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OptimizeRx Corp

OPRX
Exchange
Nasdaq
Industry
Services-Business Services, NEC
SEC CIK
0001448431

No open-market purchases or sales by OptimizeRx Corp insiders were filed in the last 90 days; 112 institutions reported holding it in 13F filings for Q2 2026, worth $64.2M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in OptimizeRx Corp as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
125
+14 vs. Q2 2025
Shares held
13.4M
+893.6K (+7.2%) vs. Q2 2025
Total value
$273.7M
+$105.5M (+62.7%) vs. Q2 2025
New holders
37
29 more added
Sold out
23
37 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 125 institutions
Q1 2021: 121 institutionsQ2 2021: 142 institutionsQ3 2021: 163 institutionsQ4 2021: 180 institutionsQ1 2022: 153 institutionsQ2 2022: 147 institutionsQ3 2022: 128 institutionsQ4 2022: 129 institutionsQ1 2023: 110 institutionsQ2 2023: 102 institutionsQ3 2023: 95 institutionsQ4 2023: 98 institutionsQ1 2024: 97 institutionsQ2 2024: 92 institutionsQ3 2024: 85 institutionsQ4 2024: 87 institutionsQ1 2025: 87 institutionsQ2 2025: 111 institutionsQ3 2025: 125 institutionsQ4 2025: 129 institutionsQ1 2026: 128 institutionsQ2 2026: 112 institutions
Value heldQ3 2025: $273.7M
Q1 2021: $566.9MQ2 2021: $760.9MQ3 2021: $1.19BQ4 2021: $930.5MQ1 2022: $585.1MQ2 2022: $428.1MQ3 2022: $204.5MQ4 2022: $229.8MQ1 2023: $196.3MQ2 2023: $184.1MQ3 2023: $101.8MQ4 2023: $178.8MQ1 2024: $155.4MQ2 2024: $130.8MQ3 2024: $95.5MQ4 2024: $55.3MQ1 2025: $101.6MQ2 2025: $168.2MQ3 2025: $273.7MQ4 2025: $163.9MQ1 2026: $85.8MQ2 2026: $64.2M
Institutions holding OPRX and their total value by quarter
QuarterHoldersValue
Q2 2026112$64.2M
Q1 2026128$85.8M
Q4 2025129$163.9M
Q3 2025125$273.7M
Q2 2025111$168.2M
Q1 202587$101.6M
Q4 202487$55.3M
Q3 202485$95.5M
Q2 202492$130.8M
Q1 202497$155.4M
Q4 202398$178.8M
Q3 202395$101.8M
Q2 2023102$184.1M
Q1 2023110$196.3M
Q4 2022129$229.8M
Q3 2022128$204.5M
Q2 2022147$428.1M
Q1 2022153$585.1M
Q4 2021180$930.5M
Q3 2021163$1.19B
Q2 2021142$760.9M
Q1 2021121$566.9M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding OptimizeRx Corp; share changes are against Q2 2025.

