Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Mineralys Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 215
- −5 vs. Q4 2025
- Shares held
- 90.3M
- +5.56M (+6.6%) vs. Q4 2025
- Total value
- $2.46B
- −$621.1M (−20.2%) vs. Q4 2025
- New holders
- 33
- 98 more added
- Sold out
- 38
- 52 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sectoral Asset Management Inc | 31,618 | $895.1K | 0.74% | −70.0% | Reduced |
| Victory Capital Management Inc | 33,141 | $897.8K | 0.00% | +260+0.8% | Added |
| Barclays PLC | 33,877 | $917.7K | 0.00% | −189,406−84.8% | Reduced |
| Legal & General Group Plc | 38,473 | $1.04M | 0.00% | −5,465−12.4% | Reduced |
| DAFNA Capital Management LLC | 38,490 | $1.04M | 0.24% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 45,000 | $1.06M | 0.01% | 00.0% | Unchanged |
| Deutsche Bank AG | 40,116 | $1.09M | 0.00% | +2,871+7.7% | Added |
| Profund Advisors LLC | 41,984 | $1.14M | 0.04% | −5,040−10.7% | Reduced |
| Invesco Ltd. | 42,311 | $1.15M | 0.00% | +13,170+45.2% | Added |
| JPMorgan Chase & Co | 51,922 | $1.22M | 0.00% | +5,239+11.2% | Added |
| HighVista Strategies LLC | 46,778 | $1.27M | 0.35% | −77,766−62.4% | Reduced |
| Los Angeles Capital Management LLC | 46,835 | $1.27M | 0.00% | +46,560+16,930.9% | Added |
| Canada Pension Plan Investment Board | 51,400 | $1.39M | 0.00% | +21,800+73.6% | Added |
| Trexquant Investment LP | 57,200 | $1.55M | 0.01% | −55,588−49.3% | Reduced |
| Rhumbline Advisers | 57,444 | $1.56M | 0.00% | +3,160+5.8% | Added |
| Greenland Capital Management LP | 57,500 | $1.56M | 0.31% | −11,500−16.7% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 59,242 | $1.60M | 0.00% | −52,511−47.0% | Reduced |
| Prudential Financial Inc | 59,555 | $1.61M | 0.00% | −29,510−33.1% | Reduced |
| California State Teachers Retirement System | 61,266 | $1.66M | 0.00% | +17,918+41.3% | Added |
| State of Wisconsin Investment Board | 64,138 | $1.74M | 0.00% | +14,197+28.4% | Added |
| Alps Advisors Inc | 64,419 | $1.75M | 0.01% | −568−0.9% | Reduced |
| XTX Topco Ltd | 68,407 | $1.85M | 0.03% | −5,271−7.2% | Reduced |
| Seven Fleet Capital Management LP | 69,571 | $1.88M | 0.59% | +27,546+65.5% | Added |
| Hennion & Walsh Asset Management, Inc. | 70,189 | $1.90M | 0.06% | +827+1.2% | Added |
| Susquehanna Portfolio Strategies, LLC | 78,092 | $2.12M | 0.03% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 79,537 | $2.15M | 0.00% | +3,640+4.8% | Added |
| Ishara Investments LP | 82,000 | $2.22M | 2.24% | +82,000 | New |
| CenterBook Partners LP | 89,330 | $2.42M | 0.13% | +63,330+243.6% | Added |
| Swiss National Bank | 90,100 | $2.44M | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 90,929 | $2.46M | 0.03% | −48,364−34.7% | Reduced |
| J. Goldman & Co LP | 94,101 | $2.55M | 0.12% | +46,813+99.0% | Added |
| Rafferty Asset Management, LLC | 94,358 | $2.56M | 0.01% | −33,559−26.2% | Reduced |
| Verition Fund Management LLC | 95,122 | $2.58M | 0.02% | +11,282+13.5% | Added |
| HRT Financial LP | 95,920 | $2.60M | 0.01% | +58,684+157.6% | Added |
| UBS Group AG | 98,029 | $2.66M | 0.00% | −103,251−51.3% | Reduced |
| Capital Fund Management S.A. | 102,202 | $2.77M | 0.02% | +102,202 | New |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 104,961 | $2.84M | 0.24% | −554,115−84.1% | Reduced |
| Squarepoint Ops LLC | 105,491 | $2.86M | 0.01% | −141,313−57.3% | Reduced |
| Nuveen, LLC | 112,007 | $3.03M | 0.00% | −10,940−8.9% | Reduced |
| Ensign Peak Advisors, Inc | 112,190 | $3.04M | 0.01% | 00.0% | Unchanged |
| Schroder Investment Management Group | 130,592 | $3.07M | 0.00% | 00.0% | Unchanged |
| Swedbank AB | 122,100 | $3.31M | 0.00% | −99,300−44.9% | Reduced |
| Bank of New York Mellon Corp | 129,964 | $3.52M | 0.00% | −1,875−1.4% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 132,099 | $3.58M | 0.07% | +100,740+321.2% | Added |
| Dimensional Fund Advisors LP | 137,433 | $3.72M | 0.00% | −203−0.1% | Reduced |
| Artia Global Partners LP | 137,800 | $3.73M | 0.84% | 00.0% | Unchanged |
| PFM Health Sciences, LP | 142,677 | $3.87M | 0.41% | +95,040+199.5% | Added |
| Mark Asset Management LP | 144,875 | $3.92M | 0.52% | +144,875 | New |
| AQR Capital Management LLC | 149,086 | $4.04M | 0.00% | +86,786+139.3% | Added |
