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Soleno Therapeutics Inc

SLNODelisted May 18, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001484565

Soleno Therapeutics Inc was delisted on May 18, 2026; its insiders filed their last Form 4 on May 18, 2026; 227 institutions reported holding it in 13F filings for Q1 2026, worth $2.09B in total; no superinvestor held it.

13F holders, Q4 2025

Institutional positions in Soleno Therapeutics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
248
+14 vs. Q3 2025
Shares held
64.9M
−235.8K (−0.4%) vs. Q3 2025
Total value
$3.01B
−$1.40B (−31.7%) vs. Q3 2025
New holders
63
102 more added
Sold out
49
65 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLNO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 248 institutions
Q1 2021: 63 institutionsQ2 2021: 47 institutionsQ3 2021: 39 institutionsQ4 2021: 39 institutionsQ1 2022: 41 institutionsQ2 2022: 40 institutionsQ3 2022: 22 institutionsQ4 2022: 26 institutionsQ1 2023: 21 institutionsQ2 2023: 23 institutionsQ3 2023: 54 institutionsQ4 2023: 76 institutionsQ1 2024: 98 institutionsQ2 2024: 114 institutionsQ3 2024: 142 institutionsQ4 2024: 166 institutionsQ1 2025: 217 institutionsQ2 2025: 234 institutionsQ3 2025: 240 institutionsQ4 2025: 248 institutionsQ1 2026: 227 institutionsQ2 2026: 0 institutions
Value heldQ4 2025: $3.01B
Q1 2021: $41.2MQ2 2021: $33.6MQ3 2021: $27.1MQ4 2021: $11.8MQ1 2022: $11.2MQ2 2022: $8.80MQ3 2022: $5.23MQ4 2022: $6.00MQ1 2023: $7.06MQ2 2023: $21.8MQ3 2023: $598.8MQ4 2023: $1.26BQ1 2024: $1.52BQ2 2024: $1.79BQ3 2024: $2.38BQ4 2024: $2.29BQ1 2025: $3.90BQ2 2025: $4.75BQ3 2025: $4.41BQ4 2025: $3.01BQ1 2026: $2.09BQ2 2026: $0
Institutions holding SLNO and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 2026227$2.09B
Q4 2025248$3.01B
Q3 2025240$4.41B
Q2 2025234$4.75B
Q1 2025217$3.90B
Q4 2024166$2.29B
Q3 2024142$2.38B
Q2 2024114$1.79B
Q1 202498$1.52B
Q4 202376$1.26B
Q3 202354$598.8M
Q2 202323$21.8M
Q1 202321$7.06M
Q4 202226$6.00M
Q3 202222$5.23M
Q2 202240$8.80M
Q1 202241$11.2M
Q4 202139$11.8M
Q3 202139$27.1M
Q2 202147$33.6M
Q1 202163$41.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Soleno Therapeutics Inc; share changes are against Q3 2025.

