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Omeros Corp

OMER
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001285819

In the last 90 days, Omeros Corp insiders filed 0 open-market purchases and 6 sales; 171 institutions reported holding it in 13F filings for Q2 2026, worth $343.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Omeros Corp as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+20 vs. Q3 2025
Shares held
33.2M
+422.9K (+1.3%) vs. Q3 2025
Total value
$570.3M
+$435.7M (+323.9%) vs. Q3 2025
New holders
33
61 more added
Sold out
13
35 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OMER on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 151 institutions
Q1 2021: 152 institutionsQ2 2021: 152 institutionsQ3 2021: 142 institutionsQ4 2021: 139 institutionsQ1 2022: 129 institutionsQ2 2022: 102 institutionsQ3 2022: 94 institutionsQ4 2022: 98 institutionsQ1 2023: 91 institutionsQ2 2023: 103 institutionsQ3 2023: 100 institutionsQ4 2023: 97 institutionsQ1 2024: 99 institutionsQ2 2024: 104 institutionsQ3 2024: 108 institutionsQ4 2024: 128 institutionsQ1 2025: 137 institutionsQ2 2025: 128 institutionsQ3 2025: 133 institutionsQ4 2025: 151 institutionsQ1 2026: 162 institutionsQ2 2026: 171 institutions
Value heldQ4 2025: $570.3M
Q1 2021: $618.6MQ2 2021: $478.4MQ3 2021: $417.7MQ4 2021: $202.2MQ1 2022: $173.2MQ2 2022: $66.0MQ3 2022: $64.7MQ4 2022: $44.4MQ1 2023: $94.9MQ2 2023: $142.8MQ3 2023: $78.9MQ4 2023: $81.7MQ1 2024: $87.8MQ2 2024: $101.4MQ3 2024: $99.3MQ4 2024: $262.3MQ1 2025: $226.7MQ2 2025: $87.3MQ3 2025: $134.7MQ4 2025: $570.3MQ1 2026: $326.2MQ2 2026: $343.0M
Institutions holding OMER and their total value by quarter
QuarterHoldersValue
Q2 2026171$343.0M
Q1 2026162$326.2M
Q4 2025151$570.3M
Q3 2025133$134.7M
Q2 2025128$87.3M
Q1 2025137$226.7M
Q4 2024128$262.3M
Q3 2024108$99.3M
Q2 2024104$101.4M
Q1 202499$87.8M
Q4 202397$81.7M
Q3 2023100$78.9M
Q2 2023103$142.8M
Q1 202391$94.9M
Q4 202298$44.4M
Q3 202294$64.7M
Q2 2022102$66.0M
Q1 2022129$173.2M
Q4 2021139$202.2M
Q3 2021142$417.7M
Q2 2021152$478.4M
Q1 2021152$618.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Omeros Corp; share changes are against Q3 2025.

