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Summit Therapeutics Inc.

SMMT
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001599298

No open-market purchases or sales by Summit Therapeutics Inc. insiders were filed in the last 90 days; 242 institutions reported holding it in 13F filings for Q2 2026, worth $1.98B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Summit Therapeutics Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
+22 vs. Q4 2025
Shares held
118.9M
+13.7M (+13.0%) vs. Q4 2025
Total value
$2.25B
+$411.9M (+22.4%) vs. Q4 2025
New holders
58
83 more added
Sold out
36
49 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SMMT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 222 institutions
Q1 2021: 38 institutionsQ2 2021: 54 institutionsQ3 2021: 51 institutionsQ4 2021: 52 institutionsQ1 2022: 48 institutionsQ2 2022: 41 institutionsQ3 2022: 42 institutionsQ4 2022: 57 institutionsQ1 2023: 86 institutionsQ2 2023: 96 institutionsQ3 2023: 91 institutionsQ4 2023: 95 institutionsQ1 2024: 103 institutionsQ2 2024: 121 institutionsQ3 2024: 164 institutionsQ4 2024: 196 institutionsQ1 2025: 202 institutionsQ2 2025: 226 institutionsQ3 2025: 232 institutionsQ4 2025: 206 institutionsQ1 2026: 222 institutionsQ2 2026: 242 institutions
Value heldQ1 2026: $2.25B
Q1 2021: $54.5MQ2 2021: $82.4MQ3 2021: $55.3MQ4 2021: $30.0MQ1 2022: $27.4MQ2 2022: $8.46MQ3 2022: $3.78MQ4 2022: $34.5MQ1 2023: $37.0MQ2 2023: $87.6MQ3 2023: $60.4MQ4 2023: $84.4MQ1 2024: $205.5MQ2 2024: $563.0MQ3 2024: $1.85BQ4 2024: $1.65BQ1 2025: $1.91BQ2 2025: $2.08BQ3 2025: $2.13BQ4 2025: $2.06BQ1 2026: $2.25BQ2 2026: $1.98B
Institutions holding SMMT and their total value by quarter
QuarterHoldersValue
Q2 2026242$1.98B
Q1 2026222$2.25B
Q4 2025206$2.06B
Q3 2025232$2.13B
Q2 2025226$2.08B
Q1 2025202$1.91B
Q4 2024196$1.65B
Q3 2024164$1.85B
Q2 2024121$563.0M
Q1 2024103$205.5M
Q4 202395$84.4M
Q3 202391$60.4M
Q2 202396$87.6M
Q1 202386$37.0M
Q4 202257$34.5M
Q3 202242$3.78M
Q2 202241$8.46M
Q1 202248$27.4M
Q4 202152$30.0M
Q3 202151$55.3M
Q2 202154$82.4M
Q1 202138$54.5M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Summit Therapeutics Inc.; share changes are against Q4 2025.

Institutions holding SMMT in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Squarepoint Ops LLC613,877$11.6M0.03%−101,533−14.2%Reduced
Standard Life Aberdeen plc665,364$12.6M0.02%−261,807−28.2%Reduced
Rock Springs Capital Management LP710,000$13.5M0.79%00.0%Unchanged
Point72 Asset Management, L.P.784,186$14.9M0.03%+784,186New
Superstring Capital Management LP892,873$16.9M12.09%+892,873New
Vanguard Fiduciary Trust Co934,394$17.7M0.00%+934,394New
TD Asset Management Inc956,894$18.1M0.01%−248,378−20.6%Reduced
Charles Schwab Investment Management Inc960,867$18.2M0.00%+68,238+7.6%Added
Two Sigma Investments, LP981,185$18.6M0.02%+402,937+69.7%Added
Pictet Asset Management Holding SA1,323,179$24.0M0.03%−60,596−4.4%Reduced
Apeiron Capital Ltd1,309,141$24.8M23.22%−1000.0%Reduced
Morgan Stanley1,650,591$31.3M0.00%+724,012+78.1%Added
D. E. Shaw & Co., Inc.2,242,229$42.5M0.03%+1,826,945+439.9%Added
Geode Capital Management, LLC3,315,854$62.9M0.00%+168,374+5.3%Added
UBS Group AG3,680,315$69.8M0.01%+2,809,596+322.7%Added
Vanguard Portfolio Management LLC5,233,252$99.2M0.01%+5,233,252New
Vanguard Capital Management LLC5,711,802$108.3M0.00%+5,711,802New
State Street Corp7,028,160$133.3M0.00%+391,799+5.9%Added
Price T Rowe Associates Inc8,277,859$156.9M0.02%−1,093,556−11.7%Reduced
BlackRock, Inc.9,653,758$183.0M0.00%+291,837+3.1%Added
FMR LLC10,853,199$205.8M0.01%−2,507,608−18.8%Reduced
Baker Bros. Advisors LP36,391,063$690.0M3.96%00.0%Unchanged
Sculptor Capital LP0$00.00%−356,900−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−338,363−100.0%Sold out
Readystate Asset Management LP0$00.00%−306,184−100.0%Sold out
Capital Fund Management S.A.0$00.00%−113,391−100.0%Sold out
HSBC Holdings PLC0$00.00%−98,766−100.0%Sold out
NEOS Investment Management LLC0$00.00%−97,217−100.0%Sold out
Polianta Ltd0$00.00%−74,700−100.0%Sold out
Mariner, LLC0$00.00%−73,497−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−59,945−100.0%Sold out
Vident Advisory, LLC0$00.00%−35,880−100.0%Sold out
IMC-Chicago, LLC0$00.00%−29,704−100.0%Sold out
First Trust Advisors LP0$00.00%−28,115−100.0%Sold out
Wealth Enhancement Advisory Services, LLC0$00.00%−20,875−100.0%Sold out
Cynosure Management, LLC0$00.00%−22,070−100.0%Sold out
Qsemble Capital Management, LP0$00.00%−16,419−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−15,407−100.0%Sold out
LPL Financial LLC0$00.00%−13,160−100.0%Sold out
State of Wyoming0$00.00%−11,533−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−11,440−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−10,700−100.0%Sold out
Sargent Investment Group, LLC0$00.00%−10,000−100.0%Sold out
Amalgamated Bank0$00.00%−9,465−100.0%Sold out
Quest Partners LLC0$00.00%−6,188−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−2,157−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−1,873−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−1,622−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−424−100.0%Sold out
Gunpowder Capital Management, LLC dba Oliver Wealth Management0$00.00%−200−100.0%Sold out
J.Safra Asset Management Corp0$00.00%−83−100.0%Sold out
UMA Financial Services, Inc.0$00.00%−55−100.0%Sold out
Assetmark, Inc0$00.00%−44−100.0%Sold out
Rialto Wealth Management, LLC0$00.00%−29−100.0%Sold out
United Financial Planning Group LLC0$00.00%−20−100.0%Sold out
JFS Wealth Advisors, LLC0$00.00%−13−100.0%Sold out
Bay Harbor Wealth Management, LLC0$00.00%−2−100.0%Sold out
SJS Investment Consulting Inc.0$00.00%−1−100.0%Sold out
Vanguard Group Inc––––Not filed
Norges Bank––––Not filed
Litman Gregory Asset Management LLC––––Not filed
ORG Partners LLC––––Not filed
Comerica Bank––––Not filed
CIBC Private Wealth Group, LLC––––Not filed