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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Relay Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
244
+22 vs. Q4 2025
Shares held
184.2M
+20.7M (+12.6%) vs. Q4 2025
Total value
$1.83B
+$448.7M (+32.4%) vs. Q4 2025
New holders
51
95 more added
Sold out
29
53 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 244 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ1 2026: $1.83B
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding RLAY in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
OP Asset Management Ltd29,217$290.7K0.00%+29,217New
Citigroup Inc29,754$296.1K0.00%−1,176−3.8%Reduced
Vanguard Investments Australia, Ltd.30,117$299.7K0.00%+30,117New
JustInvest LLC31,582$314.2K0.00%+3,995+14.5%Added
Intech Investment Management LLC31,617$314.6K0.00%−21,584−40.6%Reduced
China Universal Asset Management Co., Ltd.31,716$315.6K0.02%+3,473+12.3%Added
Skopos Labs, Inc.32,577$324.1K0.01%+5,436+20.0%Added
Arizona State Retirement System33,325$331.6K0.00%−206−0.6%Reduced
Gotham Asset Management, LLC33,606$334.4K0.00%+33,606New
Virtus Investment Advisers, Inc.33,957$337.9K0.09%+827+2.5%Added
Valeo Financial Advisors, LLC35,714$355.4K0.01%+35,714New
Mariner, LLC36,096$358.4K0.00%+36,096New
SEI Investments Co36,130$359.5K0.00%+10,500+41.0%Added
Cresset Asset Management, LLC36,495$363.1K0.00%−589−1.6%Reduced
Captrust Financial Advisors36,769$365.8K0.00%+1,203+3.4%Added
Police & Firemen's Retirement System of New Jersey37,005$368.2K0.00%00.0%Unchanged
Brandywine Managers, LLC38,429$382.4K0.23%00.0%Unchanged
BNP Paribas Arbitrage, SA39,467$392.7K0.00%+19,463+97.3%Added
LPL Financial LLC40,463$402.6K0.00%+6,319+18.5%Added
State of New Jersey Common Pension Fund D41,464$412.6K0.00%+41,464New
Intellectus Partners, LLC42,225$420.1K0.09%−1,700−3.9%Reduced
Barclays PLC45,267$450.4K0.00%−368,876−89.1%Reduced
New York State Common Retirement Fund45,799$455.7K0.00%00.0%Unchanged
Headlands Technologies LLC47,626$473.9K0.05%+47,626New
Aquatic Capital Management LLC48,120$478.8K0.01%+48,120New
Algert Global LLC48,510$482.7K0.01%−97,990−66.9%Reduced
Franklin Resources Inc48,915$486.7K0.00%00.0%Unchanged
Bank of Montreal52,943$526.8K0.00%−3,511−6.2%Reduced
DekaBank Deutsche Girozentrale60,000$591.0K0.00%00.0%Unchanged
Wellington Management Group LLP59,508$592.1K0.00%+59,508New
Prelude Capital Management, LLC61,899$615.9K0.05%+61,899New
J. Goldman & Co LP63,637$633.2K0.03%+51,086+407.0%Added
Janus Henderson Group PLC65,573$652.1K0.00%+28,700+77.8%Added
Zurcher Kantonalbank (Zurich Cantonalbank)66,739$664.1K0.00%+9,505+16.6%Added
Profund Advisors LLC68,170$678.3K0.02%−4,416−6.1%Reduced
Wealth Enhancement Advisory Services, LLC55,384$694.5K0.00%+7,740+16.2%Added
CWM, LLC69,959$696.1K0.00%+2,356+3.5%Added
Schonfeld Strategic Advisors LLC71,880$715.2K0.01%+10,027+16.2%Added
Vanguard Global Advisers, LLC75,079$747.0K0.00%+75,079New
Mirae Asset Global ETFs Holdings Ltd.76,661$756.4K0.00%−180.0%Reduced
Allspring Global Investments Holdings, LLC72,739$783.4K0.00%+7,292+11.1%Added
MetLife Investment Management79,024$786.3K0.00%+1,488+1.9%Added
Victory Capital Management Inc79,994$795.9K0.00%+64,978+432.7%Added
Legal & General Group Plc82,056$816.5K0.00%−27,152−24.9%Reduced
Vanguard Asset Management, Ltd82,300$818.9K0.00%+82,300New
