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Shattuck Labs, Inc.

STTK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680367

In the last 90 days, Shattuck Labs, Inc. insiders filed 0 open-market purchases and 3 sales; 100 institutions reported holding it in 13F filings for Q2 2026, worth $581.3M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Shattuck Labs, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
+13 vs. Q3 2025
Shares held
42.0M
+6.18M (+17.2%) vs. Q3 2025
Total value
$153.4M
+$67.7M (+79.0%) vs. Q3 2025
New holders
17
18 more added
Sold out
4
13 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 65 institutions
Q1 2021: 56 institutionsQ2 2021: 68 institutionsQ3 2021: 70 institutionsQ4 2021: 82 institutionsQ1 2022: 77 institutionsQ2 2022: 72 institutionsQ3 2022: 63 institutionsQ4 2022: 48 institutionsQ1 2023: 49 institutionsQ2 2023: 42 institutionsQ3 2023: 41 institutionsQ4 2023: 57 institutionsQ1 2024: 70 institutionsQ2 2024: 74 institutionsQ3 2024: 78 institutionsQ4 2024: 75 institutionsQ1 2025: 75 institutionsQ2 2025: 61 institutionsQ3 2025: 56 institutionsQ4 2025: 65 institutionsQ1 2026: 84 institutionsQ2 2026: 100 institutions
Value heldQ4 2025: $153.4M
Q1 2021: $682.7MQ2 2021: $750.7MQ3 2021: $525.3MQ4 2021: $204.6MQ1 2022: $102.1MQ2 2022: $87.0MQ3 2022: $55.7MQ4 2022: $46.9MQ1 2023: $59.7MQ2 2023: $62.9MQ3 2023: $30.2MQ4 2023: $207.8MQ1 2024: $281.3MQ2 2024: $131.9MQ3 2024: $124.8MQ4 2024: $38.3MQ1 2025: $29.6MQ2 2025: $22.7MQ3 2025: $87.0MQ4 2025: $153.4MQ1 2026: $360.4MQ2 2026: $581.3M
Institutions holding STTK and their total value by quarter
QuarterHoldersValue
Q2 2026100$581.3M
Q1 202684$360.4M
Q4 202565$153.4M
Q3 202556$87.0M
Q2 202561$22.7M
Q1 202575$29.6M
Q4 202475$38.3M
Q3 202478$124.8M
Q2 202474$131.9M
Q1 202470$281.3M
Q4 202357$207.8M
Q3 202341$30.2M
Q2 202342$62.9M
Q1 202349$59.7M
Q4 202248$46.9M
Q3 202263$55.7M
Q2 202272$87.0M
Q1 202277$102.1M
Q4 202182$204.6M
Q3 202170$525.3M
Q2 202168$750.7M
Q1 202156$682.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Shattuck Labs, Inc.; share changes are against Q3 2025.

