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Q32 Bio Inc.

QTTB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001661998

In the last 90 days, Q32 Bio Inc. insiders filed 0 open-market purchases and 3 sales; 72 institutions reported holding it in 13F filings for Q2 2026, worth $282.6M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Q32 Bio Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
54
+4 vs. Q4 2025
Shares held
9.43M
+1.71M (+22.1%) vs. Q4 2025
Total value
$60.6M
+$35.0M (+136.9%) vs. Q4 2025
New holders
12
14 more added
Sold out
8
9 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting QTTB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 54 institutions
Q1 2021: 109 institutionsQ2 2021: 118 institutionsQ3 2021: 119 institutionsQ4 2021: 121 institutionsQ1 2022: 107 institutionsQ2 2022: 87 institutionsQ3 2022: 83 institutionsQ4 2022: 79 institutionsQ1 2023: 62 institutionsQ2 2023: 59 institutionsQ3 2023: 58 institutionsQ4 2023: 58 institutionsQ1 2024: 39 institutionsQ2 2024: 54 institutionsQ3 2024: 73 institutionsQ4 2024: 92 institutionsQ1 2025: 73 institutionsQ2 2025: 61 institutionsQ3 2025: 53 institutionsQ4 2025: 52 institutionsQ1 2026: 54 institutionsQ2 2026: 72 institutions
Value heldQ1 2026: $60.6M
Q1 2021: $272.7MQ2 2021: $239.9MQ3 2021: $252.1MQ4 2021: $123.0MQ1 2022: $89.7MQ2 2022: $49.9MQ3 2022: $38.7MQ4 2022: $27.3MQ1 2023: $20.0MQ2 2023: $15.9MQ3 2023: $20.8MQ4 2023: $11.4MQ1 2024: $125.9MQ2 2024: $144.2MQ3 2024: $405.8MQ4 2024: $37.8MQ1 2025: $15.5MQ2 2025: $13.4MQ3 2025: $16.6MQ4 2025: $26.7MQ1 2026: $60.6MQ2 2026: $282.6M
Institutions holding QTTB and their total value by quarter
QuarterHoldersValue
Q2 202672$282.6M
Q1 202654$60.6M
Q4 202552$26.7M
Q3 202553$16.6M
Q2 202561$13.4M
Q1 202573$15.5M
Q4 202492$37.8M
Q3 202473$405.8M
Q2 202454$144.2M
Q1 202439$125.9M
Q4 202358$11.4M
Q3 202358$20.8M
Q2 202359$15.9M
Q1 202362$20.0M
Q4 202279$27.3M
Q3 202283$38.7M
Q2 202287$49.9M
Q1 2022107$89.7M
Q4 2021121$123.0M
Q3 2021119$252.1M
Q2 2021118$239.9M
Q1 2021109$272.7M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Q32 Bio Inc.; share changes are against Q4 2025.

