Prime Medicine, Inc.
PRME- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
近 90 天，Prime Medicine, Inc. 沒有內部人公開市場買賣的申報；2026 年第 2 季末有 187 家機構在 13F 申報持有，市值合計 $3.93 億；大師中只有方舟投資持有。
2025 年第 4 季 13F 持有人
Prime Medicine, Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 183
- 較 2025 年第 3 季 +18 家
- 持有股數
- 9,699 萬
- 較 2025 年第 3 季 +643.1 萬 (+7.1%)
- 總市值
- $3.36 億
- 較 2025 年第 3 季 −$1.65 億 (−32.9%)
- 新進機構
- 44
- 另有 66 家加碼
- 清倉機構
- 26
- 另有 40 家減碼
另有 2 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 PRME 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 187 | $3.93 億 |
| 2026 年第 1 季 | 192 | $3.43 億 |
| 2025 年第 4 季 | 183 | $3.36 億 |
| 2025 年第 3 季 | 167 | $5.12 億 |
| 2025 年第 2 季 | 121 | $1.45 億 |
| 2025 年第 1 季 | 125 | $1.20 億 |
| 2024 年第 4 季 | 132 | $1.88 億 |
| 2024 年第 3 季 | 116 | $2.66 億 |
| 2024 年第 2 季 | 122 | $3.54 億 |
| 2024 年第 1 季 | 115 | $4.67 億 |
| 2023 年第 4 季 | 105 | $4.31 億 |
| 2023 年第 3 季 | 83 | $4.72 億 |
| 2023 年第 2 季 | 79 | $6.76 億 |
| 2023 年第 1 季 | 76 | $5.12 億 |
| 2022 年第 4 季 | 66 | $7.68 億 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2025 年第 4 季持有機構
每家機構持有 Prime Medicine, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Alphabet Inc. | 16,562,498 | $5,747 萬 | 2.23% | 00.0% | 不變 |
| BlackRock, Inc. | 8,268,843 | $2,869 萬 | 0.00% | +2,617,984+46.3% | 加碼 |
| Vanguard Group Inc | 6,467,872 | $2,244 萬 | 0.00% | +1,546,007+31.4% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 5,995,183 | $2,080 萬 | 0.01% | −3,221,914−35.0% | 減碼 |
| ARK Investment Management LLC大師方舟投資 | 5,368,526 | $1,863 萬 | 0.12% | −109,325−2.0% | 減碼 |
| State Street Corp | 5,095,510 | $1,768 萬 | 0.00% | +3,798,884+293.0% | 加碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,245,506 | $1,126 萬 | 0.01% | −384,418−10.6% | 減碼 |
| Nikko Asset Management Americas, Inc. | 3,245,506 | $1,120 萬 | 0.13% | −384,418−10.6% | 減碼 |
| Casdin Capital, LLC | 3,167,175 | $1,099 萬 | 0.68% | 00.0% | 不變 |
| Balyasny Asset Management LLC | 3,124,362 | $1,084 萬 | 0.02% | +3,076,489+6,426.4% | 加碼 |
| Woodline Partners LP | 3,002,844 | $1,042 萬 | 0.04% | +3620.0% | 加碼 |
| Geode Capital Management, LLC | 2,628,429 | $912.3 萬 | 0.00% | +861,533+48.8% | 加碼 |
| UBS Group AG | 2,440,583 | $846.9 萬 | 0.00% | +2,135,810+700.8% | 加碼 |
| FMR LLC | 2,176,646 | $755.3 萬 | 0.00% | −636,429−22.6% | 減碼 |
| MWG Caph Ltd | 1,792,210 | $621.9 萬 | 8.59% | +1,792,210 | 新進 |
| Goldman Sachs Group Inc | 1,755,768 | $609.3 萬 | 0.00% | +1,345,032+327.5% | 加碼 |
| Two Sigma Investments, LP | 1,629,324 | $565.4 萬 | 0.01% | +1,181,657+264.0% | 加碼 |
| D. E. Shaw & Co., Inc. | 1,551,369 | $538.3 萬 | 0.00% | −664,483−30.0% | 減碼 |
| Farallon Capital Management, L.L.C. | 1,240,843 | $430.6 萬 | 0.02% | −3,509,157−73.9% | 減碼 |
| Susquehanna International Group, LLP | 1,176,727 | $408.3 萬 | 0.01% | +592,303+101.3% | 加碼 |
| Morgan Stanley | 1,169,898 | $406.0 萬 | 0.00% | +438,894+60.0% | 加碼 |
| Renaissance Technologies LLC | 1,149,159 | $398.8 萬 | 0.01% | +14,489+1.3% | 加碼 |
