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Macrogenics Inc

MGNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001125345

In the last 90 days, Macrogenics Inc insiders filed 0 open-market purchases and 1 sale; 122 institutions reported holding it in 13F filings for Q2 2026, worth $224.9M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Macrogenics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
89
−11 vs. Q3 2025
Shares held
40.0M
−5.95M (−13.0%) vs. Q3 2025
Total value
$64.3M
−$12.8M (−16.6%) vs. Q3 2025
New holders
13
29 more added
Sold out
24
27 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MGNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 89 institutions
Q1 2021: 174 institutionsQ2 2021: 149 institutionsQ3 2021: 154 institutionsQ4 2021: 156 institutionsQ1 2022: 144 institutionsQ2 2022: 133 institutionsQ3 2022: 135 institutionsQ4 2022: 135 institutionsQ1 2023: 137 institutionsQ2 2023: 131 institutionsQ3 2023: 127 institutionsQ4 2023: 143 institutionsQ1 2024: 163 institutionsQ2 2024: 147 institutionsQ3 2024: 124 institutionsQ4 2024: 129 institutionsQ1 2025: 129 institutionsQ2 2025: 112 institutionsQ3 2025: 104 institutionsQ4 2025: 89 institutionsQ1 2026: 109 institutionsQ2 2026: 122 institutions
Value heldQ4 2025: $64.3M
Q1 2021: $1.80BQ2 2021: $1.54BQ3 2021: $1.21BQ4 2021: $918.1MQ1 2022: $531.2MQ2 2022: $184.9MQ3 2022: $199.0MQ4 2022: $380.5MQ1 2023: $419.1MQ2 2023: $321.1MQ3 2023: $270.5MQ4 2023: $595.1MQ1 2024: $953.6MQ2 2024: $258.9MQ3 2024: $187.9MQ4 2024: $182.5MQ1 2025: $68.3MQ2 2025: $58.5MQ3 2025: $77.4MQ4 2025: $64.3MQ1 2026: $124.8MQ2 2026: $224.9M
Institutions holding MGNX and their total value by quarter
QuarterHoldersValue
Q2 2026122$224.9M
Q1 2026109$124.8M
Q4 202589$64.3M
Q3 2025104$77.4M
Q2 2025112$58.5M
Q1 2025129$68.3M
Q4 2024129$182.5M
Q3 2024124$187.9M
Q2 2024147$258.9M
Q1 2024163$953.6M
Q4 2023143$595.1M
Q3 2023127$270.5M
Q2 2023131$321.1M
Q1 2023137$419.1M
Q4 2022135$380.5M
Q3 2022135$199.0M
Q2 2022133$184.9M
Q1 2022144$531.2M
Q4 2021156$918.1M
Q3 2021154$1.21B
Q2 2021149$1.54B
Q1 2021174$1.80B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Macrogenics Inc; share changes are against Q3 2025.

