Ultragenyx Pharmaceutical Inc.
RARE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001515673
In the last 90 days, Ultragenyx Pharmaceutical Inc. insiders filed 0 open-market purchases and 5 sales; 311 institutions reported holding it in 13F filings for Q2 2026, worth $3.55B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Ultragenyx Pharmaceutical Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 288
- −8 vs. Q3 2025
- Shares held
- 93.9M
- −797.2K (−0.8%) vs. Q3 2025
- Total value
- $2.16B
- −$688.2M (−24.1%) vs. Q3 2025
- New holders
- 57
- 111 more added
- Sold out
- 65
- 91 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RARE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 311 | $3.55B |
| Q1 2026 | 298 | $2.05B |
| Q4 2025 | 288 | $2.16B |
| Q3 2025 | 303 | $2.87B |
| Q2 2025 | 311 | $3.42B |
| Q1 2025 | 301 | $3.25B |
| Q4 2024 | 314 | $3.68B |
| Q3 2024 | 302 | $4.83B |
| Q2 2024 | 275 | $3.63B |
| Q1 2024 | 270 | $3.73B |
| Q4 2023 | 237 | $3.84B |
| Q3 2023 | 221 | $2.52B |
| Q2 2023 | 243 | $3.21B |
| Q1 2023 | 230 | $2.76B |
| Q4 2022 | 228 | $3.15B |
| Q3 2022 | 233 | $2.81B |
| Q2 2022 | 225 | $4.03B |
| Q1 2022 | 240 | $4.87B |
| Q4 2021 | 235 | $5.69B |
| Q3 2021 | 223 | $6.01B |
| Q2 2021 | 242 | $6.24B |
| Q1 2021 | 255 | $7.73B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Ultragenyx Pharmaceutical Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rafferty Asset Management, LLC | 157,061 | $3.61M | 0.01% | +577+0.4% | Added |
| WCM Investment Management, LLC | 163,272 | $3.72M | 0.01% | −124,837−43.3% | Reduced |
| Catalio Capital Management, LP | 162,550 | $3.74M | 0.66% | −128,712−44.2% | Reduced |
| Royal Bank of Canada | 163,227 | $3.75M | 0.00% | −73,062−30.9% | Reduced |
| Trexquant Investment LP | 165,017 | $3.80M | 0.03% | +9,629+6.2% | Added |
| Swiss National Bank | 171,052 | $3.93M | 0.00% | +6,100+3.7% | Added |
| Woodline Partners LP | 171,805 | $3.95M | 0.02% | −101,446−37.1% | Reduced |
| Schroder Investment Management Group | 175,635 | $4.00M | 0.00% | +25,064+16.6% | Added |
| PDT Partners, LLC | 176,813 | $4.07M | 0.26% | +20,120+12.8% | Added |
| Nomura Asset Management International Inc. | 182,808 | $4.21M | 0.01% | +182,808 | New |
| Fisher Asset Management, LLC | 198,696 | $4.57M | 0.00% | +30,612+18.2% | Added |
| Assenagon Asset Management S.A. | 199,720 | $4.59M | 0.01% | −52,949−21.0% | Reduced |
| Moore Capital Management, LP | 200,000 | $4.60M | 0.09% | −70,000−25.9% | Reduced |
| UBS Asset Management Americas Inc | 204,107 | $4.69M | 0.00% | −2,935−1.4% | Reduced |
| Los Angeles Capital Management LLC | 134,467 | $4.73M | 0.02% | −60,515−31.0% | Reduced |
| Emerald Advisers, LLC | 212,358 | $4.88M | 0.15% | −206,208−49.3% | Reduced |
| Blue Owl Capital Holdings LP | 212,638 | $4.89M | 1.51% | −209,800−49.7% | Reduced |
| Algert Global LLC | 219,232 | $5.04M | 0.08% | −102,401−31.8% | Reduced |
| Caption Management, LLC | 219,500 | $5.05M | 0.22% | +54,999+33.4% | Added |
| 683 Capital Management, LLC | 222,395 | $5.12M | 0.43% | +116,395+109.8% | Added |
| Invesco Ltd. | 230,271 | $5.30M | 0.00% | −564,578−71.0% | Reduced |
