, Inc.COM14,818,300$270.4M6.7%00.0%UnchangedHistory
ONCBeOne Medicines Ltd.ADR650,000$235.9M5.8%−200,000−23.5%ReducedHistory
MRTXMirati Therapeutics, Inc.COM1,200,000$212.3M5.2%+350,000+41.2%AddedHistory
ARGXArgenx SESPONSORED ADR577,308$174.3M4.3%+77,308+15.5%AddedHistory
XLRNAcceleron Pharma IncCOM1,000,000$172.1M4.2%−400,000−28.6%ReducedHistory
SEERSeer, Inc.COM CL A4,750,000$164.0M4.0%−838,366−15.0%ReducedHistory
ALNYAlnylam Pharmaceuticals, Inc.COM700,000$132.2M3.3%−50,000−6.7%ReducedHistory
MORFMorphic Holding, Inc.COM1,585,049$89.8M2.2%−234,137−12.9%ReducedHistory
IGMSIGM Biosciences, Inc.COM1,350,000$88.8M2.2%+250,000+22.7%AddedHistory
FATEFate Therapeutics IncCOM1,450,000$85.9M2.1%+100,000+7.4%AddedHistory
RUBYRubius Therapeutics, Inc.COM4,155,625$74.3M1.8%−478,166−10.3%ReducedHistory
GBIOGeneration Bio Co.COM2,814,191$70.6M1.7%00.0%UnchangedHistory
ERASErasca, Inc.COM3,172,221$67.3M1.7%+3,172,221NewHistory
SRRKScholar Rock Holding CorpCOM1,950,000$64.4M1.6%−50,000−2.5%ReducedHistory
FOLDAmicus Therapeutics, Inc.COM6,696,955$64.0M1.6%+2,946,955+78.6%AddedHistory
SGENSeagen Inc.COM375,000$63.7M1.6%+375,000NewHistory
NBPNovaBridge BiosciencesSPONSORED ADS825,000$59.8M1.5%+75,000+10.0%AddedHistory
KLRSKalaris Therapeutics, Inc.COM2,323,371$58.2M1.4%00.0%UnchangedHistory
CERECerevel Therapeutics Holdings, Inc.COM1,800,000$53.1M1.3%−200,000−10.0%ReducedHistory
CYTKCytokinetics IncCOM NEW1,300,000$46.5M1.1%+800,000+160.0%AddedHistory
SAGESage Therapeutics, Inc.COM1,000,000$44.3M1.1%00.0%UnchangedHistory
OMGAOmega Therapeutics, Inc.COMMON STOCK2,273,530$42.9M1.1%+2,273,530NewHistory
SDGRSchrodinger, Inc.COM700,000$38.3M0.9%−97,445−12.2%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM600,000$38.1M0.9%+100,000+20.0%AddedHistory
ALXOAlx Oncology Holdings IncCOM500,000$36.9M0.9%00.0%UnchangedHistory
NTLAIntellia Therapeutics, Inc.COM275,000$36.9M0.9%+25,000+10.0%AddedHistory
Bellus Health Inc New07987C204COM NEW5,250,000$32.2M0.8%+500,000+10.5%Added–
GOSSGossamer Bio, Inc.COM2,358,968$29.7M0.7%00.0%UnchangedHistory
AGENAgenus IncCOM NEW5,500,000$28.9M0.7%−500,000−8.3%ReducedHistory
TRMLTourmaline Bio, Inc.COM2,064,262$28.0M0.7%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM1,317,954$27.6M0.7%00.0%UnchangedHistory
ATRAAtara Biotherapeutics, Inc.COM1,500,000$26.9M0.7%00.0%UnchangedHistory
ITOSiTeos Therapeutics, Inc.COM994,047$26.8M0.7%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM900,000$26.7M0.7%00.0%UnchangedHistory
TGTXTG Therapeutics, Inc.COM800,000$26.6M0.7%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM1,500,000$26.6M0.7%+1,500,000NewHistory
KRYSKrystal Biotech, Inc.COM500,000$26.1M0.6%00.0%UnchangedHistory
DNLIDenali Therapeutics Inc.COM500,000$25.2M0.6%00.0%UnchangedHistory
