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Shattuck Labs, Inc.

STTK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680367

In the last 90 days, Shattuck Labs, Inc. insiders filed 0 open-market purchases and 3 sales; 100 institutions reported holding it in 13F filings for Q2 2026, worth $581.3M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Shattuck Labs, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
+13 vs. Q3 2025
Shares held
42.0M
+6.18M (+17.2%) vs. Q3 2025
Total value
$153.4M
+$67.7M (+79.0%) vs. Q3 2025
New holders
17
18 more added
Sold out
4
13 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 65 institutions
Q1 2021: 56 institutionsQ2 2021: 68 institutionsQ3 2021: 70 institutionsQ4 2021: 82 institutionsQ1 2022: 77 institutionsQ2 2022: 72 institutionsQ3 2022: 63 institutionsQ4 2022: 48 institutionsQ1 2023: 49 institutionsQ2 2023: 42 institutionsQ3 2023: 41 institutionsQ4 2023: 57 institutionsQ1 2024: 70 institutionsQ2 2024: 74 institutionsQ3 2024: 78 institutionsQ4 2024: 75 institutionsQ1 2025: 75 institutionsQ2 2025: 61 institutionsQ3 2025: 56 institutionsQ4 2025: 65 institutionsQ1 2026: 84 institutionsQ2 2026: 100 institutions
Value heldQ4 2025: $153.4M
Q1 2021: $682.7MQ2 2021: $750.7MQ3 2021: $525.3MQ4 2021: $204.6MQ1 2022: $102.1MQ2 2022: $87.0MQ3 2022: $55.7MQ4 2022: $46.9MQ1 2023: $59.7MQ2 2023: $62.9MQ3 2023: $30.2MQ4 2023: $207.8MQ1 2024: $281.3MQ2 2024: $131.9MQ3 2024: $124.8MQ4 2024: $38.3MQ1 2025: $29.6MQ2 2025: $22.7MQ3 2025: $87.0MQ4 2025: $153.4MQ1 2026: $360.4MQ2 2026: $581.3M
Institutions holding STTK and their total value by quarter
QuarterHoldersValue
Q2 2026100$581.3M
Q1 202684$360.4M
Q4 202565$153.4M
Q3 202556$87.0M
Q2 202561$22.7M
Q1 202575$29.6M
Q4 202475$38.3M
Q3 202478$124.8M
Q2 202474$131.9M
Q1 202470$281.3M
Q4 202357$207.8M
Q3 202341$30.2M
Q2 202342$62.9M
Q1 202349$59.7M
Q4 202248$46.9M
Q3 202263$55.7M
Q2 202272$87.0M
Q1 202277$102.1M
Q4 202182$204.6M
Q3 202170$525.3M
Q2 202168$750.7M
Q1 202156$682.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Shattuck Labs, Inc.; share changes are against Q3 2025.