| Ensign Peak Advisors, Inc | 250,571 | $5.76M | 0.01% | +73,150+41.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 263,869 | $6.07M | 0.02% | +184,947+234.3% | Added |
| Ameriprise Financial Inc | 276,927 | $6.37M | 0.00% | +138,243+99.7% | Added |
| Adage Capital Partners GP, L.L.C. | 280,000 | $6.44M | 0.01% | −150,000−34.9% | Reduced |
| Verition Fund Management LLC | 282,376 | $6.49M | 0.04% | +258,856+1,100.6% | Added |
| Newtyn Management, LLC | 295,915 | $6.81M | 0.72% | +295,915 | New |
| Motley Fool Wealth Management, LLC | 297,486 | $6.84M | 0.53% | −58,054−16.3% | Reduced |
| Bank of New York Mellon Corp | 298,706 | $6.87M | 0.00% | −26,139−8.0% | Reduced |
| Great Point Partners LLC | 300,000 | $6.90M | 2.24% | +300,000 | New |
| Sphera Funds Management Ltd. | 300,623 | $6.91M | 1.44% | −51,935−14.7% | Reduced |
| Franklin Resources Inc | 309,062 | $7.11M | 0.00% | −368,122−54.4% | Reduced |
| Massachusetts Financial Services Co | 310,108 | $7.13M | 0.00% | −191,055−38.1% | Reduced |
| Eversept Partners, LP | 317,182 | $7.30M | 0.41% | +317,182 | New |
| GordonMD Global Investments LP | 329,101 | $7.57M | 5.43% | +329,101 | New |
| Manufacturers Life Insurance Company, The | 331,169 | $7.61M | 0.01% | −13,754−4.0% | Reduced |
| D. E. Shaw & Co., Inc. | 344,763 | $7.93M | 0.01% | +107,123+45.1% | Added |
| Teacher Retirement System of Texas | 348,350 | $8.01M | 0.03% | +327,502+1,570.9% | Added |
| Privium Fund Management B.V. | 357,502 | $8.22M | 1.51% | +67,698+23.4% | Added |
| Barclays PLC | 359,148 | $8.26M | 0.00% | −66,203−15.6% | Reduced |
| Renaissance Technologies LLC | 366,100 | $8.42M | 0.01% | +344,200+1,571.7% | Added |
| Squarepoint Ops LLC | 390,599 | $8.98M | 0.02% | +256,827+192.0% | Added |
| Goldman Sachs Group Inc | 400,358 | $9.21M | 0.00% | −76,580−16.1% | Reduced |
| Legal & General Group Plc | 411,273 | $9.46M | 0.00% | +8,458+2.1% | Added |
| Fred Alger Management, LLC | 411,863 | $9.47M | 0.04% | −36,854−8.2% | Reduced |
| Two Sigma Investments, LP | 424,049 | $9.75M | 0.01% | +97,869+30.0% | Added |
| Palo Alto Investors LP | 461,294 | $10.6M | 1.48% | +91,763+24.8% | Added |
| Jefferies Financial Group Inc. | 477,092 | $11.0M | 0.09% | +477,092 | New |
| Two Sigma Advisers, LP | 481,600 | $11.1M | 0.02% | −36,100−7.0% | Reduced |
| HRT Financial LP | 501,679 | $11.5M | 0.04% | +501,679 | New |
| Balyasny Asset Management LLC | 520,054 | $12.0M | 0.02% | +520,054 | New |
| Northern Trust Corp | 526,686 | $12.1M | 0.00% | +27,454+5.5% | Added |
| Polar Capital Holdings Plc | 556,628 | $12.8M | 0.06% | −27,082−4.6% | Reduced |
| Charles Schwab Investment Management Inc | 598,924 | $13.8M | 0.00% | −1,236−0.2% | Reduced |
| Deutsche Bank AG | 599,473 | $13.8M | 0.00% | −946,628−61.2% | Reduced |
| Voloridge Investment Management, LLC | 643,356 | $14.8M | 0.05% | +160,774+33.3% | Added |
| UBS Group AG | 668,811 | $15.4M | 0.00% | +121,786+22.3% | Added |
| Schonfeld Strategic Advisors LLC | 741,618 | $17.1M | 0.09% | −402,971−35.2% | Reduced |
| Candriam Luxembourg S.C.A. | 799,384 | $18.4M | 0.09% | +44,670+5.9% | Added |
| Nuveen, LLC | 801,473 | $18.4M | 0.00% | +119,329+17.5% | Added |
