| Nov 16, 2021 (view filing) | Nov 15 | 1 day | Pimstone Simon N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.6K | $31.33 | −$550.1K | −7.7%210.2K after | |
| Dec 7, 2021 (view filing) | Dec 6 | 1 day | Von Seggern ChristopherChief Commercial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +4.00K | $24.40 | +$97.6K | New position4.00K after | |
| Jan 21, 2022 (view filing) | Jan 21 | Same day | Kenney Christopher JohnChief Medical Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +700 | $28.81 | +$20.2K | New position700 after | |
| Mar 8, 2022 (view filing) | Mar 4-7 | 4 days | Empfield James R.EVP, Drug Discovery | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −51.2K | $30.63 | −$1.57M | −83.7%10.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 4 | 4 days | Robin SherringtonEVP, Strategy & Innovation | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.7K | $30.50 | −$662.2K | −55.7%17.2K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2022 (view filing) | Mar 4-8 | 4 days | Pimstone Simon N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −55.0K | $30.51 | −$1.68M | −22.2%193.1K after | From originalReported on the original filing 0001209191-22-017341. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.15 lotsThis row combines 15 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 16, 2022 (view filing) | Aug 12-16 | 4 days | Pimstone Simon N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −177.1K | $38.25 | −$6.78M | −96.7%6.00K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 16, 2022 (view filing) | Aug 12 | 4 days | Empfield James R.EVP, Drug Discovery | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −57.7K | $38.31 | −$2.21M | −85.2%10.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 2, 2022 (view filing) | Aug 31-Sep 1 | 2 days | Robin SherringtonEVP, Strategy & Innovation | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −65.2K | $38.31 | −$2.50M | −79.5%16.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 7, 2022 (view filing) | Sep 2 | 5 days | Aulin SherryChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.4K | $39.57 | −$607.6K | −100.0%0 after | |
| Nov 28, 2022 (view filing) | Nov 23-25 | 5 days | Patou GaryDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.99K | $34.55 | −$138.0K | −14.5%23.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 9, 2023 (view filing) | Mar 7 | 2 days | Pimstone Simon N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.2K | $36.98 | −$711.2K | −25.9%55.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 24, 2023 (view filing) | Mar 24 | Same day | Kenney Christopher JohnChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −700 | $35.01 | −$24.5K | −100.0%0 after | |
| May 26, 2023 (view filing) | May 24 | 2 days | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.7K | $41.41 | −$1.31M | −50.3%31.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 1, 2023 (view filing) | May 30-Jun 1 | 2 days | Pimstone Simon N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −131.2K | $38.90 | −$5.10M | −95.6%6.00K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 24, 2023 (view filing) | Aug 24 | Same day | Svoronos DawnDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $38.70 | −$967.5K | −50.0%25.0K after | |
| Dec 15, 2023 (view filing) | Dec 13 | 2 days | Patou GaryDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.4K | $39.29 | −$447.1K | −32.6%23.6K after | From originalReported on the original filing 0000950170-23-070841. A later amendment (Form 4/A) restated only part of that filing, so this trade still stands and is listed under the amendment. The filing date shown is the original's.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 15, 2023 (view filing) | Dec 14 | 1 day | Patou GaryDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.60K | $41.05 | −$311.9K | −60.8%4.90K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Mar 8, 2024 (view filing) | Mar 7 | 1 day | Gannon StevenDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.0K | $46.28 | −$601.6K | −86.7%2.00K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 8, 2024 (view filing) | Mar 7 | 1 day | Robin SherringtonEVP, Strategy & Innovation | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.14K | $46.28 | −$330.3K | −45.9%8.40K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 11, 2024 (view filing) | Mar 8 | 3 days | Garofalo Elizabeth A.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.09K | $45.69 | −$95.6K | −100.0%0 after | |
| Nov 22, 2024 (view filing) | Nov 22 | Same day | Patou GaryDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.89K | $41.08 | −$200.9K | −17.2%23.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 19, 2024 (view filing) | Dec 18 | 1 day | Aulin SherryChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.7K | $41.21 | −$770.9K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 27, 2025 (view filing) | Jan 23-27 | 4 days | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −55.0K | $40.25 | −$2.21M | −63.7%31.3K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 6, 2025 (view filing) | Jun 5 | 1 day | Gannon StevenDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3 | $30.48 | −$91.44 | 0.0%7.14K after | |
| Oct 1, 2025 (view filing) | Oct 1 | Same day | Mortimer IanPRESIDENT, CEO & INTERIM CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $40.16 | −$1.00M | −44.4%31.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 3, 2025 (view filing) | Nov 28 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −97 | $45.01 | −$4.37K | −0.3%31.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 9, 2025 (view filing) | Dec 5-8 | 4 days | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.2K | $45.33 | −$1.14M | −80.8%6.00K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 2, 2026 (view filing) | Jan 2 | Same day | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −40.0K | $44.43 | −$1.78M | −87.0%6.00K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 9-10 | 2 days | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −281.3K | $60.32 | −$17.0M | −95.0%14.7K after | 10 lotsThis row combines 10 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 10 | 1 day | DiFabio AndreaChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.61K | $60.11 | −$156.7K | −34.8%4.89K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 10 | 1 day | Kenney Christopher JohnChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.77K | $60.11 | −$166.6K | −36.9%4.73K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2026 (view filing) | Mar 13 | Same day | Mortimer IanPRESIDENT & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.31K | $55.23 | −$403.6K | −26.8%19.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2026 (view filing) | Mar 13 | Same day | DiFabio AndreaChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.34K | $55.23 | −$74.1K | −15.5%7.30K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 13, 2026 (view filing) | Mar 13 | Same day | Kenney Christopher JohnChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.41K | $55.23 | −$77.9K | −16.6%7.07K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 8, 2026 (view filing) | Jun 5 | 3 days | Cannon GillianDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.19K | $53.14 | −$63.2K | −45.0%1.46K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 8, 2026 (view filing) | Jun 5 | 3 days | Patou GaryDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.32K | $53.14 | −$70.3K | −5.0%24.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 13, 2026 (view filing)4:33 PM ET | Aug 11 | 2 days | Gannon StevenDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $64.06 | −$640.5K | −84.2%1.87K after | |
| Aug 31, 2026 (view filing)9:59 PM ET | Aug 28 | 3 days | Kenney Christopher JohnChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.07K | $60.25 | −$425.8K | −100.0%2 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