Institutions holding STTK in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada64$00.00%−14,457−99.6%Reduced
CWM, LLC43$00.00%−84−66.1%Reduced
Optiver Holding B.V.66$2410.00%00.0%Unchanged
SBI Securities Co., Ltd.92$3360.00%00.0%Unchanged
JPMorgan Chase & Co343$1.25K0.00%+40+13.2%Added
BNP Paribas Arbitrage, SA540$1.97K0.00%−418−43.6%Reduced
Stoneridge Investment Partners LLC10,453$38.0K0.03%+10,453New
Ameriprise Financial Inc11,500$42.0K0.00%+11,500New
Creative Planning12,335$45.0K0.00%00.0%Unchanged
UBS Group AG13,204$48.2K0.00%+11,771+821.4%Added
Engineers Gate Manager LP13,670$49.9K0.00%00.0%Unchanged
Keel Point, LLC14,270$52.1K0.00%−31,903−69.1%Reduced
American Century Companies Inc17,282$63.1K0.00%+17,282New
Prudential Financial Inc17,700$64.6K0.00%00.0%Unchanged
Morgan Stanley18,108$66.1K0.00%+1,457+8.8%Added
Charles Schwab Investment Management Inc20,881$76.2K0.00%00.0%Unchanged
RSM US Wealth Management LLC27,251$76.5K0.00%00.0%Unchanged
Mallini Complete Financial Planning LLC22,632$82.6K0.07%+22,632New
Dimensional Fund Advisors LP23,192$84.7K0.00%+23,192New
Citigroup Inc24,832$90.6K0.00%+9,724+64.4%Added
XTX Topco Ltd24,873$90.8K0.00%−1,353−5.2%Reduced
Ritholtz Wealth Management26,000$94.9K0.00%00.0%Unchanged
Omers Administration Corp26,500$96.7K0.00%+26,500New
Invesco Ltd.28,231$103.0K0.00%+28,231New
Qube Research & Technologies Ltd38,757$141.5K0.00%+22,806+143.0%Added
Piper Sandler & Co.39,467$144.1K0.10%00.0%Unchanged
EP Wealth Advisors, LLC41,167$150.3K0.00%+41,167New
Bridgeway Capital Management, LLC42,300$154.4K0.00%00.0%Unchanged
Jane Street Group, LLC54,046$197.3K0.00%−45,001−45.4%Reduced
Squarepoint Ops LLC64,785$236.5K0.00%+45,525+236.4%Added
Connor, Clark & Lunn Investment Management Ltd.65,734$239.9K0.00%+65,734New
Citadel Advisors LLC68,846$251.3K0.00%+68,846New
Acadian Asset Management LLC79,367$289.0K0.00%−249,921−75.9%Reduced
LBJ Family Wealth Advisors, Ltd.82,177$300.0K0.16%00.0%Unchanged
Bank of New York Mellon Corp110,394$402.9K0.00%00.0%Unchanged
Goldman Sachs Group Inc128,165$467.8K0.00%+111,365+662.9%Added
Manufacturers Life Insurance Company, The135,056$486.2K0.00%+135,056New
Northern Trust Corp145,445$530.9K0.00%+54,173+59.4%Added
Susquehanna International Group, LLP148,427$541.8K0.00%+80,311+117.9%Added
Pathstone Holdings, LLC157,083$573.4K0.00%00.0%Unchanged
Two Sigma Advisers, LP170,600$622.7K0.00%+57,923+51.4%Added
Sphera Funds Management Ltd.195,212$712.5K0.15%+195,212New
State Street Corp215,418$786.3K0.00%+38,700+21.9%Added
TD Asset Management Inc251,050$916.3K0.00%+251,050New
Renaissance Technologies LLC340,700$1.24M0.00%+123,833+57.1%Added
FMR LLC392,600$1.43M0.00%+389,233+11,560.2%Added
BlackRock, Inc.418,529$1.53M0.00%+7,237+1.8%Added
Two Sigma Investments, LP437,729$1.60M0.00%+29,131+7.1%Added
Millennium Management LLC477,408$1.74M0.00%−213,493−30.9%Reduced
Marshall Wace, LLP489,912$1.79M0.00%−166,741−25.4%Reduced
Standard Life Aberdeen plc531,177$1.94M0.00%+436,673+462.1%Added
Geode Capital Management, LLC618,277$2.26M0.00%+150,318+32.1%Added
Point72 Asset Management, L.P.1,068,231$3.90M0.01%+1,068,231New
Bank of America Corp1,106,617$4.04M0.00%−25,271−2.2%Reduced
Pinnacle Associates Ltd1,350,638$4.93M0.06%−38,085−2.7%Reduced
T. Rowe Price Investment Management, Inc.1,354,761$4.95M0.00%+1,354,761New
683 Capital Management, LLC1,390,000$5.07M0.42%−142,216−9.3%Reduced
Clark Estates Inc1,475,648$5.39M1.31%00.0%Unchanged
Price T Rowe Associates Inc1,926,140$7.03M0.00%+1,926,140New
Vanguard Group Inc2,377,746$8.68M0.00%+249,345+11.7%Added
Prosight Management, LP2,381,502$8.69M1.80%−3,069,693−56.3%Reduced
NEXTBio Capital Management LP3,149,907$11.5M6.74%+3,149,907New
Redmile Group, LLC5,539,724$20.2M1.49%00.0%Unchanged
OrbiMed Advisors LLC6,306,127$23.0M0.47%00.0%Unchanged
Adage Capital Partners GP, L.L.C.6,306,127$23.0M0.03%00.0%Unchanged
Virtu Financial LLC0$00.00%−16,054−100.0%Sold out
Turtle Creek Wealth Advisors, LLC0$00.00%−12,235−100.0%Sold out
AssuredPartners Investment Advisors, LLC0$00.00%−10,000−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−14−100.0%Sold out
Takeda Pharmaceutical Co Ltd––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed