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Omeros Corp

OMER
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001285819

In the last 90 days, Omeros Corp insiders filed 0 open-market purchases and 6 sales; 171 institutions reported holding it in 13F filings for Q2 2026, worth $343.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Omeros Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+20 vs. Q3 2025
Shares held
33.2M
+422.9K (+1.3%) vs. Q3 2025
Total value
$570.3M
+$435.7M (+323.9%) vs. Q3 2025
New holders
33
61 more added
Sold out
13
35 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OMER on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 151 institutions
Q1 2021: 152 institutionsQ2 2021: 152 institutionsQ3 2021: 142 institutionsQ4 2021: 139 institutionsQ1 2022: 129 institutionsQ2 2022: 102 institutionsQ3 2022: 94 institutionsQ4 2022: 98 institutionsQ1 2023: 91 institutionsQ2 2023: 103 institutionsQ3 2023: 100 institutionsQ4 2023: 97 institutionsQ1 2024: 99 institutionsQ2 2024: 104 institutionsQ3 2024: 108 institutionsQ4 2024: 128 institutionsQ1 2025: 137 institutionsQ2 2025: 128 institutionsQ3 2025: 133 institutionsQ4 2025: 151 institutionsQ1 2026: 162 institutionsQ2 2026: 171 institutions
Value heldQ4 2025: $570.3M
Q1 2021: $618.6MQ2 2021: $478.4MQ3 2021: $417.7MQ4 2021: $202.2MQ1 2022: $173.2MQ2 2022: $66.0MQ3 2022: $64.7MQ4 2022: $44.4MQ1 2023: $94.9MQ2 2023: $142.8MQ3 2023: $78.9MQ4 2023: $81.7MQ1 2024: $87.8MQ2 2024: $101.4MQ3 2024: $99.3MQ4 2024: $262.3MQ1 2025: $226.7MQ2 2025: $87.3MQ3 2025: $134.7MQ4 2025: $570.3MQ1 2026: $326.2MQ2 2026: $343.0M
Institutions holding OMER and their total value by quarter
QuarterHoldersValue
Q2 2026171$343.0M
Q1 2026162$326.2M
Q4 2025151$570.3M
Q3 2025133$134.7M
Q2 2025128$87.3M
Q1 2025137$226.7M
Q4 2024128$262.3M
Q3 2024108$99.3M
Q2 2024104$101.4M
Q1 202499$87.8M
Q4 202397$81.7M
Q3 2023100$78.9M
Q2 2023103$142.8M
Q1 202391$94.9M
Q4 202298$44.4M
Q3 202294$64.7M
Q2 2022102$66.0M
Q1 2022129$173.2M
Q4 2021139$202.2M
Q3 2021142$417.7M
Q2 2021152$478.4M
Q1 2021152$618.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Omeros Corp; share changes are against Q3 2025.