| Charles Schwab Investment Management Inc | 936,815 | $325.1 萬 | 0.00% | +363,657+63.4% | 加碼 |
| Northern Trust Corp | 842,153 | $292.2 萬 | 0.00% | +234,164+38.5% | 加碼 |
| Greenwich Wealth Management LLC | 740,001 | $256.8 萬 | 0.11% | +20,000+2.8% | 加碼 |
| HRT Financial LP | 655,351 | $227.4 萬 | 0.01% | +433,887+195.9% | 加碼 |
| Bank of America Corp | 648,012 | $224.9 萬 | 0.00% | +537,170+484.6% | 加碼 |
| Point72 Asset Management, L.P. | 551,030 | $191.2 萬 | 0.00% | +551,030 | 新進 |
| Moore Capital Management, LP | 500,000 | $173.5 萬 | 0.04% | 00.0% | 不變 |
| JPMorgan Chase & Co | 435,710 | $151.2 萬 | 0.00% | +392,321+904.2% | 加碼 |
| AQR Capital Management LLC | 415,821 | $144.3 萬 | 0.00% | +1,610+0.4% | 加碼 |
| HighTower Advisors, LLC | 400,110 | $138.8 萬 | 0.00% | +66,355+19.9% | 加碼 |
| Two Sigma Advisers, LP | 383,500 | $133.1 萬 | 0.00% | +383,500 | 新進 |
| Barclays PLC | 363,826 | $126.2 萬 | 0.00% | +247,926+213.9% | 加碼 |
| Bollard Group LLC | 361,136 | $125.3 萬 | 0.03% | 00.0% | 不變 |
| Wells Fargo & Company | 294,496 | $102.2 萬 | 0.00% | +97,482+49.5% | 加碼 |
| Verition Fund Management LLC | 290,983 | $101.0 萬 | 0.01% | +290,983 | 新進 |
| Nuveen, LLC | 251,636 | $87.3 萬 | 0.00% | +25,793+11.4% | 加碼 |
| Wellington Management Group LLP | 248,227 | $86.1 萬 | 0.00% | +42,902+20.9% | 加碼 |
| Bank of New York Mellon Corp | 246,770 | $85.6 萬 | 0.00% | +49,041+24.8% | 加碼 |
| Chelsea Counsel Co | 227,000 | $78.8 萬 | 0.34% | +18,790+9.0% | 加碼 |
| Dark Forest Capital Management LP | 225,859 | $78.4 萬 | 0.04% | +225,859 | 新進 |
| Squarepoint Ops LLC | 218,042 | $75.7 萬 | 0.00% | +178,441+450.6% | 加碼 |
| Green Alpha Advisors, LLC | 190,883 | $66.2 萬 | 0.61% | +530+0.3% | 加碼 |
| Rafferty Asset Management, LLC | 187,711 | $65.1 萬 | 0.00% | +187,711 | 新進 |
| Davy Global Fund Management Ltd | 178,519 | $61.9 萬 | 0.04% | +57,746+47.8% | 加碼 |
| Jump Financial, LLC | 171,931 | $59.7 萬 | 0.01% | +171,931 | 新進 |
| Swiss National Bank | 170,100 | $59.0 萬 | 0.00% | +170,100 | 新進 |
| Deutsche Bank AG | 147,943 | $51.3 萬 | 0.00% | +15,174+11.4% | 加碼 |
| Bridgeway Capital Management, LLC | 134,800 | $46.8 萬 | 0.01% | −30,000−18.2% | 減碼 |
| Keystone Financial Group | 129,665 | $45.0 萬 | 0.03% | +58,810+83.0% | 加碼 |
| Rockefeller Capital Management L.P. | 121,391 | $42.1 萬 | 0.00% | +120,252+10,557.7% | 加碼 |
| Steward Partners Investment Advisory, LLC | 118,406 | $41.1 萬 | 0.00% | −7,981−6.3% | 減碼 |
| FIL Ltd | 115,602 | $40.1 萬 | 0.00% | −727−0.6% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 115,060 | $39.9 萬 | 0.00% | −5,363−4.5% | 減碼 |
| Graham Capital Management, L.P. | 114,680 | $39.8 萬 | 0.01% | +114,680 | 新進 |
| Citadel Advisors LLC | 112,870 | $39.2 萬 | 0.00% | −787,272−87.5% | 減碼 |
| Alliancebernstein L.P. | 108,690 | $37.7 萬 | 0.00% | 00.0% | 不變 |
| Rhumbline Advisers | 108,409 | $37.6 萬 | 0.00% | −1,378−1.3% | 減碼 |
| Price T Rowe Associates Inc | 104,553 | $36.3 萬 | 0.00% | +30,051+40.3% | 加碼 |
| Group One Trading, L.P. | 103,213 | $35.8 萬 | 0.01% | +103,213 | 新進 |
