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Vaxcyte, Inc.

PCVX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001649094

In the last 90 days, Vaxcyte, Inc. insiders filed 0 open-market purchases and 8 sales; 331 institutions reported holding it in 13F filings for Q2 2026, worth $9.71B in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Vaxcyte, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
295
+16 vs. Q3 2025
Shares held
147.6M
+6.43M (+4.6%) vs. Q3 2025
Total value
$6.81B
+$1.73B (+33.9%) vs. Q3 2025
New holders
61
95 more added
Sold out
45
106 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PCVX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 295 institutions
Q1 2021: 74 institutionsQ2 2021: 75 institutionsQ3 2021: 78 institutionsQ4 2021: 87 institutionsQ1 2022: 88 institutionsQ2 2022: 106 institutionsQ3 2022: 126 institutionsQ4 2022: 198 institutionsQ1 2023: 188 institutionsQ2 2023: 197 institutionsQ3 2023: 202 institutionsQ4 2023: 223 institutionsQ1 2024: 251 institutionsQ2 2024: 265 institutionsQ3 2024: 329 institutionsQ4 2024: 323 institutionsQ1 2025: 315 institutionsQ2 2025: 294 institutionsQ3 2025: 285 institutionsQ4 2025: 295 institutionsQ1 2026: 336 institutionsQ2 2026: 331 institutions
Value heldQ4 2025: $6.81B
Q1 2021: $869.2MQ2 2021: $972.7MQ3 2021: $1.10BQ4 2021: $1.06BQ1 2022: $1.20BQ2 2022: $1.12BQ3 2022: $1.36BQ4 2022: $3.91BQ1 2023: $3.15BQ2 2023: $5.00BQ3 2023: $5.17BQ4 2023: $6.47BQ1 2024: $8.13BQ2 2024: $9.26BQ3 2024: $15.6BQ4 2024: $11.5BQ1 2025: $5.88BQ2 2025: $4.80BQ3 2025: $5.09BQ4 2025: $6.81BQ1 2026: $9.44BQ2 2026: $9.71B
Institutions holding PCVX and their total value by quarter
QuarterHoldersValue
Q2 2026331$9.71B
Q1 2026336$9.44B
Q4 2025295$6.81B
Q3 2025285$5.09B
Q2 2025294$4.80B
Q1 2025315$5.88B
Q4 2024323$11.5B
Q3 2024329$15.6B
Q2 2024265$9.26B
Q1 2024251$8.13B
Q4 2023223$6.47B
Q3 2023202$5.17B
Q2 2023197$5.00B
Q1 2023188$3.15B
Q4 2022198$3.91B
Q3 2022126$1.36B
Q2 2022106$1.12B
Q1 202288$1.20B
Q4 202187$1.06B
Q3 202178$1.10B
Q2 202175$972.7M
Q1 202174$869.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Vaxcyte, Inc.; share changes are against Q3 2025.

