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Relay Therapeutics, Inc.

RLAY
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001812364

In the last 90 days, Relay Therapeutics, Inc. insiders filed 0 open-market purchases and 14 sales; 259 institutions reported holding it in 13F filings for Q2 2026, worth $4.58B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Relay Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+1 vs. Q1 2025
Shares held
171.0M
+3.66M (+2.2%) vs. Q1 2025
Total value
$591.8M
+$153.7M (+35.1%) vs. Q1 2025
New holders
35
74 more added
Sold out
34
55 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RLAY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 208 institutions
Q1 2021: 137 institutionsQ2 2021: 125 institutionsQ3 2021: 132 institutionsQ4 2021: 131 institutionsQ1 2022: 140 institutionsQ2 2022: 148 institutionsQ3 2022: 162 institutionsQ4 2022: 165 institutionsQ1 2023: 157 institutionsQ2 2023: 161 institutionsQ3 2023: 172 institutionsQ4 2023: 177 institutionsQ1 2024: 189 institutionsQ2 2024: 179 institutionsQ3 2024: 195 institutionsQ4 2024: 200 institutionsQ1 2025: 208 institutionsQ2 2025: 208 institutionsQ3 2025: 199 institutionsQ4 2025: 227 institutionsQ1 2026: 244 institutionsQ2 2026: 259 institutions
Value heldQ2 2025: $591.8M
Q1 2021: $2.96BQ2 2021: $3.26BQ3 2021: $2.89BQ4 2021: $3.41BQ1 2022: $3.38BQ2 2022: $2.02BQ3 2022: $2.76BQ4 2022: $1.91BQ1 2023: $2.16BQ2 2023: $1.64BQ3 2023: $1.10BQ4 2023: $1.40BQ1 2024: $1.10BQ2 2024: $826.8MQ3 2024: $1.16BQ4 2024: $675.8MQ1 2025: $438.1MQ2 2025: $591.8MQ3 2025: $867.4MQ4 2025: $1.47BQ1 2026: $1.83BQ2 2026: $4.58B
Institutions holding RLAY and their total value by quarter
QuarterHoldersValue
Q2 2026259$4.58B
Q1 2026244$1.83B
Q4 2025227$1.47B
Q3 2025199$867.4M
Q2 2025208$591.8M
Q1 2025208$438.1M
Q4 2024200$675.8M
Q3 2024195$1.16B
Q2 2024179$826.8M
Q1 2024189$1.10B
Q4 2023177$1.40B
Q3 2023172$1.10B
Q2 2023161$1.64B
Q1 2023157$2.16B
Q4 2022165$1.91B
Q3 2022162$2.76B
Q2 2022148$2.02B
Q1 2022140$3.38B
Q4 2021131$3.41B
Q3 2021132$2.89B
Q2 2021125$3.26B
Q1 2021137$2.96B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Relay Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding RLAY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
SB Investment Advisers (UK) Ltd27,904,963$96.6M0.77%00.0%Unchanged
BlackRock, Inc.13,954,486$48.3M0.00%−524,312−3.6%Reduced
Point72 Asset Management, L.P.13,445,704$46.5M0.11%+2,618,637+24.2%Added
Commodore Capital LP13,350,000$46.2M3.26%+13,350,000New
Casdin Capital, LLC11,398,574$39.4M3.59%+2,300,000+25.3%Added
Vanguard Group Inc9,379,851$32.5M0.00%−2,725,569−22.5%Reduced
Bellevue Group AG8,230,870$28.5M0.63%+853,578+11.6%Added
Tang Capital Management LLC8,068,058$27.9M1.41%00.0%Unchanged
State Street Corp5,202,791$18.0M0.00%+43,599+0.8%Added
