Skip to main content

Trevi Therapeutics, Inc.

TRVI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001563880

In the last 90 days, Trevi Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 218 institutions reported holding it in 13F filings for Q2 2026, worth $2.76B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Trevi Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
184
+20 vs. Q3 2025
Shares held
130.3M
+1.02M (+0.8%) vs. Q3 2025
Total value
$1.63B
+$448.6M (+37.9%) vs. Q3 2025
New holders
34
75 more added
Sold out
14
48 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TRVI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 184 institutions
Q1 2021: 19 institutionsQ2 2021: 17 institutionsQ3 2021: 18 institutionsQ4 2021: 17 institutionsQ1 2022: 23 institutionsQ2 2022: 32 institutionsQ3 2022: 40 institutionsQ4 2022: 37 institutionsQ1 2023: 36 institutionsQ2 2023: 53 institutionsQ3 2023: 55 institutionsQ4 2023: 63 institutionsQ1 2024: 80 institutionsQ2 2024: 77 institutionsQ3 2024: 93 institutionsQ4 2024: 110 institutionsQ1 2025: 137 institutionsQ2 2025: 154 institutionsQ3 2025: 164 institutionsQ4 2025: 184 institutionsQ1 2026: 198 institutionsQ2 2026: 218 institutions
Value heldQ4 2025: $1.63B
Q1 2021: $35.6MQ2 2021: $28.1MQ3 2021: $17.4MQ4 2021: $10.3MQ1 2022: $32.9MQ2 2022: $80.8MQ3 2022: $70.5MQ4 2022: $83.3MQ1 2023: $80.4MQ2 2023: $116.7MQ3 2023: $106.1MQ4 2023: $70.0MQ1 2024: $177.9MQ2 2024: $166.6MQ3 2024: $194.1MQ4 2024: $329.5MQ1 2025: $554.3MQ2 2025: $627.2MQ3 2025: $1.18BQ4 2025: $1.63BQ1 2026: $1.61BQ2 2026: $2.76B
Institutions holding TRVI and their total value by quarter
QuarterHoldersValue
Q2 2026218$2.76B
Q1 2026198$1.61B
Q4 2025184$1.63B
Q3 2025164$1.18B
Q2 2025154$627.2M
Q1 2025137$554.3M
Q4 2024110$329.5M
Q3 202493$194.1M
Q2 202477$166.6M
Q1 202480$177.9M
Q4 202363$70.0M
Q3 202355$106.1M
Q2 202353$116.7M
Q1 202336$80.4M
Q4 202237$83.3M
Q3 202240$70.5M
Q2 202232$80.8M
Q1 202223$32.9M
Q4 202117$10.3M
Q3 202118$17.4M
Q2 202117$28.1M
Q1 202119$35.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Trevi Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding TRVI in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
NEA Management Company, LLC13,222,228$165.5M8.44%00.0%Unchanged
Frazier Life Sciences Management, L.P.10,259,409$128.4M3.45%00.0%Unchanged
BlackRock, Inc.10,126,183$126.8M0.00%+225,130+2.3%Added
FMR LLC6,500,009$81.4M0.00%+3,200,118+97.0%Added
Vanguard Group Inc6,434,655$80.6M0.00%+607,669+10.4%Added
Vivo Capital, LLC5,094,668$63.8M4.12%00.0%Unchanged
Marshall Wace, LLP4,580,548$57.3M0.06%−261,203−5.4%Reduced
Rubric Capital Management LP3,766,749$47.2M0.56%−4,765,111−55.9%Reduced
Wellington Management Group LLP3,403,990$42.6M0.01%+150,102+4.6%Added
