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Protalix BioTherapeutics, Inc.

PLX
Exchange
NYSE
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001006281

No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Protalix BioTherapeutics, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of PLX: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders77183+7
Shares13.9M70.4K14.9M+1.05M (+7.6%)
Value$30.9M$152.1K$26.8M−$3.93M (−12.8%)

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (12)

Institutions that held Protalix BioTherapeutics, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to PLX in Q4 2025
InstitutionSharesValue% of portfolio
Jane Street Group, LLC289,917$521.9K0.00%
Round Rock Advisors, LLC155,102$279.2K0.04%
Lazard Asset Management LLC71,393$128.5K0.00%
HRT Financial LP64,610$116.0K0.00%
Two Sigma Securities, LLC39,811$71.7K0.01%
Smartleaf Asset Management LLC25,975$45.2K0.00%
State of Alaska, Department of Revenue21,831$39.0K0.00%
Marshall Wace, LLP19,079$34.3K0.00%
SG Americas Securities, LLC17,155$31.0K0.00%
R Squared Ltd14,632$26.3K0.01%
Equitable Holdings, Inc.11,150$20.1K0.00%
GAMMA Investing LLC355$6390.00%

Sold out (5)

Institutions that held Protalix BioTherapeutics, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of PLX in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
State of Wyoming39,018$86.6K
Virtu Financial LLC16,530$37.0K
Simplex Trading, LLC2,942$6.00K
Truvestments Capital LLC2,458$5.46K
Steward Partners Investment Advisory, LLC25$56

Not filed for Q4 2025 yet (1)

Institutions that held Protalix BioTherapeutics, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding PLX in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Wolverine Trading, LLC70,394$152.1K