FHTXFoghorn Therapeutics Inc.COM1,720,720$24.0M0.6%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM400,000$23.5M0.6%+150,000+60.0%AddedHistory
TPTXTurning Point Therapeutics, Inc.COM350,000$23.3M0.6%00.0%UnchangedHistory
FMTXForma Therapeutics Holdings, Inc.SHS1,000,000$23.2M0.6%00.0%UnchangedHistory
SQZSQZ Biotechnologies CoCOM1,606,309$23.2M0.6%00.0%UnchangedHistory
OTLYOatly Group ABSPONSORED ADS1,500,000$22.7M0.6%00.0%UnchangedHistory
PRAXPraxis Precision Medicines, Inc.COM1,200,000$22.2M0.5%00.0%UnchangedHistory
AUPHAurinia Pharmaceuticals Inc.COM1,000,000$22.1M0.5%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,050,000$19.7M0.5%+450,000+75.0%AddedHistory
IMAImageneBio, Inc.COM1,549,513$19.6M0.5%00.0%UnchangedHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,040,882$19.4M0.5%00.0%UnchangedHistory
VERVVerve Therapeutics, Inc.COM400,000$18.8M0.5%−100,000−20.0%ReducedHistory
ALBOAlbireo Pharma, Inc.COM600,000$18.7M0.5%00.0%UnchangedHistory
NEXINexImmune, Inc.COM1,200,000$18.2M0.4%00.0%UnchangedHistory
NGNovagold Resources IncCOM NEW2,600,000$17.9M0.4%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS2,255,375$17.6M0.4%00.0%Unchanged–
RNACCartesian Therapeutics, Inc.COM4,000,000$16.6M0.4%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM4,000,000$16.0M0.4%+1,000,000+33.3%AddedHistory
BABAAlibaba Group Holding LtdADR100,000$14.8M0.4%+100,000NewHistory
RPTXRepare Therapeutics Inc.COM550,000$14.4M0.4%00.0%UnchangedHistory
ADAGAdagene Inc.ADS1,000,000$14.4M0.4%00.0%UnchangedHistory
APTXAptinyx Inc.COM6,116,493$14.3M0.4%00.0%UnchangedHistory
DRNADicerna Pharmaceuticals IncCOM700,000$14.1M0.3%−100,000−12.5%ReducedHistory
BDTXBlack Diamond Therapeutics, Inc.COM1,646,517$13.9M0.3%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM450,000$13.1M0.3%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM400,000$12.6M0.3%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM250,000$11.7M0.3%−25,000−9.1%ReducedHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS850,000$11.5M0.3%00.0%UnchangedHistory
LENZLENZ Therapeutics, Inc.COM700,000$11.5M0.3%00.0%UnchangedHistory
YMABY-mAbs Therapeutics, Inc.COM400,000$11.4M0.3%00.0%UnchangedHistory
MRNSMarinus Pharmaceuticals, Inc.COM NEW1,000,000$11.4M0.3%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,000,000$11.4M0.3%00.0%UnchangedHistory
MRSNMersana Therapeutics, Inc.COM1,200,000$11.3M0.3%00.0%UnchangedHistory
LYELLyell Immunopharma, Inc.COM700,000$10.4M0.3%00.0%UnchangedHistory
BPMCBlueprint Medicines CorpCOM100,000$10.3M0.3%00.0%UnchangedHistory
CRISCuris IncCOM NEW1,300,000$10.2M0.3%00.0%UnchangedHistory
CRBUCaribou Biosciences, Inc.COM405,347$9.68M0.2%+405,347NewHistory
SPROSpero Therapeutics, Inc.COM500,000$9.21M0.2%00.0%UnchangedHistory
SANASana Biotechnology, Inc.COM400,000$9.01M0.2%00.0%UnchangedHistory
SYRSSyros Pharmaceuticals, Inc.COM2,000,000$8.94M0.2%+300,000+17.6%AddedHistory