JPMorgan Chase & Co4,338,403$15.0M0.00%−571,368−11.6%Reduced
Nextech Invest, Ltd.3,846,409$13.3M2.52%00.0%Unchanged
Geode Capital Management, LLC3,229,666$11.2M0.00%+159,548+5.2%Added
Kynam Capital Management, LP2,887,014$9.99M1.08%−176,278−5.8%Reduced
Price T Rowe Associates Inc2,875,936$9.95M0.00%−601,855−17.3%Reduced
Dimensional Fund Advisors LP2,789,460$9.65M0.00%−9,631−0.3%Reduced
MPM Oncology Impact Management LP2,282,680$7.90M1.37%−13,244−0.6%Reduced
Goldman Sachs Group Inc1,935,167$6.70M0.00%−142,828−6.9%Reduced
Millennium Management LLC1,870,362$6.47M0.01%−1,072,513−36.4%Reduced
Alphabet Inc.1,568,753$5.43M0.25%00.0%Unchanged
Renaissance Technologies LLC1,508,210$5.22M0.01%−767,900−33.7%Reduced
Morgan Stanley1,422,346$4.92M0.00%−170,840−10.7%Reduced
Bank of America Corp1,320,130$4.57M0.00%+765,702+138.1%Added
Northern Trust Corp1,162,092$4.02M0.00%+19,164+1.7%Added
Baker Bros. Advisors LP1,160,117$4.01M0.04%00.0%Unchanged
Two Sigma Advisers, LP1,139,800$3.94M0.01%+388,600+51.7%Added
Charles Schwab Investment Management Inc1,106,260$3.83M0.00%+41,402+3.9%Added
AQR Capital Management LLC1,083,465$3.75M0.00%+718,519+196.9%Added
Two Sigma Investments, LP1,023,384$3.54M0.01%+179,528+21.3%Added
Woodline Partners LP1,018,115$3.52M0.02%−500,446−33.0%Reduced
Algert Global LLC1,002,016$3.47M0.07%+70,765+7.6%Added
Foresite Capital Management IV, LLC1,000,000$3.46M2.79%00.0%Unchanged
Norges Bank835,874$2.89M0.00%−3,799,263−82.0%Reduced
Acadian Asset Management LLC794,619$2.75M0.01%+112,591+16.5%Added
Ikarian Capital, LLC743,308$2.57M0.85%00.0%Unchanged
Polygon Management Ltd.699,000$2.42M0.44%+80,000+12.9%Added
Bessemer Group Inc584,530$2.02M0.00%00.0%Unchanged
Barclays PLC556,522$1.93M0.00%+87,351+18.6%Added
ArrowMark Colorado Holdings LLC541,124$1.87M0.03%00.0%Unchanged
Eversept Partners, LP533,409$1.85M0.19%+533,409New
Rhenman & Partners Asset Management AB460,000$1.59M0.20%00.0%Unchanged
Private Capital Advisors, Inc.441,739$1.53M0.19%+341,739+341.7%Added
Royal Bank of Canada438,032$1.52M0.00%+425,957+3,527.6%Added
Ameriprise Financial Inc410,896$1.42M0.00%+38,543+10.4%Added
UBS Asset Management Americas Inc408,902$1.41M0.00%+107,352+35.6%Added
Franklin Resources Inc394,122$1.36M0.00%+223,042+130.4%Added
Bank of New York Mellon Corp358,371$1.24M0.00%+28,466+8.6%Added
Prudential Financial Inc358,225$1.24M0.00%−35,150−8.9%Reduced
American Century Companies Inc349,420$1.21M0.00%+40,668+13.2%Added
Susquehanna International Group, LLP306,069$1.06M0.00%+49,286+19.2%Added
Man Group plc298,510$1.03M0.00%+92,789+45.1%Added
HarbourVest Partners LLC296,402$1.03M1.12%00.0%Unchanged
Verition Fund Management LLC290,599$1.01M0.01%+151,355+108.7%Added
Nuveen, LLC288,450$998.0K0.00%−31,945−10.0%Reduced
