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Trevi Therapeutics, Inc.

TRVI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001563880

In the last 90 days, Trevi Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 218 institutions reported holding it in 13F filings for Q2 2026, worth $2.76B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Trevi Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
184
+20 vs. Q3 2025
Shares held
130.3M
+1.02M (+0.8%) vs. Q3 2025
Total value
$1.63B
+$448.6M (+37.9%) vs. Q3 2025
New holders
34
75 more added
Sold out
14
48 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TRVI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 184 institutions
Q1 2021: 19 institutionsQ2 2021: 17 institutionsQ3 2021: 18 institutionsQ4 2021: 17 institutionsQ1 2022: 23 institutionsQ2 2022: 32 institutionsQ3 2022: 40 institutionsQ4 2022: 37 institutionsQ1 2023: 36 institutionsQ2 2023: 53 institutionsQ3 2023: 55 institutionsQ4 2023: 63 institutionsQ1 2024: 80 institutionsQ2 2024: 77 institutionsQ3 2024: 93 institutionsQ4 2024: 110 institutionsQ1 2025: 137 institutionsQ2 2025: 154 institutionsQ3 2025: 164 institutionsQ4 2025: 184 institutionsQ1 2026: 198 institutionsQ2 2026: 218 institutions
Value heldQ4 2025: $1.63B
Q1 2021: $35.6MQ2 2021: $28.1MQ3 2021: $17.4MQ4 2021: $10.3MQ1 2022: $32.9MQ2 2022: $80.8MQ3 2022: $70.5MQ4 2022: $83.3MQ1 2023: $80.4MQ2 2023: $116.7MQ3 2023: $106.1MQ4 2023: $70.0MQ1 2024: $177.9MQ2 2024: $166.6MQ3 2024: $194.1MQ4 2024: $329.5MQ1 2025: $554.3MQ2 2025: $627.2MQ3 2025: $1.18BQ4 2025: $1.63BQ1 2026: $1.61BQ2 2026: $2.76B
Institutions holding TRVI and their total value by quarter
QuarterHoldersValue
Q2 2026218$2.76B
Q1 2026198$1.61B
Q4 2025184$1.63B
Q3 2025164$1.18B
Q2 2025154$627.2M
Q1 2025137$554.3M
Q4 2024110$329.5M
Q3 202493$194.1M
Q2 202477$166.6M
Q1 202480$177.9M
Q4 202363$70.0M
Q3 202355$106.1M
Q2 202353$116.7M
Q1 202336$80.4M
Q4 202237$83.3M
Q3 202240$70.5M
Q2 202232$80.8M
Q1 202223$32.9M
Q4 202117$10.3M
Q3 202118$17.4M
Q2 202117$28.1M
Q1 202119$35.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Trevi Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding TRVI in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Smartleaf Asset Management LLC1$130.00%00.0%Unchanged
US Bancorp4$500.00%00.0%Unchanged
Larson Financial Group LLC9$1130.00%+6+200.0%Added
Essential Partners LLC11$1380.00%00.0%Unchanged
SageView Advisory Group, LLC49$6140.00%+49New
Los Angeles Capital Management LLC87$9720.00%+87New
Cornerstone Financial Management LLC78$9770.00%+78New
Parkside Financial Bank & Trust140$1.75K0.00%00.0%Unchanged
GAMMA Investing LLC180$2.25K0.00%+111+160.9%Added
SRS Capital Advisors, Inc.206$2.58K0.00%+21+11.4%Added
Optiver Holding B.V.378$4.73K0.00%−510−57.4%Reduced
Daiwa Securities Group Inc.427$5.00K0.00%+122+40.0%Added
CWM, LLC381$5.00K0.00%+17+4.7%Added
Massmutual Trust Co FSB516$6.46K0.00%00.0%Unchanged
Sterling Capital Management LLC581$7.27K0.00%+369+174.1%Added
Aster Capital Management (DIFC) Ltd602$7.54K0.00%+602New
Jones Financial Companies LLLP620$7.76K0.00%−474−43.3%Reduced
Allworth Financial LP753$9.43K0.00%+700+1,320.8%Added
Quadrant Capital Group LLC789$9.88K0.00%00.0%Unchanged
Signaturefd, LLC835$10.5K0.00%+161+23.9%Added
Nisa Investment Advisors, LLC899$11.3K0.00%+730+432.0%Added
The PNC Financial Services Group, Inc.999$12.5K0.00%+414+70.8%Added
Bessemer Group Inc1,560$20.0K0.00%+1,560New
Aquatic Capital Management LLC1,978$24.8K0.00%+1,978New
Chung Wu Investment Group, LLC2,000$25.0K0.02%+400+25.0%Added
GF Fund Management Co. Ltd.2,519$31.5K0.00%−101−3.9%Reduced
Amalgamated Bank2,852$36.0K0.00%+284+11.1%Added
National Bank of Canada2,967$37.1K0.00%+31+1.1%Added
Hilton Head Capital Partners, LLC3,206$40.1K0.02%+3,206New
Caitong International Asset Management Co., Ltd4,022$50.4K0.01%+4,022New
Mirae Asset Global Investments Co., Ltd.6,231$78.0K0.00%+1,523+32.3%Added
Seven Fleet Capital Management LP7,110$89.0K0.06%+7,110New
Bellevue Group AG7,603$95.2K0.00%+7,603New