| Russell Investments Group, Ltd. | 840,820 | $19.3M | 0.02% | +3690.0% | Added |
| Millennium Management LLC | 880,644 | $20.3M | 0.01% | +781,431+787.6% | Added |
| BNP Paribas Arbitrage, SA | 903,050 | $20.8M | 0.01% | +330,031+57.6% | Added |
| Jane Street Group, LLC | 1,021,499 | $23.5M | 0.03% | +667,331+188.4% | Added |
| Pictet Asset Management Holding SA | 1,231,331 | $26.6M | 0.03% | −226,856−15.6% | Reduced |
| Bank of America Corp | 1,213,928 | $27.9M | 0.00% | +558,907+85.3% | Added |
| Norges Bank | 1,261,026 | $29.0M | 0.00% | +1,261,026 | New |
| Rock Springs Capital Management LP | 1,267,241 | $29.1M | 1.50% | +20,900+1.7% | Added |
| AQR Capital Management LLC | 1,360,497 | $31.3M | 0.02% | +614,315+82.3% | Added |
| GW&K Investment Management, LLC | 1,375,407 | $31.6M | 0.27% | +225,238+19.6% | Added |
| Standard Life Aberdeen plc | 1,469,951 | $33.8M | 0.05% | +496,295+51.0% | Added |
| Price T Rowe Associates Inc | 1,554,366 | $35.8M | 0.00% | −755,808−32.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 1,749,268 | $40.2M | 0.16% | −418,461−19.3% | Reduced |
| Morgan Stanley | 1,826,295 | $42.0M | 0.00% | +916,112+100.7% | Added |
| Geode Capital Management, LLC | 1,838,208 | $42.3M | 0.00% | +257,701+16.3% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,899,661 | $43.7M | 0.05% | +354,382+22.9% | Added |
| Frontier Capital Management Co LLC | 1,965,084 | $45.2M | 0.48% | +895,986+83.8% | Added |
| Suvretta Capital Management, LLC | 2,019,000 | $46.4M | 1.16% | 00.0% | Unchanged |
| Citadel Advisors LLC | 2,326,125 | $53.5M | 0.04% | +1,995,172+602.9% | Added |
| Wellington Management Group LLP | 2,461,910 | $56.6M | 0.01% | +516,781+26.6% | Added |
| FMR LLC | 2,666,249 | $61.3M | 0.00% | −4,617,047−63.4% | Reduced |
| Baker Bros. Advisors LP | 2,772,692 | $63.8M | 0.37% | 00.0% | Unchanged |
| RTW Investments, LP | 3,000,139 | $69.0M | 0.69% | −258,127−7.9% | Reduced |
| Sands Capital Management, LLC | 3,485,724 | $80.2M | 0.24% | −284,129−7.5% | Reduced |
| JPMorgan Chase & Co | 3,974,030 | $91.4M | 0.01% | −37,399−0.9% | Reduced |
| State Street Corp | 4,303,046 | $99.0M | 0.00% | +610,559+16.5% | Added |
| BlackRock, Inc. | 6,631,554 | $152.5M | 0.00% | +206,291+3.2% | Added |
| Vanguard Group Inc | 10,263,815 | $236.1M | 0.00% | +131,087+1.3% | Added |
| Frazier Life Sciences Management, L.P. | 0 | $0 | 0.00% | −983,715−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −750,000−100.0% | Sold out |
| Eagle Health Investments LP | 0 | $0 | 0.00% | −697,000−100.0% | Sold out |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −603,397−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −588,700−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −531,996−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −496,060−100.0% | Sold out |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −395,700−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −285,699−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −265,000−100.0% | Sold out |
| Yiheng Capital Management, L.P. | 0 | $0 | 0.00% | −225,758−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −200,717−100.0% | Sold out |