Twist Bioscience Corp
TWST- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001581280
In the last 90 days, Twist Bioscience Corp insiders filed 0 open-market purchases and 30 sales; 337 institutions reported holding it in 13F filings for Q2 2026, worth $7.85B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Twist Bioscience Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 244
- +10 vs. Q3 2025
- Shares held
- 75.0M
- +1.35M (+1.8%) vs. Q3 2025
- Total value
- $2.38B
- +$306.8M (+14.8%) vs. Q3 2025
- New holders
- 48
- 75 more added
- Sold out
- 38
- 77 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TWST on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 337 | $7.85B |
| Q1 2026 | 281 | $3.66B |
| Q4 2025 | 244 | $2.38B |
| Q3 2025 | 239 | $2.08B |
| Q2 2025 | 244 | $2.62B |
| Q1 2025 | 263 | $2.73B |
| Q4 2024 | 247 | $3.08B |
| Q3 2024 | 246 | $2.99B |
| Q2 2024 | 263 | $3.25B |
| Q1 2024 | 238 | $2.30B |
| Q4 2023 | 219 | $2.46B |
| Q3 2023 | 196 | $1.34B |
| Q2 2023 | 194 | $1.39B |
| Q1 2023 | 203 | $956.8M |
| Q4 2022 | 199 | $1.45B |
| Q3 2022 | 221 | $2.04B |
| Q2 2022 | 205 | $2.01B |
| Q1 2022 | 213 | $2.92B |
| Q4 2021 | 237 | $3.96B |
| Q3 2021 | 238 | $5.20B |
| Q2 2021 | 245 | $6.40B |
| Q1 2021 | 240 | $5.82B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Twist Bioscience Corp; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Geneos Wealth Management Inc. | 8,950 | $283.9K | 0.01% | +3,500+64.2% | Added |
| Entropy Technologies, LP | 9,132 | $289.7K | 0.02% | +9,132 | New |
| Quest Partners LLC | 9,455 | $299.9K | 0.02% | −13,100−58.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 9,964 | $316.1K | 0.02% | −616−5.8% | Reduced |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 9,992 | $316.9K | 0.05% | +9,992 | New |
| Great West Life Assurance Co | 10,153 | $321.0K | 0.00% | −10,332−50.4% | Reduced |
| Creative Planning | 10,211 | $323.9K | 0.00% | +10,211 | New |
| Quantbot Technologies LP | 10,252 | $325.2K | 0.01% | +10,252 | New |
| Voya Investment Management LLC | 10,598 | $336.2K | 0.00% | 00.0% | Unchanged |
| Isthmus Partners, LLC | 11,145 | $353.5K | 0.04% | 00.0% | Unchanged |
| QRG Capital Management, Inc. | 12,049 | $382.2K | 0.00% | +325+2.8% | Added |
| Massar Capital Management, LP | 12,250 | $388.6K | 0.08% | +12,250 | New |
| KLP Kapitalforvaltning AS | 12,900 | $409.2K | 0.00% | +800+6.6% | Added |
| ProShare Advisors LLC | 13,636 | $432.5K | 0.00% | +1,375+11.2% | Added |
| Pekin Hardy Strauss, Inc. | 14,450 | $458.4K | 0.04% | +14,450 | New |
| CWM Advisors, LLC | 14,808 | $469.7K | 0.04% | −1,595−9.7% | Reduced |
| Rockefeller Capital Management L.P. | 14,970 | $474.8K | 0.00% | +3,359+28.9% | Added |
| Quadrature Capital Ltd | 14,998 | $475.7K | 0.00% | +14,998 | New |
| Cambridge Investment Research Advisors, Inc. | 15,236 | $483.0K | 0.00% | +15,236 | New |
| Police & Firemen's Retirement System of New Jersey | 15,308 | $485.6K | 0.00% | −1,057−6.5% | Reduced |
| Jump Financial, LLC | 16,707 | $529.9K | 0.01% | +16,707 | New |
| Arizona State Retirement System | 16,810 | $533.2K | 0.00% | −874−4.9% | Reduced |