Institutions holding OMER in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rafferty Asset Management, LLC12,226$210.0K0.00%+12,226New
Voya Investment Management LLC11,405$195.9K0.00%+216+1.9%Added
National Asset Management, Inc.11,369$195.3K0.01%+609+5.7%Added
Sowell Financial Services LLC10,650$182.9K0.01%+200+1.9%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management10,500$180.3K0.00%−30,000−74.1%Reduced
Abel Hall, LLC10,240$175.9K0.04%+10,240New
Caitong International Asset Management Co., Ltd9,276$159.3K0.04%+9,276New
Advisor Group Holdings, Inc.7,547$129.7K0.00%+1,938+34.6%Added
Quantbot Technologies LP7,220$124.0K0.00%+7,220New
Farther Finance Advisors, LLC7,106$122.0K0.00%+1,004+16.5%Added
Legal & General Group Plc6,971$119.7K0.00%−114−1.6%Reduced
Vontobel Holding Ltd.5,450$93.6K0.00%+5,450New
SRS Capital Advisors, Inc.5,255$90.3K0.00%+1,894+56.4%Added
Ameritas Investment Partners, Inc.5,027$86.3K0.00%00.0%Unchanged
International Assets Investment Management, LLC5,000$85.9K0.01%−10,550−67.8%Reduced
California State Teachers Retirement System4,055$69.6K0.00%−10.0%Reduced
Parallel Advisors, LLC3,909$67.1K0.00%+750+23.7%Added
Optiver Holding B.V.3,747$64.4K0.00%+3,209+596.5%Added
Mirae Asset Global Investments Co., Ltd.3,445$59.2K0.00%+814+30.9%Added
Amalgamated Bank2,069$36.0K0.00%+17+0.8%Added
Tower Research Capital LLC (TRC)1,916$32.9K0.00%−1,512−44.1%Reduced
Strategic Investment Solutions, Inc.1,827$31.4K0.01%+2+0.1%Added
Truvestments Capital LLC1,682$28.9K0.01%00.0%Unchanged
State of Wyoming1,433$24.6K0.00%+1,433New
GF Fund Management Co. Ltd.1,392$23.9K0.00%−72−4.9%Reduced
CWM, LLC1,232$21.0K0.00%−28−2.2%Reduced
Fifth Third Bancorp1,000$17.2K0.00%00.0%Unchanged
Plante Moran Financial Advisors, LLC1,000$17.2K0.00%00.0%Unchanged
GWM Advisors LLC1,000$17.2K0.00%+1,000New
Capital Analysts, LLC1,000$17.0K0.00%00.0%Unchanged
Sterling Capital Management LLC901$15.5K0.00%+256+39.7%Added
Nisa Investment Advisors, LLC804$13.8K0.00%−870−52.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)765$13.1K0.00%−235−23.5%Reduced
Northwestern Mutual Wealth Management Co500$8.59K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.377$6.47K0.00%−297−44.1%Reduced
Massmutual Trust Co FSB360$6.18K0.00%+236+190.3%Added
Pandora Wealth, Inc.330$5.67K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec300$5.15K0.00%00.0%Unchanged
UBS Asset Management Americas Inc231$3.97K0.00%+231New
SBI Securities Co., Ltd.208$3.57K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.195$3.35K0.00%+195New
Daiwa Securities Group Inc.191$3.00K0.00%00.0%Unchanged
Larson Financial Group LLC151$2.59K0.00%+1+0.7%Added
EverSource Wealth Advisors, LLC115$1.98K0.00%00.0%Unchanged
GAMMA Investing LLC107$1.84K0.00%+107New
Rothschild Investment LLC60$1.03K0.00%+60New
Rocky Mountain Advisers, LLC50$8590.00%00.0%Unchanged
Allworth Financial LP44$7560.00%−13−22.8%Reduced
Parkside Financial Bank & Trust40$6870.00%+40New
IFP Advisors, Inc26$4470.00%00.0%Unchanged
Essential Partners LLC11$1890.00%00.0%Unchanged
Marshall Wace, LLP0$00.00%−464,178−100.0%Sold out
Renaissance Technologies LLC0$00.00%−344,500−100.0%Sold out
Squarepoint Ops LLC0$00.00%−155,496−100.0%Sold out
DeepCurrents Investment Group LLC0$00.00%−120,918−100.0%Sold out
Atom Investors LP0$00.00%−53,266−100.0%Sold out
Skopos Labs, Inc.0$00.00%−49,197−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−33,678−100.0%Sold out
Brighton Jones LLC0$00.00%−31,539−100.0%Sold out
Quadrature Capital Ltd0$00.00%−21,533−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−10,004−100.0%Sold out
MAI Capital Management0$00.00%−1,369−100.0%Sold out
US Bancorp0$00.00%−50−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−26−100.0%Sold out
Wolverine Trading, LLC––––Not filed
SPC Financial, Inc.––––Not filed