| UBS Asset Management Americas Inc | 99,100 | $34.4 萬 | 0.00% | +99,100 | 新進 |
| Virtu Financial LLC | 94,778 | $32.9 萬 | 0.01% | +82,948+701.2% | 加碼 |
| Qube Research & Technologies Ltd | 94,670 | $32.9 萬 | 0.00% | +94,670 | 新進 |
| TD Asset Management Inc | 94,148 | $32.7 萬 | 0.00% | −86,900−48.0% | 減碼 |
| California State Teachers Retirement System | 86,929 | $30.2 萬 | 0.00% | +83,275+2,279.0% | 加碼 |
| Palumbo Wealth Management LLC | 85,539 | $29.7 萬 | 0.07% | −6,996−7.6% | 減碼 |
| Dimensional Fund Advisors LP | 84,054 | $29.2 萬 | 0.00% | +84,054 | 新進 |
| Legal & General Group Plc | 80,749 | $28.0 萬 | 0.00% | +73,998+1,096.1% | 加碼 |
| XTX Topco Ltd | 72,935 | $25.3 萬 | 0.01% | +24,710+51.2% | 加碼 |
| Profund Advisors LLC | 69,605 | $24.2 萬 | 0.01% | +69,605 | 新進 |
| Virtus Investment Advisers, Inc. | 64,886 | $22.5 萬 | 0.06% | +64,886 | 新進 |
| Janus Henderson Group PLC | 60,900 | $21.0 萬 | 0.00% | +60,900 | 新進 |
| Engineers Gate Manager LP | 60,490 | $21.0 萬 | 0.00% | +4,893+8.8% | 加碼 |
| Wiley Bros.-Aintree Capital, LLC | 60,352 | $20.9 萬 | 0.00% | +48,504+409.4% | 加碼 |
| MetLife Investment Management | 57,570 | $20.0 萬 | 0.00% | +14,573+33.9% | 加碼 |
| Invesco Ltd. | 56,779 | $19.7 萬 | 0.00% | −705,299−92.5% | 減碼 |
| Brevan Howard Capital Management LP | 56,088 | $19.5 萬 | 0.00% | −6,154−9.9% | 減碼 |
| Ameriprise Financial Inc | 54,082 | $18.8 萬 | 0.00% | −7,490−12.2% | 減碼 |
| Quadrature Capital Ltd | 52,866 | $18.3 萬 | 0.00% | +42,684+419.2% | 加碼 |
| Millennium Management LLC | 51,335 | $17.8 萬 | 0.00% | −1,367,128−96.4% | 減碼 |
| Citigroup Inc | 51,229 | $17.8 萬 | 0.00% | +46,078+894.5% | 加碼 |
| Toroso Investments, LLC | 50,244 | $17.4 萬 | 0.00% | +50,244 | 新進 |
| Walleye Capital LLC | 46,139 | $16.0 萬 | 0.00% | +46,139 | 新進 |
| Mutual Advisors, LLC | 45,200 | $15.7 萬 | 0.00% | 00.0% | 不變 |
| Elevate Capital Advisors, LLC | 42,666 | $14.8 萬 | 0.10% | +42,666 | 新進 |
| IvyRock Asset Management (HK) Ltd | 41,800 | $14.5 萬 | 0.08% | 00.0% | 不變 |
| Jones Financial Companies LLLP | 40,403 | $14.0 萬 | 0.00% | +30,828+322.0% | 加碼 |
| CI Private Wealth, LLC | 38,777 | $13.5 萬 | 0.00% | 00.0% | 不變 |
| Caitong International Asset Management Co., Ltd | 38,696 | $13.4 萬 | 0.03% | +38,696 | 新進 |
| Gsa Capital Partners LLP | 38,510 | $13.4 萬 | 0.01% | +38,510 | 新進 |
| Ieq Capital, LLC | 37,136 | $12.9 萬 | 0.00% | +469+1.3% | 加碼 |
| Mariner, LLC | 36,290 | $12.6 萬 | 0.00% | +18,071+99.2% | 加碼 |
| Polymer Capital Management (US) LLC | 35,981 | $12.5 萬 | 0.02% | +15,190+73.1% | 加碼 |
| Intech Investment Management LLC | 35,036 | $12.2 萬 | 0.00% | +11,808+50.8% | 加碼 |
| Central Trust Co | 34,995 | $12.1 萬 | 0.00% | +34,995 | 新進 |
| Commonwealth Equity Services, LLC | 34,399 | $11.9 萬 | 0.00% | −28,769−45.5% | 減碼 |
| Axq Capital, LP | 33,405 | $11.6 萬 | 0.03% | −11,413−25.5% | 減碼 |
| LPL Financial LLC | 32,924 | $11.4 萬 | 0.00% | +1,885+6.1% | 加碼 |
| Envestnet Asset Management Inc | 32,576 | $11.3 萬 | 0.00% | +32,576 | 新進 |