VORVor Biopharma Inc.COM550,000$8.62M0.2%00.0%UnchangedHistory
KRSAKorsana Biosciences, Inc.COM2,779,122$8.53M0.2%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM525,000$8.53M0.2%00.0%UnchangedHistory
OVIDOvid Therapeutics Inc.COM2,500,000$8.40M0.2%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM400,000$8.36M0.2%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM1,045,000$8.31M0.2%00.0%UnchangedHistory
TILInstil Bio, Inc.COM450,000$8.04M0.2%00.0%UnchangedHistory
IQiQIYI, Inc.SPONSORED ADS1,000,000$8.03M0.2%00.0%UnchangedHistory
HARPHarpoon Therapeutics, Inc.COM1,000,000$7.90M0.2%00.0%UnchangedHistory
IMCRImmunocore Holdings plcADS200,000$7.41M0.2%00.0%UnchangedHistory
Omega Alpha SpacG6749V107CL A750,000$7.30M0.2%00.0%Unchanged–
OLMAOlema Pharmaceuticals, Inc.COM260,500$7.18M0.2%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM3,000,000$7.17M0.2%+750,000+33.3%AddedHistory
EVLOEvelo Biosciences, Inc.COM1,000,000$7.04M0.2%00.0%UnchangedHistory
ACIUAC Immune SASHS1,000,000$6.71M0.2%00.0%UnchangedHistory
APLTApplied Therapeutics, Inc.COM400,000$6.64M0.2%00.0%UnchangedHistory
ADVMAdverum Biotechnologies, Inc.COM3,000,000$6.51M0.2%00.0%UnchangedHistory
TCRRTCR2 Therapeutics Inc.COM750,000$6.38M0.2%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM250,000$6.36M0.2%00.0%UnchangedHistory
ALPNAlpine Immune Sciences, Inc.COM593,030$6.33M0.2%00.0%UnchangedHistory
IMUXImmunic, Inc.COM700,000$6.20M0.2%00.0%UnchangedHistory

Options (6)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Artal Group S.A. in Q3 2021
SecurityClassPutsCalls
CCitigroup IncStock–$140.4M
FCXFreeport-McMoran IncStock–$113.9M
BMYBristol Myers Squibb CoStock–$59.2M
MRKMerck & Co., Inc.Stock–$37.6M
VRTXVertex Pharmaceuticals IncStock–$36.3M
INTCIntel CorpStock–$16.0M

Sold out since Q2 2021 (15)

Positions held at the end of Q2 2021 that are gone from this filing.

Positions of Artal Group S.A. sold out since Q2 2021
SecurityClassShares in Q2 2021Value in Q2 2021% of portfolio in Q2 2021History
BHVNBiohaven Ltd.COM400,000$38.8M0.9%History
Trillium Therapeutics Inc.89620X506COM NEW2,500,000$24.3M0.6%–
CARAvis Budget Group, Inc.COM300,000$23.4M0.5%History
DLOdLocal LtdCLASS A COM295,000$15.5M0.4%History
LFSTLifeStance Health Group, Inc.COM500,000$13.9M0.3%History
Translate Bio, Inc.89374L104COM500,000$13.8M0.3%–
AGLagilon health, inc.COM300,000$12.2M0.3%History
NEUENeueHealth, Inc.COM305,555$5.24M0.1%History
ALDXAldeyra Therapeutics, Inc.COM431,894$4.89M0.1%History
MCRBSeres Therapeutics, Inc.COM200,000$4.77M0.1%History
Paramount Global92556H206CL B75,000$3.39M0.1%–
MOLNMolecular Partners AGADS100,000$2.05M<0.1%History
Chiasma, Inc16706W102COM380,000$1.80M<0.1%–
Cerevel Therapeutics HLDNG I15678U102*W EXP 06/09/20279,600$1.15M<0.1%–
LULufax Holding LtdADS REP SHS CL A50,000$565.0K<0.1%History