Susquehanna Fundamental Investments, LLC279,212$966.1K0.03%−76,953−21.6%Reduced
Invesco Ltd.273,383$945.9K0.00%+88,552+47.9%Added
XTX Topco Ltd241,230$834.7K0.03%+161,317+201.9%Added
Susquehanna Portfolio Strategies, LLC238,814$826.3K0.02%+238,814New
Swiss National Bank227,000$785.4K0.00%00.0%Unchanged
Boothbay Fund Management, LLC222,987$771.5K0.02%−3,750−1.7%Reduced
Rhumbline Advisers221,853$767.6K0.00%+47,728+27.4%Added
Manufacturers Life Insurance Company, The212,126$734.0K0.00%+6,547+3.2%Added
Raymond James Financial Inc190,488$659.1K0.00%+5,955+3.2%Added
Congress Wealth Management LLC186,063$643.8K0.01%00.0%Unchanged
Rafferty Asset Management, LLC181,957$629.6K0.00%−23,111−11.3%Reduced
Ieq Capital, LLC179,324$620.5K0.00%+122,990+218.3%Added
UBS Group AG173,090$598.9K0.00%−102,468−37.2%Reduced
ExodusPoint Capital Management, LP170,196$589.0K0.01%+170,196New
Raiffeisen Bank International AG180,000$586.8K0.01%00.0%Unchanged
Thrivent Financial for Lutherans166,668$576.0K0.00%00.0%Unchanged
FMR LLC158,179$547.3K0.00%+115,164+267.7%Added
Congress Asset Management Co156,700$542.2K0.00%+498+0.3%Added
DekaBank Deutsche Girozentrale60,000$531.0K0.00%−8,937−13.0%Reduced
HighVista Strategies LLC149,701$518.0K0.19%+149,701New
Alliancebernstein L.P.145,251$502.6K0.00%−23,030−13.7%Reduced
UBS Oconnor LLC127,036$439.5K0.01%−255,864−66.8%Reduced
Citigroup Inc123,393$426.9K0.00%−136,920−52.6%Reduced
Legal & General Group Plc112,316$388.6K0.00%−16,899−13.1%Reduced
Deutsche Bank AG109,787$379.9K0.00%+39,018+55.1%Added
California State Teachers Retirement System106,287$367.8K0.00%00.0%Unchanged
HSBC Holdings PLC104,257$351.8K0.00%−12,151−10.4%Reduced
Skopos Labs, Inc.101,057$349.7K0.05%+95,002+1,569.0%Added
TD Asset Management Inc99,056$342.7K0.00%−57,400−36.7%Reduced
NEOS Investment Management LLC97,150$336.1K0.00%+8,040+9.0%Added
Tema ETFs LLC97,150$336.1K0.09%+8,040+9.0%Added
ICONIQ Capital, LLC94,697$327.7K0.01%00.0%Unchanged
Alps Advisors Inc92,528$320.1K0.00%+92,528New
Squarepoint Ops LLC87,551$302.9K0.00%−27,068−23.6%Reduced
Wells Fargo & Company84,980$294.0K0.00%+9,466+12.5%Added
Mirae Asset Global ETFs Holdings Ltd.82,363$283.5K0.00%−1,706−2.0%Reduced
Gsa Capital Partners LLP80,562$279.0K0.02%+28,083+53.5%Added
MetLife Investment Management75,117$259.9K0.00%+9,845+15.1%Added
Creative Planning72,618$251.3K0.00%+49,501+214.1%Added
Federated Hermes, Inc.71,217$246.4K0.00%−25,096−26.1%Reduced
OP Asset Management Ltd70,542$244.1K0.00%+70,542New
Los Angeles Capital Management LLC68,615$237.4K0.00%+3,275+5.0%Added
Intellectus Partners, LLC61,425$212.5K0.05%00.0%Unchanged
Allspring Global Investments Holdings, LLC60,331$212.4K0.00%−3,275−5.1%Reduced
Sanctuary Advisors, LLC58,654$202.9K0.00%+58,654New
CWM, LLC56,993$197.0K0.00%+36,724+181.2%Added
Bank of Montreal55,174$190.9K0.00%+23,396+73.6%Added