MPM Oncology Impact Management LP3,287,087$41.2M4.71%−119,868−3.5%Reduced
Viking Global Investors LPSuperinvestorViking Global Investors3,198,644$40.0M0.11%−1,930,231−37.6%Reduced
OrbiMed Advisors LLC3,190,700$39.9M0.82%−117,700−3.6%Reduced
Alliancebernstein L.P.3,082,986$38.6M0.01%−1,209,465−28.2%Reduced
Octagon Capital Advisors LP2,815,000$35.2M4.41%00.0%Unchanged
Eventide Asset Management, LLC2,622,306$32.8M0.51%+1,240,982+89.8%Added
State Street Corp2,435,000$30.5M0.00%+215,578+9.7%Added
Geode Capital Management, LLC2,412,885$30.2M0.00%+191,959+8.6%Added
Siren, L.L.C.2,286,867$28.6M0.85%−250,000−9.9%Reduced
Affinity Asset Advisors, LLC2,150,172$26.9M1.93%−649,828−23.2%Reduced
Acorn Capital Advisors, LLC2,144,844$26.9M9.10%00.0%Unchanged
Artia Global Partners LP2,013,602$25.2M4.05%+13,900+0.7%Added
Emerald Advisers, LLC1,892,276$23.7M0.73%+1,892,276New
Raymond James Financial Inc1,766,963$22.1M0.01%+355,926+25.2%Added
Logos Global Management LP1,550,000$19.4M1.29%−650,000−29.5%Reduced
Pictet Asset Management Holding SA1,532,013$19.2M0.02%+1,520,754+13,507.0%Added
Emerald Mutual Fund Advisers Trust1,272,373$15.9M0.78%+1,272,373New
Pivotal bioVenture Partners Investment Advisor LLC1,256,782$15.7M6.08%00.0%Unchanged
Frontier Capital Management Co LLC1,108,468$13.9M0.15%+1,108,468New
Bank of America Corp1,094,851$13.7M0.00%−741,988−40.4%Reduced
Goldman Sachs Group Inc1,056,891$13.2M0.00%+269,437+34.2%Added
Flputnam Investment Management Co1,053,427$13.2M0.19%+5,325+0.5%Added
Morgan Stanley1,050,296$13.1M0.00%−3,251,430−75.6%Reduced
Woodline Partners LP1,000,282$12.5M0.05%+900,000+897.5%Added
Point72 Asset Management, L.P.1,000,000$12.5M0.02%+58,071+6.2%Added
Nan Fung Trinity (HK) Ltd917,450$11.5M0.91%+827,875+924.2%Added
Soleus Capital Management, L.P.900,000$11.3M0.48%+875,000+3,500.0%Added
Charles Schwab Investment Management Inc836,800$10.5M0.00%+30,469+3.8%Added
Susquehanna International Group, LLP825,548$10.3M0.01%−775,194−48.4%Reduced
Northern Trust Corp761,966$9.54M0.00%+25,036+3.4%Added
Panagora Asset Management Inc693,001$8.68M0.03%+122,533+21.5%Added
Sphera Funds Management Ltd.598,534$7.49M1.57%−45,423−7.1%Reduced
Barclays PLC582,653$7.29M0.00%+365,768+168.6%Added
Millennium Management LLC570,226$7.14M0.01%−157,370−21.6%Reduced
Prudential Financial Inc549,219$6.88M0.01%−53,435−8.9%Reduced
EAM Investors, LLC541,242$6.78M0.75%−8,237−1.5%Reduced
Silverarc Capital Management, LLC541,240$6.78M0.98%−47,549−8.1%Reduced
Burkehill Global Management, LP525,000$6.57M0.43%00.0%Unchanged
Peregrine Capital Management LLC507,685$6.36M0.19%−112,779−18.2%Reduced
Invesco Ltd.498,926$6.25M0.00%+15,856+3.3%Added
J. Goldman & Co LP444,357$5.56M0.22%−348,449−44.0%Reduced
KVP Capital Advisors, LP414,000$5.18M5.35%+414,000New
StemPoint Capital LP399,557$5.00M0.86%+48,847+13.9%Added