| Virginia Retirement Systems Et Al | 17,538 | $556.3K | 0.00% | −2,150−10.9% | Reduced |
| Quantinno Capital Management LP | 17,675 | $560.7K | 0.00% | +17,675 | New |
| CIBC Private Wealth Group, LLC | 18,028 | $571.8K | 0.00% | +10.0% | Added |
| State Board of Administration of Florida Retirement System | 18,539 | $588.1K | 0.00% | 00.0% | Unchanged |
| Odyssean, LLC | 18,935 | $600.6K | 0.43% | +18,935 | New |
| Handelsbanken Fonder AB | 20,400 | $647.0K | 0.00% | +2,500+14.0% | Added |
| Steel Peak Wealth Management LLC | 20,868 | $661.9K | 0.02% | +2,570+14.0% | Added |
| Brandywine Managers, LLC | 20,970 | $665.2K | 0.33% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 21,057 | $667.9K | 0.00% | +2,893+15.9% | Added |
| Meridiem Capital Partners LP | 21,205 | $672.6K | 0.04% | +21,205 | New |
| US Bancorp | 21,366 | $677.7K | 0.00% | +20,594+2,667.6% | Added |
| Prelude Capital Management, LLC | 22,035 | $699.0K | 0.05% | +22,035 | New |
| Guggenheim Capital LLC | 22,428 | $711.4K | 0.01% | −1,312−5.5% | Reduced |
| Russell Investments Group, Ltd. | 22,444 | $711.9K | 0.00% | −41,454−64.9% | Reduced |
| Raymond James Financial Inc | 22,959 | $728.3K | 0.00% | −18,850−45.1% | Reduced |
| Knights of Columbus Asset Advisors LLC | 23,005 | $729.7K | 0.04% | −117−0.5% | Reduced |
| D.A. Davidson & Co. | 25,237 | $800.5K | 0.00% | +305+1.2% | Added |
| Intech Investment Management LLC | 25,477 | $808.1K | 0.01% | +643+2.6% | Added |
| Janus Henderson Group PLC | 25,580 | $810.6K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 25,865 | $820.4K | 0.00% | −2,268−8.1% | Reduced |
| Comprehensive Financial Management LLC | 26,273 | $833.4K | 0.03% | 00.0% | Unchanged |
| Exchange Traded Concepts, LLC | 26,323 | $835.0K | 0.01% | −2,778−9.5% | Reduced |
| D. E. Shaw & Co., Inc. | 27,581 | $874.9K | 0.00% | +27,581 | New |
| Benjamin Edwards Inc | 29,632 | $939.8K | 0.01% | +1,309+4.6% | Added |
| Two Sigma Advisers, LP | 31,400 | $996.0K | 0.00% | +5,400+20.8% | Added |
| Citadel Advisors LLC | 32,049 | $1.02M | 0.00% | −83,196−72.2% | Reduced |
| Royal Bank of Canada | 33,234 | $1.05M | 0.00% | −95,256−74.1% | Reduced |
| MetLife Investment Management | 33,236 | $1.05M | 0.01% | −1,491−4.3% | Reduced |
| Ameriprise Financial Inc | 33,348 | $1.06M | 0.00% | −62,933−65.4% | Reduced |
| State of Wisconsin Investment Board | 34,547 | $1.10M | 0.00% | −2,639−7.1% | Reduced |
| Maxi Investments CY Ltd | 35,000 | $1.11M | 0.20% | +35,000 | New |
| Squarepoint Ops LLC | 35,717 | $1.13M | 0.00% | −40,080−52.9% | Reduced |
| Victory Capital Management Inc | 37,555 | $1.19M | 0.00% | −9,690−20.5% | Reduced |
| Envestnet Asset Management Inc | 38,649 | $1.23M | 0.00% | −11,191−22.5% | Reduced |
| HighMark Wealth Management LLC | 39,462 | $1.25M | 0.51% | 00.0% | Unchanged |
| Algert Global LLC | 40,601 | $1.29M | 0.02% | −19,700−32.7% | Reduced |
| Profund Advisors LLC | 42,355 | $1.34M | 0.04% | +17,701+71.8% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 44,668 | $1.45M | 0.00% | +4,704+11.8% | Added |
| Clarius Group, LLC | 49,635 | $1.57M | 0.09% | 00.0% | Unchanged |
