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Stoke Therapeutics, Inc.

STOK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001623526

In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Stoke Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+17 vs. Q2 2025
Shares held
67.7M
+2.14M (+3.3%) vs. Q2 2025
Total value
$1.57B
+$830.1M (+111.6%) vs. Q2 2025
New holders
37
47 more added
Sold out
20
42 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 151 institutions
Q1 2021: 106 institutionsQ2 2021: 97 institutionsQ3 2021: 90 institutionsQ4 2021: 94 institutionsQ1 2022: 99 institutionsQ2 2022: 92 institutionsQ3 2022: 105 institutionsQ4 2022: 107 institutionsQ1 2023: 97 institutionsQ2 2023: 100 institutionsQ3 2023: 97 institutionsQ4 2023: 81 institutionsQ1 2024: 103 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 130 institutionsQ1 2025: 126 institutionsQ2 2025: 134 institutionsQ3 2025: 151 institutionsQ4 2025: 183 institutionsQ1 2026: 198 institutionsQ2 2026: 197 institutions
Value heldQ3 2025: $1.57B
Q1 2021: $1.49BQ2 2021: $680.3MQ3 2021: $492.4MQ4 2021: $849.6MQ1 2022: $870.6MQ2 2022: $569.4MQ3 2022: $544.4MQ4 2022: $371.8MQ1 2023: $371.8MQ2 2023: $494.8MQ3 2023: $173.1MQ4 2023: $236.9MQ1 2024: $731.7MQ2 2024: $828.5MQ3 2024: $715.5MQ4 2024: $640.4MQ1 2025: $421.6MQ2 2025: $744.0MQ3 2025: $1.57BQ4 2025: $2.13BQ1 2026: $2.31BQ2 2026: $2.49B
Institutions holding STOK and their total value by quarter
QuarterHoldersValue
Q2 2026197$2.49B
Q1 2026198$2.31B
Q4 2025183$2.13B
Q3 2025151$1.57B
Q2 2025134$744.0M
Q1 2025126$421.6M
Q4 2024130$640.4M
Q3 2024118$715.5M
Q2 2024115$828.5M
Q1 2024103$731.7M
Q4 202381$236.9M
Q3 202397$173.1M
Q2 2023100$494.8M
Q1 202397$371.8M
Q4 2022107$371.8M
Q3 2022105$544.4M
Q2 202292$569.4M
Q1 202299$870.6M
Q4 202194$849.6M
Q3 202190$492.4M
Q2 202197$680.3M
Q1 2021106$1.49B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding STOK in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,865,057$161.3M0.01%−547,925−7.4%Reduced
BlackRock, Inc.5,987,441$140.7M0.00%+62,874+1.1%Added
RTW Investments, LP5,123,525$120.4M1.48%00.0%Unchanged
Lynx1 Capital Management LP5,404,674$109.9M22.37%00.0%Unchanged
Baker Bros. Advisors LP4,633,838$108.9M0.79%00.0%Unchanged
Redmile Group, LLC4,175,542$98.1M9.55%−200,389−4.6%Reduced
Morgan Stanley3,537,050$83.1M0.01%−36,926−1.0%Reduced
Toronto Dominion Bank3,173,258$74.6M0.14%00.0%Unchanged
Vanguard Group Inc3,163,874$74.4M0.00%+217,616+7.4%Added
Skorpios Trust2,256,181$53.0M99.68%−1,000,000−30.7%Reduced
Siren, L.L.C.2,247,347$52.8M2.07%00.0%Unchanged
BVF Inc1,657,096$38.9M1.58%+1,657,096New
State Street Corp1,425,873$33.5M0.00%−61,283−4.1%Reduced
Polar Capital Holdings Plc1,323,470$31.1M0.15%+439,824+49.8%Added
Point72 Asset Management, L.P.1,306,698$30.7M0.07%+1,306,698New
Goldman Sachs Group Inc1,150,929$27.0M0.00%−150,452−11.6%Reduced
Geode Capital Management, LLC1,147,000$27.0M0.00%+174,079+17.9%Added
Royal Bank of Canada915,786$21.5M0.00%+771,722+535.7%Added
Assenagon Asset Management S.A.900,272$21.2M0.03%+362,299+67.3%Added
MPM Oncology Impact Management LP789,698$18.6M3.04%00.0%Unchanged
Marshall Wace, LLP768,287$18.1M0.02%−1,532,267−66.6%Reduced
Wellington Management Group LLP737,753$17.3M0.00%+600,687+438.2%Added
Opaleye Management Inc.682,017$16.0M2.27%+119,897+21.3%Added
Dimensional Fund Advisors LP678,307$15.9M0.00%+4,423+0.7%Added
Tang Capital Management LLC500,000$11.8M0.45%00.0%Unchanged
Erste Asset Management GmbH396,000$9.79M0.09%00.0%Unchanged
Northern Trust Corp414,917$9.75M0.00%−8,637−2.0%Reduced
Charles Schwab Investment Management Inc402,909$9.47M0.00%+62,130+18.2%Added
Janus Henderson Group PLC334,481$7.86M0.00%+315,581+1,669.7%Added
UBS Group AG306,037$7.19M0.00%−46,678−13.2%Reduced
Granahan Investment Management Inc253,899$5.97M0.24%−278,514−52.3%Reduced
Rhenman & Partners Asset Management AB250,000$5.88M0.65%+250,000New
Parkman Healthcare Partners LLC250,000$5.88M0.65%+250,000New
Bank of America Corp249,451$5.86M0.00%−298,639−54.5%Reduced
