Stoke Therapeutics, Inc.
STOK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001623526
In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Stoke Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 183
- +33 vs. Q3 2025
- Shares held
- 67.0M
- +1.55M (+2.4%) vs. Q3 2025
- Total value
- $2.13B
- +$605.0M (+39.8%) vs. Q3 2025
- New holders
- 46
- 54 more added
- Sold out
- 13
- 58 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 197 | $2.49B |
| Q1 2026 | 198 | $2.31B |
| Q4 2025 | 183 | $2.13B |
| Q3 2025 | 151 | $1.57B |
| Q2 2025 | 134 | $744.0M |
| Q1 2025 | 126 | $421.6M |
| Q4 2024 | 130 | $640.4M |
| Q3 2024 | 118 | $715.5M |
| Q2 2024 | 115 | $828.5M |
| Q1 2024 | 103 | $731.7M |
| Q4 2023 | 81 | $236.9M |
| Q3 2023 | 97 | $173.1M |
| Q2 2023 | 100 | $494.8M |
| Q1 2023 | 97 | $371.8M |
| Q4 2022 | 107 | $371.8M |
| Q3 2022 | 105 | $544.4M |
| Q2 2022 | 92 | $569.4M |
| Q1 2022 | 99 | $870.6M |
| Q4 2021 | 94 | $849.6M |
| Q3 2021 | 90 | $492.4M |
| Q2 2021 | 97 | $680.3M |
| Q1 2021 | 106 | $1.49B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 5,600,920 | $177.8M | 0.01% | −1,264,137−18.4% | Reduced |
| RTW Investments, LP | 5,546,856 | $176.1M | 1.76% | +423,331+8.3% | Added |
| Lynx1 Capital Management LP | 5,404,674 | $171.5M | 34.73% | 00.0% | Unchanged |
| BlackRock, Inc. | 5,212,554 | $165.4M | 0.00% | −774,887−12.9% | Reduced |
| Redmile Group, LLC | 4,034,070 | $128.0M | 9.43% | −141,472−3.4% | Reduced |
| Morgan Stanley | 3,546,158 | $112.6M | 0.01% | +9,108+0.3% | Added |
| Baker Bros. Advisors LP | 3,336,697 | $105.9M | 0.62% | −1,297,141−28.0% | Reduced |
| Toronto Dominion Bank | 3,173,258 | $100.7M | 0.18% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,149,239 | $100.0M | 0.00% | −14,635−0.5% | Reduced |
| State Street Corp | 2,498,049 | $79.3M | 0.00% | +1,072,176+75.2% | Added |
| BVF Inc | 2,265,674 | $71.9M | 2.42% | +608,578+36.7% | Added |
| Siren, L.L.C. | 2,247,347 | $71.3M | 2.13% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 1,823,500 | $57.9M | 0.74% | +1,823,500 | New |
| Janus Henderson Group PLC | 1,450,933 | $46.0M | 0.02% | +1,116,452+333.8% | Added |
| Polar Capital Holdings Plc | 1,269,131 | $40.3M | 0.18% | −54,339−4.1% | Reduced |
| Assenagon Asset Management S.A. | 1,227,723 | $39.0M | 0.06% | +327,451+36.4% | Added |
| Point72 Asset Management, L.P. | 1,222,213 | $38.8M | 0.06% | −84,485−6.5% | Reduced |
| Geode Capital Management, LLC | 1,166,145 | $37.0M | 0.00% | +19,145+1.7% | Added |
| Goldman Sachs Group Inc | 1,142,737 | $36.3M | 0.01% | −8,192−0.7% | Reduced |
| Dimensional Fund Advisors LP | 827,139 | $26.3M | 0.01% | +148,832+21.9% | Added |
| MPM Oncology Impact Management LP | 770,289 | $24.4M | 2.80% | −19,409−2.5% | Reduced |
| Wellington Management Group LLP | 735,799 | $23.4M | 0.00% | −1,954−0.3% | Reduced |
| Opaleye Management Inc. | 695,000 | $22.1M | 2.91% | +12,983+1.9% | Added |