Institutions holding PCVX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC13,834,514$638.3M0.03%+1,324,581+10.6%Added
Janus Henderson Group PLC13,387,188$617.7M0.28%+282,985+2.2%Added
Vanguard Group Inc12,193,986$562.6M0.01%−126,467−1.0%Reduced
T. Rowe Price Investment Management, Inc.11,296,333$521.2M0.33%+2,981,038+35.9%Added
Ra Capital Management, L.P.10,724,599$494.8M5.07%−1,241,392−10.4%Reduced
BlackRock, Inc.10,246,378$472.8M0.01%+290,400+2.9%Added
Wellington Management Group LLP5,966,310$275.3M0.05%+933,539+18.5%Added
State Street Corp4,980,005$229.8M0.01%+194,116+4.1%Added
Paradigm Biocapital Advisors LP4,068,020$187.7M5.03%+283,265+7.5%Added
Deep Track Capital, LP4,000,000$184.6M4.21%+1,000,000+33.3%Added
D. E. Shaw & Co., Inc.3,631,053$167.5M0.13%−659,737−15.4%Reduced
Westfield Capital Management Co LP3,539,717$163.3M0.68%−192,998−5.2%Reduced
Kynam Capital Management, LP2,922,335$134.8M8.78%−149,253−4.9%Reduced
Geode Capital Management, LLC2,866,305$132.3M0.01%−17,735−0.6%Reduced
Adage Capital Partners GP, L.L.C.1,725,000$79.6M0.12%+1,392,000+418.0%Added
Caligan Partners LP1,704,815$78.7M7.20%+1,704,815New
Polar Capital Holdings Plc1,672,783$77.2M0.35%+1,257,253+302.6%Added
Pivotal bioVenture Partners Investment Advisor LLC1,372,425$63.3M24.48%00.0%Unchanged
Maverick Capital LtdSuperinvestorMaverick Capital1,354,237$62.5M0.67%+64,670+5.0%Added
Charles Schwab Investment Management Inc1,293,830$59.7M0.01%+4230.0%Added
Norges Bank1,228,939$56.7M0.01%+1,228,939New
Eversept Partners, LP1,197,722$55.3M3.10%−224,261−15.8%Reduced
Price T Rowe Associates Inc1,175,339$54.2M0.01%−513,144−30.4%Reduced
UBS Group AG1,093,593$50.5M0.01%+246,020+29.0%Added
JPMorgan Chase & Co1,085,519$50.1M0.00%−479,517−30.6%Reduced
Goldman Sachs Group Inc1,078,120$49.7M0.01%+102,743+10.5%Added
Northern Trust Corp1,034,180$47.7M0.01%−39,166−3.6%Reduced
Standard Life Aberdeen plc979,765$45.2M0.07%+256,972+35.6%Added
Eventide Asset Management, LLC917,115$42.3M0.66%+537,785+141.8%Added
Novo Holdings A/S916,160$42.3M3.28%00.0%Unchanged
Pictet Asset Management Holding SA881,435$40.7M0.04%−148,194−14.4%Reduced
Capital Research Global Investors842,978$38.9M0.01%00.0%Unchanged
Morgan Stanley835,387$38.5M0.00%+50,904+6.5%Added
Saturn V Capital Management LLC798,940$36.9M6.77%+10,499+1.3%Added
Trails Edge Capital Partners, LP737,470$34.0M8.41%+737,470New
Bank of America Corp701,634$32.4M0.00%+66,564+10.5%Added
Jennison Associates LLC677,553$31.3M0.02%−493,346−42.1%Reduced
Logos Global Management LP650,000$30.0M2.00%+25,000+4.0%Added
Soleus Capital Management, L.P.608,958$28.1M1.19%+608,958New
Brown Advisory Inc566,925$26.2M0.04%−110,060−16.3%Reduced
Victory Capital Management Inc549,514$25.4M0.01%+234,622+74.5%Added
Assenagon Asset Management S.A.544,728$25.1M0.04%+324,778+147.7%Added
Ensign Peak Advisors, Inc527,688$24.3M0.04%−1,165−0.2%Reduced
Federated Hermes, Inc.523,489$24.2M0.04%+505,333+2,783.3%Added
Boothbay Fund Management, LLC497,740$23.0M0.60%+369,009+286.7%Added
EcoR1 Capital, LLC450,000$20.8M0.95%+450,000New
Bank of New York Mellon Corp449,363$20.7M0.00%+9,751+2.2%Added
Millennium Management LLC424,294$19.6M0.01%−524,673−55.3%Reduced
