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Stoke Therapeutics, Inc.

STOK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001623526

In the last 90 days, Stoke Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 197 institutions reported holding it in 13F filings for Q2 2026, worth $2.49B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Stoke Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+17 vs. Q2 2025
Shares held
67.7M
+2.14M (+3.3%) vs. Q2 2025
Total value
$1.57B
+$830.1M (+111.6%) vs. Q2 2025
New holders
37
47 more added
Sold out
20
42 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting STOK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 151 institutions
Q1 2021: 106 institutionsQ2 2021: 97 institutionsQ3 2021: 90 institutionsQ4 2021: 94 institutionsQ1 2022: 99 institutionsQ2 2022: 92 institutionsQ3 2022: 105 institutionsQ4 2022: 107 institutionsQ1 2023: 97 institutionsQ2 2023: 100 institutionsQ3 2023: 97 institutionsQ4 2023: 81 institutionsQ1 2024: 103 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 130 institutionsQ1 2025: 126 institutionsQ2 2025: 134 institutionsQ3 2025: 151 institutionsQ4 2025: 183 institutionsQ1 2026: 198 institutionsQ2 2026: 197 institutions
Value heldQ3 2025: $1.57B
Q1 2021: $1.49BQ2 2021: $680.3MQ3 2021: $492.4MQ4 2021: $849.6MQ1 2022: $870.6MQ2 2022: $569.4MQ3 2022: $544.4MQ4 2022: $371.8MQ1 2023: $371.8MQ2 2023: $494.8MQ3 2023: $173.1MQ4 2023: $236.9MQ1 2024: $731.7MQ2 2024: $828.5MQ3 2024: $715.5MQ4 2024: $640.4MQ1 2025: $421.6MQ2 2025: $744.0MQ3 2025: $1.57BQ4 2025: $2.13BQ1 2026: $2.31BQ2 2026: $2.49B
Institutions holding STOK and their total value by quarter
QuarterHoldersValue
Q2 2026197$2.49B
Q1 2026198$2.31B
Q4 2025183$2.13B
Q3 2025151$1.57B
Q2 2025134$744.0M
Q1 2025126$421.6M
Q4 2024130$640.4M
Q3 2024118$715.5M
Q2 2024115$828.5M
Q1 2024103$731.7M
Q4 202381$236.9M
Q3 202397$173.1M
Q2 2023100$494.8M
Q1 202397$371.8M
Q4 2022107$371.8M
Q3 2022105$544.4M
Q2 202292$569.4M
Q1 202299$870.6M
Q4 202194$849.6M
Q3 202190$492.4M
Q2 202197$680.3M
Q1 2021106$1.49B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Stoke Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding STOK in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Woodline Partners LP95,120$2.24M0.01%00.0%Unchanged
American Century Companies Inc99,092$2.33M0.00%+71,753+262.5%Added
Palo Alto Investors LP105,427$2.48M0.46%−20,434−16.2%Reduced
Nuveen, LLC105,994$2.49M0.00%+3,526+3.4%Added
Barclays PLC107,723$2.53M0.00%−32,177−23.0%Reduced
Franklin Resources Inc115,833$2.72M0.00%+34,438+42.3%Added
EAM Investors, LLC120,181$2.78M0.32%+120,181New
Bank of New York Mellon Corp120,436$2.83M0.00%+16,663+16.1%Added
Susquehanna Portfolio Strategies, LLC126,350$2.97M0.05%00.0%Unchanged
Penserra Capital Management LLC150,599$3.54M0.04%+150,599New
First Trust Advisors LP152,299$3.58M0.00%+152,299New
Gilder Gagnon Howe & Co LLC155,166$3.65M0.04%+25,595+19.8%Added
DAFNA Capital Management LLC169,791$3.99M0.99%−332,181−66.2%Reduced
Invesco Ltd.208,075$4.89M0.00%+167,868+417.5%Added
Birchview Capital, LP210,000$4.93M3.73%00.0%Unchanged
Checkpoint Capital L.P.212,049$4.98M1.67%+212,049New
Schonfeld Strategic Advisors LLC238,015$5.59M0.04%+63,301+36.2%Added