Institutions holding STTK in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC6,306,127$23.0M0.47%00.0%Unchanged
Adage Capital Partners GP, L.L.C.6,306,127$23.0M0.03%00.0%Unchanged
Redmile Group, LLC5,539,724$20.2M1.49%00.0%Unchanged
NEXTBio Capital Management LP3,149,907$11.5M6.74%+3,149,907New
Prosight Management, LP2,381,502$8.69M1.80%−3,069,693−56.3%Reduced
Vanguard Group Inc2,377,746$8.68M0.00%+249,345+11.7%Added
Price T Rowe Associates Inc1,926,140$7.03M0.00%+1,926,140New
Clark Estates Inc1,475,648$5.39M1.31%00.0%Unchanged
683 Capital Management, LLC1,390,000$5.07M0.42%−142,216−9.3%Reduced
T. Rowe Price Investment Management, Inc.1,354,761$4.95M0.00%+1,354,761New
Pinnacle Associates Ltd1,350,638$4.93M0.06%−38,085−2.7%Reduced
Bank of America Corp1,106,617$4.04M0.00%−25,271−2.2%Reduced
Point72 Asset Management, L.P.1,068,231$3.90M0.01%+1,068,231New
Geode Capital Management, LLC618,277$2.26M0.00%+150,318+32.1%Added
Standard Life Aberdeen plc531,177$1.94M0.00%+436,673+462.1%Added
Marshall Wace, LLP489,912$1.79M0.00%−166,741−25.4%Reduced
Millennium Management LLC477,408$1.74M0.00%−213,493−30.9%Reduced
Two Sigma Investments, LP437,729$1.60M0.00%+29,131+7.1%Added
BlackRock, Inc.418,529$1.53M0.00%+7,237+1.8%Added
FMR LLC392,600$1.43M0.00%+389,233+11,560.2%Added
Renaissance Technologies LLC340,700$1.24M0.00%+123,833+57.1%Added
TD Asset Management Inc251,050$916.3K0.00%+251,050New
State Street Corp215,418$786.3K0.00%+38,700+21.9%Added
Sphera Funds Management Ltd.195,212$712.5K0.15%+195,212New
Two Sigma Advisers, LP170,600$622.7K0.00%+57,923+51.4%Added
Pathstone Holdings, LLC157,083$573.4K0.00%00.0%Unchanged
Susquehanna International Group, LLP148,427$541.8K0.00%+80,311+117.9%Added
Northern Trust Corp145,445$530.9K0.00%+54,173+59.4%Added
Manufacturers Life Insurance Company, The135,056$486.2K0.00%+135,056New
Goldman Sachs Group Inc128,165$467.8K0.00%+111,365+662.9%Added
Bank of New York Mellon Corp110,394$402.9K0.00%00.0%Unchanged
LBJ Family Wealth Advisors, Ltd.82,177$300.0K0.16%00.0%Unchanged
Acadian Asset Management LLC79,367$289.0K0.00%−249,921−75.9%Reduced
Citadel Advisors LLC68,846$251.3K0.00%+68,846New
Connor, Clark & Lunn Investment Management Ltd.65,734$239.9K0.00%+65,734New
Squarepoint Ops LLC64,785$236.5K0.00%+45,525+236.4%Added
Jane Street Group, LLC54,046$197.3K0.00%−45,001−45.4%Reduced
Bridgeway Capital Management, LLC42,300$154.4K0.00%00.0%Unchanged
EP Wealth Advisors, LLC41,167$150.3K0.00%+41,167New
Piper Sandler & Co.39,467$144.1K0.10%00.0%Unchanged
Qube Research & Technologies Ltd38,757$141.5K0.00%+22,806+143.0%Added
Invesco Ltd.28,231$103.0K0.00%+28,231New
Omers Administration Corp26,500$96.7K0.00%+26,500New
Ritholtz Wealth Management26,000$94.9K0.00%00.0%Unchanged
XTX Topco Ltd24,873$90.8K0.00%−1,353−5.2%Reduced
Citigroup Inc24,832$90.6K0.00%+9,724+64.4%Added
Dimensional Fund Advisors LP23,192$84.7K0.00%+23,192New
Mallini Complete Financial Planning LLC22,632$82.6K0.07%+22,632New
RSM US Wealth Management LLC27,251$76.5K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc20,881$76.2K0.00%00.0%Unchanged
Morgan Stanley18,108$66.1K0.00%+1,457+8.8%Added
Prudential Financial Inc17,700$64.6K0.00%00.0%Unchanged
American Century Companies Inc17,282$63.1K0.00%+17,282New
Keel Point, LLC14,270$52.1K0.00%−31,903−69.1%Reduced
Engineers Gate Manager LP13,670$49.9K0.00%00.0%Unchanged
UBS Group AG13,204$48.2K0.00%+11,771+821.4%Added
Creative Planning12,335$45.0K0.00%00.0%Unchanged
Ameriprise Financial Inc11,500$42.0K0.00%+11,500New
Stoneridge Investment Partners LLC10,453$38.0K0.03%+10,453New
BNP Paribas Arbitrage, SA540$1.97K0.00%−418−43.6%Reduced
JPMorgan Chase & Co343$1.25K0.00%+40+13.2%Added
SBI Securities Co., Ltd.92$3360.00%00.0%Unchanged
Optiver Holding B.V.66$2410.00%00.0%Unchanged
Royal Bank of Canada64$00.00%−14,457−99.6%Reduced
CWM, LLC43$00.00%−84−66.1%Reduced
Virtu Financial LLC0$00.00%−16,054−100.0%Sold out
Turtle Creek Wealth Advisors, LLC0$00.00%−12,235−100.0%Sold out
AssuredPartners Investment Advisors, LLC0$00.00%−10,000−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−14−100.0%Sold out
Takeda Pharmaceutical Co Ltd––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed