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Regulus Therapeutics Inc.

RGLSDelisted Jun 25, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001505512

Regulus Therapeutics Inc. was delisted on Jun 25, 2025; its insiders filed their last Form 4 on Jun 27, 2025; 75 institutions reported holding it in 13F filings for Q1 2025, worth $107.0M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Regulus Therapeutics Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
38
−3 vs. Q3 2021
Shares held
30.2M
+7.21M (+31.4%) vs. Q3 2021
Total value
$9.54M
−$6.32M (−39.9%) vs. Q3 2021
New holders
7
8 more added
Sold out
10
8 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 38 institutions
Q1 2021: 44 institutionsQ2 2021: 45 institutionsQ3 2021: 42 institutionsQ4 2021: 38 institutionsQ1 2022: 37 institutionsQ2 2022: 28 institutionsQ3 2022: 25 institutionsQ4 2022: 28 institutionsQ1 2023: 27 institutionsQ2 2023: 26 institutionsQ3 2023: 25 institutionsQ4 2023: 26 institutionsQ1 2024: 45 institutionsQ2 2024: 63 institutionsQ3 2024: 70 institutionsQ4 2024: 69 institutionsQ1 2025: 75 institutionsQ2 2025: 1 institutionQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2021: $9.54M
Q1 2021: $42.6MQ2 2021: $18.7MQ3 2021: $15.9MQ4 2021: $9.54MQ1 2022: $18.1MQ2 2022: $12.6MQ3 2022: $13.8MQ4 2022: $11.1MQ1 2023: $6.82MQ2 2023: $15.0MQ3 2023: $15.0MQ4 2023: $14.2MQ1 2024: $147.3MQ2 2024: $109.5MQ3 2024: $89.1MQ4 2024: $84.5MQ1 2025: $107.0MQ2 2025: $760Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding RGLS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20251$760
Q1 202575$107.0M
Q4 202469$84.5M
Q3 202470$89.1M
Q2 202463$109.5M
Q1 202445$147.3M
Q4 202326$14.2M
Q3 202325$15.0M
Q2 202326$15.0M
Q1 202327$6.82M
Q4 202228$11.1M
Q3 202225$13.8M
Q2 202228$12.6M
Q1 202237$18.1M
Q4 202138$9.54M
Q3 202142$15.9M
Q2 202145$18.7M
Q1 202144$42.6M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Regulus Therapeutics Inc.; share changes are against Q3 2021.

Institutions holding RGLS in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Simplex Trading, LLC1,049$00.00%−17,274−94.3%Reduced
FMR LLC3$00.00%00.0%Unchanged
Morgan Stanley6,000$2.00K0.00%−558,462−98.9%Reduced
Wells Fargo & Company6,848$2.00K0.00%−237−3.3%Reduced
Royal Bank of Canada7,063$2.00K0.00%00.0%Unchanged
Community Bank, N.A.6,900$2.00K0.00%00.0%Unchanged
BlackRock Inc.6,927$2.00K0.00%+4,607+198.6%Added
Endurance Wealth Management, Inc.6,750$2.00K0.00%+6,750New
Tower Research Capital LLC (TRC)6,841$2.00K0.00%+6,841New
Blair William & Co10,700$3.00K0.00%00.0%Unchanged
Creative Planning14,200$4.00K0.00%00.0%Unchanged
Dowling & Yahnke LLC12,000$4.00K0.00%00.0%Unchanged
All Terrain Financial Advisors, LLC15,000$5.00K0.00%00.0%Unchanged
McGuire Investment Group, LLC15,000$5.00K0.00%00.0%Unchanged
Renaissance Technologies LLC22,300$7.00K0.00%+22,300New
UBS Group AG23,953$8.00K0.00%+4,079+20.5%Added
Jane Street Group, LLC24,426$8.00K0.00%+24,426New
GYL Financial Synergies, LLC41,000$13.0K0.00%00.0%Unchanged
Lido Advisors, LLC54,500$17.0K0.00%−3,000−5.2%Reduced
Two Sigma Investments, LP55,306$17.0K0.00%+55,306New
Grimes & Company, Inc.61,076$19.0K0.00%−10,595−14.8%Reduced
WealthTrust Axiom LLC68,000$21.0K0.01%+55,000+423.1%Added
Group One Trading, L.P.88,177$28.0K0.00%−900−1.0%Reduced
Northern Trust Corp117,654$37.0K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC119,000$37.0K0.00%+8,000+7.2%Added
Boothbay Fund Management, LLC124,056$39.0K0.00%00.0%Unchanged
Two Sigma Advisers, LP151,300$48.0K0.00%+139,400+1,171.4%Added
State Street Corp176,494$56.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc184,600$58.0K0.00%+146,500+384.5%Added
Geode Capital Management, LLC589,196$185.0K0.00%−81,551−12.2%Reduced
Ikarian Capital, LLC1,228,416$388.0K0.11%00.0%Unchanged
Sarissa Capital Management LP1,851,851$583.0K0.05%00.0%Unchanged
Victory Capital Management Inc2,233,544$704.0K0.00%+6,332+0.3%Added
Asymmetry Capital Management, L.P.2,731,044$860.0K0.46%+1,329,553+94.9%Added
Vanguard Group Inc3,030,213$955.0K0.00%−74,832−2.4%Reduced
Empery Asset Management, LP5,074,251$1.60M3.34%+5,074,251New
DAFNA Capital Management LLC5,555,555$1.75M0.44%+5,555,555New
NEA Management Company, LLC6,451,056$2.06M0.04%00.0%Unchanged
Endurant Capital Management LP0$00.00%−3,547,208−100.0%Sold out
Bank of America Corp0$00.00%−393,307−100.0%Sold out
Acadian Asset Management LLC0$00.00%−246,191−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−164,155−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−64,708−100.0%Sold out
Citadel Advisors LLC0$00.00%−35,357−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−14,000−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−10,610−100.0%Sold out
AdvisorNet Financial, Inc0$00.00%−7,500−100.0%Sold out
Barclays PLC0$00.00%−50−100.0%Sold out
Sonora Investment Management, LLC––––Not filed