Institutions holding OMER in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.5,062,438$86.9M0.00%+610,282+13.7%Added
Vanguard Group Inc4,013,315$68.9M0.00%+666,357+19.9%Added
Ingalls & Snyder LLC3,448,699$59.2M2.18%−657,899−16.0%Reduced
UBS Group AG2,222,982$38.2M0.01%+1,513,893+213.5%Added
Stifel Financial Corp1,809,766$31.1M0.03%−2,509−0.1%Reduced
Geode Capital Management, LLC1,631,350$28.0M0.00%+95,979+6.3%Added
State Street Corp1,573,526$27.0M0.00%+333,798+26.9%Added
Kotler Kevin905,635$15.6M11.49%+905,635New
D. E. Shaw & Co., Inc.754,999$13.0M0.01%−250,236−24.9%Reduced
Susquehanna International Group, LLP741,895$12.7M0.02%+631,316+570.9%Added
CI Private Wealth, LLC688,025$11.8M0.02%+79,263+13.0%Added
Nomura Holdings Inc655,021$11.2M0.03%+611,340+1,399.6%Added
Bank of Montreal601,643$10.3M0.00%+38,548+6.8%Added
Charles Schwab Investment Management Inc593,222$10.2M0.00%+39,755+7.2%Added
Northern Trust Corp526,732$9.05M0.00%−8,963−1.7%Reduced
Two Sigma Investments, LP524,757$9.01M0.01%−408,557−43.8%Reduced
Royal Bank of Canada498,399$8.56M0.00%−45,277−8.3%Reduced
Jane Street Group, LLC463,622$7.96M0.01%+182,535+64.9%Added
Millennium Management LLC441,811$7.59M0.01%+39,997+10.0%Added
Morgan Stanley386,152$6.63M0.00%−1,603,582−80.6%Reduced
Badgley Phelps Wealth Managers, LLC263,556$4.53M0.08%00.0%Unchanged
Citadel Advisors LLC240,352$4.13M0.00%−152,876−38.9%Reduced
Jump Financial, LLC228,000$3.92M0.05%+228,000New
Goldman Sachs Group Inc227,294$3.90M0.00%−108,793−32.4%Reduced
EAM Investors, LLC207,480$3.56M0.40%+207,480New
Wellington Management Group LLP202,617$3.48M0.00%+8,170+4.2%Added
Itau Unibanco Holding S.A.180,000$3.05M0.08%+180,000New
Bank of New York Mellon Corp165,782$2.85M0.00%+3,437+2.1%Added
Wells Fargo & Company165,280$2.84M0.00%+31,176+23.2%Added
Invesco Ltd.154,782$2.66M0.00%+32,707+26.8%Added
Nuveen, LLC153,187$2.63M0.00%+65,569+74.8%Added
Clutterbuck Capital Management LLC150,000$2.58M2.20%+150,000New
Group One Trading, L.P.133,269$2.29M0.07%+34,972+35.6%Added
Simplex Trading, LLC123,979$2.13M0.06%+101,759+458.0%Added
Barclays PLC120,490$2.07M0.00%−11,458−8.7%Reduced
Ameriprise Financial Inc117,004$2.01M0.00%+468+0.4%Added
Bank of America Corp114,808$1.97M0.00%−160,610−58.3%Reduced
Walleye Capital LLC109,956$1.89M0.01%+95,033+636.8%Added
HighTower Advisors, LLC104,059$1.79M0.00%+8,875+9.3%Added
Rhumbline Advisers100,105$1.72M0.00%−5,768−5.4%Reduced
Dimensional Fund Advisors LP96,948$1.67M0.00%+96,948New
Price T Rowe Associates Inc95,745$1.64M0.00%+6,217+6.9%Added
Susquehanna Portfolio Strategies, LLC92,759$1.59M0.02%−78,329−45.8%Reduced
Quest Partners LLC82,597$1.42M0.08%+82,596+8,259,600.0%Added
Cambridge Investment Research Advisors, Inc.81,643$1.40M0.00%+63,424+348.1%Added
MML Investors Services, LLC77,875$1.34M0.00%+18,700+31.6%Added
Two Sigma Advisers, LP76,100$1.31M0.00%−502,100−86.8%Reduced
Alliancebernstein L.P.73,490$1.26M0.00%+5,900+8.7%Added
Walleye Trading LLC69,653$1.20M0.02%+55,980+409.4%Added
Polar Asset Management Partners Inc.68,800$1.18M0.02%−1,429,786−95.4%Reduced
