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OptimizeRx Corp

OPRX
Exchange
Nasdaq
Industry
Services-Business Services, NEC
SEC CIK
0001448431

No open-market purchases or sales by OptimizeRx Corp insiders were filed in the last 90 days; 112 institutions reported holding it in 13F filings for Q2 2026, worth $64.2M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in OptimizeRx Corp as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
128
0 vs. Q4 2025
Shares held
13.6M
+1.42M (+11.6%) vs. Q4 2025
Total value
$85.8M
−$64.2M (−42.8%) vs. Q4 2025
New holders
29
49 more added
Sold out
29
28 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 128 institutions
Q1 2021: 121 institutionsQ2 2021: 142 institutionsQ3 2021: 163 institutionsQ4 2021: 180 institutionsQ1 2022: 153 institutionsQ2 2022: 147 institutionsQ3 2022: 128 institutionsQ4 2022: 129 institutionsQ1 2023: 110 institutionsQ2 2023: 102 institutionsQ3 2023: 95 institutionsQ4 2023: 98 institutionsQ1 2024: 97 institutionsQ2 2024: 92 institutionsQ3 2024: 85 institutionsQ4 2024: 87 institutionsQ1 2025: 87 institutionsQ2 2025: 111 institutionsQ3 2025: 125 institutionsQ4 2025: 129 institutionsQ1 2026: 128 institutionsQ2 2026: 112 institutions
Value heldQ1 2026: $85.8M
Q1 2021: $566.9MQ2 2021: $760.9MQ3 2021: $1.19BQ4 2021: $930.5MQ1 2022: $585.1MQ2 2022: $428.1MQ3 2022: $204.5MQ4 2022: $229.8MQ1 2023: $196.3MQ2 2023: $184.1MQ3 2023: $101.8MQ4 2023: $178.8MQ1 2024: $155.4MQ2 2024: $130.8MQ3 2024: $95.5MQ4 2024: $55.3MQ1 2025: $101.6MQ2 2025: $168.2MQ3 2025: $273.7MQ4 2025: $163.9MQ1 2026: $85.8MQ2 2026: $64.2M
Institutions holding OPRX and their total value by quarter
QuarterHoldersValue
Q2 2026112$64.2M
Q1 2026128$85.8M
Q4 2025129$163.9M
Q3 2025125$273.7M
Q2 2025111$168.2M
Q1 202587$101.6M
Q4 202487$55.3M
Q3 202485$95.5M
Q2 202492$130.8M
Q1 202497$155.4M
Q4 202398$178.8M
Q3 202395$101.8M
Q2 2023102$184.1M
Q1 2023110$196.3M
Q4 2022129$229.8M
Q3 2022128$204.5M
Q2 2022147$428.1M
Q1 2022153$585.1M
Q4 2021180$930.5M
Q3 2021163$1.19B
Q2 2021142$760.9M
Q1 2021121$566.9M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding OptimizeRx Corp; share changes are against Q4 2025.