Schonfeld Strategic Advisors LLC238,015$5.59M0.04%+63,301+36.2%Added
Checkpoint Capital L.P.212,049$4.98M1.67%+212,049New
Birchview Capital, LP210,000$4.93M3.73%00.0%Unchanged
Invesco Ltd.208,075$4.89M0.00%+167,868+417.5%Added
DAFNA Capital Management LLC169,791$3.99M0.99%−332,181−66.2%Reduced
Gilder Gagnon Howe & Co LLC155,166$3.65M0.04%+25,595+19.8%Added
First Trust Advisors LP152,299$3.58M0.00%+152,299New
Penserra Capital Management LLC150,599$3.54M0.04%+150,599New
Susquehanna Portfolio Strategies, LLC126,350$2.97M0.05%00.0%Unchanged
Bank of New York Mellon Corp120,436$2.83M0.00%+16,663+16.1%Added
EAM Investors, LLC120,181$2.78M0.32%+120,181New
Franklin Resources Inc115,833$2.72M0.00%+34,438+42.3%Added
Barclays PLC107,723$2.53M0.00%−32,177−23.0%Reduced
Nuveen, LLC105,994$2.49M0.00%+3,526+3.4%Added
Palo Alto Investors LP105,427$2.48M0.46%−20,434−16.2%Reduced
American Century Companies Inc99,092$2.33M0.00%+71,753+262.5%Added
Woodline Partners LP95,120$2.24M0.01%00.0%Unchanged
Nomura Holdings Inc81,209$1.91M0.01%+81,209New
UBS Asset Management Americas Inc75,858$1.78M0.00%−31,382−29.3%Reduced
Fort Point Capital Partners LLC75,429$1.77M0.23%−50.0%Reduced
Swiss National Bank74,100$1.74M0.00%+12,100+19.5%Added
Citadel Advisors LLC74,056$1.74M0.00%−29,188−28.3%Reduced
Kennondale Capital Management LLC69,732$1.64M1.25%+8,549+14.0%Added
Rhumbline Advisers68,304$1.61M0.00%+1,885+2.8%Added
Millennium Management LLC61,048$1.43M0.00%+40,652+199.3%Added
D. E. Shaw & Co., Inc.52,613$1.24M0.00%+21,917+71.4%Added
Price T Rowe Associates Inc51,263$1.21M0.00%+7,528+17.2%Added
Mirae Asset Global ETFs Holdings Ltd.50,463$1.19M0.00%−2,948−5.5%Reduced
Gsa Capital Partners LLP47,583$1.12M0.09%+8,744+22.5%Added
Principal Financial Group Inc45,205$1.06M0.00%+45,205New
Alps Advisors Inc44,664$1.05M0.01%+15,234+51.8%Added
Creative Planning43,304$1.02M0.00%−911−2.1%Reduced
Alliancebernstein L.P.40,630$954.8K0.00%00.0%Unchanged
Quantedge Capital Pte Ltd40,000$940.0K0.51%+40,000New
Legal & General Group Plc37,783$887.9K0.00%+6,706+21.6%Added
Rafferty Asset Management, LLC35,327$830.2K0.00%−16,131−31.3%Reduced
Allspring Global Investments Holdings, LLC35,058$823.9K0.00%−346−1.0%Reduced
Platinum Investment Management Ltd32,901$773.2K0.05%+32,901New
California State Teachers Retirement System32,070$753.6K0.00%+20.0%Added
Campbell & CO Investment Adviser LLC30,418$714.8K0.05%+30,418New
AQR Capital Management LLC29,113$684.2K0.00%−25,705−46.9%Reduced
Wells Fargo & Company28,071$659.7K0.00%+5,066+22.0%Added
Susquehanna International Group, LLP26,792$629.6K0.00%−24,446−47.7%Reduced
Cresset Asset Management, LLC26,736$628.3K0.00%+26,736New
MetLife Investment Management25,320$595.0K0.00%+1,457+6.1%Added
JPMorgan Chase & Co24,376$572.8K0.00%−1,279−5.0%Reduced
Jain Global LLC24,340$572.0K0.01%+24,340New
Deutsche Bank AG24,230$569.4K0.00%+3,927+19.3%Added
Aviva PLC22,318$524.5K0.00%−21,637−49.2%Reduced
Ameriprise Financial Inc20,996$493.4K0.00%+20,996New
Advantage Alpha Capital Partners LP16,941$398.1K0.12%−947−5.3%Reduced
SEI Investments Co16,450$386.6K0.00%+16,450New
Quest Partners LLC15,095$354.7K0.02%+8,802+139.9%Added
Jacobs Levy Equity Management, Inc15,085$354.5K0.00%−108,397−87.8%Reduced
Manufacturers Life Insurance Company, The15,044$353.5K0.00%−55−0.4%Reduced
New York State Common Retirement Fund15,035$353.3K0.00%+4,400+41.4%Added
Dynamic Technology Lab Private Ltd13,630$320.0K0.05%+13,630New
BNP Paribas Arbitrage, SA13,401$314.9K0.00%+9,215+220.1%Added
Intech Investment Management LLC13,147$309.0K0.00%−5,070−27.8%Reduced
Great West Life Assurance Co11,978$296.0K0.00%+1,313+12.3%Added
Police & Firemen's Retirement System of New Jersey12,421$291.9K0.00%+2,863+30.0%Added
Omers Administration Corp12,100$284.4K0.00%+12,100New
Arizona State Retirement System11,294$265.4K0.00%+11,294New
Dorsey & Whitney Trust CO LLC10,815$254.2K0.01%00.0%Unchanged
Vestcor Inc10,171$239.0K0.01%+10,171New
Virtus Investment Advisers, Inc.9,627$226.2K0.06%+1,672+21.0%Added