Brevan Howard Capital Management LP64,957$1.12M0.02%−64,436−49.8%Reduced
American Financial Group Inc64,113$1.10M0.40%00.0%Unchanged
Verition Fund Management LLC63,493$1.09M0.01%+63,493New
Ancora Advisors, LLC59,250$1.02M0.02%+56,250+1,875.0%Added
Bridgeway Capital Management, LLC56,715$974.1K0.02%00.0%Unchanged
Coldstream Capital Management Inc53,605$920.7K0.01%+27,775+107.5%Added
Mindset Wealth Management, LLC52,000$893.1K0.23%−8,000−13.3%Reduced
Deutsche Bank AG48,694$836.6K0.00%+7,891+19.3%Added
Cypress Capital Group42,000$721.4K0.08%00.0%Unchanged
Comerica Bank38,000$652.6K0.00%+3,000+8.6%Added
JPMorgan Chase & Co37,191$638.8K0.00%−378,962−91.1%Reduced
MetLife Investment Management36,200$621.7K0.00%+15,696+76.6%Added
Newbridge Financial Services Group, Inc.34,310$589.3K0.09%−100,200−74.5%Reduced
SEI Investments Co31,766$545.6K0.00%+18,652+142.2%Added
Colony Group, LLC31,034$533.0K0.00%+31,034New
Mirae Asset Global ETFs Holdings Ltd.30,585$525.3K0.00%+399+1.3%Added
Cerity Partners LLC30,450$523.0K0.00%+1,750+6.1%Added
Intech Investment Management LLC29,967$514.7K0.00%+4,324+16.9%Added
Axq Capital, LP29,151$500.7K0.11%+29,151New
Citigroup Inc27,489$472.1K0.00%+21,972+398.3%Added
Man Group plc27,099$465.4K0.00%+27,099New
Virtus Investment Advisers, Inc.26,212$450.2K0.12%+26,212New
Quantinno Capital Management LP25,074$430.6K0.00%+6,866+37.7%Added
ADAR1 Capital Management, LLC25,000$429.4K0.03%+25,000New
Wealth Enhancement Advisory Services, LLC31,728$429.3K0.00%+2,631+9.0%Added
Farallon Capital Management, L.L.C.23,000$395.0K0.00%+23,000New
Stordahl Capital Management, Inc.22,860$392.6K0.08%00.0%Unchanged
AQR Capital Management LLC22,838$392.2K0.00%+1,532+7.2%Added
Harbour Investments, Inc.21,835$375.0K0.01%+8,366+62.1%Added
Canada Pension Plan Investment Board21,700$372.7K0.00%+21,700New
New York State Common Retirement Fund20,713$355.7K0.00%+9,300+81.5%Added
Engineers Gate Manager LP20,082$344.9K0.00%+20,082New
Manufacturers Life Insurance Company, The19,850$340.9K0.00%−48−0.2%Reduced
SG Americas Securities, LLC18,825$323.0K0.00%−26,499−58.5%Reduced
FMR LLC18,068$310.3K0.00%+4,878+37.0%Added
AlphaCore Capital LLC17,647$303.1K0.01%+17,647New
Breakwater Investment Management17,048$292.8K0.11%00.0%Unchanged
Creative Planning16,916$290.5K0.00%+16,916New
China Universal Asset Management Co., Ltd.16,553$284.3K0.02%−5,376−24.5%Reduced
Police & Firemen's Retirement System of New Jersey16,360$281.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA16,351$280.8K0.00%−71,766−81.4%Reduced
ProShare Advisors LLC15,171$260.6K0.00%+1,637+12.1%Added
Profund Advisors LLC14,330$246.1K0.01%+14,330New
Apella Capital, LLC14,288$245.4K0.00%00.0%Unchanged
Russell Investments Group, Ltd.14,014$240.7K0.00%+3,319+31.0%Added
Los Angeles Capital Management LLC30,920$232.5K0.00%+30,920New
Graham Capital Management, L.P.13,222$227.1K0.01%−21,237−61.6%Reduced
Avantax Planning Partners, Inc.13,200$226.7K0.01%+3,100+30.7%Added
Schonfeld Strategic Advisors LLC12,667$217.6K0.00%+12,667New
Raymond James Financial Inc12,242$210.3K0.00%+12,242New