Spruce Street Capital LP400,360$18.5M6.10%+400,360New
UBS Asset Management Americas Inc389,010$17.9M0.00%−9,134−2.3%Reduced
Ikarian Capital, LLC378,682$17.5M2.26%+67,000+21.5%Added
TD Asset Management Inc363,734$16.8M0.01%−34,746−8.7%Reduced
American Century Companies Inc357,300$16.5M0.01%+13,273+3.9%Added
Deutsche Bank AG342,894$15.8M0.01%−54,895−13.8%Reduced
Franklin Resources Inc336,143$15.5M0.00%+370.0%Added
Citadel Advisors LLC326,574$15.1M0.01%+120,775+58.7%Added
ADAR1 Capital Management, LLC315,642$14.6M1.09%+102,578+48.1%Added
Nuveen, LLC307,202$14.2M0.00%−177,436−36.6%Reduced
Ameriprise Financial Inc305,194$14.1M0.00%−69,708−18.6%Reduced
Artisan Partners Limited Partnership304,049$14.0M0.02%+304,049New
Barclays PLC296,195$13.7M0.01%−97,719−24.8%Reduced
Elmind Capital, LP291,500$13.4M3.97%+291,500New
Jane Street Group, LLC279,604$12.9M0.02%−64,093−18.6%Reduced
Tang Capital Management LLC275,000$12.7M0.63%−25,000−8.3%Reduced
Woodline Partners LP274,740$12.7M0.05%+27,754+11.2%Added
University of Wisconsin Foundation247,000$11.4M9.58%+247,000New
Alyeska Investment Group, L.P.244,775$11.3M0.03%00.0%Unchanged
Citigroup Inc241,880$11.2M0.01%−71,198−22.7%Reduced
Swiss National Bank230,400$10.6M0.01%+5,300+2.4%Added
Qube Research & Technologies Ltd207,090$9.56M0.01%−346,759−62.6%Reduced
C WorldWide Group Holding A/S195,000$9.00M0.16%00.0%Unchanged
Segall Bryant & Hamill, LLC193,423$8.92M0.12%+8,628+4.7%Added
Dimensional Fund Advisors LP191,786$8.85M0.00%+163,419+576.1%Added
Raymond James Financial Inc185,851$8.45M0.00%−3,442−1.8%Reduced
Point72 Asset Management, L.P.161,614$7.46M0.01%−535,229−76.8%Reduced
Rhumbline Advisers150,919$6.96M0.01%−32,293−17.6%Reduced
Silverarc Capital Management, LLC148,787$6.87M0.99%−165,552−52.7%Reduced
California Public Employees Retirement System144,603$6.67M0.00%−110.0%Reduced
Nan Fung Trinity (HK) Ltd142,930$6.59M0.52%+38,680+37.1%Added
Invesco Ltd.141,220$6.52M0.00%−37,861−21.1%Reduced
Wells Fargo & Company134,075$6.19M0.00%+8,027+6.4%Added
Alliancebernstein L.P.133,882$6.18M0.00%−1,344−1.0%Reduced
Rafferty Asset Management, LLC133,764$6.17M0.02%−15,650−10.5%Reduced
Readystate Asset Management LP131,637$6.07M0.27%+131,637New
Cormorant Asset Management, LP125,000$5.77M0.33%−50,000−28.6%Reduced
Legal & General Group Plc120,301$5.55M0.00%−10,100−7.7%Reduced
New York State Common Retirement Fund116,817$5.39M0.01%−4,970−4.1%Reduced
HighVista Strategies LLC114,049$5.26M1.36%+27,247+31.4%Added
HRT Financial LP113,950$5.26M0.02%−84−0.1%Reduced
Two Sigma Investments, LP111,310$5.14M0.01%+3,723+3.5%Added
California State Teachers Retirement System110,862$5.12M0.01%+1,418+1.3%Added
Manufacturers Life Insurance Company, The108,445$4.97M0.00%−28,425−20.8%Reduced
Creative Planning102,686$4.74M0.00%+22,363+27.8%Added
NEXTBio Capital Management LP95,485$4.41M2.58%+95,485New
Jump Financial, LLC89,822$4.14M0.05%−101,878−53.1%Reduced
Twinbeech Capital LP78,239$3.61M0.26%−149,848−65.7%Reduced
Banque Pictet & Cie SA71,815$3.31M0.03%−3,049−4.1%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH70,124$3.24M0.01%+35,974+105.3%Added
Man Group plc68,913$3.18M0.01%−175,984−71.9%Reduced
State of Wisconsin Investment Board68,285$3.15M0.01%−8,301−10.8%Reduced