Himension Fund94,169$937.0K0.07%−10,784−10.3%Reduced
Trexquant Investment LP94,248$937.8K0.01%−377,797−80.0%Reduced
ICONIQ Capital, LLC94,697$942.2K0.02%00.0%Unchanged
Creative Planning101,349$1.01M0.00%+15,513+18.1%Added
Wells Fargo & Company109,952$1.09M0.00%−47,940−30.4%Reduced
Man Group plc112,843$1.12M0.00%+25,806+29.6%Added
Alliancebernstein L.P.145,251$1.23M0.00%00.0%Unchanged
Deutsche Bank AG129,612$1.29M0.00%+5,618+4.5%Added
Engineers Gate Manager LP141,452$1.41M0.02%+63,084+80.5%Added
Sanctuary Advisors, LLC143,816$1.43M0.01%+1,588+1.1%Added
Alps Advisors Inc145,490$1.45M0.01%+3,169+2.2%Added
Susquehanna International Group, LLP147,158$1.46M0.00%−75,771−34.0%Reduced
Rafferty Asset Management, LLC150,618$1.50M0.01%−43,138−22.3%Reduced
Tema ETFs LLC154,100$1.53M0.10%+42,545+38.1%Added
Toroso Investments, LLC154,100$1.53M0.00%+154,100New
State of Wisconsin Investment Board162,236$1.61M0.00%+61,076+60.4%Added
California State Teachers Retirement System174,099$1.73M0.00%+56,422+47.9%Added
Citadel Advisors LLC176,265$1.75M0.00%+62,122+54.4%Added
Raiffeisen Bank International AG190,000$1.78M0.03%−60,000−24.0%Reduced
Squarepoint Ops LLC180,298$1.79M0.00%+86,088+91.4%Added
Polygon Management Ltd.181,543$1.81M0.35%+181,543New
Advisor Group Holdings, Inc.186,123$1.85M0.00%−265−0.1%Reduced
XTX Topco Ltd188,940$1.88M0.03%+31,534+20.0%Added
SG Americas Securities, LLC197,535$1.97M0.00%−23,414−10.6%Reduced
Ieq Capital, LLC205,310$2.04M0.01%+43,025+26.5%Added
Manufacturers Life Insurance Company, The209,707$2.09M0.00%+32,221+18.2%Added
UBS Asset Management Americas Inc210,468$2.09M0.00%+620+0.3%Added
TD Asset Management Inc214,170$2.13M0.00%+32,182+17.7%Added
Voya Investment Management LLC216,052$2.15M0.00%+191,477+779.2%Added
Rhumbline Advisers216,933$2.16M0.00%+1,192+0.6%Added
Swiss National Bank238,000$2.37M0.00%00.0%Unchanged
Seven Fleet Capital Management LP257,738$2.56M0.81%+184,738+253.1%Added
Eversept Partners, LP270,705$2.69M0.18%−218,432−44.7%Reduced
Exome Asset Management LLC278,302$2.77M1.63%+278,302New
Acadian Asset Management LLC290,352$2.89M0.00%−166,296−36.4%Reduced
Nuveen, LLC302,196$3.01M0.00%+1,732+0.6%Added
Hudson Bay Capital Management LP311,330$3.10M0.02%−140,170−31.0%Reduced
Susquehanna Portfolio Strategies, LLC339,080$3.37M0.05%00.0%Unchanged
Raymond James Financial Inc346,317$3.45M0.00%+86,906+33.5%Added
Millennium Management LLC347,733$3.46M0.00%−549,176−61.2%Reduced
Ameriprise Financial Inc356,924$3.55M0.00%+356,924New
Rhenman & Partners Asset Management AB360,000$3.58M0.44%−100,000−21.7%Reduced
Bank of New York Mellon Corp382,920$3.81M0.00%+4,217+1.1%Added
Affinity Asset Advisors, LLC400,000$3.98M0.23%+400,000New
Sphera Funds Management Ltd.408,436$4.06M0.70%+408,436New
HighVista Strategies LLC421,881$4.20M1.16%−123,198−22.6%Reduced
Jane Street Group, LLC423,536$4.21M0.00%+347,060+453.8%Added
American Century Companies Inc440,185$4.38M0.00%+7,692+1.8%Added
Bessemer Group Inc457,869$4.56M0.01%00.0%Unchanged
Longaeva Partners L.P.470,544$4.68M0.23%+470,544New
Timothy G. Youngquist 2020 Irrevocable Trust499,058$4.97M2.43%00.0%Unchanged
UBS Group AG527,611$5.25M0.00%+231,594+78.2%Added
Elmind Capital, LP536,946$5.34M1.52%00.0%Unchanged
ArrowMark Colorado Holdings LLC541,124$5.38M0.14%00.0%Unchanged
JPMorgan Chase & Co647,518$6.05M0.00%+221,560+52.0%Added