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Zai Lab Ltd

ZLAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001704292

In the last 90 days, Zai Lab Ltd insiders filed 1 open-market purchase and 7 sales; 92 institutions reported holding it in 13F filings for Q2 2026, worth $822.8M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Zai Lab Ltd as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
−11 vs. Q3 2025
Shares held
28.9M
−6.17M (−17.6%) vs. Q3 2025
Total value
$510.5M
−$679.4M (−57.1%) vs. Q3 2025
New holders
33
36 more added
Sold out
44
40 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZLAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 126 institutions
Q1 2021: 222 institutionsQ2 2021: 234 institutionsQ3 2021: 228 institutionsQ4 2021: 207 institutionsQ1 2022: 176 institutionsQ2 2022: 166 institutionsQ3 2022: 171 institutionsQ4 2022: 167 institutionsQ1 2023: 161 institutionsQ2 2023: 138 institutionsQ3 2023: 122 institutionsQ4 2023: 124 institutionsQ1 2024: 117 institutionsQ2 2024: 105 institutionsQ3 2024: 104 institutionsQ4 2024: 131 institutionsQ1 2025: 160 institutionsQ2 2025: 156 institutionsQ3 2025: 138 institutionsQ4 2025: 126 institutionsQ1 2026: 99 institutionsQ2 2026: 92 institutions
Value heldQ4 2025: $510.5M
Q1 2021: $7.24BQ2 2021: $11.0BQ3 2021: $6.76BQ4 2021: $4.07BQ1 2022: $2.74BQ2 2022: $2.11BQ3 2022: $2.11BQ4 2022: $1.79BQ1 2023: $1.85BQ2 2023: $1.18BQ3 2023: $954.6MQ4 2023: $1.13BQ1 2024: $668.9MQ2 2024: $707.8MQ3 2024: $1.10BQ4 2024: $1.48BQ1 2025: $1.97BQ2 2025: $1.49BQ3 2025: $1.19BQ4 2025: $510.5MQ1 2026: $530.9MQ2 2026: $822.8M
Institutions holding ZLAB and their total value by quarter
QuarterHoldersValue
Q2 202692$822.8M
Q1 202699$530.9M
Q4 2025126$510.5M
Q3 2025138$1.19B
Q2 2025156$1.49B
Q1 2025160$1.97B
Q4 2024131$1.48B
Q3 2024104$1.10B
Q2 2024105$707.8M
Q1 2024117$668.9M
Q4 2023124$1.13B
Q3 2023122$954.6M
Q2 2023138$1.18B
Q1 2023161$1.85B
Q4 2022167$1.79B
Q3 2022171$2.11B
Q2 2022166$2.11B
Q1 2022176$2.74B
Q4 2021207$4.07B
Q3 2021228$6.76B
Q2 2021234$11.0B
Q1 2021222$7.24B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Zai Lab Ltd; share changes are against Q3 2025.