Bank of America Corp249,451$5.86M0.00%−298,639−54.5%Reduced
Rhenman & Partners Asset Management AB250,000$5.88M0.65%+250,000New
Parkman Healthcare Partners LLC250,000$5.88M0.65%+250,000New
Granahan Investment Management Inc253,899$5.97M0.24%−278,514−52.3%Reduced
UBS Group AG306,037$7.19M0.00%−46,678−13.2%Reduced
Janus Henderson Group PLC334,481$7.86M0.00%+315,581+1,669.7%Added
Charles Schwab Investment Management Inc402,909$9.47M0.00%+62,130+18.2%Added
Northern Trust Corp414,917$9.75M0.00%−8,637−2.0%Reduced
Erste Asset Management GmbH396,000$9.79M0.09%00.0%Unchanged
Tang Capital Management LLC500,000$11.8M0.45%00.0%Unchanged
Dimensional Fund Advisors LP678,307$15.9M0.00%+4,423+0.7%Added
Opaleye Management Inc.682,017$16.0M2.27%+119,897+21.3%Added
Wellington Management Group LLP737,753$17.3M0.00%+600,687+438.2%Added
Marshall Wace, LLP768,287$18.1M0.02%−1,532,267−66.6%Reduced
MPM Oncology Impact Management LP789,698$18.6M3.04%00.0%Unchanged
Assenagon Asset Management S.A.900,272$21.2M0.03%+362,299+67.3%Added
Royal Bank of Canada915,786$21.5M0.00%+771,722+535.7%Added
Geode Capital Management, LLC1,147,000$27.0M0.00%+174,079+17.9%Added
Goldman Sachs Group Inc1,150,929$27.0M0.00%−150,452−11.6%Reduced
Point72 Asset Management, L.P.1,306,698$30.7M0.07%+1,306,698New
Polar Capital Holdings Plc1,323,470$31.1M0.15%+439,824+49.8%Added
State Street Corp1,425,873$33.5M0.00%−61,283−4.1%Reduced
BVF Inc1,657,096$38.9M1.58%+1,657,096New
Siren, L.L.C.2,247,347$52.8M2.07%00.0%Unchanged
Skorpios Trust2,256,181$53.0M99.68%−1,000,000−30.7%Reduced
Vanguard Group Inc3,163,874$74.4M0.00%+217,616+7.4%Added
Toronto Dominion Bank3,173,258$74.6M0.14%00.0%Unchanged
Morgan Stanley3,537,050$83.1M0.01%−36,926−1.0%Reduced
Redmile Group, LLC4,175,542$98.1M9.55%−200,389−4.6%Reduced
Baker Bros. Advisors LP4,633,838$108.9M0.79%00.0%Unchanged
Lynx1 Capital Management LP5,404,674$109.9M22.37%00.0%Unchanged
RTW Investments, LP5,123,525$120.4M1.48%00.0%Unchanged
BlackRock, Inc.5,987,441$140.7M0.00%+62,874+1.1%Added
FMR LLC6,865,057$161.3M0.01%−547,925−7.4%Reduced
CI Private Wealth, LLC0$00.00%−659,834−100.0%Sold out
Cormorant Asset Management, LP0$00.00%−254,161−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−34,798−100.0%Sold out
Jane Street Group, LLC0$00.00%−34,743−100.0%Sold out
Engineers Gate Manager LP0$00.00%−33,276−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−27,285−100.0%Sold out
Squarepoint Ops LLC0$00.00%−23,458−100.0%Sold out
Verition Fund Management LLC0$00.00%−21,055−100.0%Sold out
Integrated Quantitative Investments LLC0$00.00%−19,300−100.0%Sold out
Lazard Asset Management LLC0$00.00%−13,832−100.0%Sold out
LPL Financial LLC0$00.00%−12,604−100.0%Sold out
Voya Investment Management LLC0$00.00%−11,283−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−11,099−100.0%Sold out
Profund Advisors LLC0$00.00%−10,986−100.0%Sold out
Raymond James Financial Inc0$00.00%−1,181−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,072−100.0%Sold out
Group One Trading, L.P.0$00.00%−513−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−274−100.0%Sold out
Skopos Labs, Inc.0$00.00%−69−100.0%Sold out
Mid-American Wealth Advisory Group, Inc.0$00.00%−17−100.0%Sold out