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SAB Biotherapeutics, Inc.

SABS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001833214

No open-market purchases or sales by SAB Biotherapeutics, Inc. insiders were filed in the last 90 days; 87 institutions reported holding it in 13F filings for Q2 2026, worth $266.8M in total; no superinvestor holds it.

Other share classesSABSW

13F holders, Q4 2025

Institutional positions in SAB Biotherapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
+14 vs. Q3 2025
Shares held
36.3M
+8.32M (+29.7%) vs. Q3 2025
Total value
$135.9M
+$79.6M (+141.3%) vs. Q3 2025
New holders
21
11 more added
Sold out
7
4 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SABS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 48 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 1 institutionQ4 2021: 34 institutionsQ1 2022: 27 institutionsQ2 2022: 37 institutionsQ3 2022: 40 institutionsQ4 2022: 38 institutionsQ1 2023: 39 institutionsQ2 2023: 38 institutionsQ3 2023: 34 institutionsQ4 2023: 42 institutionsQ1 2024: 24 institutionsQ2 2024: 22 institutionsQ3 2024: 25 institutionsQ4 2024: 25 institutionsQ1 2025: 26 institutionsQ2 2025: 25 institutionsQ3 2025: 34 institutionsQ4 2025: 48 institutionsQ1 2026: 76 institutionsQ2 2026: 87 institutions
Value heldQ4 2025: $135.9M
Q1 2021: $0Q2 2021: $0Q3 2021: $605.0KQ4 2021: $25.4MQ1 2022: $6.71MQ2 2022: $4.45MQ3 2022: $2.32MQ4 2022: $2.42MQ1 2023: $1.71MQ2 2023: $3.28MQ3 2023: $2.41MQ4 2023: $24.5MQ1 2024: $15.2MQ2 2024: $9.69MQ3 2024: $8.48MQ4 2024: $10.1MQ1 2025: $2.99MQ2 2025: $3.37MQ3 2025: $56.3MQ4 2025: $135.9MQ1 2026: $265.0MQ2 2026: $266.8M
Institutions holding SABS and their total value by quarter
QuarterHoldersValue
Q2 202687$266.8M
Q1 202676$265.0M
Q4 202548$135.9M
Q3 202534$56.3M
Q2 202525$3.37M
Q1 202526$2.99M
Q4 202425$10.1M
Q3 202425$8.48M
Q2 202422$9.69M
Q1 202424$15.2M
Q4 202342$24.5M
Q3 202334$2.41M
Q2 202338$3.28M
Q1 202339$1.71M
Q4 202238$2.42M
Q3 202240$2.32M
Q2 202237$4.45M
Q1 202227$6.71M
Q4 202134$25.4M
Q3 20211$605.0K
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding SAB Biotherapeutics, Inc.; share changes are against Q3 2025.

Institutions holding SABS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vivo Capital, LLC11,420,000$42.7M2.76%00.0%Unchanged
Ra Capital Management, L.P.4,401,500$16.5M0.17%00.0%Unchanged
Commodore Capital LP4,401,500$16.5M1.10%00.0%Unchanged
Woodline Partners LP2,850,881$10.7M0.04%00.0%Unchanged
Spruce Street Capital LP2,198,502$8.22M2.72%+2,198,502New
Sessa Capital IM, L.P.2,198,457$8.22M0.16%00.0%Unchanged
Blackstone Group Inc.2,143,585$8.02M0.03%+2,143,585New
Vanguard Group Inc1,847,136$6.91M0.00%+1,481,383+405.0%Added
Perceptive Advisors LLC803,210$3.00M0.06%+803,210New
Propel Bio Management, LLC652,881$2.44M2.08%+652,881New
Jefferies Financial Group Inc.580,328$2.17M0.02%+580,328New
Balyasny Asset Management LLC475,439$1.78M0.00%+475,439New
Millennium Management LLC324,090$1.21M0.00%+324,090New
HB Wealth Management, LLC307,500$1.15M0.01%00.0%Unchanged
Ameriprise Financial Inc283,645$1.06M0.00%+283,645New
Marshall Wace, LLP236,460$884.4K0.00%+236,460New
Simplify Asset Management Inc.208,227$778.8K0.01%+208,227New
AWM Investment Company, Inc.200,000$748.0K0.07%00.0%Unchanged
StemPoint Capital LP146,558$548.1K0.09%+146,558New
Geode Capital Management, LLC119,517$447.0K0.00%+33,799+39.4%Added
ExodusPoint Capital Management, LP86,113$322.1K0.00%+86,113New
Goldman Sachs Group Inc51,348$192.0K0.00%+40,127+357.6%Added
Pathstone Holdings, LLC50,650$189.4K0.00%00.0%Unchanged
Omers Administration Corp42,000$157.1K0.00%+42,000New
Qube Research & Technologies Ltd31,147$116.5K0.00%+31,147New
Citigroup Inc29,974$112.1K0.00%+29,142+3,502.6%Added
Verition Fund Management LLC26,867$100.5K0.00%+26,867New
ADAR1 Capital Management, LLC26,344$98.5K0.01%+11,344+75.6%Added
Persistent Asset Partners Ltd19,790$74.0K0.04%+19,790New
Colony Group, LLC19,201$71.8K0.00%+19,201New
First PREMIER Bank18,986$71.0K0.02%00.0%Unchanged
Citadel Advisors LLC17,650$66.0K0.00%+17,650New
BlackRock, Inc.17,239$64.5K0.00%+10,900+172.0%Added
Northern Trust Corp16,412$61.4K0.00%+5,025+44.1%Added
Fifth Lane Capital, LP15,000$56.1K0.07%+15,000New
State Street Corp13,122$49.1K0.00%+13,122New
Kestra Advisory Services, LLC11,550$43.2K0.00%−380−3.2%Reduced
Bank of America Corp10,613$39.7K0.00%+10,539+14,241.9%Added
Caxton Corp10,527$39.4K0.92%−408−3.7%Reduced
State of Wyoming8,971$33.6K0.00%+8,971New
UBS Group AG7,398$27.7K0.00%−5,823−44.0%Reduced
Advisor Group Holdings, Inc.5,024$18.8K0.00%+200+4.1%Added
Morgan Stanley4,262$15.9K0.00%+4,094+2,436.9%Added
JPMorgan Chase & Co1,990$7.44K0.00%+1,903+2,187.4%Added
MAI Capital Management217$8120.00%00.0%Unchanged
Gs Investments, Inc.200$7480.00%00.0%Unchanged
SBI Securities Co., Ltd.50$1870.00%−2−3.8%Reduced
Harbour Investments, Inc.50$1870.00%00.0%Unchanged
BVF Inc0$00.00%−932,697−100.0%Sold out
Sphera Funds Management Ltd.0$00.00%−566,395−100.0%Sold out
Renaissance Technologies LLC0$00.00%−80,840−100.0%Sold out
Virtu Financial LLC0$00.00%−19,982−100.0%Sold out
Kovitz Investment Group Partners, LLC0$00.00%−19,201−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−15,781−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−1,560−100.0%Sold out