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Omeros Corp

OMER
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001285819

In the last 90 days, Omeros Corp insiders filed 0 open-market purchases and 6 sales; 171 institutions reported holding it in 13F filings for Q2 2026, worth $343.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Omeros Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+20 vs. Q3 2025
Shares held
33.2M
+422.9K (+1.3%) vs. Q3 2025
Total value
$570.3M
+$435.7M (+323.9%) vs. Q3 2025
New holders
33
61 more added
Sold out
13
35 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OMER on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 151 institutions
Q1 2021: 152 institutionsQ2 2021: 152 institutionsQ3 2021: 142 institutionsQ4 2021: 139 institutionsQ1 2022: 129 institutionsQ2 2022: 102 institutionsQ3 2022: 94 institutionsQ4 2022: 98 institutionsQ1 2023: 91 institutionsQ2 2023: 103 institutionsQ3 2023: 100 institutionsQ4 2023: 97 institutionsQ1 2024: 99 institutionsQ2 2024: 104 institutionsQ3 2024: 108 institutionsQ4 2024: 128 institutionsQ1 2025: 137 institutionsQ2 2025: 128 institutionsQ3 2025: 133 institutionsQ4 2025: 151 institutionsQ1 2026: 162 institutionsQ2 2026: 171 institutions
Value heldQ4 2025: $570.3M
Q1 2021: $618.6MQ2 2021: $478.4MQ3 2021: $417.7MQ4 2021: $202.2MQ1 2022: $173.2MQ2 2022: $66.0MQ3 2022: $64.7MQ4 2022: $44.4MQ1 2023: $94.9MQ2 2023: $142.8MQ3 2023: $78.9MQ4 2023: $81.7MQ1 2024: $87.8MQ2 2024: $101.4MQ3 2024: $99.3MQ4 2024: $262.3MQ1 2025: $226.7MQ2 2025: $87.3MQ3 2025: $134.7MQ4 2025: $570.3MQ1 2026: $326.2MQ2 2026: $343.0M
Institutions holding OMER and their total value by quarter
QuarterHoldersValue
Q2 2026171$343.0M
Q1 2026162$326.2M
Q4 2025151$570.3M
Q3 2025133$134.7M
Q2 2025128$87.3M
Q1 2025137$226.7M
Q4 2024128$262.3M
Q3 2024108$99.3M
Q2 2024104$101.4M
Q1 202499$87.8M
Q4 202397$81.7M
Q3 2023100$78.9M
Q2 2023103$142.8M
Q1 202391$94.9M
Q4 202298$44.4M
Q3 202294$64.7M
Q2 2022102$66.0M
Q1 2022129$173.2M
Q4 2021139$202.2M
Q3 2021142$417.7M
Q2 2021152$478.4M
Q1 2021152$618.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Omeros Corp; share changes are against Q3 2025.

