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Stoke Therapeutics, Inc.

STOK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001623526

In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Stoke Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
198
+17 vs. Q4 2025
Shares held
71.1M
+7.28M (+11.4%) vs. Q4 2025
Total value
$2.31B
+$288.8M (+14.3%) vs. Q4 2025
New holders
44
80 more added
Sold out
27
52 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 198 institutions
Q1 2021: 106 institutionsQ2 2021: 97 institutionsQ3 2021: 90 institutionsQ4 2021: 94 institutionsQ1 2022: 99 institutionsQ2 2022: 92 institutionsQ3 2022: 105 institutionsQ4 2022: 107 institutionsQ1 2023: 97 institutionsQ2 2023: 100 institutionsQ3 2023: 97 institutionsQ4 2023: 81 institutionsQ1 2024: 103 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 130 institutionsQ1 2025: 126 institutionsQ2 2025: 134 institutionsQ3 2025: 151 institutionsQ4 2025: 183 institutionsQ1 2026: 198 institutionsQ2 2026: 197 institutions
Value heldQ1 2026: $2.31B
Q1 2021: $1.49BQ2 2021: $680.3MQ3 2021: $492.4MQ4 2021: $849.6MQ1 2022: $870.6MQ2 2022: $569.4MQ3 2022: $544.4MQ4 2022: $371.8MQ1 2023: $371.8MQ2 2023: $494.8MQ3 2023: $173.1MQ4 2023: $236.9MQ1 2024: $731.7MQ2 2024: $828.5MQ3 2024: $715.5MQ4 2024: $640.4MQ1 2025: $421.6MQ2 2025: $744.0MQ3 2025: $1.57BQ4 2025: $2.13BQ1 2026: $2.31BQ2 2026: $2.49B
Institutions holding STOK and their total value by quarter
QuarterHoldersValue
Q2 2026197$2.49B
Q1 2026198$2.31B
Q4 2025183$2.13B
Q3 2025151$1.57B
Q2 2025134$744.0M
Q1 2025126$421.6M
Q4 2024130$640.4M
Q3 2024118$715.5M
Q2 2024115$828.5M
Q1 2024103$731.7M
Q4 202381$236.9M
Q3 202397$173.1M
Q2 2023100$494.8M
Q1 202397$371.8M
Q4 2022107$371.8M
Q3 2022105$544.4M
Q2 202292$569.4M
Q1 202299$870.6M
Q4 202194$849.6M
Q3 202190$492.4M
Q2 202197$680.3M
Q1 2021106$1.49B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding STOK in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
MetLife Investment Management26,106$850.0K0.00%+786+3.1%Added
Canada Pension Plan Investment Board26,200$853.1K0.00%−9,000−25.6%Reduced
Vanguard Global Advisers, LLC26,639$867.4K0.00%+26,639New
Nomura Holdings Inc26,891$875.6K0.01%−17,461−39.4%Reduced
Profund Advisors LLC26,985$878.6K0.03%−6,403−19.2%Reduced
Los Angeles Capital Management LLC30,479$992.4K0.00%+21,273+231.1%Added
Blackstone Group Inc.30,579$995.7K0.00%+30,579New
Legal & General Group Plc32,048$1.04M0.00%−4,318−11.9%Reduced
Schroder Investment Management Group34,102$1.08M0.00%+34,102New
Mirae Asset Global ETFs Holdings Ltd.33,873$1.10M0.00%+1,358+4.2%Added
Victory Capital Management Inc33,890$1.10M0.00%−7,250−17.6%Reduced
SG Americas Securities, LLC33,996$1.11M0.00%+8,160+31.6%Added
Caption Management, LLC35,174$1.15M0.05%+35,174New
LPL Financial LLC36,047$1.17M0.00%+28,667+388.4%Added
New York State Common Retirement Fund39,158$1.27M0.00%+24,123+160.4%Added
Moran Wealth Management, LLC40,552$1.32M0.04%+40,552New
Deutsche Bank AG40,596$1.32M0.00%+7,190+21.5%Added
Alliancebernstein L.P.41,830$1.33M0.00%+1,200+3.0%Added
Platinum Investment Management Ltd40,815$1.33M0.33%00.0%Unchanged
Omers Administration Corp41,500$1.35M0.01%+41,500New
AQR Capital Management LLC46,459$1.51M0.00%+16,992+57.7%Added
Alps Advisors Inc46,498$1.51M0.01%−20,004−30.1%Reduced
Boothbay Fund Management, LLC47,307$1.54M0.04%+47,307New
State of Wisconsin Investment Board47,859$1.56M0.00%+33,040+223.0%Added
Creative Planning48,108$1.57M0.00%+6,396+15.3%Added
Schonfeld Strategic Advisors LLC49,302$1.61M0.01%−13,807−21.9%Reduced
D. E. Shaw & Co., Inc.49,972$1.63M0.00%+71+0.1%Added
Privium Fund Management B.V.50,000$1.63M0.34%−5,000−9.1%Reduced
Woodline Partners LP50,120$1.63M0.01%00.0%Unchanged
California State Teachers Retirement System51,606$1.68M0.00%+14,479+39.0%Added
EAM Investors, LLC52,000$1.69M0.20%−65,823−55.9%Reduced
BNP Paribas Arbitrage, SA56,128$1.83M0.00%+51,871+1,218.5%Added
Susquehanna International Group, LLP57,291$1.87M0.00%+11,269+24.5%Added
UBS Asset Management Americas Inc58,185$1.89M0.00%+973+1.7%Added
