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uniQure N.V.

QURE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001590560

In the last 90 days, uniQure N.V. insiders filed 0 open-market purchases and 1 sale; 254 institutions reported holding it in 13F filings for Q2 2026, worth $3.02B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in uniQure N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+10 vs. Q3 2025
Shares held
62.0M
+6.68M (+12.1%) vs. Q3 2025
Total value
$1.48B
−$1.74B (−54.0%) vs. Q3 2025
New holders
73
73 more added
Sold out
63
61 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QURE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 226 institutions
Q1 2021: 156 institutionsQ2 2021: 156 institutionsQ3 2021: 176 institutionsQ4 2021: 177 institutionsQ1 2022: 175 institutionsQ2 2022: 169 institutionsQ3 2022: 162 institutionsQ4 2022: 178 institutionsQ1 2023: 175 institutionsQ2 2023: 178 institutionsQ3 2023: 160 institutionsQ4 2023: 144 institutionsQ1 2024: 132 institutionsQ2 2024: 117 institutionsQ3 2024: 131 institutionsQ4 2024: 138 institutionsQ1 2025: 141 institutionsQ2 2025: 143 institutionsQ3 2025: 219 institutionsQ4 2025: 226 institutionsQ1 2026: 214 institutionsQ2 2026: 254 institutions
Value heldQ4 2025: $1.48B
Q1 2021: $1.22BQ2 2021: $1.11BQ3 2021: $1.19BQ4 2021: $783.5MQ1 2022: $685.7MQ2 2022: $756.3MQ3 2022: $788.8MQ4 2022: $912.1MQ1 2023: $838.6MQ2 2023: $412.8MQ3 2023: $240.1MQ4 2023: $255.8MQ1 2024: $168.5MQ2 2024: $142.2MQ3 2024: $193.4MQ4 2024: $735.8MQ1 2025: $533.2MQ2 2025: $738.3MQ3 2025: $3.23BQ4 2025: $1.48BQ1 2026: $972.4MQ2 2026: $3.02B
Institutions holding QURE and their total value by quarter
QuarterHoldersValue
Q2 2026254$3.02B
Q1 2026214$972.4M
Q4 2025226$1.48B
Q3 2025219$3.23B
Q2 2025143$738.3M
Q1 2025141$533.2M
Q4 2024138$735.8M
Q3 2024131$193.4M
Q2 2024117$142.2M
Q1 2024132$168.5M
Q4 2023144$255.8M
Q3 2023160$240.1M
Q2 2023178$412.8M
Q1 2023175$838.6M
Q4 2022178$912.1M
Q3 2022162$788.8M
Q2 2022169$756.3M
Q1 2022175$685.7M
Q4 2021177$783.5M
Q3 2021176$1.19B
Q2 2021156$1.11B
Q1 2021156$1.22B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding uniQure N.V.; share changes are against Q3 2025.