Institutions holding OPRX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Advisory Services Network, LLC2$410.00%+2New
Essential Partners LLC2$410.00%+2New
Parallel Advisors, LLC5$1030.00%+5New
Farther Finance Advisors, LLC10$2050.00%+10New
Sunbelt Securities, Inc.11$2260.00%+11New
True Wealth Design, LLC14$2870.00%00.0%Unchanged
US Bancorp21$4310.00%+21New
EverSource Wealth Advisors, LLC31$6360.00%+2+6.9%Added
Sterling Capital Management LLC38$7790.00%−3−7.3%Reduced
AdvisorNet Financial, Inc100$2.05K0.00%00.0%Unchanged
HighMark Wealth Management LLC100$2.05K0.00%00.0%Unchanged
Optiver Holding B.V.132$2.71K0.00%+132New
Leonteq Securities AG139$2.85K0.00%+139New
MB, Levis & Associates, LLC200$4.10K0.00%+200New
The PNC Financial Services Group, Inc.259$5.31K0.00%−52−16.7%Reduced
MCF Advisors LLC270$5.54K0.00%+270New
SBI Securities Co., Ltd.273$5.60K0.00%−30−9.9%Reduced
Rise Advisors, LLC286$5.86K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.325$6.66K0.00%+325New
Federated Hermes, Inc.352$7.22K0.00%+210+147.9%Added
Compagnie Lombard Odier SCmA410$8.40K0.00%00.0%Unchanged
GAMMA Investing LLC556$11.4K0.00%−82−12.9%Reduced
Amalgamated Bank592$12.0K0.00%00.0%Unchanged
Simplex Trading, LLC694$14.0K0.00%−7,904−91.9%Reduced
CWM, LLC701$14.0K0.00%+41+6.2%Added
Jones Financial Companies LLLP760$14.3K0.00%00.0%Unchanged
Citigroup Inc982$20.1K0.00%−5,466−84.8%Reduced
Tower Research Capital LLC (TRC)991$20.3K0.00%−1,737−63.7%Reduced
Steward Partners Investment Advisory, LLC1,000$20.5K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,258$25.8K0.00%00.0%Unchanged
California State Teachers Retirement System1,274$26.1K0.00%+1+0.1%Added
Legal & General Group Plc1,658$34.0K0.00%−304−15.5%Reduced
Versant Capital Management, Inc1,793$36.8K0.01%00.0%Unchanged
Covestor Ltd1,914$39.0K0.02%−8−0.4%Reduced
Avalon Trust Co2,000$41.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,121$43.5K0.00%00.0%Unchanged
Global Retirement Partners, LLC2,199$45.1K0.00%−551−20.0%Reduced
Advisor Group Holdings, Inc.2,672$52.5K0.00%+1,244+87.1%Added
Royal Bank of Canada2,963$61.0K0.00%+1,670+129.2%Added
BNP Paribas Arbitrage, SA3,926$80.5K0.00%−148−3.6%Reduced
Police & Firemen's Retirement System of New Jersey4,583$94.0K0.00%+1,051+29.8%Added
New York State Common Retirement Fund5,034$103.2K0.00%00.0%Unchanged
MAI Capital Management5,700$116.8K0.00%00.0%Unchanged
FMR LLC5,868$120.3K0.00%+859+17.1%Added
USA Financial Portformulas Corp6,409$131.4K0.02%+6,409New
JPMorgan Chase & Co6,564$134.6K0.00%−1,673−20.3%Reduced
Mirae Asset Global ETFs Holdings Ltd.7,230$148.2K0.00%−2,332−24.4%Reduced
Group One Trading, L.P.9,674$198.3K0.01%−8,328−46.3%Reduced
Connors Investor Services Inc9,819$201.3K0.02%−12,231−55.5%Reduced
Wesbanco Bank Inc10,000$205.0K0.01%+10,000New
Worth Venture Partners, LLC10,750$220.4K0.65%+10,750New
MetLife Investment Management11,379$233.3K0.00%00.0%Unchanged
Deutsche Bank AG11,664$239.1K0.00%+1,950+20.1%Added
AQR Capital Management LLC12,258$251.3K0.00%+12,258New
Panagora Asset Management Inc12,709$260.5K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.12,765$262.0K0.00%+12,765New
Quantinno Capital Management LP14,347$294.1K0.00%+1,852+14.8%Added
Creative Planning16,159$331.3K0.00%+16,159New
Brendel Financial Advisors LLC17,054$349.6K0.18%+17,054New
Hillsdale Investment Management Inc.18,300$375.1K0.01%+18,300New
Integrated Quantitative Investments LLC18,483$378.9K0.11%+18,483New
Qube Research & Technologies Ltd18,583$381.0K0.00%+18,583New
Principal Financial Group Inc18,826$385.9K0.00%+18,826New
Wells Fargo & Company21,327$437.2K0.00%−3,203−13.1%Reduced
State of Wyoming21,833$447.6K0.05%+21,833New
Harbor Capital Advisors, Inc.22,168$454.0K0.04%+22,168New
Sigma Planning Corp22,298$457.1K0.01%+22,298New
Barclays PLC23,124$474.0K0.00%−7,493−24.5%Reduced
American Century Companies Inc24,164$495.4K0.00%+95+0.4%Added
STRS Ohio24,500$502.3K0.00%+24,500New
Virtus ETF Advisers LLC25,187$516.3K0.28%+9,687+62.5%Added
State of Wisconsin Investment Board27,561$565.0K0.00%+27,561New
LPL Financial LLC28,375$581.7K0.00%+1,985+7.5%Added
Franklin Resources Inc28,630$586.9K0.00%+28,630New
Rhumbline Advisers32,414$664.5K0.00%−3,668−10.2%Reduced
UBS Group AG34,086$698.8K0.00%−68,565−66.8%Reduced
Marshall Wace, LLP35,407$725.8K0.00%−76,564−68.4%Reduced
Perkins Capital Management Inc37,596$770.7K0.68%−1,500−3.8%Reduced
Alliancebernstein L.P.39,850$816.9K0.00%00.0%Unchanged
Nuveen, LLC44,123$904.5K0.00%−36,850−45.5%Reduced
Boothbay Fund Management, LLC47,986$983.7K0.03%+47,986New
Los Angeles Capital Management LLC48,490$994.0K0.00%+22,667+87.8%Added
P.A.W. Capital Corp50,000$1.02M1.86%00.0%Unchanged
Bridgeway Capital Management, LLC59,029$1.21M0.03%−40,000−40.4%Reduced
Schonfeld Strategic Advisors LLC61,648$1.26M0.01%−181,995−74.7%Reduced
Two Sigma Investments, LP63,704$1.31M0.00%−39,041−38.0%Reduced
Janus Henderson Group PLC65,619$1.35M0.00%+8,317+14.5%Added
Ameriprise Financial Inc69,406$1.42M0.00%−474−0.7%Reduced
Granahan Investment Management Inc71,046$1.46M0.06%+71,046New
Charles Schwab Investment Management Inc75,127$1.54M0.00%+23,615+45.8%Added
Calamos Advisors LLC77,002$1.58M0.01%+30,829+66.8%Added
EAM Investors, LLC77,087$1.58M0.18%+13,491+21.2%Added
Avenir Corp77,260$1.58M0.16%00.0%Unchanged
Bank of America Corp84,760$1.74M0.00%+50,518+147.5%Added
Raymond James Financial Inc84,772$1.74M0.00%+217+0.3%Added
Prudential Financial Inc86,485$1.77M0.00%+86,485New
Bank of New York Mellon Corp87,957$1.80M0.00%−1,820−2.0%Reduced
Tang Capital Management LLC100,000$2.05M0.08%00.0%Unchanged
Renaissance Technologies LLC107,900$2.21M0.00%+30,193+38.9%Added
Citadel Advisors LLC108,791$2.23M0.00%−73,555−40.3%Reduced