Institutions holding ZLAB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP6,959,032$122.8M1.23%+4,667,660+203.7%Added
Frazier Life Sciences Management, L.P.1,902,320$33.6M0.90%+275,000+16.9%Added
Clearbridge Investments, LLC1,808,035$31.9M0.03%−1,711,302−48.6%Reduced
UBS Group AG1,782,252$31.4M0.01%+1,475,698+481.4%Added
Citadel Advisors LLC1,687,846$29.8M0.02%+700,803+71.0%Added
FMR LLC1,440,406$25.4M0.00%−3,261,305−69.4%Reduced
Bamco Inc1,418,005$25.0M0.07%+46,762+3.4%Added
ADAR1 Capital Management, LLC1,246,520$22.0M1.64%+377,740+43.5%Added
Rock Springs Capital Management LP811,546$14.3M0.73%+20,353+2.6%Added
Wellington Management Group LLP752,858$13.3M0.00%−965,597−56.2%Reduced
BlackRock, Inc.635,213$11.2M0.00%+161,650+34.1%Added
Price T Rowe Associates Inc602,954$10.6M0.00%−345,717−36.4%Reduced
C WorldWide Group Holding A/S510,000$9.00M0.16%00.0%Unchanged
B Group, Inc.400,000$7.06M5.23%00.0%Unchanged
Bank of America Corp388,769$6.86M0.00%+246,395+173.1%Added
Legal & General Group Plc387,800$6.84M0.00%+5,341+1.4%Added
Jane Street Group, LLC382,062$6.74M0.01%+382,062New
Walleye Capital LLC373,399$6.59M0.04%+373,399New
Schroder Investment Management Group299,844$5.29M0.00%+142,783+90.9%Added
JPMorgan Chase & Co293,703$5.18M0.00%+274,889+1,461.1%Added
Morgan Stanley289,705$5.11M0.00%+169,825+141.7%Added
Nan Fung Trinity (HK) Ltd269,975$4.76M0.38%00.0%Unchanged
D. E. Shaw & Co., Inc.238,609$4.21M0.00%+204,319+595.9%Added
Marshall Wace, LLP231,802$4.09M0.00%+170,400+277.5%Added
Hennion & Walsh Asset Management, Inc.204,982$3.62M0.12%+44,945+28.1%Added
XY Capital Ltd202,304$3.57M3.63%+202,304New
Superstring Capital Management LP196,853$3.47M1.86%−3,775−1.9%Reduced
Ameriprise Financial Inc181,133$3.20M0.00%+181,133New
Dimensional Fund Advisors LP173,946$3.07M0.00%+127,261+272.6%Added
Campbell & CO Investment Adviser LLC170,117$3.00M0.14%+170,117New
NEXTBio Capital Management LP163,362$2.88M1.69%+163,362New
Envestnet Asset Management Inc151,318$2.67M0.00%−100,712−40.0%Reduced
Goldman Sachs Group Inc149,434$2.64M0.00%+67,253+81.8%Added
State Street Corp136,428$2.41M0.00%+90+0.1%Added
Privium Fund Management B.V.132,189$2.33M0.43%00.0%Unchanged
Qube Research & Technologies Ltd107,651$1.90M0.00%+107,651New
Mirae Asset Global Investments Co., Ltd.103,118$1.82M0.01%−1,981−1.9%Reduced
Principal Financial Group Inc101,782$1.80M0.00%−2,503−2.4%Reduced
DCF Advisers, LLC97,500$1.72M0.57%+5,500+6.0%Added
Northern Trust Corp96,442$1.70M0.00%−49,561−33.9%Reduced
Wells Fargo & Company93,140$1.64M0.00%−81,992−46.8%Reduced
Raymond James Financial Inc92,837$1.64M0.00%−91,929−49.8%Reduced
Alps Advisors Inc92,107$1.62M0.01%+39,491+75.1%Added
Hudson Bay Capital Management LP90,000$1.59M0.01%+90,000New
TD Asset Management Inc86,640$1.53M0.00%−34,888−28.7%Reduced
HRT Financial LP83,793$1.48M0.00%+57,025+213.0%Added
NEOS Investment Management LLC75,165$1.33M0.01%+13,098+21.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.65,814$1.16M0.00%+65,814New
Long Corridor Asset Management Ltd65,800$1.16M0.08%00.0%Unchanged
Susquehanna International Group, LLP56,895$1.00M0.00%+56,895New
Manufacturers Life Insurance Company, The46,935$827.5K0.00%−22,220−32.1%Reduced
Schonfeld Strategic Advisors LLC40,005$705.7K0.00%+40,005New
Virtus Investment Advisers, Inc.38,457$678.4K0.18%+28,129+272.4%Added
WealthPlan Investment Management, LLC36,761$648.5K0.04%00.0%Unchanged
DekaBank Deutsche Girozentrale36,648$647.0K0.00%00.0%Unchanged
MML Investors Services, LLC34,421$607.2K0.00%−11,063−24.3%Reduced
LPL Financial LLC31,114$548.9K0.00%−53,996−63.4%Reduced
DRW Securities, LLC30,862$544.4K0.04%+30,862New
Invesco Ltd.30,594$539.7K0.00%−7,960−20.6%Reduced
Two Sigma Investments, LP29,523$520.8K0.00%+29,523New
Geode Capital Management, LLC23,879$421.2K0.00%−26,697−52.8%Reduced
Bank of Montreal22,099$389.8K0.00%−9,940−31.0%Reduced
Brinker Capital Investments, LLC20,849$367.8K0.00%−27,668−57.0%Reduced
Group One Trading, L.P.19,032$335.7K0.01%+19,032New
US Bancorp17,771$313.5K0.00%−6,991−28.2%Reduced
Marks Group Wealth Management, Inc16,278$287.1K0.03%−245−1.5%Reduced
Legacy Wealth Asset Management, LLC15,903$280.5K0.07%−6,237−28.2%Reduced
Headlands Technologies LLC15,846$279.5K0.02%+15,846New
Erste Asset Management GmbH15,100$269.1K0.00%00.0%Unchanged
IvyRock Asset Management (HK) Ltd14,979$264.2K0.14%−79,900−84.2%Reduced
Royal Bank of Canada14,757$260.0K0.00%−6,614−30.9%Reduced
ExodusPoint Capital Management, LP13,618$240.2K0.00%+13,618New
Persistent Asset Partners Ltd12,339$217.7K0.10%+12,339New
Oppenheimer Asset Management Inc.10,608$187.1K0.00%−11,126−51.2%Reduced
Virtu Financial LLC10,551$186.0K0.01%+10,551New
SG Americas Securities, LLC10,396$183.0K0.00%+642+6.6%Added
LMR Partners LLP10,320$182.0K0.00%−122,348−92.2%Reduced
Quantinno Capital Management LP10,085$177.9K0.00%+1,452+16.8%Added
China Universal Asset Management Co., Ltd.6,380$112.5K0.01%−2,000−23.9%Reduced
Citigroup Inc5,151$90.9K0.00%−3,115−37.7%Reduced
Basecamp Wealth Advisors LLC3,227$56.9K0.01%+3,227New
Storebrand Asset Management AS2,580$45.5K0.00%00.0%Unchanged
Farther Finance Advisors, LLC1,329$23.4K0.00%+753+130.7%Added
CWM, LLC979$17.0K0.00%+537+121.5%Added
BNP Paribas Arbitrage, SA884$15.6K0.00%+87+10.9%Added
Tower Research Capital LLC (TRC)804$14.2K0.00%+653+432.5%Added
GF Fund Management Co. Ltd.768$13.5K0.00%−261−25.4%Reduced
Horizon Investments, LLC735$13.0K0.00%−351−32.3%Reduced
SRS Capital Advisors, Inc.409$7.21K0.00%+409New
Smartleaf Asset Management LLC331$5.84K0.00%+149+81.9%Added
Caitong International Asset Management Co., Ltd325$5.73K0.00%+325New
Advisor Group Holdings, Inc.319$5.63K0.00%−13−3.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)317$5.59K0.00%−34,421−99.1%Reduced
The PNC Financial Services Group, Inc.302$5.33K0.00%−683−69.3%Reduced
Rhumbline Advisers281$4.96K0.00%−10−3.4%Reduced
Assetmark, Inc233$4.11K0.00%+226+3,228.6%Added
Quent Capital, LLC230$4.06K0.00%00.0%Unchanged
Parkside Financial Bank & Trust213$3.76K0.00%+213New
Private Trust Co NA206$3.63K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC203$3.58K0.00%+27+15.3%Added