Opaleye Management Inc.345,100$4.32M0.57%−44,900−11.5%Reduced
Ameriprise Financial Inc324,172$4.06M0.00%+324,172New
UBS Group AG274,628$3.44M0.00%−23,984−8.0%Reduced
Bank of New York Mellon Corp260,587$3.26M0.00%+34,248+15.1%Added
F/M Investments LLC241,483$3.02M0.11%+241,483New
Voya Investment Management LLC226,215$2.83M0.00%+211,035+1,390.2%Added
Velan Capital Investment Management LP205,000$2.57M1.49%00.0%Unchanged
Nuveen, LLC183,329$2.30M0.00%00.0%Unchanged
Balyasny Asset Management LLC174,641$2.19M0.00%−451,821−72.1%Reduced
Swiss National Bank168,200$2.11M0.00%+6,500+4.0%Added
Fred Alger Management, LLC157,980$1.98M0.01%−33,065−17.3%Reduced
Citadel Advisors LLC152,855$1.91M0.00%+50,321+49.1%Added
Superstring Capital Management LP148,292$1.86M0.99%+148,292New
SEI Investments Co147,941$1.85M0.00%+62,143+72.4%Added
D. E. Shaw & Co., Inc.141,312$1.77M0.00%+141,312New
UBS Asset Management Americas Inc140,733$1.76M0.00%+24,256+20.8%Added
BIT Capital GmbH130,000$1.63M0.07%+123,261+1,829.1%Added
HRT Financial LP125,104$1.57M0.00%+125,104New
SG Americas Securities, LLC124,562$1.56M0.00%+60,017+93.0%Added
Citigroup Inc123,498$1.55M0.00%+96,585+358.9%Added
State of Wisconsin Investment Board120,566$1.51M0.00%−2,710−2.2%Reduced
HighVista Strategies LLC106,159$1.33M0.34%+106,159New
Rhumbline Advisers105,922$1.33M0.00%−9,100−7.9%Reduced
Wells Fargo & Company101,279$1.27M0.00%+45,593+81.9%Added
Oppenheimer & Co Inc100,698$1.26M0.02%+2,030+2.1%Added
LMR Partners LLP100,000$1.25M0.01%00.0%Unchanged
Rosalind Advisors, Inc.100,000$1.25M0.48%00.0%Unchanged
Diadema Partners LP97,184$1.22M0.72%+11,354+13.2%Added
Erste Asset Management GmbH90,000$1.15M0.01%+90,000New
Sectoral Asset Management Inc84,255$1.05M0.85%−21,695−20.5%Reduced
XTX Topco Ltd83,818$1.05M0.03%+83,818New
California State Teachers Retirement System83,788$1.05M0.00%+2,091+2.6%Added
Two Sigma Investments, LP83,755$1.05M0.00%−36,175−30.2%Reduced
Comerica Bank83,027$1.04M0.00%+82,603+19,481.8%Added
Wexford Capital LP82,034$1.03M0.26%+82,034New
Legal & General Group Plc81,673$1.02M0.00%−299−0.4%Reduced
PFS Partners, LLC79,000$989.1K0.45%00.0%Unchanged
MAI Capital Management77,769$973.7K0.01%−20,723−21.0%Reduced
Hudson Bay Capital Management LP75,000$939.0K0.01%+75,000New
Campbell & CO Investment Adviser LLC71,097$890.1K0.04%+46,212+185.7%Added
Deutsche Bank AG70,833$886.8K0.00%+19,193+37.2%Added
Tudor Investment Corp Et Al68,481$857.4K0.00%+68,481New
WealthTrust Axiom LLC61,500$770.0K0.20%00.0%Unchanged
Optimize Financial Inc61,483$769.8K0.39%+884+1.5%Added
JPMorgan Chase & Co59,475$744.6K0.00%+660+1.1%Added
Russell Investments Group, Ltd.59,444$744.2K0.00%+2,984+5.3%Added
Kennedy Capital Management, Inc.56,269$704.5K0.01%+1,336+2.4%Added
LPL Financial LLC52,960$663.1K0.00%+12,510+30.9%Added