Institutions holding QTTB in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC2,252,987$14.5M0.33%00.0%Unchanged
Atlas Venture Life Science Advisors, LLC2,092,106$13.4M1.70%00.0%Unchanged
Opaleye Management Inc.1,256,228$8.06M1.06%+1,042,865+488.8%Added
Carlyle Group Inc.1,102,741$7.08M0.07%00.0%Unchanged
ARCH Venture Management, LLC320,482$2.06M0.30%00.0%Unchanged
Acorn Capital Advisors, LLC315,052$2.02M0.57%−178,373−36.1%Reduced
Vanguard Capital Management LLC306,401$1.97M0.00%+306,401New
Mackenzie Financial Corp246,304$1.58M0.00%+246,304New
Sanofi244,083$1.57M0.47%00.0%Unchanged
Renaissance Technologies LLC206,915$1.33M0.00%+107,315+107.7%Added
Acadian Asset Management LLC172,586$1.11M0.00%+124,213+256.8%Added
Monimus Capital Management, LP134,310$862.3K0.24%+134,310New
Geode Capital Management, LLC118,152$758.7K0.00%+12,039+11.3%Added
Pfizer Inc101,618$736.7K0.31%−176,159−63.4%Reduced
BlackRock, Inc.86,147$553.1K0.00%+26,215+43.7%Added
Jane Street Group, LLC65,599$421.1K0.00%+40,225+158.5%Added
Marshall Wace, LLP52,440$336.7K0.00%+52,440New
Vanguard Fiduciary Trust Co49,995$321.0K0.00%+49,995New
Two Sigma Investments, LP42,346$271.9K0.00%−4,479−9.6%Reduced
State Street Corp41,514$266.5K0.00%+20,277+95.5%Added
Cambridge Investment Research Advisors, Inc.35,025$225.0K0.00%+35,025New
ADAR1 Capital Management, LLC35,000$224.7K0.01%+15,000+75.0%Added
Affinity Asset Advisors, LLC27,777$178.3K0.01%00.0%Unchanged
Northern Trust Corp25,033$160.7K0.00%00.0%Unchanged
Cetera Investment Advisers20,695$132.9K0.00%+20,695New
American Century Companies Inc18,770$120.5K0.00%+18,770New
Citadel Advisors LLC15,481$99.4K0.00%−30,247−66.1%Reduced
Bridgeway Capital Management, LLC12,613$81.0K0.00%+12,613New
Morgan Stanley9,560$61.4K0.00%+4,082+74.5%Added
EverSource Wealth Advisors, LLC4,640$29.8K0.00%00.0%Unchanged
FMR LLC3,400$21.8K0.00%+36+1.1%Added
Royal Bank of Canada2,744$18.0K0.00%+2,509+1,067.7%Added
Federated Hermes, Inc.2,273$14.6K0.00%00.0%Unchanged
Vanguard Global Advisers, LLC1,915$12.3K0.00%+1,915New
Tower Research Capital LLC (TRC)1,871$12.0K0.00%+895+91.7%Added
SRS Capital Advisors, Inc.1,148$7.37K0.00%+37+3.3%Added
Rockefeller Capital Management L.P.577$3.70K0.00%00.0%Unchanged
Jones Financial Companies LLLP500$3.63K0.00%00.0%Unchanged
Russell Investments Group, Ltd.454$2.92K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA303$1.95K0.00%−5−1.6%Reduced
UBS Group AG270$1.73K0.00%−13,336−98.0%Reduced
Nisa Investment Advisors, LLC166$1.07K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.124$7960.00%−8−6.1%Reduced
Northwestern Mutual Wealth Management Co111$7130.00%+81+270.0%Added
SBI Securities Co., Ltd.104$6680.00%−53−33.8%Reduced
Allworth Financial LP98$6300.00%00.0%Unchanged
Wells Fargo & Company84$5390.00%+84New
Federation des caisses Desjardins du Quebec70$4460.00%00.0%Unchanged
CWM, LLC39$2500.00%−15−27.8%Reduced
Group One Trading, L.P.34$2180.00%00.0%Unchanged
Harbour Investments, Inc.11$710.00%00.0%Unchanged
AdvisorNet Financial, Inc2$130.00%00.0%Unchanged
Danske Bank A/S1$60.00%00.0%Unchanged
Kerr Financial Planning Corp600$00.00%+600New
Millennium Management LLC0$00.00%−51,268−100.0%Sold out
Monaco Asset Management SAM0$00.00%−50,919−100.0%Sold out
HRT Financial LP0$00.00%−24,698−100.0%Sold out
XTX Topco Ltd0$00.00%−20,353−100.0%Sold out
Scientech Research LLC0$00.00%−15,510−100.0%Sold out
Bank of America Corp0$00.00%−1,035−100.0%Sold out
JPMorgan Chase & Co0$00.00%−324−100.0%Sold out
Barclays PLC0$00.00%−19−100.0%Sold out
Vanguard Group Inc––––Not filed
Global Retirement Partners, LLC––––Not filed