Institutions holding OMER in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Essential Partners LLC11$1890.00%00.0%Unchanged
IFP Advisors, Inc26$4470.00%00.0%Unchanged
Parkside Financial Bank & Trust40$6870.00%+40New
Allworth Financial LP44$7560.00%−13−22.8%Reduced
Rocky Mountain Advisers, LLC50$8590.00%00.0%Unchanged
Rothschild Investment LLC60$1.03K0.00%+60New
GAMMA Investing LLC107$1.84K0.00%+107New
EverSource Wealth Advisors, LLC115$1.98K0.00%00.0%Unchanged
Larson Financial Group LLC151$2.59K0.00%+1+0.7%Added
Daiwa Securities Group Inc.191$3.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.195$3.35K0.00%+195New
SBI Securities Co., Ltd.208$3.57K0.00%00.0%Unchanged
UBS Asset Management Americas Inc231$3.97K0.00%+231New
Federation des caisses Desjardins du Quebec300$5.15K0.00%00.0%Unchanged
Pandora Wealth, Inc.330$5.67K0.00%00.0%Unchanged
Massmutual Trust Co FSB360$6.18K0.00%+236+190.3%Added
The PNC Financial Services Group, Inc.377$6.47K0.00%−297−44.1%Reduced
Northwestern Mutual Wealth Management Co500$8.59K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)765$13.1K0.00%−235−23.5%Reduced
Nisa Investment Advisors, LLC804$13.8K0.00%−870−52.0%Reduced
Sterling Capital Management LLC901$15.5K0.00%+256+39.7%Added
Capital Analysts, LLC1,000$17.0K0.00%00.0%Unchanged
Fifth Third Bancorp1,000$17.2K0.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC1,000$17.2K0.00%00.0%Unchanged
GWM Advisors LLC1,000$17.2K0.00%+1,000New
CWM, LLC1,232$21.0K0.00%−28−2.2%Reduced
GF Fund Management Co. Ltd.1,392$23.9K0.00%−72−4.9%Reduced
State of Wyoming1,433$24.6K0.00%+1,433New
Truvestments Capital LLC1,682$28.9K0.01%00.0%Unchanged
Strategic Investment Solutions, Inc.1,827$31.4K0.01%+2+0.1%Added
Tower Research Capital LLC (TRC)1,916$32.9K0.00%−1,512−44.1%Reduced
Amalgamated Bank2,069$36.0K0.00%+17+0.8%Added
Mirae Asset Global Investments Co., Ltd.3,445$59.2K0.00%+814+30.9%Added
Optiver Holding B.V.3,747$64.4K0.00%+3,209+596.5%Added
Parallel Advisors, LLC3,909$67.1K0.00%+750+23.7%Added
California State Teachers Retirement System4,055$69.6K0.00%−10.0%Reduced
International Assets Investment Management, LLC5,000$85.9K0.01%−10,550−67.8%Reduced
Ameritas Investment Partners, Inc.5,027$86.3K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.5,255$90.3K0.00%+1,894+56.4%Added
Vontobel Holding Ltd.5,450$93.6K0.00%+5,450New
Legal & General Group Plc6,971$119.7K0.00%−114−1.6%Reduced
Farther Finance Advisors, LLC7,106$122.0K0.00%+1,004+16.5%Added
Quantbot Technologies LP7,220$124.0K0.00%+7,220New
Advisor Group Holdings, Inc.7,547$129.7K0.00%+1,938+34.6%Added
Caitong International Asset Management Co., Ltd9,276$159.3K0.04%+9,276New
Abel Hall, LLC10,240$175.9K0.04%+10,240New
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management10,500$180.3K0.00%−30,000−74.1%Reduced
Sowell Financial Services LLC10,650$182.9K0.01%+200+1.9%Added
National Asset Management, Inc.11,369$195.3K0.01%+609+5.7%Added
Voya Investment Management LLC11,405$195.9K0.00%+216+1.9%Added
Rafferty Asset Management, LLC12,226$210.0K0.00%+12,226New
Raymond James Financial Inc12,242$210.3K0.00%+12,242New
Schonfeld Strategic Advisors LLC12,667$217.6K0.00%+12,667New
Avantax Planning Partners, Inc.13,200$226.7K0.01%+3,100+30.7%Added
Graham Capital Management, L.P.13,222$227.1K0.01%−21,237−61.6%Reduced
Los Angeles Capital Management LLC30,920$232.5K0.00%+30,920New
Russell Investments Group, Ltd.14,014$240.7K0.00%+3,319+31.0%Added
Apella Capital, LLC14,288$245.4K0.00%00.0%Unchanged
Profund Advisors LLC14,330$246.1K0.01%+14,330New
ProShare Advisors LLC15,171$260.6K0.00%+1,637+12.1%Added
BNP Paribas Arbitrage, SA16,351$280.8K0.00%−71,766−81.4%Reduced
Police & Firemen's Retirement System of New Jersey16,360$281.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.16,553$284.3K0.02%−5,376−24.5%Reduced
Creative Planning16,916$290.5K0.00%+16,916New
Breakwater Investment Management17,048$292.8K0.11%00.0%Unchanged
AlphaCore Capital LLC17,647$303.1K0.01%+17,647New
FMR LLC18,068$310.3K0.00%+4,878+37.0%Added
SG Americas Securities, LLC18,825$323.0K0.00%−26,499−58.5%Reduced
Manufacturers Life Insurance Company, The19,850$340.9K0.00%−48−0.2%Reduced
Engineers Gate Manager LP20,082$344.9K0.00%+20,082New
New York State Common Retirement Fund20,713$355.7K0.00%+9,300+81.5%Added
Canada Pension Plan Investment Board21,700$372.7K0.00%+21,700New
Harbour Investments, Inc.21,835$375.0K0.01%+8,366+62.1%Added
AQR Capital Management LLC22,838$392.2K0.00%+1,532+7.2%Added
Stordahl Capital Management, Inc.22,860$392.6K0.08%00.0%Unchanged
Farallon Capital Management, L.L.C.23,000$395.0K0.00%+23,000New
Wealth Enhancement Advisory Services, LLC31,728$429.3K0.00%+2,631+9.0%Added
ADAR1 Capital Management, LLC25,000$429.4K0.03%+25,000New
Quantinno Capital Management LP25,074$430.6K0.00%+6,866+37.7%Added
Virtus Investment Advisers, Inc.26,212$450.2K0.12%+26,212New
Man Group plc27,099$465.4K0.00%+27,099New
Citigroup Inc27,489$472.1K0.00%+21,972+398.3%Added
Axq Capital, LP29,151$500.7K0.11%+29,151New
Intech Investment Management LLC29,967$514.7K0.00%+4,324+16.9%Added
Cerity Partners LLC30,450$523.0K0.00%+1,750+6.1%Added
Mirae Asset Global ETFs Holdings Ltd.30,585$525.3K0.00%+399+1.3%Added
Colony Group, LLC31,034$533.0K0.00%+31,034New
SEI Investments Co31,766$545.6K0.00%+18,652+142.2%Added
Newbridge Financial Services Group, Inc.34,310$589.3K0.09%−100,200−74.5%Reduced
MetLife Investment Management36,200$621.7K0.00%+15,696+76.6%Added
JPMorgan Chase & Co37,191$638.8K0.00%−378,962−91.1%Reduced
Comerica Bank38,000$652.6K0.00%+3,000+8.6%Added
Cypress Capital Group42,000$721.4K0.08%00.0%Unchanged
Deutsche Bank AG48,694$836.6K0.00%+7,891+19.3%Added
Mindset Wealth Management, LLC52,000$893.1K0.23%−8,000−13.3%Reduced
Coldstream Capital Management Inc53,605$920.7K0.01%+27,775+107.5%Added
Bridgeway Capital Management, LLC56,715$974.1K0.02%00.0%Unchanged
Ancora Advisors, LLC59,250$1.02M0.02%+56,250+1,875.0%Added
Verition Fund Management LLC63,493$1.09M0.01%+63,493New
American Financial Group Inc64,113$1.10M0.40%00.0%Unchanged