Institutions holding SLNO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC8,079,304$374.1M0.02%+79,622+1.0%Added
Janus Henderson Group PLC7,178,354$332.3M0.15%+1,122,015+18.5%Added
BlackRock, Inc.3,871,639$179.3M0.00%+379,387+10.9%Added
Wellington Management Group LLP3,322,799$153.8M0.03%+1,010,704+43.7%Added
Price T Rowe Associates Inc3,318,698$153.7M0.02%−584,208−15.0%Reduced
Vanguard Group Inc3,060,361$141.7M0.00%+253,212+9.0%Added
Avoro Capital Advisors LLC2,900,000$134.3M1.32%+322,223+12.5%Added
State Street Corp2,649,626$122.7M0.00%+476,590+21.9%Added
Nantahala Capital Management, LLC1,314,002$60.8M3.63%+450,239+52.1%Added
Millennium Management LLC1,236,321$57.2M0.04%+256,495+26.2%Added
Commodore Capital LP1,200,000$55.6M3.70%−150,000−11.1%Reduced
Braidwell LP1,187,859$55.0M1.76%−94,130−7.3%Reduced
Geode Capital Management, LLC1,163,338$53.9M0.00%+78,386+7.2%Added
Polar Capital Holdings Plc1,136,929$52.6M0.24%−54,194−4.5%Reduced
Woodline Partners LP1,111,778$51.5M0.20%+840,946+310.5%Added
Deep Track Capital, LP1,000,000$46.3M1.06%+1,000,000New
Goldman Sachs Group Inc913,050$42.3M0.01%+357,612+64.4%Added
Vivo Capital, LLC894,909$41.4M2.68%−1,383,294−60.7%Reduced
Invesco Ltd.875,019$40.5M0.00%−625,506−41.7%Reduced
Readystate Asset Management LP874,447$40.5M1.79%+668,640+324.9%Added
Franklin Resources Inc823,958$38.1M0.01%−11,793−1.4%Reduced
Pictet Asset Management Holding SA624,128$28.9M0.03%+73,504+13.3%Added
Bank of New York Mellon Corp621,811$28.8M0.01%−5,416−0.9%Reduced
Hood River Capital Management LLC618,005$28.6M0.31%+4,611+0.8%Added
Artia Global Partners LP533,698$24.7M3.97%−138,478−20.6%Reduced
Squarepoint Ops LLC468,654$21.7M0.04%+399,700+579.7%Added
Schroder Investment Management Group449,848$20.8M0.02%+169,552+60.5%Added
Emerald Advisers, LLC412,651$19.1M0.59%−215,105−34.3%Reduced
Charles Schwab Investment Management Inc401,186$18.6M0.00%+11,830+3.0%Added
Great Point Partners LLC400,000$18.5M6.00%+175,000+77.8%Added
Kingdon Capital Management, L.L.C.399,900$18.5M2.83%+98,900+32.9%Added
Assenagon Asset Management S.A.384,166$17.8M0.03%+384,166New
Northern Trust Corp365,418$16.9M0.00%+11,184+3.2%Added
Catalio Capital Management, LP360,340$16.7M2.95%−57,905−13.8%Reduced
Integral Health Asset Management, LLC325,000$15.0M0.76%+325,000New
Citadel Advisors LLC308,830$14.3M0.01%−141,296−31.4%Reduced
Logos Global Management LP300,000$13.9M0.93%+300,000New
Morgan Stanley287,639$13.3M0.00%+121,794+73.4%Added
Standard Life Aberdeen plc287,456$13.3M0.02%+287,456New
Qube Research & Technologies Ltd287,293$13.3M0.02%+221,521+336.8%Added
Penn Capital Management Co Inc275,782$12.8M1.02%+275,782New
PFM Health Sciences, LP247,893$11.5M1.16%+4,492+1.8%Added
Rock Springs Capital Management LP247,053$11.4M0.59%+92,525+59.9%Added
Susquehanna International Group, LLP244,358$11.3M0.02%+228,340+1,425.5%Added
Emerald Mutual Fund Advisers Trust232,485$10.8M0.52%−147,415−38.8%Reduced
Balyasny Asset Management LLC227,751$10.5M0.02%−432,814−65.5%Reduced
Alyeska Investment Group, L.P.217,500$10.1M0.03%+25,000+13.0%Added
BNP Paribas Arbitrage, SA212,818$9.85M0.01%+204,710+2,524.8%Added