Institutions holding MGNX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Armistice Capital, LLC6,324,000$10.2M0.25%+364,000+6.1%Added
Vanguard Group Inc4,226,941$6.81M0.00%+2,707+0.1%Added
Renaissance Technologies LLC2,908,631$4.68M0.01%+1,207,408+71.0%Added
Acadian Asset Management LLC2,518,410$4.05M0.01%+8630.0%Added
Millennium Management LLC1,974,480$3.18M0.00%−142,390−6.7%Reduced
Jefferies Financial Group Inc.1,841,172$2.96M0.02%+1,841,172New
Bank of America Corp1,837,720$2.96M0.00%+1,628,274+777.4%Added
Wasatch Advisors Inc1,786,356$2.88M0.02%−163,931−8.4%Reduced
Marshall Wace, LLP1,284,563$2.07M0.00%+655,028+104.0%Added
Jane Street Group, LLC1,254,923$2.02M0.00%+408,229+48.2%Added
Two Sigma Advisers, LP1,195,000$1.92M0.00%+446,400+59.6%Added
BlackRock, Inc.1,152,649$1.86M0.00%−386,045−25.1%Reduced
Citadel Advisors LLC1,035,153$1.67M0.00%+541,622+109.7%Added
Two Sigma Investments, LP999,474$1.61M0.00%+562,383+128.7%Added
Jacobs Levy Equity Management, Inc901,057$1.45M0.01%+85,192+10.4%Added
Connor, Clark & Lunn Investment Management Ltd.818,820$1.32M0.00%+108,212+15.2%Added
D. E. Shaw & Co., Inc.756,647$1.22M0.00%+534,447+240.5%Added
Geode Capital Management, LLC655,300$1.06M0.00%−2,221−0.3%Reduced
Gsa Capital Partners LLP511,004$823.0K0.07%+450,203+740.5%Added
Affinity Asset Advisors, LLC484,308$779.7K0.06%+484,308New
Nomura Asset Management International Inc.420,000$676.0K0.00%+420,000New
Squarepoint Ops LLC312,424$503.0K0.00%−73,209−19.0%Reduced
Pinnacle Associates Ltd292,696$471.2K0.01%−45,410−13.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH300,000$468.0K0.00%+90,000+42.9%Added
Vestal Point Capital, LP280,000$450.8K0.02%00.0%Unchanged
State Street Corp274,587$442.1K0.00%00.0%Unchanged
Quadrature Capital Ltd265,465$427.4K0.00%+222,751+521.5%Added
Point72 Asset Management, L.P.249,157$401.1K0.00%+249,157New
XTX Topco Ltd240,327$386.9K0.01%+66,368+38.2%Added
Amundi214,278$345.0K0.00%+214,278New
Mackenzie Financial Corp207,879$323.7K0.00%+207,879New
HRT Financial LP190,095$306.0K0.00%+190,095New
Dimensional Fund Advisors LP187,775$302.1K0.00%−157,807−45.7%Reduced
Goldman Sachs Group Inc181,706$292.5K0.00%−76,956−29.8%Reduced
Morgan Stanley161,016$259.2K0.00%−828,217−83.7%Reduced
Canada Pension Plan Investment Board155,200$249.9K0.00%+155,200New
Northern Trust Corp152,672$245.8K0.00%+1,531+1.0%Added
Panagora Asset Management Inc150,061$241.6K0.00%+88,861+145.2%Added
UBS Group AG119,447$192.3K0.00%+71,661+150.0%Added
Invesco Ltd.111,121$178.9K0.00%+26,668+31.6%Added
Leonteq Securities AG100,000$161.0K0.01%00.0%Unchanged
Ameriprise Financial Inc92,853$149.5K0.00%−2,422−2.5%Reduced
Bridgeway Capital Management, LLC81,200$130.7K0.00%−7,500−8.5%Reduced
Timothy G. Youngquist 2020 Irrevocable Trust79,113$127.4K0.11%+79,113New
Ikarian Capital, LLC74,893$120.6K0.02%−5,178−6.5%Reduced
Susquehanna International Group, LLP68,541$110.4K0.00%−155,252−69.4%Reduced
LPL Financial LLC65,125$104.9K0.00%+41,967+181.2%Added
FMR LLC62,299$100.3K0.00%−1,035−1.6%Reduced
Public Employees Retirement System of Ohio42,382$68.2K0.00%00.0%Unchanged
Barclays PLC41,350$66.6K0.00%+2,044+5.2%Added
AlphaCore Capital LLC38,073$61.3K0.00%+38,073New
Walleye Capital LLC33,180$53.4K0.00%+8,000+31.8%Added
SEI Investments Co31,318$50.4K0.00%00.0%Unchanged
Rangeley Capital, LLC30,220$48.7K0.04%00.0%Unchanged
XML Financial, LLC25,336$40.8K0.00%−7,000−21.6%Reduced
Prudential Financial Inc22,600$36.4K0.00%+800+3.7%Added
Boothbay Fund Management, LLC18,334$29.5K0.00%−5,178−22.0%Reduced
Evercore Wealth Management, LLC17,543$28.2K0.00%00.0%Unchanged
Tudor Investment Corp Et Al16,429$26.5K0.00%00.0%Unchanged
R Squared Ltd15,891$25.6K0.01%+15,891New
JustInvest LLC12,780$20.6K0.00%+2,201+20.8%Added
CI Private Wealth, LLC11,822$19.0K0.00%−2,802−19.2%Reduced
Sound Income Strategies, LLC7,262$12.5K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.6,460$10.4K0.00%−15−0.2%Reduced
JPMorgan Chase & Co5,753$9.26K0.00%−749,492−99.2%Reduced
Simplex Trading, LLC5,097$8.21K0.00%−2,027−28.5%Reduced
Wells Fargo & Company3,000$4.83K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd1,464$2.36K0.00%+1,331+1,000.8%Added
Russell Investments Group, Ltd.1,277$2.06K0.00%−47,828−97.4%Reduced
IMG Wealth Management, Inc.1,150$1.85K0.00%00.0%Unchanged
Truvestments Capital LLC1,008$1.62K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)978$1.57K0.00%−15,785−94.2%Reduced
BNP Paribas Arbitrage, SA694$1.12K0.00%−85,977−99.2%Reduced
Spire Wealth Management664$1.07K0.00%00.0%Unchanged
Cornerstone Planning Group LLC560$1.01K0.00%00.0%Unchanged
Royal Bank of Canada879$1.00K0.00%+404+85.1%Added
HighMark Wealth Management LLC400$6440.00%00.0%Unchanged
Nisa Investment Advisors, LLC347$5590.00%−152−30.5%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP213$3920.00%00.0%Unchanged
Clear Street Markets LLC124$2000.00%+124New
Farmers & Merchants Investments Inc80$1290.00%00.0%Unchanged
SBI Securities Co., Ltd.59$950.00%−3,000−98.1%Reduced
SRS Capital Advisors, Inc.55$890.00%+46+511.1%Added
Comerica Bank44$710.00%00.0%Unchanged
Jones Financial Companies LLLP30$480.00%00.0%Unchanged
Rockefeller Capital Management L.P.25$400.00%00.0%Unchanged
CWM Advisors, LLC14$230.00%+14New
CWM, LLC243$00.00%−749−75.5%Reduced
Covestor Ltd55$00.00%−1−1.8%Reduced
Bellevue Group AG0$00.00%−9,919,992−100.0%Sold out
Frazier Life Sciences Management, L.P.0$00.00%−3,175,665−100.0%Sold out
Macquarie Group Ltd0$00.00%−420,000−100.0%Sold out
Voleon Capital Management LP0$00.00%−307,395−100.0%Sold out
Tang Capital Management LLC0$00.00%−218,856−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−160,000−100.0%Sold out
Algert Global LLC0$00.00%−88,130−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−54,600−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−30,008−100.0%Sold out
Stifel Financial Corp0$00.00%−23,920−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−22,415−100.0%Sold out