| Ieq Capital, LLC | 51,335 | $1.63M | 0.00% | +51+0.1% | Added |
| LPL Financial LLC | 53,043 | $1.68M | 0.00% | +17,644+49.8% | Added |
| Franklin Resources Inc | 53,881 | $1.71M | 0.00% | −204,818−79.2% | Reduced |
| Deutsche Bank AG | 55,671 | $1.77M | 0.00% | −44,844−44.6% | Reduced |
| Conestoga Capital Advisors, LLC | 56,785 | $1.80M | 0.03% | +1,185+2.1% | Added |
| California State Teachers Retirement System | 58,337 | $1.85M | 0.00% | −80.0% | Reduced |
| Price T Rowe Associates Inc | 58,985 | $1.87M | 0.00% | +5,135+9.5% | Added |
| Canada Pension Plan Investment Board | 60,200 | $1.91M | 0.00% | +11,300+23.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 65,122 | $2.08M | 0.00% | −468−0.7% | Reduced |
| Lazard Asset Management LLC | 66,027 | $2.09M | 0.00% | −12,323−15.7% | Reduced |
| Alliancebernstein L.P. | 66,524 | $2.11M | 0.00% | −76−0.1% | Reduced |
| FMR LLC | 68,937 | $2.19M | 0.00% | −150,595−68.6% | Reduced |
| Susquehanna International Group, LLP | 70,753 | $2.24M | 0.00% | +53,798+317.3% | Added |
| HRT Financial LP | 73,127 | $2.32M | 0.01% | +73,127 | New |
| Wells Fargo & Company | 74,819 | $2.37M | 0.00% | +28,059+60.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 76,318 | $2.42M | 0.00% | +855+1.1% | Added |
| SG Americas Securities, LLC | 76,484 | $2.43M | 0.00% | +59,500+350.3% | Added |
| Aquatic Capital Management LLC | 78,469 | $2.49M | 0.07% | +56,206+252.5% | Added |
| Nomura Asset Management International Inc. | 80,552 | $2.56M | 0.00% | +80,552 | New |
| Blair William & Co | 81,561 | $2.59M | 0.01% | +22,482+38.1% | Added |
| Rhumbline Advisers | 91,122 | $2.89M | 0.00% | −4,085−4.3% | Reduced |
| Fred Alger Management, LLC | 94,111 | $2.99M | 0.01% | −2,950−3.0% | Reduced |
| Jacobs Levy Equity Management, Inc | 103,117 | $3.27M | 0.01% | −394,021−79.3% | Reduced |
| Natixis | 103,688 | $3.29M | 0.01% | +103,688 | New |
| Rafferty Asset Management, LLC | 114,258 | $3.62M | 0.01% | −100.0% | Reduced |
| Swiss National Bank | 119,000 | $3.77M | 0.00% | +2,900+2.5% | Added |
| AQR Capital Management LLC | 129,552 | $4.11M | 0.00% | −78,356−37.7% | Reduced |
| Vestmark Advisory Solutions, Inc. | 129,990 | $4.12M | 0.06% | +12,741+10.9% | Added |
| Neuberger Berman Group LLC | 135,622 | $4.30M | 0.00% | −25,552−15.9% | Reduced |
| Oddo BHF Asset Management SAS | 135,650 | $4.30M | 0.16% | −36,137−21.0% | Reduced |
| Schonfeld Strategic Advisors LLC | 139,893 | $4.44M | 0.02% | +74,444+113.7% | Added |
| State of Michigan Retirement System | 153,172 | $4.86M | 0.02% | 00.0% | Unchanged |
| Legal & General Group Plc | 171,206 | $5.43M | 0.00% | +45,920+36.7% | Added |
| Qube Research & Technologies Ltd | 171,972 | $5.45M | 0.01% | −400,463−70.0% | Reduced |
| Bank of New York Mellon Corp | 182,941 | $5.80M | 0.00% | −315,320−63.3% | Reduced |
| Barclays PLC | 194,071 | $6.16M | 0.00% | −32,597−14.4% | Reduced |
| Trexquant Investment LP | 198,473 | $6.30M | 0.06% | −134,225−40.3% | Reduced |
| Ensign Peak Advisors, Inc | 212,593 | $6.74M | 0.01% | −13,679−6.0% | Reduced |
| JPMorgan Chase & Co | 215,147 | $6.82M | 0.00% | −803,087−78.9% | Reduced |