Rafferty Asset Management, LLC59,898$1.95M0.01%−30,295−33.6%Reduced
HighVista Strategies LLC62,617$2.04M0.56%−52,922−45.8%Reduced
Harvest Investment Services, LLC62,838$2.05M0.37%+24,491+63.9%Added
Principal Financial Group Inc63,933$2.08M0.00%−6,349−9.0%Reduced
Jane Street Group, LLC64,349$2.10M0.00%−2,763−4.1%Reduced
Rhumbline Advisers67,315$2.19M0.00%+4,901+7.9%Added
Manufacturers Life Insurance Company, The69,222$2.25M0.00%+55,672+410.9%Added
TD Asset Management Inc74,400$2.42M0.00%+74,400New
Quantedge Capital Pte Ltd78,600$2.56M1.40%−8,600−9.9%Reduced
Swiss National Bank79,100$2.58M0.00%+3,400+4.5%Added
Rhenman & Partners Asset Management AB83,000$2.70M0.33%−133,000−61.6%Reduced
Hussman Strategic Advisors, Inc.84,000$2.74M0.59%+21,000+33.3%Added
Palo Alto Investors LP84,631$2.76M0.42%+12,609+17.5%Added
EcoR1 Capital, LLC100,000$3.26M0.14%+100,000New
Nuveen, LLC108,617$3.54M0.00%+4,356+4.2%Added
Gilder Gagnon Howe & Co LLC112,627$3.67M0.04%−9,821−8.0%Reduced
Susquehanna Portfolio Strategies, LLC119,226$3.88M0.06%−7,124−5.6%Reduced
Citadel Advisors LLC123,022$4.01M0.00%+107,171+676.1%Added
DAFNA Capital Management LLC130,875$4.26M0.97%+22,000+20.2%Added
Franklin Resources Inc142,793$4.65M0.00%+10,571+8.0%Added
Bank of New York Mellon Corp143,407$4.67M0.00%+2,605+1.9%Added
Invesco Ltd.150,045$4.89M0.00%−109,498−42.2%Reduced
UBS Group AG158,304$5.15M0.00%−11,409−6.7%Reduced
First Trust Advisors LP163,459$5.32M0.00%+780+0.5%Added
Birchview Capital, LP210,000$6.84M3.89%−50,000−19.2%Reduced
T. Rowe Price Investment Management, Inc.250,913$8.17M0.01%+250,913New
JPMorgan Chase & Co265,473$8.43M0.00%−12,457−4.5%Reduced
Artisan Partners Limited Partnership315,492$10.3M0.02%+315,492New
Granahan Investment Management Inc335,586$10.9M0.53%+144,189+75.3%Added
Parkman Healthcare Partners LLC336,519$11.0M1.14%−93,636−21.8%Reduced
Vanguard Fiduciary Trust Co356,947$11.6M0.00%+356,947New
Northern Trust Corp431,630$14.1M0.00%+28,462+7.1%Added
Erste Asset Management GmbH446,000$14.2M0.13%+50,000+12.6%Added
Charles Schwab Investment Management Inc437,175$14.2M0.00%+26,269+6.4%Added
Vanguard Portfolio Management LLC462,682$15.1M0.00%+462,682New
Millennium Management LLC472,141$15.4M0.01%+472,141New
Tang Capital Management LLC500,000$16.3M0.83%00.0%Unchanged
Candriam Luxembourg S.C.A.502,020$16.3M0.08%+55,330+12.4%Added
Bank of America Corp543,095$17.7M0.00%+336,931+163.4%Added
Baillie Gifford & Co575,182$18.7M0.02%+328,282+133.0%Added
Troluce Capital Advisors LLC652,800$21.3M2.25%+652,800New
Opaleye Management Inc.700,000$22.8M3.00%+5,000+0.7%Added
MPM Oncology Impact Management LP767,038$25.0M1.93%−3,251−0.4%Reduced
Goldman Sachs Group Inc830,702$27.0M0.00%−312,035−27.3%Reduced
Assenagon Asset Management S.A.907,015$29.5M0.05%−320,708−26.1%Reduced
Dimensional Fund Advisors LP989,936$32.2M0.01%+162,797+19.7%Added
Polar Capital Holdings Plc1,132,511$36.9M0.16%−136,620−10.8%Reduced
Geode Capital Management, LLC1,322,260$43.1M0.00%+156,115+13.4%Added
Janus Henderson Group PLC1,612,781$52.5M0.03%+161,848+11.2%Added
Deerfield Management Company, L.P. (Series C)1,823,500$59.4M0.70%00.0%Unchanged
Price T Rowe Associates Inc1,934,171$63.0M0.01%+1,561,837+419.5%Added
Siren, L.L.C.1,995,347$65.0M1.80%−252,000−11.2%Reduced
State Street Corp2,276,512$74.1M0.00%−221,537−8.9%Reduced
Vanguard Capital Management LLC2,355,603$76.7M0.00%+2,355,603New
BVF Inc2,547,557$82.9M2.64%+281,883+12.4%Added
Wellington Management Group LLP3,095,700$100.8M0.02%+2,359,901+320.7%Added
Toronto Dominion Bank3,173,258$103.3M0.20%00.0%Unchanged
Baker Bros. Advisors LP3,336,697$108.6M0.62%00.0%Unchanged
Morgan Stanley3,423,280$111.5M0.01%−122,878−3.5%Reduced
Redmile Group, LLC4,164,120$135.6M8.98%+130,050+3.2%Added
Lynx1 Capital Management LP4,763,673$155.1M24.51%−641,001−11.9%Reduced
FMR LLC5,383,666$175.3M0.01%−217,254−3.9%Reduced
BlackRock, Inc.5,385,714$175.4M0.00%+173,160+3.3%Added
RTW Investments, LP5,623,525$183.1M1.82%+76,669+1.4%Added
Point72 Asset Management, L.P.0$00.00%−1,222,213−100.0%Sold out
Penserra Capital Management LLC0$00.00%−88,507−100.0%Sold out