Institutions holding OPRX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Whetstone Capital Advisors, LLC1,508,303$9.47M3.56%00.0%Unchanged
BlackRock, Inc.1,163,501$7.31M0.00%−31,210−2.6%Reduced
Royce & Associates LP888,030$5.58M0.06%+206,000+30.2%Added
Parkman Healthcare Partners LLC729,369$4.58M0.47%+190,720+35.4%Added
Vanguard Capital Management LLC685,449$4.30M0.00%+685,449New
Kennedy Capital Management, Inc.656,258$4.12M0.09%−17,662−2.6%Reduced
Blair William & Co614,992$3.86M0.01%+32,407+5.6%Added
Rice Hall James & Associates, LLC601,921$3.78M0.21%+11,247+1.9%Added
Dimensional Fund Advisors LP563,570$3.54M0.00%+102,661+22.3%Added
State Street Corp477,780$3.00M0.00%+249+0.1%Added
Geode Capital Management, LLC392,129$2.46M0.00%−4,339−1.1%Reduced
Goldman Sachs Group Inc358,443$2.25M0.00%+231,429+182.2%Added
Vanguard Portfolio Management LLC331,037$2.08M0.00%+331,037New
AWM Investment Company, Inc.230,421$1.45M0.16%00.0%Unchanged
Invenomic Capital Management LP229,370$1.44M0.07%+229,370New
Bullseye Asset Management LLC226,527$1.42M0.82%+20,000+9.7%Added
Renaissance Technologies LLC216,856$1.36M0.00%+187,278+633.2%Added
AQR Capital Management LLC214,954$1.35M0.00%+200,440+1,381.0%Added
Segall Bryant & Hamill, LLC188,704$1.19M0.02%+188,704New
Squarepoint Ops LLC177,571$1.12M0.00%−29,390−14.2%Reduced
Northern Trust Corp155,388$975.8K0.00%−1,539−1.0%Reduced
D. E. Shaw & Co., Inc.142,923$897.6K0.00%+30,056+26.6%Added
Trexquant Investment LP136,874$859.6K0.01%+136,874New
LPL Financial LLC129,608$813.9K0.00%+102,910+385.5%Added
Russell Investments Group, Ltd.125,493$788.1K0.00%−163,567−56.6%Reduced
Qube Research & Technologies Ltd120,943$759.5K0.00%+61,782+104.4%Added
Vanguard Fiduciary Trust Co111,129$697.9K0.00%+111,129New
Bank of New York Mellon Corp102,374$642.9K0.00%−11,884−10.4%Reduced
SEI Investments Co98,633$619.4K0.00%+44,844+83.4%Added
P.A.W. Capital Corp90,000$565.2K0.45%+35,000+63.6%Added
Credit Agricole S A89,200$560.2K0.00%00.0%Unchanged
Vanguard Global Advisers, LLC85,400$536.3K0.00%+85,400New
Raymond James Financial Inc83,163$522.3K0.00%+749+0.9%Added
Charles Schwab Investment Management Inc82,072$515.4K0.00%+754+0.9%Added
UBS Group AG79,261$497.8K0.00%+44,301+126.7%Added
Alliancebernstein L.P.39,850$488.6K0.00%00.0%Unchanged
Avenir Corp77,260$485.2K0.06%00.0%Unchanged
Morgan Stanley76,368$479.6K0.00%−88,224−53.6%Reduced
Schonfeld Strategic Advisors LLC74,761$469.5K0.00%−23,409−23.8%Reduced
FMR LLC69,448$436.1K0.00%+63,857+1,142.1%Added
State of Wisconsin Investment Board68,494$430.1K0.00%+15,400+29.0%Added
Principal Financial Group Inc63,790$400.6K0.00%+36,259+131.7%Added
Ancora Advisors, LLC55,637$349.4K0.01%+55,637New
GWN Securities Inc.54,850$344.5K0.07%+32,492+145.3%Added
Bridgeway Capital Management, LLC54,029$339.3K0.01%−15,000−21.7%Reduced
Manatuck Hill Partners, LLC50,000$314.0K0.10%−372,107−88.2%Reduced
Quantinno Capital Management LP49,022$307.9K0.00%+31,518+180.1%Added
Bank of America Corp43,819$275.2K0.00%+1,243+2.9%Added
Prudential Financial Inc42,705$268.2K0.00%+11,210+35.6%Added
Integrated Quantitative Investments LLC40,723$255.7K0.05%+40,723New
Oxford Asset Management LLP39,024$245.1K0.10%+39,024New
Nuveen, LLC38,998$244.9K0.00%+212+0.5%Added
Man Group plc38,941$244.5K0.00%+38,941New
State of Wyoming35,251$221.4K0.03%+24,716+234.6%Added
Campbell & CO Investment Adviser LLC32,860$206.4K0.01%+19,952+154.6%Added
Marshall Wace, LLP31,286$196.5K0.00%+11,461+57.8%Added
Cetera Investment Advisers27,544$173.0K0.00%+27,544New
Centiva Capital, LP26,573$166.9K0.01%+26,573New
Millennium Management LLC25,315$159.0K0.00%−18,354−42.0%Reduced
STRS Ohio24,500$153.9K0.00%00.0%Unchanged
Franklin Resources Inc24,166$151.8K0.00%+7,882+48.4%Added
Hillsdale Investment Management Inc.20,300$127.5K0.00%00.0%Unchanged
Rhumbline Advisers20,198$126.8K0.00%−7,253−26.4%Reduced
Canada Pension Plan Investment Board19,300$121.2K0.00%+5,400+38.8%Added
XTX Topco Ltd18,423$115.7K0.00%+18,423New
Wells Fargo & Company18,276$114.8K0.00%−10,627−36.8%Reduced
Engineers Gate Manager LP16,474$103.5K0.00%−2,160−11.6%Reduced
Perkins Capital Management Inc15,908$99.9K0.09%−1,500−8.6%Reduced
Los Angeles Capital Management LLC15,866$99.6K0.00%−28,711−64.4%Reduced
Integrated Wealth Concepts LLC14,061$88.3K0.00%+14,061New
HSBC Holdings PLC13,286$84.8K0.00%+13,286New
Mercer Global Advisors Inc12,551$78.8K0.00%+12,551New
Deutsche Bank AG12,397$77.9K0.00%00.0%Unchanged
Virtu Financial LLC11,827$74.0K0.00%+11,827New
Susquehanna International Group, LLP11,373$71.4K0.00%−18,368−61.8%Reduced
Aaron Wealth Advisors10,588$66.5K0.00%+10,588New
McAdam, LLC10,439$65.6K0.00%+10,439New
State of Alaska, Department of Revenue10,067$63.0K0.00%+5,000+98.7%Added
Acadian Asset Management LLC8,478$52.0K0.00%+8,478New
JPMorgan Chase & Co7,365$47.6K0.00%−808−9.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.7,526$47.3K0.00%+170+2.3%Added
CWM, LLC6,562$41.2K0.00%+5,879+860.8%Added
MAI Capital Management6,386$40.1K0.00%+686+12.0%Added
New York State Common Retirement Fund5,034$31.6K0.00%00.0%Unchanged
Barclays PLC4,590$28.8K0.00%−22,851−83.3%Reduced
Police & Firemen's Retirement System of New Jersey4,583$28.8K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA4,243$26.6K0.00%−14−0.3%Reduced
Versant Capital Management, Inc2,041$12.8K0.00%+248+13.8%Added
Avalon Trust Co2,000$12.6K0.00%00.0%Unchanged
Covestor Ltd1,914$12.0K0.01%00.0%Unchanged
Tower Research Capital LLC (TRC)1,829$11.5K0.00%−318−14.8%Reduced
Bard Associates Inc1,480$9.29K0.00%00.0%Unchanged
Legal & General Group Plc1,350$8.48K0.00%−230−14.6%Reduced
Advisor Group Holdings, Inc.1,305$8.19K0.00%+78+6.4%Added
Group One Trading, L.P.1,284$8.06K0.00%−6,767−84.1%Reduced
Ameritas Investment Partners, Inc.1,258$7.90K0.00%00.0%Unchanged
GAMMA Investing LLC1,023$6.42K0.00%+458+81.1%Added
Steward Partners Investment Advisory, LLC1,000$6.28K0.00%00.0%Unchanged
UBS Asset Management Americas Inc940$5.90K0.00%+301+47.1%Added
California State Teachers Retirement System855$5.37K0.00%−117−12.0%Reduced