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Metagenomi Therapeutics, Inc.

MGX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001785279

In the last 90 days, Metagenomi Therapeutics, Inc. insiders filed 1 open-market purchase and 3 sales; 43 institutions reported holding it in 13F filings for Q2 2026, worth $7.45M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Metagenomi Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
56
+2 vs. Q3 2025
Shares held
6.76M
+1.36M (+25.1%) vs. Q3 2025
Total value
$11.0M
−$1.85M (−14.5%) vs. Q3 2025
New holders
11
13 more added
Sold out
9
18 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 56 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 50 institutionsQ2 2024: 54 institutionsQ3 2024: 67 institutionsQ4 2024: 77 institutionsQ1 2025: 79 institutionsQ2 2025: 69 institutionsQ3 2025: 58 institutionsQ4 2025: 56 institutionsQ1 2026: 48 institutionsQ2 2026: 43 institutions
Value heldQ4 2025: $11.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $140.3MQ2 2024: $49.6MQ3 2024: $25.3MQ4 2024: $38.8MQ1 2025: $13.5MQ2 2025: $10.4MQ3 2025: $14.2MQ4 2025: $11.0MQ1 2026: $8.65MQ2 2026: $7.45M
Institutions holding MGX and their total value by quarter
QuarterHoldersValue
Q2 202643$7.45M
Q1 202648$8.65M
Q4 202556$11.0M
Q3 202558$14.2M
Q2 202569$10.4M
Q1 202579$13.5M
Q4 202477$38.8M
Q3 202467$25.3M
Q2 202454$49.6M
Q1 202450$140.3M
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Metagenomi Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding MGX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc1,270,246$2.06M0.00%+28,736+2.3%Added
Renaissance Technologies LLC628,400$1.02M0.00%+461,400+276.3%Added
Catalio Capital Management, LP528,993$857.0K0.15%00.0%Unchanged
Peapod Lane Capital LLC497,653$806.2K0.69%−16,162−3.1%Reduced
Two Sigma Investments, LP441,388$715.0K0.00%+233,860+112.7%Added
Jane Street Group, LLC433,859$702.9K0.00%+335,604+341.6%Added
Bridgeway Capital Management, LLC395,800$641.2K0.01%+200,000+102.1%Added
Geode Capital Management, LLC305,908$495.8K0.00%+14,018+4.8%Added
Pura Vida Investments, LLC264,391$428.3K1.60%00.0%Unchanged
Millennium Management LLC235,185$381.0K0.00%−75,507−24.3%Reduced
BlackRock, Inc.224,141$363.1K0.00%+690+0.3%Added
Two Sigma Advisers, LP201,300$326.1K0.00%+150,900+299.4%Added
Citadel Advisors LLC178,172$288.6K0.00%+178,172New
State Street Corp120,427$195.1K0.00%−1,110−0.9%Reduced
Wells Fargo & Company118,410$191.8K0.00%+16,402+16.1%Added
Resolute Partners Group89,944$145.7K0.05%00.0%Unchanged
Marshall Wace, LLP79,136$128.2K0.00%−12,169−13.3%Reduced
Northern Trust Corp75,172$121.8K0.00%+35,198+88.1%Added
XTX Topco Ltd68,994$111.8K0.00%+53,778+353.4%Added
Acadian Asset Management LLC64,875$105.0K0.00%+64,875New
RBF Capital, LLC64,021$103.7K0.00%−6,759−9.5%Reduced
Morgan Stanley59,682$96.7K0.00%−181,652−75.3%Reduced
Man Group plc56,497$91.5K0.00%+3,609+6.8%Added
BBR Partners, LLC53,403$86.5K0.00%00.0%Unchanged
Fortitude Advisory Group L.L.C.38,740$62.8K0.03%00.0%Unchanged
Quadrature Capital Ltd33,917$54.9K0.00%+33,917New
Panagora Asset Management Inc32,580$52.8K0.00%+32,580New
Point72 Asset Management, L.P.26,589$43.1K0.00%+26,589New
UBS Group AG25,099$40.7K0.00%+1,611+6.9%Added
Dynamic Technology Lab Private Ltd23,762$38.0K0.01%−3,416−12.6%Reduced
JustInvest LLC16,298$26.4K0.00%−5,224−24.3%Reduced
Dimensional Fund Advisors LP13,783$22.3K0.00%+13,783New
Peak Planning Group, LLC12,500$20.3K0.01%+12,500New
Two Sigma Securities, LLC11,700$19.0K0.00%−489−4.0%Reduced
LPL Financial LLC11,297$18.3K0.00%+11,297New
Squarepoint Ops LLC10,594$17.2K0.00%+10,594New
HRT Financial LP11,091$17.0K0.00%−3,006−21.3%Reduced
Tower Research Capital LLC (TRC)9,303$15.1K0.00%+9,303New
Russell Investments Group, Ltd.7,136$11.6K0.00%00.0%Unchanged
FMR LLC6,808$11.0K0.00%−3,388−33.2%Reduced
Meeder Asset Management Inc5,496$8.90K0.00%00.0%Unchanged
US Bancorp4,500$7.29K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.2,891$4.68K0.00%−250−8.0%Reduced
JPMorgan Chase & Co1,596$2.58K0.00%−60,963−97.4%Reduced
Massmutual Trust Co FSB593$9610.00%00.0%Unchanged
Nisa Investment Advisors, LLC511$8280.00%00.0%Unchanged
Jones Financial Companies LLLP500$8100.00%00.0%Unchanged
Allworth Financial LP500$8100.00%+500New
BNP Paribas Arbitrage, SA307$4970.00%−14,864−98.0%Reduced
Larson Financial Group LLC50$810.00%00.0%Unchanged
Bank of America Corp42$680.00%−18,724−99.8%Reduced
Optiver Holding B.V.18$290.00%00.0%Unchanged
SRS Capital Advisors, Inc.11$180.00%−19−63.3%Reduced
Barclays PLC3$50.00%00.0%Unchanged
Royal Bank of Canada23$00.00%−592−96.3%Reduced
CWM, LLC32$00.00%−1−3.0%Reduced
Walleye Capital LLC0$00.00%−71,266−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−34,169−100.0%Sold out
Tang Capital Management LLC0$00.00%−28,008−100.0%Sold out
Marex Group plc0$00.00%−15,000−100.0%Sold out
Green Alpha Advisors, LLC0$00.00%−14,252−100.0%Sold out
Citigroup Inc0$00.00%−3,314−100.0%Sold out
UMA Financial Services, Inc.0$00.00%−610−100.0%Sold out
Principal Securities, Inc.0$00.00%−544−100.0%Sold out
Rialto Wealth Management, LLC0$00.00%−305−100.0%Sold out
Sozo Ventures GP II, L.P.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Point72 (DIFC) Ltd––––Not filed