SummitTX Capital, L.P.211,727$9.80M0.30%+78,911+59.4%Added
Bank of America Corp208,595$9.66M0.00%+46,497+28.7%Added
Skandinaviska Enskilda Banken AB (publ)187,475$8.68M0.03%+64,736+52.7%Added
New York State Common Retirement Fund185,317$8.58M0.01%+169,717+1,087.9%Added
Clark Capital Management Group, Inc.180,250$8.35M0.05%+180,250New
UBS Group AG169,506$7.85M0.00%+11,198+7.1%Added
Ally Bridge Group (NY) LLC168,029$7.78M12.35%−134,454−44.5%Reduced
Engineers Gate Manager LP168,005$7.78M0.09%+168,005New
Barclays PLC157,685$7.30M0.00%−13,295−7.8%Reduced
Buckley Capital Advisors, LLC149,150$6.91M6.01%+149,150New
Brevan Howard Capital Management LP147,800$6.84M0.13%+133,540+936.5%Added
Capital World Investors145,522$6.74M0.00%−678,992−82.4%Reduced
Deutsche Bank AG141,982$6.57M0.00%+5,205+3.8%Added
Jane Street Group, LLC141,740$6.56M0.01%+141,740New
Granahan Investment Management Inc137,592$6.37M0.27%+28,339+25.9%Added
Sphera Funds Management Ltd.136,314$6.31M1.32%+94,708+227.6%Added
Eagle Health Investments LP135,100$6.26M1.37%+135,100New
HighVista Strategies LLC135,069$6.25M1.61%+116,369+622.3%Added
Trexquant Investment LP132,912$6.15M0.05%+122,576+1,185.9%Added
Seven Fleet Capital Management LP130,079$6.02M4.08%+130,079New
Royce & Associates LP129,043$5.97M0.06%+98,056+316.4%Added
Nan Fung Trinity (HK) Ltd123,850$5.73M0.45%00.0%Unchanged
Frontier Capital Management Co LLC119,695$5.54M0.06%+1,351+1.1%Added
Peregrine Capital Management LLC119,564$5.54M0.17%+26,559+28.6%Added
Centiva Capital, LP118,804$5.50M0.33%+118,804New
Silverarc Capital Management, LLC117,485$5.44M0.79%+117,485New
JPMorgan Chase & Co115,517$5.35M0.00%−291,927−71.6%Reduced
Nuveen, LLC100,622$4.66M0.00%+5,997+6.3%Added
Rafferty Asset Management, LLC95,597$4.43M0.02%+3,122+3.4%Added
Swiss National Bank89,100$4.13M0.00%+12,400+16.2%Added
Mutual of America Capital Management LLC83,166$3.85M0.04%+4,333+5.5%Added
State of Wisconsin Investment Board72,482$3.36M0.01%+32,290+80.3%Added
UBS Asset Management Americas Inc72,360$3.35M0.00%+13,968+23.9%Added
National Philanthropic Trust69,545$3.22M0.03%+69,545New
Ikarian Capital, LLC68,823$3.19M0.41%+12,877+23.0%Added
SEI Investments Co67,330$3.12M0.00%−46,503−40.9%Reduced
HealthInvest Partners AB62,735$2.90M0.93%+2,579+4.3%Added
KVP Capital Advisors, LP59,700$2.76M2.86%+59,700New
AQR Capital Management LLC58,752$2.72M0.00%+21,655+58.4%Added
Rhumbline Advisers55,068$2.55M0.00%−4,792−8.0%Reduced
Jump Financial, LLC54,487$2.52M0.03%+54,487New
DV Trading LLC54,000$2.50M0.22%+54,000New
Wells Fargo & Company52,643$2.44M0.00%+22,163+72.7%Added
Simplex Trading, LLC49,108$2.27M0.06%+23,999+95.6%Added
Lazard Asset Management LLC48,445$2.24M0.00%−8,000−14.2%Reduced
Russell Investments Group, Ltd.46,678$2.16M0.00%−47,665−50.5%Reduced
Moody Aldrich Partners LLC46,306$2.14M0.40%−4,968−9.7%Reduced
Winton Group Ltd44,200$2.05M0.07%+44,200New
Boothbay Fund Management, LLC43,862$2.03M0.05%+9,632+28.1%Added
Banque Pictet & Cie SA43,796$2.03M0.02%+43,796New
Alliancebernstein L.P.42,290$1.96M0.00%00.0%Unchanged
Caption Management, LLC42,100$1.95M0.09%−327,900−88.6%Reduced