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Orchestra BioMed Holdings, Inc.

OBIO
Exchange
Nasdaq
Industry
Surgical & Medical Instruments & Apparatus
SEC CIK
0001814114

In the last 90 days, Orchestra BioMed Holdings, Inc. insiders filed 2 open-market purchases and 3 sales; 77 institutions reported holding it in 13F filings for Q2 2026, worth $119.4M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Orchestra BioMed Holdings, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
56
+3 vs. Q4 2024
Shares held
19.0M
−217.6K (−1.1%) vs. Q4 2024
Total value
$81.3M
+$4.45M (+5.8%) vs. Q4 2024
New holders
7
16 more added
Sold out
4
18 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 56 institutions
Q1 2021: 46 institutionsQ2 2021: 51 institutionsQ3 2021: 48 institutionsQ4 2021: 53 institutionsQ1 2022: 59 institutionsQ2 2022: 62 institutionsQ3 2022: 23 institutionsQ4 2022: 24 institutionsQ1 2023: 22 institutionsQ2 2023: 39 institutionsQ3 2023: 42 institutionsQ4 2023: 39 institutionsQ1 2024: 43 institutionsQ2 2024: 47 institutionsQ3 2024: 48 institutionsQ4 2024: 54 institutionsQ1 2025: 56 institutionsQ2 2025: 59 institutionsQ3 2025: 52 institutionsQ4 2025: 63 institutionsQ1 2026: 65 institutionsQ2 2026: 77 institutions
Value heldQ1 2025: $81.3M
Q1 2021: $130.2MQ2 2021: $124.1MQ3 2021: $120.6MQ4 2021: $129.0MQ1 2022: $139.4MQ2 2022: $142.3MQ3 2022: $56.4MQ4 2022: $56.6MQ1 2023: $193.2MQ2 2023: $75.5MQ3 2023: $114.2MQ4 2023: $121.2MQ1 2024: $70.3MQ2 2024: $115.9MQ3 2024: $97.8MQ4 2024: $77.0MQ1 2025: $81.3MQ2 2025: $47.6MQ3 2025: $56.1MQ4 2025: $90.1MQ1 2026: $98.2MQ2 2026: $119.4M
Institutions holding OBIO and their total value by quarter
QuarterHoldersValue
Q2 202677$119.4M
Q1 202665$98.2M
Q4 202563$90.1M
Q3 202552$56.1M
Q2 202559$47.6M
Q1 202556$81.3M
Q4 202454$77.0M
Q3 202448$97.8M
Q2 202447$115.9M
Q1 202443$70.3M
Q4 202339$121.2M
Q3 202342$114.2M
Q2 202339$75.5M
Q1 202322$193.2M
Q4 202224$56.6M
Q3 202223$56.4M
Q2 202262$142.3M
Q1 202259$139.4M
Q4 202153$129.0M
Q3 202148$120.6M
Q2 202151$124.1M
Q1 202146$130.2M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Orchestra BioMed Holdings, Inc.; share changes are against Q4 2024.