Ameritas Investment Partners, Inc.7,632$95.6K0.00%00.0%Unchanged
Quest Partners LLC7,988$100.0K0.01%−709−8.2%Reduced
Farther Finance Advisors, LLC9,270$116.1K0.00%+432+4.9%Added
DLD Asset Management, LP10,000$125.2K0.01%−45,000−81.8%Reduced
Abel Hall, LLC10,191$127.6K0.03%+10,191New
Tower Research Capital LLC (TRC)10,461$131.0K0.00%+7,675+275.5%Added
Kingsview Wealth Management, LLC10,638$133.2K0.00%+10,638New
Vontobel Holding Ltd.10,764$134.8K0.00%−11,095−50.8%Reduced
Teacher Retirement System of Texas12,603$157.8K0.00%−7,616−37.7%Reduced
Rafferty Asset Management, LLC16,499$206.6K0.00%+2,933+21.6%Added
NBC Securities, Inc.17,000$212.8K0.02%+15,000+750.0%Added
KLP Kapitalforvaltning AS18,300$229.1K0.00%+900+5.2%Added
Profund Advisors LLC19,378$242.6K0.01%−725−3.6%Reduced
Dymon Asia Capital (Singapore) Pte. Ltd.20,000$250.4K0.06%+20,000New
Chapin Davis, Inc.20,100$251.7K0.06%−15,000−42.7%Reduced
China Universal Asset Management Co., Ltd.20,895$261.6K0.02%−451−2.1%Reduced
Diversified Trust Co20,984$262.7K0.00%+2,675+14.6%Added
BNP Paribas Arbitrage, SA22,056$276.1K0.00%+3,844+21.1%Added
Axq Capital, LP22,204$278.0K0.06%+6,680+43.0%Added
ProShare Advisors LLC22,269$278.8K0.00%+2,947+15.3%Added
Qube Research & Technologies Ltd22,622$283.2K0.00%−629,057−96.5%Reduced
AlphaCentric Advisors LLC22,667$283.8K0.28%+22,667New
STRS Ohio23,700$296.7K0.00%−8,600−26.6%Reduced
Police & Firemen's Retirement System of New Jersey23,777$297.7K0.00%00.0%Unchanged
Arizona State Retirement System24,063$301.3K0.00%−599−2.4%Reduced
Harbour Capital Advisors, LLC27,500$327.0K0.07%00.0%Unchanged
New York State Common Retirement Fund27,765$347.6K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The27,937$349.8K0.00%−1,678−5.7%Reduced
Stifel Financial Corp28,288$354.2K0.00%+5,387+23.5%Added
Intech Investment Management LLC29,070$364.0K0.00%+3,741+14.8%Added
AQR Capital Management LLC29,202$365.6K0.00%−13,608−31.8%Reduced
United Bank31,200$390.6K0.05%00.0%Unchanged
Fox Run Management, L.L.C.31,346$392.5K0.06%+31,346New
Verition Fund Management LLC32,119$402.1K0.00%+32,119New
Royal Bank of Canada33,119$415.0K0.00%−135,875−80.4%Reduced
Trust Co of Toledo NA36,502$457.0K0.05%00.0%Unchanged
Dimensional Fund Advisors LP36,510$457.1K0.00%−4,933−11.9%Reduced
Janus Henderson Group PLC37,127$464.5K0.00%00.0%Unchanged
IMC-Chicago, LLC38,827$486.1K0.01%+8,225+26.9%Added
Z3 Capital Partners, LLC39,450$493.9K0.12%+39,450New
Creative Planning40,222$503.6K0.00%+14,047+53.7%Added
Mirae Asset Global ETFs Holdings Ltd.42,063$526.6K0.00%+1,438+3.5%Added
Steward Partners Investment Advisory, LLC44,095$552.1K0.00%+12,500+39.6%Added
Persistent Asset Partners Ltd45,830$573.8K0.28%+26,142+132.8%Added
Jane Street Group, LLC45,995$575.9K0.00%+45,995New
Zurcher Kantonalbank (Zurich Cantonalbank)46,681$584.4K0.00%+21,503+85.4%Added
Simplex Trading, LLC47,134$590.1K0.02%−16,015−25.4%Reduced
Franklin Resources Inc49,878$624.5K0.00%00.0%Unchanged
MetLife Investment Management50,250$629.1K0.00%−502−1.0%Reduced
Price T Rowe Associates Inc50,273$630.0K0.00%+3,414+7.3%Added
Allianz Asset Management GmbH52,800$661.1K0.00%+52,800New
LPL Financial LLC52,960$663.1K0.00%+12,510+30.9%Added
Kennedy Capital Management, Inc.56,269$704.5K0.01%+1,336+2.4%Added
Russell Investments Group, Ltd.59,444$744.2K0.00%+2,984+5.3%Added
JPMorgan Chase & Co59,475$744.6K0.00%+660+1.1%Added
Optimize Financial Inc61,483$769.8K0.39%+884+1.5%Added
WealthTrust Axiom LLC61,500$770.0K0.20%00.0%Unchanged
Tudor Investment Corp Et Al68,481$857.4K0.00%+68,481New
Deutsche Bank AG70,833$886.8K0.00%+19,193+37.2%Added
Campbell & CO Investment Adviser LLC71,097$890.1K0.04%+46,212+185.7%Added
Hudson Bay Capital Management LP75,000$939.0K0.01%+75,000New
MAI Capital Management77,769$973.7K0.01%−20,723−21.0%Reduced
PFS Partners, LLC79,000$989.1K0.45%00.0%Unchanged
Legal & General Group Plc81,673$1.02M0.00%−299−0.4%Reduced
Wexford Capital LP82,034$1.03M0.26%+82,034New
Comerica Bank83,027$1.04M0.00%+82,603+19,481.8%Added
Two Sigma Investments, LP83,755$1.05M0.00%−36,175−30.2%Reduced