Institutions holding QURE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Point72 Asset Management, L.P.24,439$584.8K0.00%−229,643−90.4%Reduced
Monaco Asset Management SAM25,000$598.3K0.18%−14,913−37.4%Reduced
Monimus Capital Management, LP25,878$619.3K0.41%+25,878New
DnB Asset Management AS27,342$654.3K0.00%+15,540+131.7%Added
SummitTX Capital, L.P.27,708$663.1K0.02%+22,010+386.3%Added
Susquehanna Portfolio Strategies, LLC28,708$687.0K0.01%−840−2.8%Reduced
Voya Investment Management LLC28,850$690.4K0.00%−73,274−71.8%Reduced
Pekin Hardy Strauss, Inc.29,300$701.1K0.06%+29,300New
Havemeyer Place LP29,655$709.6K0.14%+29,655New
Boothbay Fund Management, LLC30,448$728.6K0.02%−8,955−22.7%Reduced
Sectoral Asset Management Inc30,585$731.9K0.59%−155−0.5%Reduced
Birchview Capital, LP30,789$736.8K0.43%−47,939−60.9%Reduced
BIT Capital GmbH31,614$756.5K0.03%+31,614New
Legal & General Group Plc31,964$764.9K0.00%−3,657−10.3%Reduced
Diamond Hill Capital Management Inc33,333$797.7K0.00%00.0%Unchanged
MML Investors Services, LLC33,937$812.1K0.00%+33,937New
California State Teachers Retirement System35,947$860.2K0.00%+4,636+14.8%Added
Ci Investments Inc.37,841$905.5K0.00%−9,595−20.2%Reduced
PFM Health Sciences, LP39,499$945.2K0.10%−6,854−14.8%Reduced
Headlands Technologies LLC39,616$948.0K0.08%−17,792−31.0%Reduced
Massar Capital Management, LP40,529$969.9K0.19%+20,529+102.6%Added
Shay Capital LLC41,073$982.9K0.16%+6,076+17.4%Added
Tejara Capital Ltd42,000$1.01M0.42%+42,000New
Bank of New York Mellon Corp43,309$1.04M0.00%+21,098+95.0%Added
Engineers Gate Manager LP43,356$1.04M0.01%+43,356New
StemPoint Capital LP43,485$1.04M0.18%−478,670−91.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.44,250$1.06M0.00%+6,961+18.7%Added
Diadema Partners LP45,000$1.08M0.64%+45,000New
Y-Intercept (Hong Kong) Ltd45,778$1.10M0.02%+23,074+101.6%Added
Stifel Financial Corp45,987$1.10M0.00%−12,289−21.1%Reduced
Winton Group Ltd48,185$1.15M0.04%+7,209+17.6%Added
Affinity Asset Advisors, LLC50,000$1.20M0.09%−250,000−83.3%Reduced
Senvest Management, LLC50,000$1.20M0.04%+50,000New
Schroder Investment Management Group55,015$1.31M0.00%+55,015New
Profund Advisors LLC59,463$1.42M0.04%+42,379+248.1%Added
Eversept Partners, LP62,820$1.50M0.08%−814,553−92.8%Reduced
SG Americas Securities, LLC64,326$1.54M0.00%+53,747+508.1%Added
Hennion & Walsh Asset Management, Inc.67,739$1.62M0.06%+16,126+31.2%Added
Wells Fargo & Company70,236$1.68M0.00%+59,393+547.8%Added
Ameriprise Financial Inc70,796$1.69M0.00%−88,147−55.5%Reduced
Algert Global LLC72,150$1.73M0.03%+49,340+216.3%Added
ExodusPoint Capital Management, LP73,775$1.77M0.02%+73,775New
Tudor Investment Corp Et Al74,036$1.77M0.01%+45,319+157.8%Added
Moore Capital Management, LP75,000$1.79M0.04%+75,000New
Atom Investors LP78,209$1.87M0.15%+30,918+65.4%Added
Walleye Capital LLC78,996$1.89M0.01%−23,913−23.2%Reduced
Swiss National Bank79,000$1.89M0.00%+2,700+3.5%Added
Rhenman & Partners Asset Management AB79,375$1.90M0.18%+79,375New
UBS Asset Management Americas Inc80,249$1.92M0.00%+80,249New
Capital Fund Management S.A.82,978$1.99M0.02%+82,978New
Clearline Capital LP83,681$2.00M0.15%+83,681New
Royal Bank of Canada85,640$2.05M0.00%−125,773−59.5%Reduced
Marex Group plc85,993$2.06M0.02%−866−1.0%Reduced
Deeter Investments LLP89,085$2.13M0.46%+89,085New
Jefferies Financial Group Inc.90,542$2.17M0.02%00.0%Unchanged
Ikarian Capital, LLC91,060$2.18M0.28%+32,450+55.4%Added
Envestnet Asset Management Inc99,593$2.38M0.00%+88,044+762.4%Added
Simplex Trading, LLC110,675$2.65M0.07%+42,680+62.8%Added
Nan Fung Trinity (HK) Ltd115,494$2.76M0.22%+115,494New
Schonfeld Strategic Advisors LLC122,529$2.93M0.01%−65,668−34.9%Reduced
Hudson Bay Capital Management LP125,500$3.00M0.02%+121,182+2,806.4%Added
Silverarc Capital Management, LLC126,047$3.02M0.44%−328,953−72.3%Reduced
D. E. Shaw & Co., Inc.131,956$3.16M0.00%+99,419+305.6%Added
Balyasny Asset Management LLC135,644$3.25M0.01%−197,591−59.3%Reduced
Flax Pond Capital, LLC146,498$3.51M2.61%+146,498New
New York State Common Retirement Fund147,549$3.53M0.00%+147,549New
Alyeska Investment Group, L.P.151,058$3.61M0.01%+111,058+277.6%Added
Rafferty Asset Management, LLC164,937$3.95M0.01%+82,081+99.1%Added
Northern Trust Corp168,820$4.04M0.00%+16,383+10.7%Added
Squarepoint Ops LLC176,000$4.21M0.01%−5,902−3.2%Reduced
Sofinnova Investments, Inc.176,513$4.22M0.18%+39,651+29.0%Added
Caption Management, LLC177,277$4.24M0.19%−281,023−61.3%Reduced
Citigroup Inc184,765$4.42M0.00%+173,190+1,496.2%Added
Eagle Health Investments LP205,247$4.91M1.08%+205,247New
Price T Rowe Associates Inc208,646$4.99M0.00%−704,534−77.2%Reduced
Barclays PLC209,790$5.02M0.00%+94,228+81.5%Added
Voss Capital, LLC210,000$5.03M0.27%+85,000+68.0%Added
BNP Paribas Arbitrage, SA221,343$5.30M0.00%−164,266−42.6%Reduced
Freshford Capital Management, LLC229,613$5.49M2.20%+229,613New
ADAR1 Capital Management, LLC235,155$5.63M0.42%+101,839+76.4%Added
Parkman Healthcare Partners LLC257,382$6.16M0.59%−87,974−25.5%Reduced
Nomura Asset Management International Inc.258,211$6.18M0.01%+258,211New
Catalio Capital Management, LP288,345$6.90M1.22%+5,405+1.9%Added
Boxer Capital Management, LLC290,000$6.94M1.52%−510,000−63.7%Reduced
Jump Financial, LLC306,131$7.33M0.09%+302,305+7,901.3%Added
HRT Financial LP310,050$7.42M0.02%+310,050New
First Turn Management, LLC321,655$7.70M0.88%+321,655New
Bank of America Corp329,525$7.89M0.00%+34,394+11.7%Added
Fred Alger Management, LLC344,878$8.25M0.03%−945,513−73.3%Reduced
Readystate Asset Management LP361,560$8.65M0.38%+361,560New
Charles Schwab Investment Management Inc362,878$8.68M0.00%+5,193+1.5%Added
683 Capital Management, LLC384,950$9.21M0.77%−685,050−64.0%Reduced
Privium Fund Management B.V.416,270$9.96M1.83%+30,270+7.8%Added
Whitefort Capital Management, LP459,000$11.0M3.32%+459,000New
Citadel Advisors LLC469,300$11.2M0.01%+39,590+9.2%Added
UBS Group AG491,454$11.8M0.00%+286,465+139.7%Added
Eventide Asset Management, LLC498,212$11.9M0.19%+498,212New
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.521,677$12.5M1.11%00.0%Unchanged
Assenagon Asset Management S.A.606,923$14.5M0.02%+606,923New
Maverick Capital LtdSuperinvestorMaverick Capital661,820$15.8M0.17%+661,820New