Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 223
- +32 vs. Q3 2025
- Shares held
- 88.4M
- +9.06M (+11.4%) vs. Q3 2025
- Total value
- $3.21B
- +$199.8M (+6.6%) vs. Q3 2025
- New holders
- 52
- 82 more added
- Sold out
- 20
- 72 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital International Investors | 1,163,290 | $42.2M | 0.01% | −1,230,106−51.4% | Reduced |
| Point72 Asset Management, L.P. | 1,207,220 | $43.8M | 0.07% | −592,408−32.9% | Reduced |
| Janus Henderson Group PLC | 1,213,265 | $44.0M | 0.02% | +1,193,417+6,012.8% | Added |
| Geode Capital Management, LLC | 1,257,582 | $45.6M | 0.00% | +134,171+11.9% | Added |
| Jennison Associates LLC | 1,258,653 | $45.7M | 0.03% | +882,307+234.4% | Added |
| Samlyn Capital, LLC | 1,304,932 | $47.4M | 0.76% | +1,304,932 | New |
| Price T Rowe Associates Inc | 1,325,120 | $48.1M | 0.01% | +1,303,737+6,097.1% | Added |
| Polar Capital Holdings Plc | 1,401,141 | $50.8M | 0.23% | +342,365+32.3% | Added |
| Goldman Sachs Group Inc | 1,450,933 | $52.7M | 0.01% | +739,272+103.9% | Added |
| Suvretta Capital Management, LLC | 1,538,662 | $55.8M | 1.39% | −593,471−27.8% | Reduced |
| Sr One Capital Management, LP | 1,563,966 | $56.8M | 8.03% | −549,967−26.0% | Reduced |
| Andera Partners | 1,591,917 | $57.8M | 32.71% | +1,591,917 | New |
| Holocene Advisors, LP | 1,602,035 | $58.1M | 0.12% | +396,658+32.9% | Added |
| Laurion Capital Management LP | 1,713,485 | $62.2M | 4.24% | −6,960−0.4% | Reduced |
| Franklin Resources Inc | 1,788,747 | $64.9M | 0.02% | −21,021−1.2% | Reduced |
| Caligan Partners LP | 2,772,654 | $100.6M | 9.21% | 00.0% | Unchanged |
| State Street Corp | 3,184,999 | $115.6M | 0.00% | +1,881,976+144.4% | Added |
| Vanguard Group Inc | 3,352,880 | $121.7M | 0.00% | +333,881+11.1% | Added |
| BlackRock, Inc. | 4,327,678 | $157.1M | 0.00% | +656,064+17.9% | Added |
| FMR LLC | 5,057,509 | $183.5M | 0.01% | +2,986,254+144.2% | Added |
| Samsara BioCapital, LLC | 5,871,018 | $213.1M | 21.98% | −392,133−6.3% | Reduced |
| Ra Capital Management, L.P. | 7,323,750 | $265.8M | 2.72% | 00.0% | Unchanged |
| Catalys Pacific, LLC | 7,903,838 | $286.8M | 92.37% | −1,000,000−11.2% | Reduced |
| Nearwater Capital Markets, Ltd | 0 | $0 | 0.00% | −450,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Atika Capital Management LLC | 0 | $0 | 0.00% | −174,000−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −120,854−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −105,000−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −75,768−100.0% | Sold out |
| Capstone Investment Advisors, LLC | 0 | $0 | 0.00% | −42,276−100.0% | Sold out |
| Resolute Capital Asset Partners LLC | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −37,145−100.0% | Sold out |
| Mark Asset Management LP | 0 | $0 | 0.00% | −19,465−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −15,268−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −13,000−100.0% | Sold out |
| Oxford Asset Management LLP | 0 | $0 | 0.00% | −9,123−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −7,964−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −6,670−100.0% | Sold out |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −6,338−100.0% | Sold out |
| Letko, Brosseau & Associates Inc | 0 | $0 | 0.00% | −5,475−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −39−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −37−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −21−100.0% | Sold out |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| FSA Wealth Management LLC | – | – | – | – | Not filed |