| Tang Capital Management LLC | 500,000 | $15.9M | 0.78% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 446,690 | $14.2M | 0.07% | +446,690 | New |
| Parkman Healthcare Partners LLC | 430,155 | $13.7M | 1.30% | +180,155+72.1% | Added |
| Charles Schwab Investment Management Inc | 410,906 | $13.0M | 0.00% | +7,997+2.0% | Added |
| Northern Trust Corp | 403,168 | $12.8M | 0.00% | −11,749−2.8% | Reduced |
| Erste Asset Management GmbH | 396,000 | $12.6M | 0.11% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 372,334 | $11.8M | 0.00% | +321,071+626.3% | Added |
| JPMorgan Chase & Co | 277,930 | $8.82M | 0.00% | +253,554+1,040.2% | Added |
| Birchview Capital, LP | 260,000 | $8.25M | 4.83% | +50,000+23.8% | Added |
| Invesco Ltd. | 259,543 | $8.24M | 0.00% | +51,468+24.7% | Added |
| Baillie Gifford & Co | 246,900 | $7.84M | 0.01% | +246,900 | New |
| Rhenman & Partners Asset Management AB | 216,000 | $6.86M | 0.64% | −34,000−13.6% | Reduced |
| Bank of America Corp | 206,164 | $6.54M | 0.00% | −43,287−17.4% | Reduced |
| Granahan Investment Management Inc | 191,397 | $6.07M | 0.26% | −62,502−24.6% | Reduced |
| UBS Group AG | 169,713 | $5.39M | 0.00% | −136,324−44.5% | Reduced |
| First Trust Advisors LP | 162,679 | $5.16M | 0.00% | +10,380+6.8% | Added |
| Barclays PLC | 150,945 | $4.79M | 0.00% | +43,222+40.1% | Added |
| Bank of New York Mellon Corp | 140,802 | $4.47M | 0.00% | +20,366+16.9% | Added |
| Franklin Resources Inc | 132,222 | $4.20M | 0.00% | +16,389+14.1% | Added |
| Susquehanna Portfolio Strategies, LLC | 126,350 | $4.01M | 0.06% | 00.0% | Unchanged |
| Gilder Gagnon Howe & Co LLC | 122,448 | $3.89M | 0.04% | −32,718−21.1% | Reduced |
| EAM Investors, LLC | 117,823 | $3.74M | 0.42% | −2,358−2.0% | Reduced |
| HighVista Strategies LLC | 115,539 | $3.67M | 0.94% | +115,539 | New |
| American Century Companies Inc | 115,118 | $3.65M | 0.00% | +16,026+16.2% | Added |
| DAFNA Capital Management LLC | 108,875 | $3.46M | 0.80% | −60,916−35.9% | Reduced |
| Nuveen, LLC | 104,261 | $3.31M | 0.00% | −1,733−1.6% | Reduced |
| Rafferty Asset Management, LLC | 90,193 | $2.86M | 0.01% | +54,866+155.3% | Added |
| Penserra Capital Management LLC | 88,507 | $2.81M | 0.03% | −62,092−41.2% | Reduced |
| Quantedge Capital Pte Ltd | 87,200 | $2.77M | 1.32% | +47,200+118.0% | Added |
| Swiss National Bank | 75,700 | $2.40M | 0.00% | +1,600+2.2% | Added |
| Alyeska Investment Group, L.P. | 75,000 | $2.38M | 0.01% | +75,000 | New |
| Palo Alto Investors LP | 72,022 | $2.29M | 0.32% | −33,405−31.7% | Reduced |
| Principal Financial Group Inc | 70,282 | $2.23M | 0.00% | +25,077+55.5% | Added |
| Jane Street Group, LLC | 67,112 | $2.13M | 0.00% | +67,112 | New |
| Alps Advisors Inc | 66,502 | $2.11M | 0.01% | +21,838+48.9% | Added |
| Schonfeld Strategic Advisors LLC | 63,109 | $2.00M | 0.01% | −174,906−73.5% | Reduced |
| Hussman Strategic Advisors, Inc. | 63,000 | $2.00M | 0.48% | +63,000 | New |
| Rhumbline Advisers | 62,414 | $1.98M | 0.00% | −5,890−8.6% | Reduced |
| UBS Asset Management Americas Inc | 57,212 | $1.82M | 0.00% | −18,646−24.6% | Reduced |