Institutions holding OBIO in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP8,206,162$35.1M0.54%00.0%Unchanged
Perceptive Advisors LLC4,592,556$19.7M0.70%00.0%Unchanged
BlackRock, Inc.1,945,656$8.33M0.00%−33,174−1.7%Reduced
Vanguard Group Inc1,307,766$5.60M0.00%−9,804−0.7%Reduced
Geode Capital Management, LLC595,432$2.55M0.00%+22,991+4.0%Added
State Street Corp473,719$2.03M0.00%+26,007+5.8%Added
Price T Rowe Associates Inc460,120$1.97M0.00%−27,050−5.6%Reduced
Northern Trust Corp238,701$1.02M0.00%+1,940+0.8%Added
Charles Schwab Investment Management Inc216,985$928.7K0.00%−1,670−0.8%Reduced
IFP Advisors, Inc161,921$693.0K0.02%+83,481+106.4%Added
TD Asset Management Inc92,678$396.7K0.00%00.0%Unchanged
HighTower Advisors, LLC61,000$261.1K0.00%−7,500−10.9%Reduced
Lasry Marc60,869$260.5K1.20%00.0%Unchanged
Bank of New York Mellon Corp52,490$224.7K0.00%−315−0.6%Reduced
Holos Integrated Wealth LLC51,595$220.8K0.14%00.0%Unchanged
Goldman Sachs Group Inc48,729$208.6K0.00%−13,408−21.6%Reduced
Manufacturers Life Insurance Company, The41,984$179.7K0.00%+4,975+13.4%Added
Nuveen, LLC41,729$178.6K0.00%+41,729New
Susquehanna International Group, LLP32,988$141.2K0.00%+20,819+171.1%Added
Morgan Stanley32,134$137.5K0.00%−19,497−37.8%Reduced
Rhumbline Advisers31,657$135.5K0.00%+914+3.0%Added
Barclays PLC25,609$109.6K0.00%−12,177−32.2%Reduced
Citadel Advisors LLC20,480$87.7K0.00%+8,201+66.8%Added
Deutsche Bank AG20,219$86.5K0.00%+8,134+67.3%Added
UBS Group AG17,270$73.9K0.00%−6,795−28.2%Reduced
Citigroup Inc17,218$73.7K0.00%−2,029−10.5%Reduced
Intech Investment Management LLC16,002$68.5K0.00%+5,511+52.5%Added
Bank of America Corp15,899$68.0K0.00%−7,881−33.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.15,043$64.4K0.00%+1,747+13.1%Added
Wells Fargo & Company13,453$57.6K0.00%+297+2.3%Added
ABLE Financial Group, LLC13,402$57.4K0.02%00.0%Unchanged
Corebridge Financial, Inc.12,030$51.5K0.00%−178−1.5%Reduced
JPMorgan Chase & Co11,952$51.2K0.00%−37,453−75.8%Reduced
SEI Investments Co10,290$44.0K0.00%00.0%Unchanged
Massar Capital Management, LP10,000$42.8K0.05%+10,000New
Police & Firemen's Retirement System of New Jersey4,671$20.0K0.00%00.0%Unchanged
New York State Common Retirement Fund3,623$15.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,256$9.66K0.00%−67−2.9%Reduced
Legal & General Group Plc2,225$9.52K0.00%00.0%Unchanged
Harbour Investments, Inc.1,988$8.51K0.00%00.0%Unchanged
California State Teachers Retirement System1,893$8.10K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA1,835$7.85K0.00%−2,623−58.8%Reduced
Larson Financial Group LLC1,831$7.84K0.00%+1,831New
Ameritas Investment Partners, Inc.1,396$5.97K0.00%00.0%Unchanged
FMR LLC1,096$4.69K0.00%+89+8.8%Added
Amalgamated Bank847$4.00K0.00%+335+65.4%Added
Nisa Investment Advisors, LLC805$3.44K0.00%+733+1,018.1%Added
Royal Bank of Canada614$3.00K0.00%−3,450−84.9%Reduced
Northwestern Mutual Wealth Management Co447$1.91K0.00%+447New
Sterling Capital Management LLC247$1.06K0.00%−215−46.5%Reduced
Sierra Ocean, LLC119$5090.00%00.0%Unchanged
GAMMA Investing LLC101$4320.00%+101New
True Wealth Design, LLC6$260.00%+6New
EverSource Wealth Advisors, LLC5$210.00%+5New
SBI Securities Co., Ltd.1$40.00%00.0%Unchanged
CWM, LLC48$00.00%+38+380.0%Added
Boxer Capital Management, LLC0$00.00%−238,193−100.0%Sold out
Millennium Management LLC0$00.00%−21,513−100.0%Sold out
SG Americas Securities, LLC0$00.00%−12,785−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−125−100.0%Sold out
Nuveen Asset Management, LLC––––Not filed