| Burkehill Global Management, LP | 150,000 | $4.06M | 0.20% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 154,686 | $4.19M | 0.25% | +18,455+13.5% | Added |
| Tudor Investment Corp Et Al | 155,740 | $4.22M | 0.02% | +116,694+298.9% | Added |
| Buckley Capital Advisors, LLC | 173,100 | $4.69M | 3.97% | −1,200−0.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 177,585 | $4.81M | 0.04% | +127,764+256.4% | Added |
| Findell Capital Management LLC | 202,000 | $5.47M | 1.61% | +152,000+304.0% | Added |
| Russell Investments Group, Ltd. | 203,504 | $5.51M | 0.01% | +28,143+16.0% | Added |
| Voya Investment Management LLC | 216,089 | $5.85M | 0.01% | +103,417+91.8% | Added |
| Ameriprise Financial Inc | 221,305 | $6.00M | 0.00% | +175,059+378.5% | Added |
| SG Americas Securities, LLC | 225,833 | $6.12M | 0.01% | −4,962−2.1% | Reduced |
| Algert Global LLC | 260,264 | $7.05M | 0.11% | +212,764+447.9% | Added |
| Rhenman & Partners Asset Management AB | 263,071 | $7.13M | 0.88% | +120,500+84.5% | Added |
| Lord, Abbett & Co. LLC | 300,913 | $8.15M | 0.03% | −11,483−3.7% | Reduced |
| Two Sigma Investments, LP | 311,488 | $8.44M | 0.01% | −298,915−49.0% | Reduced |
| TimesSquare Capital Management, LLC | 338,798 | $9.18M | 0.16% | −41,302−10.9% | Reduced |
| Pale Fire Capital SE | 365,626 | $9.90M | 0.87% | +355,272+3,431.3% | Added |
| Vanguard Fiduciary Trust Co | 375,262 | $10.2M | 0.00% | +375,262 | New |
| Parkman Healthcare Partners LLC | 380,137 | $10.3M | 1.07% | −30,112−7.3% | Reduced |
| Renaissance Technologies LLC | 382,800 | $10.4M | 0.02% | +60,700+18.8% | Added |
| Capital World Investors | 398,179 | $10.8M | 0.00% | +398,179 | New |
| Catalio Capital Management, LP | 439,041 | $11.9M | 2.48% | +107,192+32.3% | Added |
| Rock Springs Capital Management LP | 439,751 | $11.9M | 0.70% | +12,155+2.8% | Added |
| Northern Trust Corp | 442,874 | $12.0M | 0.00% | +143,011+47.7% | Added |
| Charles Schwab Investment Management Inc | 443,898 | $12.0M | 0.00% | −17,402−3.8% | Reduced |
| 22NW, LP | 444,325 | $12.0M | 9.47% | +86,000+24.0% | Added |
| Davern Capital Partners, LP | 447,153 | $12.1M | 3.32% | +236,505+112.3% | Added |
| Millennium Management LLC | 525,260 | $14.2M | 0.01% | +446,635+568.1% | Added |
| StemPoint Capital LP | 533,378 | $14.4M | 2.78% | +243,329+83.9% | Added |
| Citadel Advisors LLC | 600,041 | $16.3M | 0.01% | +200,122+50.0% | Added |
| Troluce Capital Advisors LLC | 655,000 | $17.7M | 1.88% | +655,000 | New |
| Vanguard Portfolio Management LLC | 706,658 | $19.1M | 0.00% | +706,658 | New |
| Integral Health Asset Management, LLC | 750,000 | $20.3M | 1.08% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 750,000 | $20.3M | 1.19% | +20,000+2.7% | Added |
| Goldman Sachs Group Inc | 785,043 | $21.3M | 0.00% | −665,890−45.9% | Reduced |
| Candriam Luxembourg S.C.A. | 801,904 | $21.7M | 0.11% | +123,517+18.2% | Added |
| Morgan Stanley | 849,184 | $23.0M | 0.00% | +209,677+32.8% | Added |
| American Century Companies Inc | 884,107 | $24.0M | 0.01% | −23,986−2.6% | Reduced |
| D. E. Shaw & Co., Inc. | 887,192 | $24.0M | 0.02% | −263,478−22.9% | Reduced |
| Nantahala Capital Management, LLC | 895,481 | $24.3M | 1.51% | +782,196+690.5% | Added |
| Qube Research & Technologies Ltd | 914,728 | $24.8M | 0.04% | +418,179+84.2% | Added |
| Boothbay Fund Management, LLC | 1,001,728 | $27.1M | 0.64% | +9,646+1.0% | Added |
| Pictet Asset Management Holding SA | 1,034,438 | $28.0M | 0.03% | +181,555+21.3% | Added |
| Bank of America Corp | 1,100,372 | $29.8M | 0.00% | +113,092+11.5% | Added |
| Armistice Capital, LLC | 1,176,000 | $31.9M | 1.05% | +499,965+74.0% | Added |
| Jennison Associates LLC | 1,266,174 | $34.3M | 0.02% | +7,521+0.6% | Added |
| Geode Capital Management, LLC | 1,301,135 | $35.3M | 0.00% | +43,553+3.5% | Added |
| Alliancebernstein L.P. | 975,961 | $35.4M | 0.01% | +53,445+5.8% | Added |
| Sphera Funds Management Ltd. | 1,339,971 | $36.3M | 6.24% | +890,968+198.4% | Added |
| Price T Rowe Associates Inc | 1,343,313 | $36.4M | 0.00% | +18,193+1.4% | Added |
| Polar Capital Holdings Plc | 1,500,749 | $40.7M | 0.18% | +99,608+7.1% | Added |
| Suvretta Capital Management, LLC | 1,538,662 | $41.7M | 1.13% | 00.0% | Unchanged |