| Privium Fund Management B.V. | 55,000 | $1.75M | 0.32% | +55,000 | New |
| Woodline Partners LP | 50,120 | $1.59M | 0.01% | −45,000−47.3% | Reduced |
| D. E. Shaw & Co., Inc. | 49,901 | $1.58M | 0.00% | −2,712−5.2% | Reduced |
| Wells Fargo & Company | 49,585 | $1.57M | 0.00% | +21,514+76.6% | Added |
| Susquehanna International Group, LLP | 46,022 | $1.46M | 0.00% | +19,230+71.8% | Added |
| Nomura Holdings Inc | 44,352 | $1.41M | 0.00% | −36,857−45.4% | Reduced |
| Creative Planning | 41,712 | $1.32M | 0.00% | −1,592−3.7% | Reduced |
| Victory Capital Management Inc | 41,140 | $1.31M | 0.00% | +41,140 | New |
| Platinum Investment Management Ltd | 40,815 | $1.30M | 0.30% | +7,914+24.1% | Added |
| Alliancebernstein L.P. | 40,630 | $1.29M | 0.00% | 00.0% | Unchanged |
| Kennondale Capital Management LLC | 38,731 | $1.23M | 0.90% | −31,001−44.5% | Reduced |
| Harvest Investment Services, LLC | 38,347 | $1.22M | 0.23% | +38,347 | New |
| California State Teachers Retirement System | 37,127 | $1.18M | 0.00% | +5,057+15.8% | Added |
| Legal & General Group Plc | 36,366 | $1.15M | 0.00% | −1,417−3.8% | Reduced |
| Canada Pension Plan Investment Board | 35,200 | $1.12M | 0.00% | +35,200 | New |
| Deutsche Bank AG | 33,406 | $1.06M | 0.00% | +9,176+37.9% | Added |
| Profund Advisors LLC | 33,388 | $1.06M | 0.03% | +33,388 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 32,515 | $1.03M | 0.00% | −17,948−35.6% | Reduced |
| AQR Capital Management LLC | 29,467 | $935.3K | 0.00% | +354+1.2% | Added |
| Readystate Asset Management LP | 29,059 | $922.3K | 0.04% | +29,059 | New |
| Cresset Asset Management, LLC | 26,325 | $835.6K | 0.00% | −411−1.5% | Reduced |
| SG Americas Securities, LLC | 25,836 | $820.0K | 0.00% | +16,840+187.2% | Added |
| MetLife Investment Management | 25,320 | $803.7K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 24,462 | $755.9K | 0.00% | −10,596−30.2% | Reduced |
| Ameriprise Financial Inc | 21,076 | $669.0K | 0.00% | +80+0.4% | Added |
| Tudor Investment Corp Et Al | 19,309 | $612.9K | 0.00% | +19,309 | New |
| Massachusetts Financial Services Co | 19,101 | $606.3K | 0.00% | +19,101 | New |
| Intech Investment Management LLC | 18,652 | $592.0K | 0.01% | +5,505+41.9% | Added |
| Diadema Partners LP | 17,181 | $545.3K | 0.32% | +17,181 | New |
| SEI Investments Co | 16,631 | $527.9K | 0.00% | +181+1.1% | Added |
| PSP Research LLC | 16,621 | $527.6K | 0.46% | +16,621 | New |
| Aviva PLC | 15,871 | $503.7K | 0.00% | −6,447−28.9% | Reduced |
| Citadel Advisors LLC | 15,851 | $503.1K | 0.00% | −58,205−78.6% | Reduced |
| Quest Partners LLC | 15,036 | $477.2K | 0.03% | −59−0.4% | Reduced |
| New York State Common Retirement Fund | 15,035 | $477.2K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 14,819 | $470.4K | 0.00% | +14,819 | New |
| Great West Life Assurance Co | 14,768 | $469.0K | 0.00% | +2,790+23.3% | Added |
| Simplex Trading, LLC | 14,281 | $453.3K | 0.01% | +14,281 | New |